Page last updated: 2024-10-17

choline and Aura

choline has been researched along with Aura in 38 studies

Research Excerpts

ExcerptRelevanceReference
"The anticonvulsant effect of dicholine succinate (DCS), a neuronal insulin sensitizer, has been studied on two models of primary generalized epilepsy induced by corazole and maximal electroshock (ME) in mice."7.79[Anticonvulsant effect of dicholine succinate on primary generalized epilepsy model in mice]. ( Pomytkin, IA; Rychikhin, VM; Sariev, AK, 2013)
" We, therefore, utilized these methods to assess changes in glucose metabolism and metabolites in the rat lithium-pilocarpine model of epilepsy as markers of epileptogenesis from baseline to chronic spontaneous recurrent seizures (SRS)."7.78Changes in glucose metabolism and metabolites during the epileptogenic process in the lithium-pilocarpine model of epilepsy. ( Chung, JH; Im, KC; Kang, JK; Kim, JS; Kim, KS; Kim, ST; Kim, YI; Lee, EM; Park, GY; Shon, YM; Woo, CW, 2012)
"Seizure-experienced Genetically Epilepsy-prone Rats (GEPRs) have increased acetylcholine content and choline acetyltransferase activity in the thalamus and striatum."7.67Abnormalities in the central cholinergic transmitter system of the genetically epilepsy-prone rat. ( Hadjiconstantinou, M; Laird, HE; Neff, NH, 1986)
"The anticonvulsant effect of dicholine succinate (DCS), a neuronal insulin sensitizer, has been studied on two models of primary generalized epilepsy induced by corazole and maximal electroshock (ME) in mice."3.79[Anticonvulsant effect of dicholine succinate on primary generalized epilepsy model in mice]. ( Pomytkin, IA; Rychikhin, VM; Sariev, AK, 2013)
" We, therefore, utilized these methods to assess changes in glucose metabolism and metabolites in the rat lithium-pilocarpine model of epilepsy as markers of epileptogenesis from baseline to chronic spontaneous recurrent seizures (SRS)."3.78Changes in glucose metabolism and metabolites during the epileptogenic process in the lithium-pilocarpine model of epilepsy. ( Chung, JH; Im, KC; Kang, JK; Kim, JS; Kim, KS; Kim, ST; Kim, YI; Lee, EM; Park, GY; Shon, YM; Woo, CW, 2012)
"Metabolite maps of N-acetyl aspartate, choline and creatine were generated using (1)H-CSI data from the brain of healthy volunteers and patients with tumor and epilepsy."3.76Grid-free interactive and automated data processing for MR chemical shift imaging data. ( Confort-Gouny, S; Cozzone, PJ; Guye, M; Kober, F; Le Fur, Y; Nicoli, F, 2010)
"Seizure-experienced Genetically Epilepsy-prone Rats (GEPRs) have increased acetylcholine content and choline acetyltransferase activity in the thalamus and striatum."3.67Abnormalities in the central cholinergic transmitter system of the genetically epilepsy-prone rat. ( Hadjiconstantinou, M; Laird, HE; Neff, NH, 1986)
" Kainic acid (KA), a rigid structural analog of Glu, powerfully reproduces the excitatory neurotoxic (excitotoxic) action of Glu on central neurons and, in addition, causes sustained limbic seizures and a pattern of seizure-linked brain damage in rats that closely resembles that observed in human epilepsy."3.67Excitotoxic mechanisms of epileptic brain damage. ( Collins, RC; Olney, JW; Sloviter, RS, 1986)
"Choline is an essential nutrient for humans."2.49Neuroprotective actions of perinatal choline nutrition. ( Blusztajn, JK; Mellott, TJ, 2013)
