choline has been researched along with Autistic Disorder in 23 studies
Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The safety and efficacy of a novel combination treatment of AChE inhibitors and choline supplement was initiated and evaluated in children and adolescents with autism spectrum disorder (ASD)." | 9.30 | Improvement of Language in Children with Autism with Combined Donepezil and Choline Treatment. ( Ben-Hur, R; Gabis, LV; Jokel, A; Shalom, DB; Shefer, S, 2019) |
| " We report an association between hydrogen proton magnetic resonance spectroscopy choline/creatine ratios and severity of autism as measured by the Children's Autistic Rating Scale (Pearson r = ." | 7.71 | Hydrogen proton magnetic resonance spectroscopy in autism: preliminary evidence of elevated choline/creatine ratio. ( Dunn, DW; Edwards-Brown, M; Feinberg, J; Sokol, DK, 2002) |
| "Choline is a fundamental nutrient for brain development and high choline intake during prenatal and/or early postnatal periods is neuroprotective." | 5.42 | High maternal choline consumption during pregnancy and nursing alleviates deficits in social interaction and improves anxiety-like behaviors in the BTBR T+Itpr3tf/J mouse model of autism. ( Blusztajn, JK; Krykbaeva, M; Langley, EA; Mellott, TJ, 2015) |
| "The safety and efficacy of a novel combination treatment of AChE inhibitors and choline supplement was initiated and evaluated in children and adolescents with autism spectrum disorder (ASD)." | 5.30 | Improvement of Language in Children with Autism with Combined Donepezil and Choline Treatment. ( Ben-Hur, R; Gabis, LV; Jokel, A; Shalom, DB; Shefer, S, 2019) |
| "In 22 children with autism, 5 to 16 years old, and 20 age-matched healthy control subjects, (1)H-MRSI assessed levels of N-acetyl compounds (NAA), choline compounds (Cho), and creatine plus phosphocreatine (Cr) at 272 msec echo-time and 1." | 3.72 | Proton magnetic resonance spectroscopic imaging of the brain in childhood autism. ( Alger, JR; Blanton, RE; Fadale, D; Guthrie, D; Levitt, JG; McCracken, JT; O'Neill, J; Smalley, S; Toga, AW, 2003) |
| " We report an association between hydrogen proton magnetic resonance spectroscopy choline/creatine ratios and severity of autism as measured by the Children's Autistic Rating Scale (Pearson r = ." | 3.71 | Hydrogen proton magnetic resonance spectroscopy in autism: preliminary evidence of elevated choline/creatine ratio. ( Dunn, DW; Edwards-Brown, M; Feinberg, J; Sokol, DK, 2002) |
| "© 2015 International Society for Autism Research, Wiley Periodicals, Inc." | 1.43 | Biochemistry of the cingulate cortex in autism: An MR spectroscopy study. ( Kana, RK; Lahti, AC; Libero, LE; Reid, MA; Salibi, N; White, DM, 2016) |
| "Choline is a fundamental nutrient for brain development and high choline intake during prenatal and/or early postnatal periods is neuroprotective." | 1.42 | High maternal choline consumption during pregnancy and nursing alleviates deficits in social interaction and improves anxiety-like behaviors in the BTBR T+Itpr3tf/J mouse model of autism. ( Blusztajn, JK; Krykbaeva, M; Langley, EA; Mellott, TJ, 2015) |
| "Although autism spectrum disorders (ASDs) are highly heritable, MRS studies have not included relatives of persons with ASD." | 1.39 | Increased glutamate concentration in the auditory cortex of persons with autism and first-degree relatives: a (1)H-MRS study. ( Brown, MS; Hepburn, S; Rojas, DC; Singel, D, 2013) |
| "The diagnosis of autism was established by neurologist, psychiatrist and psychologist in every case." | 1.38 | Metabolite alterations in autistic children: a 1H MR spectroscopy study. ( Kubas, B; Kułak, W; Lebkowska, U; Sobaniec, W; Tarasow, E; Walecki, J, 2012) |
