choline has been researched along with Atherogenesis in 83 studies
Excerpt | Relevance | Reference |
---|---|---|
" Among the well-known con¬tributors to atherosclerosis are less common ones, such as trimethylamine oxide (TMAO)." | 8.31 | TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS. ( Lazar, M; Olma, A; Streb, W, 2023) |
"Recent evidence suggests that trimethylamine-N-oxide (TMAO), a metabolite of L-carnitine and choline, is linked to atherosclerosis and cardiovascular diseases." | 8.31 | Neither Trimethylamine-N-Oxide nor Trimethyllysine Is Associated with Atherosclerosis: A Cross-Sectional Study in Older Japanese Adults. ( Abe, T; Bhuiya, J; Isomura, M; Kobayashi, H; Nabika, T; Nagai, A; Notsu, Y; Okazaki, R; Sheikh, AM; Shibly, AZ; Yamaguchi, K; Yamasaki, M; Yano, S, 2023) |
"Microbial trimethylamine (TMA)-lyase activity promotes the development of atherosclerosis by generating of TMA, the precursor of TMA N-oxide (TMAO)." | 8.12 | Integrated metagenomics identifies a crucial role for trimethylamine-producing Lachnoclostridium in promoting atherosclerosis. ( Alolga, RN; Cai, YY; Gao, X; Huang, FQ; Lao, X; Li, J; Liu, B; Lu, Y; Qi, LW; Shang, J; Wang, Y; Yin, K; Zhou, X, 2022) |
"Trimethylamine-N-oxide (TMAO), a gut-microbiota-dependent metabolite after ingesting dietary choline, has been identified as a novel risk factor for atherosclerosis through inducing vascular inflammation." | 8.12 | Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1. ( Hong, Y; Ji, N; Luo, X; Ma, W; Nie, Z; Shan, J; Xue, J; Zhang, T; Zhang, Y; Zhou, S; Zhu, W, 2022) |
"Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis." | 8.02 | Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. ( Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y, 2021) |
"The aim of this study was to further investigate the relation between dietary choline and atherosclerosis in 2 atherogenic mouse models, the LDL receptor knockout (Ldlr-/-) and Apoe-/- mice." | 7.96 | Dietary Choline or Trimethylamine N-oxide Supplementation Does Not Influence Atherosclerosis Development in Ldlr-/- and Apoe-/- Male Mice. ( Aldana-Hernández, P; Curtis, JM; Field, CJ; Jacobs, RL; Leonard, KA; Zhao, YY, 2020) |
"The objective of this study was to determine whether ectopic hepatic PEMT expression or choline supplementation would promote atherosclerosis in Pemt-/-/Ldlr-/- mice." | 7.88 | Hepatic Expression of PEMT, but Not Dietary Choline Supplementation, Reverses the Protection against Atherosclerosis in Pemt-/-/Ldlr-/- Mice. ( Al Rajabi, A; Curtis, JM; Field, CJ; Jacobs, RL; Ju, T; Leonard, KA; Mi, S; Nelson, R; Thiesen, A; van der Veen, JN; Willing, BP; Zia, Y, 2018) |
"Trimethylamine (TMA) N-oxide (TMAO), a gut-microbiota-dependent metabolite, both enhances atherosclerosis in animal models and is associated with cardiovascular risks in clinical studies." | 7.81 | Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis. ( Buffa, JA; Culley, MK; DiDonato, AJ; DiDonato, JA; Fu, X; Gu, X; Hazen, JE; Hazen, SL; Huang, Y; Krajcik, D; Levison, BS; Lusis, AJ; Org, E; Roberts, AB; Wang, Z; Zamanian-Daryoush, M; Zhu, W, 2015) |
" We demonstrate here that metabolism by intestinal microbiota of dietary L-carnitine, a trimethylamine abundant in red meat, also produces TMAO and accelerates atherosclerosis in mice." | 7.79 | Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. ( Britt, EB; Brown, JM; Buffa, JA; Bushman, FD; Chen, J; DiDonato, JA; Fu, X; Hazen, SL; Koeth, RA; Krauss, RM; Levison, BS; Lewis, JD; Li, H; Li, L; Lusis, AJ; Org, E; Sheehy, BT; Smith, JD; Tang, WH; Wang, Z; Warrier, M; Wu, GD; Wu, Y, 2013) |
