Page last updated: 2024-10-16

choline and Brain Edema

choline has been researched along with Brain Edema in 33 studies

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"Brain alterations such as hepatic encephalopathy or brain edema are usually associated with liver failure."2.50Magnetic resonance of the brain in chronic and acute liver failure. ( Chavarria, L; Cordoba, J, 2014)
"Brain edema was maximal on MR imaging 3 h after poisoning."1.42Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model. ( Cohen, Y; Eisenkraft, A; Kadar, T; Kassirer, M; Milk, N; Rosman, Y; Shiyovich, A; Shrot, S; Tauber, M, 2015)
"Heroin could be a cause more common than thought of leukoencephalopathy."1.38[Toxic leucoencephalopathy after use of sniffed heroin, an unrecognized form of beneficial evolution]. ( Cotton, F; Drouet, A; Felten, D; Guilloton, L; Havé, L; Lamboley, JL; Quesnel, L; St-Pierre, G, 2012)
"Glycine (100 microM) was inactive in this assay indicating an absence of functional glycine-A receptors in this preparation."1.35Role of glycine receptors and glycine release for the neuroprotective activity of bilobalide. ( Hartmann, J; Hildmann, O; Hillert, M; Kiewert, C; Klein, J; Kumar, V, 2008)
"Subclinical cerebral edema occurs in many, if not most, children with diabetic ketoacidosis (DKA) and may be an indicator of subtle brain injury."1.34Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis. ( Barnes, PD; Buonocore, MH; DiCarlo, J; Glaser, NS; Kuppermann, N; Marcin, JP; McCarthy, T; Neely, EK; Wootton-Gorges, SL, 2007)
"PEHO syndrome is a rare symptom complex of severe progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy."1.33Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. ( Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B, 2006)
"Hyperforin (10 microM) was found to inhibit the NMDA-induced calcium influx into cortical neurons."1.33NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort. ( Abbruscato, T; Bickel, U; Kiewert, C; Klein, J; Kumar, V; Mdzinarishvili, A; van der Schyf, CJ, 2006)
"Choline peak area was increased in tumor, creatine and N-acetyl aspartate were decreased in edema and tumor compared with unaffected brain tissue."1.311H chemical shift imaging characterization of human brain tumor and edema. ( Oudkerk, M; Sijens, PE, 2002)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.12)18.7374
1990's8 (24.24)18.2507
2000's12 (36.36)29.6817
2010's9 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chavarria, L2
Cordoba, J2
Parra, NA1
Maudsley, AA1
Gupta, RK3
Ishkanian, F1
Huang, K1
Walker, GR1
Padgett, K1
Roy, B1
Panoff, J1
Markoe, A1
Stoyanova, R1
Shrot, S1
Tauber, M1
Shiyovich, A1
Milk, N1
Rosman, Y1
Eisenkraft, A1
Kadar, T1
Kassirer, M1
Cohen, Y1
Tian, R1
Han, L1
Hou, Z1
Hao, S1
Mao, X1
Zhu, Z1
Tao, X1
Zhang, Q1
Liu, B1
Chernov, MF1
Nakaya, K1
Kasuya, H1
Kato, K1
Ono, Y1
Yoshida, S1
Nakamura, R1
Suzuki, T1
Muragaki, Y1
Iseki, H1
Kubo, O1
Hori, T1
Takakura, K1
Lescot, T1
Fulla-Oller, L2
Po, C1
Chen, XR1
Puybasset, L1
Gillet, B1
Plotkine, M1
Meric, P1
Marchand-Leroux, C1
Havé, L1
Drouet, A1
Lamboley, JL1
Cotton, F1
St-Pierre, G1
Quesnel, L1
Guilloton, L1
Felten, D1
Srivastava, A1
Yadav, SK1
Borkar, VV1
Yadav, A1
Yachha, SK1
Thomas, MA1
Rathore, RK1
Pandey, CM1
Righi, V1
Tugnoli, V1
Mucci, A1
Bacci, A1
Bonora, S1
Schenetti, L1
Alonso, J1
García-Martínez, R1
Simón-Talero, M1
Ventura-Cots, M1
Ramírez, C1
Torrens, M1
Vargas, V1
Rovira, A1
Sijens, PE1
Oudkerk, M1
Briellmann, RS1
Wellard, RM1
Jackson, GD1
Alexander, JJ1
Zwingmann, C1
Quigg, R1
Boichot, C1
Walker, PM1
Durand, C1
Grimaldi, M1
Chapuis, S1
Gouyon, JB1
Brunotte, F1
Huisman, TA1
Klein, A1
Werner, B1
Straube, T1
Boltshauser, E1
Kumar, V3
Mdzinarishvili, A1
Kiewert, C3
Abbruscato, T1
Bickel, U1
van der Schyf, CJ1
Klein, J3
Hildmann, O2
Rueda, M1
Hartmann, J2
Naik, RS1
Wootton-Gorges, SL1
Buonocore, MH1
Kuppermann, N1
Marcin, JP1
Barnes, PD1
Neely, EK1
DiCarlo, J1
McCarthy, T1
Glaser, NS1
Hillert, M1
Nukata, T1
Ando, N1
Yoshida, H1
Gyngell, ML1
Els, T1
Hoehn-Berlage, M1
Hossmann, KA1
Kamada, K1
Houkin, K1
Hida, K1
Matsuzawa, H1
Iwasaki, Y1
Abe, H1
Nakada, T1
Kimura, H1
Grossman, RI1
Lenkinski, RE1
Gonzalez-Scarano, F1
Chumas, P1
Condon, B1
Oluoch-Olunya, D1
Griffiths, S1
Hadley, D1
Teasdale, G1
Sengar, AR1
Dhanuka, AK1
Roy, R1
Das, K1
Wardlaw, JM1
Marshall, I1
Wild, J1
Dennis, MS1
Cannon, J1
Lewis, SC1
Phillis, JW1
Song, D1
O'Regan, MH1
Horská, A1
Ulug, AM1
Melhem, ER1
Filippi, CG1
Burger, PC1
Edgar, MA1
Souweidane, MM1
Carson, BS1
Barker, PB1
Schuhmann, MU1
Stiller, D1
Thomas, S1
Brinker, T1
Samii, M1
Cohadon, F1
Rigoulet, M1
Guérin, B1
Vandendriessche, M1
Cervós-Navarro, J1
Lafuente, JV1
Matsuoka, T1
Shirai, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Magnetic Resonance Imaging in Detection of Minimal Hepatic Encephalopathy[NCT04131205]40 participants (Anticipated)Observational2019-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for choline and Brain Edema