| "Choline/creatine was also significantly elevated in the left hippocampus-amygdala and cerebellar regions of children with autism spectrum disorder." | 1.35 | 1H-magnetic resonance spectroscopy markers of cognitive and language ability in clinical subtypes of autism spectrum disorders. ( Azizian, A; DeVincent, C; Gabis, L; Kesner-Baruch, Y; Pomeroy, J; Roche, P; Tudorica, A, 2008) |
| "Recent evidence indicates that autism is a disorder of the nervous system and the immune system, affecting multiple metabolic pathways." | 1.31 | Is autism a G-alpha protein defect reversible with natural vitamin A? ( Megson, MN, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 10 (43.48) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Grechanyi, SV | 1 |
| Suf El-Zhil, LR | 1 |
| Ivanov, DO | 1 |
| Pozdnyakova, OF | 1 |
| Sergeev, AM | 1 |
| Atamanova, EE | 1 |
| Pozdnyakov, AV | 1 |
| Jayaprakash, P | 1 |
| Isaev, D | 1 |
| Shabbir, W | 1 |
| Lorke, DE | 1 |
| Sadek, B | 1 |
| Oz, M | 1 |
| Gabis, LV | 1 |
| Ben-Hur, R | 1 |
| Shefer, S | 1 |
| Jokel, A | 1 |
| Shalom, DB | 1 |
| Langley, EA | 1 |
| Krykbaeva, M | 1 |
| Blusztajn, JK | 1 |
| Mellott, TJ | 1 |
| Wu, WL | 1 |
| Adams, CE | 1 |
| Stevens, KE | 1 |
| Chow, KH | 1 |
| Freedman, R | 1 |
| Patterson, PH | 1 |
| Libero, LE | 1 |
| Reid, MA | 1 |
| White, DM | 1 |
| Salibi, N | 1 |
| Lahti, AC | 1 |
| Kana, RK | 1 |
| Hardan, AY | 1 |
| Minshew, NJ | 1 |
| Melhem, NM | 1 |
| Srihari, S | 1 |
| Jo, B | 1 |
| Bansal, R | 1 |
| Keshavan, MS | 1 |
| Stanley, JA | 1 |
| Kleinhans, NM | 1 |
| Richards, T | 1 |
| Weaver, KE | 1 |
| Liang, O | 1 |
| Dawson, G | 3 |
| Aylward, E | 1 |
| Suzuki, K | 1 |
| Nishimura, K | 1 |
| Sugihara, G | 1 |
| Nakamura, K | 1 |
| Tsuchiya, KJ | 1 |
| Matsumoto, K | 1 |
| Takebayashi, K | 1 |
| Isoda, H | 1 |
| Sakahara, H | 1 |
| Sugiyama, T | 1 |
| Tsujii, M | 1 |
| Takei, N | 1 |
| Mori, N | 1 |
| Fujii, E | 1 |
| Mori, K | 2 |
| Miyazaki, M | 2 |
| Hashimoto, T | 3 |
| Harada, M | 3 |
| Kagami, S | 1 |
| Kubas, B | 1 |
| Kułak, W | 1 |
| Sobaniec, W | 1 |
| Tarasow, E | 1 |
| Lebkowska, U | 1 |
| Walecki, J | 1 |
| Brown, MS | 1 |
| Singel, D | 1 |
| Hepburn, S | 1 |
| Rojas, DC | 1 |
| Perich-Alsina, J | 1 |
| Aduna de Paz, M | 1 |
| Valls, A | 1 |
| Muñoz-Yunta, JA | 1 |
| Friedman, SD | 2 |
| Shaw, DW | 2 |
| Artru, AA | 2 |
| Richards, TL | 1 |
| Gardner, J | 1 |
| Posse, S | 1 |
| Dager, SR | 2 |
| Levitt, JG | 1 |
| O'Neill, J | 1 |
| Blanton, RE | 1 |
| Smalley, S | 1 |
| Fadale, D | 1 |
| McCracken, JT | 1 |
| Guthrie, D | 1 |
| Toga, AW | 1 |
| Alger, JR | 1 |
| Petropoulos, H | 1 |
| Vasconcelos, MM | 1 |
| Brito, AR | 1 |
| Domingues, RC | 1 |
| da Cruz, LC | 1 |
| Gasparetto, EL | 1 |
| Werner, J | 1 |
| Gonçalves, JP | 1 |
| Gabis, L | 1 |
| Azizian, A | 1 |
| DeVincent, C | 1 |
| Tudorica, A | 1 |
| Kesner-Baruch, Y | 1 |
| Roche, P | 1 |
| Pomeroy, J | 1 |
| Deutsch, SI | 1 |
| Stanley, M | 1 |
| Peselow, ED | 1 |
| Banay-Schwartz, M | 1 |
| Tayama, M | 1 |
| Yoneda, Y | 2 |
| Yoshimoto, T | 1 |
| Miyoshi, H | 1 |
| Tanouchi, M | 1 |
| Kuroda, Y | 1 |
| Kawano, N | 1 |
| Fukuda, K | 1 |
| Endo, S | 1 |
| Yamaue, T | 1 |
| Miyoshi, K | 1 |
| Megson, MN | 1 |
| Sokol, DK | 1 |
| Dunn, DW | 1 |
| Edwards-Brown, M | 1 |
| Feinberg, J | 1 |
1 review available for choline and Autistic Disorder
| Article | Year |
|---|---|
Glycine: a possible role in lithium's action and affective illness.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Autistic Disorder; Bipolar Disorder; Brain Chemistry; | 1983 |
2 trials available for choline and Autistic Disorder
| Article | Year |
|---|---|
Improvement of Language in Children with Autism with Combined Donepezil and Choline Treatment.