"Circulating trimethylamine-N-oxide (TMAO) levels are strongly associated with atherosclerosis." | 7.79 | Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. ( Allayee, H; Bennett, BJ; Crooke, R; de Aguiar Vallim, TQ; Edwards, PA; Graham, M; Gregory, J; Hazen, SL; Lee, R; Lusis, AJ; Meng, Y; Shih, DM; Wang, Z, 2013) |
"Low dietary intake of the essential nutrient choline and its metabolite betaine may increase atherogenesis both through effects on homocysteine methylation pathways as well as through choline's antioxidants properties." | 7.74 | Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. ( Bidulescu, A; Chambless, LE; Heiss, G; Siega-Riz, AM; Zeisel, SH, 2007) |
"Phosphorylcholine (PC) is an important pro-inflammatory damage-associated molecular pattern." | 5.62 | Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases. ( Bergman, A; Dahlbom, I; de Jong, RCM; de Vries, MR; Ewing, MM; Frostegård, J; Jukema, JW; Karabina, SAP; Karper, JC; Kuiper, J; MacArthur, MR; Mitchell, JR; Ninio, E; Nordzell, M; Peters, EAB; Pettersson, K; Quax, PHA; Sexton, D, 2021) |
" Trimethylamine N-oxide (TMAO) is produced from the metabolism of dietary choline and L-carnitine by intestinal microbiota, and many studies have shown that this important product inhibits cholesterol metabolism, induces platelet aggregation and thrombosis, and promotes atherosclerosis." | 5.41 | The gut microbial metabolite trimethylamine N-oxide and cardiovascular diseases. ( Cai, XC; Han, HX; He, M; Kang, XX; Liu, X; Lv, EH; Tian, JQ; Wang, YT; Wen, PB; Xiao, L; Zhang, MY; Zhen, J; Zhou, Z, 2023) |
"Recent evidence suggests that trimethylamine-N-oxide (TMAO), a metabolite of L-carnitine and choline, is linked to atherosclerosis and cardiovascular diseases." | 4.31 | Neither Trimethylamine-N-Oxide nor Trimethyllysine Is Associated with Atherosclerosis: A Cross-Sectional Study in Older Japanese Adults. ( Abe, T; Bhuiya, J; Isomura, M; Kobayashi, H; Nabika, T; Nagai, A; Notsu, Y; Okazaki, R; Sheikh, AM; Shibly, AZ; Yamaguchi, K; Yamasaki, M; Yano, S, 2023) |
" Among the well-known con¬tributors to atherosclerosis are less common ones, such as trimethylamine oxide (TMAO)." | 4.31 | TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS. ( Lazar, M; Olma, A; Streb, W, 2023) |
" Therefore, PSRC1 overexpression and reduced choline consumption may further alleviate atherosclerosis." | 4.12 | Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE ( Chen, M; Chen, P; Guo, Z; Liu, D; Luo, T; Ou, C, 2022) |
"Trimethylamine-N-oxide (TMAO), a gut-microbiota-dependent metabolite after ingesting dietary choline, has been identified as a novel risk factor for atherosclerosis through inducing vascular inflammation." | 4.12 | Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1. ( Hong, Y; Ji, N; Luo, X; Ma, W; Nie, Z; Shan, J; Xue, J; Zhang, T; Zhang, Y; Zhou, S; Zhu, W, 2022) |
"Microbial trimethylamine (TMA)-lyase activity promotes the development of atherosclerosis by generating of TMA, the precursor of TMA N-oxide (TMAO)." | 4.12 | Integrated metagenomics identifies a crucial role for trimethylamine-producing Lachnoclostridium in promoting atherosclerosis. ( Alolga, RN; Cai, YY; Gao, X; Huang, FQ; Lao, X; Li, J; Liu, B; Lu, Y; Qi, LW; Shang, J; Wang, Y; Yin, K; Zhou, X, 2022) |