"We present a case of infantile onset Krabbe disease with prolonged survival, initial intracranial optic nerves and optic chiasm hypertrophy, and serial changes on cranial magnetic resonance imaging and magnetic resonance spectroscopy."1.38Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease. ( Bunge, M; Mhanni, AA; Ryner, L; Salman, MS; Udow, S, 2012)
"Intracranial arachnoid cysts (ACs) are usually asymptomatic, benign developmental anomalies."1.35Single-voxel magnetic resonance spectroscopy of brain tissue adjacent to arachnoid cysts of epileptic patients. ( Ozcan, C; Ozisik, HI; Sarac, K, 2008)
"An association between complex febrile convulsions and the development of hippocampal atrophy, which is characterized by neuron loss and gliosis, has been suggested but is still controversial."1.30Proton spectroscopy in children with epilepsy and febrile convulsions. ( Holopainen, IE; Komu, ME; Lundbom, NM; Manner, TE; Sillanpää, ML; Sonninen, PH; Valtonen, ME, 1998)
"Physostigmine enhanced the increase in acetylcholine level but did not modify the time course nor the intensity of the convulsions."1.29Methionine sulfoximine increases acetylcholine level in the rat brain: no relation with epileptogenesis. ( Hevor, T; Richard, O, 1995)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19907 (18.42)18.7374
1990's6 (15.79)18.2507
2000's13 (34.21)29.6817
2010's11 (28.95)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Sakata, Y1
Sano, K1
Aoki, S1
Saitsu, H1
Takanashi, JI1
Wu, HC1
Dachet, F1
Ghoddoussi, F1
Bagla, S1
Fuerst, D1
Stanley, JA1
Galloway, MP1
Loeb, JA1
Oya, M1
Suzuki, H1
Anas, ARJ1
Oishi, K1
Ono, K1
Yamaguchi, S1
Eguchi, M1
Sawada, M1
Rychikhin, VM1
Sariev, AK1
Pomytkin, IA1
Tschampa, HJ1
Urbach, H1
Träber, F1
Sprinkart, AM1
Greschus, S1
Malter, MP1
Surges, R1
Gieseke, J1
Block, W1
Matias, M1
Silvestre, S1
Falcao, A1
Alves, G1
Ozisik, HI1
Sarac, K1
Ozcan, C1
Le Fur, Y1
Nicoli, F1
Guye, M1
Confort-Gouny, S1
Cozzone, PJ1
Kober, F1
Shao, XL1
Zhou, ZS1
Hong, W1
Lee, EM1
Park, GY1
Im, KC1
Kim, ST1
Woo, CW1
Chung, JH1
Kim, KS1
Kim, JS1
Shon, YM1
Kim, YI1
Kang, JK1
Motin, VG1
Udow, S1
Bunge, M1
Ryner, L1
Mhanni, AA1
Salman, MS1
Blusztajn, JK1
Mellott, TJ1
Ziyeh, S1
Thiel, T1
Spreer, J1
Klisch, J1
Schumacher, M1
Roshan-Milani, S1
Ferrigan, L1
Khoshnood, MJ1
Davies, CH1
Cobb, SR1
Hetherington, HP1
Kim, JH1
Pan, JW1
Spencer, DD1
Mueller, SG3
D Laxer, K1
Barakos, JA2
Cashdollar, N3
Flenniken, DL2
Vermathen, P2
Matson, GB2
Weiner, MW4
Briellmann, RS1
Wellard, RM1
Jackson, GD1
Laxer, KD2
Flügel, D1
McLean, MA3
Simister, RJ1
Duncan, JS3
Lopez, RC1
Schuff, N1
Meyerhoff, DJ1
Mueller, S1
Chao, L1
Sacrey, DT1
Laxer, K1
Hiremath, GK1
Najm, IM1
TOWER, DB2
McEACHERN, D2
CONE, WV1
Paggi, A1
Quattrini, A1
Ortenzi, A1
Cianci, F1
Silvestri, R1
Mancini, S1
Breiter, SN1
Arroyo, S1
Mathews, VP1
Lesser, RP1
Bryan, RN1
Barker, PB1
Richard, O1
Hevor, T1
Gadian, DG1
Kuzniecky, R1
Hetherington, H1
Pan, J1
Hugg, J1
Palmer, C1
Gilliam, F1
Faught, E1
Morawetz, R1
Holopainen, IE1
Valtonen, ME1
Komu, ME1
Sonninen, PH1
Manner, TE1
Lundbom, NM1
Sillanpää, ML1
Woermann, FG2
Barker, GJ2
Bartlett, PA1
Jope, RS1
Gu, X1
Laird, HE1
Hadjiconstantinou, M1
Neff, NH1
Olney, JW1
Collins, RC1
Sloviter, RS1
McGeer, PL1
McGeer, EG1
Sytiniskiĭ, IA1