Topics: Adolescent; Autistic Disorder; Child; Choline; Donepezil; Drug Therapy, Combination; Female; Gastroi | 2019 |
Regional brain chemical alterations in young children with autism spectrum disorder.
Topics: Age Distribution; Age Factors; Aspartic Acid; Autistic Disorder; Brain; Cell Count; Child, Preschool | 2003 |
20 other studies available for choline and Autistic Disorder
| Article | Year |
|---|---|
[Proton magnetic resonance spectroscopy in children with atypical autism comorbid with psychomotor disinhibition syndrome].
Topics: Aspartic Acid; Autistic Disorder; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spect | 2021 |
Curcumin Potentiates α7 Nicotinic Acetylcholine Receptors and Alleviates Autistic-Like Social Deficits and Brain Oxidative Stress Status in Mice.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Autism Spectrum Disorder; A | 2021 |
High maternal choline consumption during pregnancy and nursing alleviates deficits in social interaction and improves anxiety-like behaviors in the BTBR T+Itpr3tf/J mouse model of autism.
Topics: Animals; Anxiety; Autistic Disorder; Behavior, Animal; Choline; Disease Models, Animal; Dose-Respons | 2015 |
The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Autistic Disorder; Behavior, Animal; Choline; Dise | 2015 |
Biochemistry of the cingulate cortex in autism: An MR spectroscopy study.
Topics: Adult; Aspartic Acid; Autistic Disorder; Choline; Creatine; Female; Gyrus Cinguli; Humans; Magnetic | 2016 |
An MRI and proton spectroscopy study of the thalamus in children with autism.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Child; Choline; Creatine; Dominance, Cerebral; Humans; | 2008 |
Brief report: biochemical correlates of clinical impairment in high functioning autism and Asperger's disorder.
Topics: Adolescent; Adult; Amygdala; Aspartic Acid; Asperger Syndrome; Autistic Disorder; Brain Mapping; Cas | 2009 |
Metabolite alterations in the hippocampus of high-functioning adult subjects with autism.
Topics: Adolescent; Adult; Aggression; Aspartic Acid; Autistic Disorder; Cerebellum; Choline; Creatine; Hipp | 2010 |
Function of the frontal lobe in autistic individuals: a proton magnetic resonance spectroscopic study.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Child; Child, Preschool; Choline; Creatine; Female; Fr | 2010 |
Metabolite alterations in autistic children: a 1H MR spectroscopy study.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Child; Choline; Creatine; Female; gamma-Aminobutyric A | 2012 |
Increased glutamate concentration in the auditory cortex of persons with autism and first-degree relatives: a (1)H-MRS study.
Topics: Adult; Auditory Cortex; Autistic Disorder; Choline; Creatine; Female; Glutamic Acid; Humans; Inosito | 2013 |
[Thalamic spectroscopy using magnetic resonance in autism].
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Child; Child, Preschool; Choline; Creatinine; Humans; | 2002 |
Proton magnetic resonance spectroscopic imaging of the brain in childhood autism.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Brain; Brain Mapping; Case-Control Studies; Child; Chi | 2003 |
Gray and white matter brain chemistry in young children with autism.
Topics: Aspartic Acid; Autistic Disorder; Brain; Brain Chemistry; Child, Preschool; Choline; Creatine; Cross | 2006 |
Proton magnetic resonance spectroscopy in school-aged autistic children.
Topics: Analysis of Variance; Aspartic Acid; Autistic Disorder; Brain; Brain Chemistry; Case-Control Studies | 2008 |
1H-magnetic resonance spectroscopy markers of cognitive and language ability in clinical subtypes of autism spectrum disorders.
Topics: Adolescent; Amygdala; Analysis of Variance; Aspartic Acid; Asperger Syndrome; Autistic Disorder; Bio | 2008 |
Differences in brain metabolites between patients with autism and mental retardation as detected by in vivo localized proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Autistic Disorder; Brain; Child; Child, Preschool; Choline; Creatine; Female; Humans; | 1997 |
Proton magnetic resonance spectroscopy of the brain in three cases of Rett syndrome: comparison with autism and normal controls.
Topics: Adolescent; Adult; Aspartic Acid; Autistic Disorder; Brain; Child; Child, Preschool; Choline; Creati | 1998 |
Is autism a G-alpha protein defect reversible with natural vitamin A?
Topics: Autistic Disorder; Child; Choline; GTP-Binding Proteins; Humans; Receptors, Retinoic Acid; Vitamin A | 2000 |
Hydrogen proton magnetic resonance spectroscopy in autism: preliminary evidence of elevated choline/creatine ratio.
Topics: Autistic Disorder; Brain; Child; Child, Preschool; Choline; Creatine; Female; Humans; Hydrogen Bondi | 2002 |