ArticleYear
Magnetic resonance of the brain in chronic and acute liver failure.
    Metabolic brain disease, 2014, Volume: 29, Issue:4

    Topics: Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Edema; Choline; Creatine; Glutamic Acid; Gl

2014
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
    Epilepsia, 2005, Volume: 46, Issue:5

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn

2005

Trials

1 trial available for choline and Brain Edema

ArticleYear
Brain magnetic resonance spectroscopy in episodic hepatic encephalopathy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:2

    Topics: Aged; Brain; Brain Chemistry; Brain Edema; Choline; Female; Follow-Up Studies; Glutamic Acid; Hepati

2013

Other Studies

30 other studies available for choline and Brain Edema

ArticleYear
Volumetric spectroscopic imaging of glioblastoma multiforme radiation treatment volumes.
    International journal of radiation oncology, biology, physics, 2014, Oct-01, Volume: 90, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Brain; Brain Edema; Brain Mapping; Brain Neoplasms; Choline; Creatine; F

2014
Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model.
    Neurotoxicology, 2015, Volume: 48

    Topics: Animals; Aspartic Acid; Atropine; Behavior, Animal; Brain; Brain Edema; Choline; Cholinesterase Reac

2015
Neuroprotective efficacy of decompressive craniectomy after controlled cortical impact injury in rats: An MRI study.
    Brain research, 2015, Oct-05, Volume: 1622

    Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Choline; Creatine; Decompressive Craniec

2015
Metabolic alterations in the peritumoral brain in cases of meningiomas: 1H-MRS study.
    Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

    Topics: Adult; Aged; Aspartic Acid; Brain; Brain Edema; Choline; Female; Humans; Lactic Acid; Lipids; Magnet

2009
Temporal and regional changes after focal traumatic brain injury.
    Journal of neurotrauma, 2010, Volume: 27, Issue:1

    Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Brain Mapping; Cerebral Cortex; Choline;

2010
[Toxic leucoencephalopathy after use of sniffed heroin, an unrecognized form of beneficial evolution].
    Revue neurologique, 2012, Volume: 168, Issue:1

    Topics: Administration, Inhalation; Biopsy; Brain Chemistry; Brain Edema; Choline; Cognition Disorders; Demy

2012
Serial evaluation of children with ALF with advanced MRI, serum proinflammatory cytokines, thiamine, and cognition assessment.
    Journal of pediatric gastroenterology and nutrition, 2012, Volume: 55, Issue:5

    Topics: Brain; Brain Edema; Case-Control Studies; Child; Child, Preschool; Choline; Cognition; Cognition Dis

2012
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
    Oncology reports, 2012, Volume: 28, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat

2012
1H chemical shift imaging characterization of human brain tumor and edema.
    European radiology, 2002, Volume: 12, Issue:8

    Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Choline; Creatine; Humans; Hydrogen; Magnetic Resonance

2002
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
    Neurochemistry international, 2005, Volume: 47, Issue:1-2