Reviews

7 reviews available for choline and Aura

ArticleYear
Recent Highlights on Molecular Hybrids Potentially Useful in Central Nervous System Disorders.
    Mini reviews in medicinal chemistry, 2017, Volume: 17, Issue:6

    Topics: Analgesics; Central Nervous System Diseases; Choline; Donepezil; Epilepsy; gamma-Aminobutyric Acid;

2017
Neuroprotective actions of perinatal choline nutrition.
    Clinical chemistry and laboratory medicine, 2013, Mar-01, Volume: 51, Issue:3

    Topics: Animals; Brain; Choline; DNA; Epilepsy; Gene Expression Regulation; Hippocampus; Histones; Humans; M

2013
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
    Epilepsia, 2005, Volume: 46, Issue:5

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn

2005
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries;

2006
Magnetic resonance spectroscopy in animal models of epilepsy.
    Epilepsia, 2007, Volume: 48 Suppl 4

    Topics: Animals; Aspartic Acid; Brain; Carbon Isotopes; Choline; Creatine; Disease Models, Animal; Epilepsy;

2007
Neurotransmitter synthetic enzymes.
    Progress in neurobiology, 1973, Volume: 2, Issue:1

    Topics: Acetylcholine; Acetyltransferases; Adenylyl Cyclases; Aging; Aminobutyrates; Animals; Brain; Brain C

1973
[Clinical use of gamma-aminobutyric acid derivatives in experimental and clinical psychiatry and neurology (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1971, Volume: 71, Issue:2

    Topics: Aminobutyrates; Animals; Choline; Epilepsy; Humans; Hydroxybutyrates; Hypertension; Hypoxia; Mental

1971

Trials

3 trials available for choline and Aura

ArticleYear
Magnetisation transfer ratio of choline is reduced following epileptic seizures.
    NMR in biomedicine, 2006, Volume: 19, Issue:2

    Topics: Adult; Biomarkers; Brain; Choline; Epilepsy; Female; Humans; Magnetic Resonance Spectroscopy; Magnet

2006
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
    Magnetic resonance in medicine, 2000, Volume: 44, Issue:3

    Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; D

2000
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy.
    Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 2

    Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Dipeptides; Epilepsy

2001

Other Studies

28 other studies available for choline and Aura

ArticleYear
Neurochemistry evaluated by MR spectroscopy in a patient with SPTAN1-related developmental and epileptic encephalopathy.
    Brain & development, 2022, Volume: 44, Issue:6

    Topics: Choline; Epilepsy; Epilepsy, Generalized; Female; Glutamates; Glutamine; Humans; Infant; Magnetic Re

2022
Altered metabolomic-genomic signature: A potential noninvasive biomarker of epilepsy.
    Epilepsia, 2017, Volume: 58, Issue:9

    Topics: Adolescent; Biomarkers; Brain; Child; Child, Preschool; Choline; Creatine; Epilepsy; Female; Genetic

2017
LC-MS/MS imaging with thermal film-based laser microdissection.
    Analytical and bioanalytical chemistry, 2018, Volume: 410, Issue:2

    Topics: Acetylcholine; Animals; Choline; Chromatography, Liquid; Epilepsy; Female; gamma-Aminobutyric Acid;

2018
[Anticonvulsant effect of dicholine succinate on primary generalized epilepsy model in mice].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:3

    Topics: Animals; Anticonvulsants; Choline; Convulsants; Disease Models, Animal; Dose-Response Relationship,

2013
Proton magnetic resonance spectroscopy in focal cortical dysplasia at 3T.
    Seizure, 2015, Volume: 32

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Child, Preschool; Choline; Creatine; Drug Resistant E

2015
Single-voxel magnetic resonance spectroscopy of brain tissue adjacent to arachnoid cysts of epileptic patients.
    The neurologist, 2008, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Arachnoid Cysts; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Creatine; E

2008
Grid-free interactive and automated data processing for MR chemical shift imaging data.
    Magma (New York, N.Y.), 2010, Volume: 23, Issue:1

    Topics: Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Case-Control Studies; Choline; Creatine; Elect

2010
[Clinical application of proton magnetic resonance spectroscopy in children with idiopathic epilepsy].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:6

    Topics: Aspartic Acid; Child; Child, Preschool; Choline; Epilepsy; Female; Humans; Magnetic Resonance Imagin

2010
Changes in glucose metabolism and metabolites during the epileptogenic process in the lithium-pilocarpine model of epilepsy.
    Epilepsia, 2012, Volume: 53, Issue:5

    Topics: Animals; Aspartic Acid; Brain Mapping; Choline; Creatine; Disease Models, Animal; Epilepsy; Fluorode

2012
Acetylcholine precursor choline evokes NMDA-dependent epileptoid activity in rat hippocampal CA1 area.
    Bulletin of experimental biology and medicine, 2011, Volume: 152, Issue:1

    Topics: Aconitine; Action Potentials; Animals; CA1 Region, Hippocampal; Choline; Dizocilpine Maleate; Epilep