"Trimethylamine-N-oxide (TMAO), a gut-microbiota-dependent metabolite generated from its dietary precursors such as choline, has been identified as an independent risk factor for atherosclerosis." | 4.02 | Metformin alleviates choline diet-induced TMAO elevation in C57BL/6J mice by influencing gut-microbiota composition and functionality. ( Du, Y; Hong, B; Li, X; Su, C; Wang, L; Yang, Y; Zhang, X, 2021) |
"Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis." | 4.02 | Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. ( Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y, 2021) |
"The aim of this study was to further investigate the relation between dietary choline and atherosclerosis in 2 atherogenic mouse models, the LDL receptor knockout (Ldlr-/-) and Apoe-/- mice." | 3.96 | Dietary Choline or Trimethylamine N-oxide Supplementation Does Not Influence Atherosclerosis Development in Ldlr-/- and Apoe-/- Male Mice. ( Aldana-Hernández, P; Curtis, JM; Field, CJ; Jacobs, RL; Leonard, KA; Zhao, YY, 2020) |
" Furthermore, unlike chronic dietary choline, TML supplementation in mice failed to elevate plasma TMAO or heighten thrombosis potential in vivo." | 3.88 | Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. ( Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y, 2018) |
"The objective of this study was to determine whether ectopic hepatic PEMT expression or choline supplementation would promote atherosclerosis in Pemt-/-/Ldlr-/- mice." | 3.88 | Hepatic Expression of PEMT, but Not Dietary Choline Supplementation, Reverses the Protection against Atherosclerosis in Pemt-/-/Ldlr-/- Mice. ( Al Rajabi, A; Curtis, JM; Field, CJ; Jacobs, RL; Ju, T; Leonard, KA; Mi, S; Nelson, R; Thiesen, A; van der Veen, JN; Willing, BP; Zia, Y, 2018) |
"The choline-derived metabolite trimethylamine N-oxide (TMAO) has been demonstrated to contribute to atherosclerosis and is associated with coronary artery disease risk." | 3.83 | Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB. ( Hazen, SL; Lusis, AJ; Meng, Y; Qi, H; Seldin, MM; Shih, DM; Wang, Z; Zhu, W, 2016) |
" Here we test the hypothesis that gut microbial transplantation can transmit choline diet-induced TMAO production and atherosclerosis susceptibility." | 3.81 | Transmission of atherosclerosis susceptibility with gut microbial transplantation. ( Bennett, BJ; Buffa, JA; DiDonato, JA; Gregory, JC; Hazen, SL; Levison, BS; Li, L; Lusis, AJ; Org, E; Wagner, MA; Wang, Z; Zhu, W, 2015) |
"Trimethylamine (TMA) N-oxide (TMAO), a gut-microbiota-dependent metabolite, both enhances atherosclerosis in animal models and is associated with cardiovascular risks in clinical studies." | 3.81 | Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis. ( Buffa, JA; Culley, MK; DiDonato, AJ; DiDonato, JA; Fu, X; Gu, X; Hazen, JE; Hazen, SL; Huang, Y; Krajcik, D; Levison, BS; Lusis, AJ; Org, E; Roberts, AB; Wang, Z; Zamanian-Daryoush, M; Zhu, W, 2015) |
" We demonstrate here that metabolism by intestinal microbiota of dietary L-carnitine, a trimethylamine abundant in red meat, also produces TMAO and accelerates atherosclerosis in mice." | 3.79 | Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. ( Britt, EB; Brown, JM; Buffa, JA; Bushman, FD; Chen, J; DiDonato, JA; Fu, X; Hazen, SL; Koeth, RA; Krauss, RM; Levison, BS; Lewis, JD; Li, H; Li, L; Lusis, AJ; Org, E; Sheehy, BT; Smith, JD; Tang, WH; Wang, Z; Warrier, M; Wu, GD; Wu, Y, 2013) |