    Topics: Alanine; Amino Acids; Animals; Brain; Brain Diseases, Metabolic; Brain Edema; Carbon Radioisotopes;

2005
Term neonate prognoses after perinatal asphyxia: contributions of MR imaging, MR spectroscopy, relaxation times, and apparent diffusion coefficients.
    Radiology, 2006, Volume: 239, Issue:3

    Topics: Age Factors; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Brain Edema; Cause of Death; Cerebra

2006
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion

2006
NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort.
    Journal of pharmacological sciences, 2006, Volume: 102, Issue:1

    Topics: Animals; Brain Edema; Brain Ischemia; Bridged Bicyclo Compounds; Calcium; Choline; Hippocampus; Hype

2006
Role of GABAergic antagonism in the neuroprotective effects of bilobalide.
    Brain research, 2007, Jan-12, Volume: 1128, Issue:1

    Topics: Animals; Area Under Curve; Bicuculline; Brain Edema; Bridged Bicyclo Compounds, Heterocyclic; Cholin

2007
Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:5

    Topics: Adolescent; Aspartic Acid; Brain; Brain Edema; Child; Choline; Consciousness Disorders; Creatine; Di

2007
Role of glycine receptors and glycine release for the neuroprotective activity of bilobalide.
    Brain research, 2008, Mar-27, Volume: 1201

    Topics: Animals; Binding Sites; Binding, Competitive; Brain Edema; Brain Ischemia; Chlorides; Choline; Cyclo

2008
[Studies on swelling of the cerebral cortex slices].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1967, Mar-20, Volume: 63, Issue:2

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Biological Transport, Active; Brain Edema; Carbon Isot

1967
Proton MR spectroscopy of experimental brain tumors in vivo.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Animals; Aspartic Acid; Blood Glucose; Brain Edema; Brain Neoplasms; Caudate Nucleus; Cell Line; Cho

1994
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr

1994
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease.
    AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:8

    Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyel

1996
Early changes in peritumorous oedema and contralateral white matter after dexamethasone: a study using proton magnetic resonance spectroscopy.
    Journal of neurology, neurosurgery, and psychiatry, 1997, Volume: 62, Issue:6

    Topics: Antineoplastic Agents, Hormonal; Aspartic Acid; Brain; Brain Edema; Brain Neoplasms; Choline; Creati

1997
MR imaging, MR angiography, and MR spectroscopy of the brain in eclampsia.
    AJNR. American journal of neuroradiology, 1997, Volume: 18, Issue:8

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Choline; Cr

1997
Studies of acute ischemic stroke with proton magnetic resonance spectroscopy: relation between time from onset, neurological deficit, metabolite abnormalities in the infarct, blood flow, and clinical outcome.
    Stroke, 1998, Volume: 29, Issue:8

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Edema; B

1998
Effects of hyperosmolarity and ion substitutions on amino acid efflux from the ischemic rat cerebral cortex.
    Brain research, 1999, May-15, Volume: 828, Issue:1-2

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain Edema; Brain Ischemia; Cerebral Cortex; Chlorides

1999
Proton magnetic resonance spectroscopy of choroid plexus tumors in children.
    Journal of magnetic resonance imaging : JMRI, 2001, Volume: 14, Issue:1

    Topics: Aspartic Acid; Brain Edema; Child, Preschool; Choline; Choroid Plexus; Choroid Plexus Neoplasms; Dia

2001
1H-MR spectroscopic monitoring of posttraumatic metabolism following controlled cortical impact injury: pilot study.
    Acta neurochirurgica. Supplement, 2000, Volume: 76

    Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Cerebral Cortex; Choline; Creatine; Energy Me

2000
[Vasogenic cerebral oedema. Changes in membrane ATPases. Correction by a phospholipid precursor (author's transl)].
    La Nouvelle presse medicale, 1979, Apr-28, Volume: 8, Issue:19

    Topics: Adenosine Triphosphatases; Animals; Brain Edema; Cell Membrane; Choline; Cytidine Diphosphate Cholin

1979
Effect of cytidine diphosphate choline on ultraviolet-induced brain edema.
    Advances in neurology, 1990, Volume: 52

    Topics: Animals; Body Water; Brain Chemistry; Brain Edema; Cats; Choline; Cytidine Diphosphate Choline; Radi

1990
[Quantitative evaluation of drug effects on brain edema].
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1969, Sep-01, Volume: 38, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Brain Edema; Choline; Cytosine Nucleotides; Glucose; Mannitol; Pre

1969
[Experimental studies on ligation of superior sagittal sinus].
    Kumamoto Igakkai zasshi. The Journal of the Kumamoto Medical Society, 1969, Sep-25, Volume: 43, Issue:9

    Topics: Animals; Brain Edema; Choline; Cranial Sinuses; Dogs; Electroencephalography; Intracranial Pressure;

1969