2011
Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease.
    Pediatric neurology, 2012, Volume: 47, Issue:4

    Topics: Anticonvulsants; Aspartic Acid; Brain Chemistry; Choline; Combined Modality Therapy; Creatine; DNA M

2012
Valproate-induced encephalopathy: assessment with MR imaging and 1H MR spectroscopy.
    Epilepsia, 2002, Volume: 43, Issue:9

    Topics: Adult; Anticonvulsants; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Epilepsy

2002
Regulation of epileptiform activity in hippocampus by nicotinic acetylcholine receptor activation.
    Epilepsy research, 2003, Volume: 56, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Action Potentials; Analysis of Variance; Animals; Bicu

2003
1H and 31P spectroscopic imaging of epilepsy: spectroscopic and histologic correlations.
    Epilepsia, 2004, Volume: 45 Suppl 4

    Topics: Adult; Amygdala; Aspartic Acid; Brain; Choline; Creatine; Epilepsy; Epilepsy, Temporal Lobe; Female;

2004
Identification of the epileptogenic lobe in neocortical epilepsy with proton MR spectroscopic imaging.
    Epilepsia, 2004, Volume: 45, Issue:12

    Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Choline; Creatine; Electroencephalography; Epilepsi

2004
Metabolic characteristics of cortical malformations causing epilepsy.
    Journal of neurology, 2005, Volume: 252, Issue:9

    Topics: Adolescent; Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Epilepsy; Humans; Image Proces

2005
Spectroscopic evidence of hippocampal abnormalities in neocortical epilepsy.
    European journal of neurology, 2006, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Epilepsy; Female; Functional Laterality; Hippoc

2006
Acetylcholine and neuronal activity; acetylcholine and cholines terase activity in the cerebrospinal fluids of patients with epilepsy.
    Canadian journal of research, 1949, Volume: 27, Issue:2

    Topics: Acetylcholine; Choline; Epilepsy; Humans

1949
Acetylcholine and neuronal activity in epilepsy.
    Transactions of the American Neurological Association, 1948, Volume: 73, Issue:73 Annual

    Topics: Acetylcholine; Choline; Epilepsy

1948
[Dementia syndromes and epilepsy].
    Minerva medica, 1984, Feb-18, Volume: 75, Issue:6

    Topics: Adult; Aged; Alzheimer Disease; Choline; Dementia; Electroencephalography; Epilepsy; Female; Humans;

1984
Proton MR spectroscopy in patients with seizure disorders.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine

1994
Methionine sulfoximine increases acetylcholine level in the rat brain: no relation with epileptogenesis.
    Neuroreport, 1995, Oct-23, Volume: 6, Issue:15

    Topics: Acetylcholine; Animals; Atropine; Brain; Choline; Epilepsy; Male; Methionine Sulfoximine; Physostigm

1995
N-acetylaspartate and epilepsy.
    Magnetic resonance imaging, 1995, Volume: 13, Issue:8

    Topics: Adult; Aspartic Acid; Brain Damage, Chronic; Brain Mapping; Child; Choline; Creatine; Dominance, Cer

1995
Proton spectroscopic imaging at 4.1 tesla in patients with malformations of cortical development and epilepsy.
    Neurology, 1997, Volume: 48, Issue:4

    Topics: Acetylation; Adolescent; Adult; Brain; Brain Neoplasms; Cerebral Cortex; Choline; Choristoma; Creati

1997
Proton spectroscopy in children with epilepsy and febrile convulsions.
    Pediatric neurology, 1998, Volume: 19, Issue:2

    Topics: Aspartic Acid; Child; Child, Preschool; Choline; Electroencephalography; Epilepsy; Hippocampus; Huma

1998
Seizures increase acetylcholine and choline concentrations in rat brain regions.
    Neurochemical research, 1991, Volume: 16, Issue:11

    Topics: Acetylcholine; Animals; Brain; Choline; Epilepsy; Kainic Acid; Lithium; Male; Pilocarpine; Rats; Rat

1991
Abnormalities in the central cholinergic transmitter system of the genetically epilepsy-prone rat.
    Life sciences, 1986, Sep-01, Volume: 39, Issue:9

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Brain Chemistry; Choline; Choline O-Acetyltransferase;

1986
Excitotoxic mechanisms of epileptic brain damage.
    Advances in neurology, 1986, Volume: 44

    Topics: Administration, Topical; Amygdala; Animals; Axons; Biomechanical Phenomena; Brain; Choline; Cholines

1986