"Circulating trimethylamine-N-oxide (TMAO) levels are strongly associated with atherosclerosis." | 3.79 | Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. ( Allayee, H; Bennett, BJ; Crooke, R; de Aguiar Vallim, TQ; Edwards, PA; Graham, M; Gregory, J; Hazen, SL; Lee, R; Lusis, AJ; Meng, Y; Shih, DM; Wang, Z, 2013) |
"The purpose of this study was to explore the feasibility of (11)C-choline in the assessment of the degree of inflammation in atherosclerotic plaques." | 3.76 | Uptake of 11C-choline in mouse atherosclerotic plaques. ( Hellberg, S; Knuuti, J; Laine, VJ; Laitinen, IE; Luoto, P; Marjamäki, PM; Någren, K; Roivainen, A; Silvola, JM; Ylä-Herttuala, S, 2010) |
"Low dietary intake of the essential nutrient choline and its metabolite betaine may increase atherogenesis both through effects on homocysteine methylation pathways as well as through choline's antioxidants properties." | 3.74 | Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. ( Bidulescu, A; Chambless, LE; Heiss, G; Siega-Riz, AM; Zeisel, SH, 2007) |
"Phenylacetylglutamine, for example, was recently shown to promote adverse cardiovascular phenotypes in the host via interaction with multiple ARs (adrenergic receptors)-a class of key receptors that regulate cardiovascular homeostasis." | 2.66 | Gut Microbiota and Cardiovascular Disease. ( Hazen, SL; Weeks, TL; Witkowski, M, 2020) |
"Atherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression." | 1.72 | TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis. ( Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J, 2022) |
"Phosphorylcholine (PC) is an important pro-inflammatory damage-associated molecular pattern." | 1.62 | Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases. ( Bergman, A; Dahlbom, I; de Jong, RCM; de Vries, MR; Ewing, MM; Frostegård, J; Jukema, JW; Karabina, SAP; Karper, JC; Kuiper, J; MacArthur, MR; Mitchell, JR; Ninio, E; Nordzell, M; Peters, EAB; Pettersson, K; Quax, PHA; Sexton, D, 2021) |
"The (18)F-FMCH uptake in atherosclerotic plaques was further compared with macrophage infiltration and the plasma levels of cytokines and metabolic markers." | 1.43 | Type 2 diabetes enhances arterial uptake of choline in atherosclerotic mice: an imaging study with positron emission tomography tracer ¹⁸F-fluoromethylcholine. ( Hellberg, S; Jauhiainen, M; Kiugel, M; Knuuti, J; Liljenbäck, H; Metsälä, O; Metso, J; Nuutila, P; Roivainen, A; Saraste, A; Saukko, P; Silvola, JM; Viljanen, T; Ylä-Herttuala, S, 2016) |
"Atherosclerosis is a multifactorial and progressive disease commonly correlated with a high fat diet." | 1.40 | Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy. ( Guo, J; Li, J; Li, X; Liu, Y; Wang, L; Wu, T; Yang, Y; Yuan, F; Zhang, Q; Zheng, L, 2014) |
"11C-choline uptake was found in 95% of patients, calcification in 94% throughout all vessel segments." | 1.35 | Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT. ( Ikeda, M; Ishigaki, T; Kato, K; Kies, P; Naganawa, S; Schäfers, M; Schober, O; Stegger, L, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 26 (31.33) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (3.61) | 29.6817 |
2010's | 31 (37.35) | 24.3611 |
2020's | 23 (27.71) | 2.80 |
Authors | Studies |
---|---|
Cai, YY | 1 |
Huang, FQ | 1 |
Lao, X | 1 |
Lu, Y | 1 |
Gao, X | 1 |
Alolga, RN | 1 |
Yin, K | 1 |
Zhou, X | 1 |
Wang, Y | 4 |
Liu, B | 1 |
Shang, J | 1 |
Qi, LW | 1 |
Li, J | 2 |
Luo, T | 1 |
Liu, D | 1 |
Guo, Z | 2 |
Chen, P | 1 |
Ou, C | 1 |
Chen, M | 1 |
Chen, CY | 1 |
Leu, HB | 1 |
Wang, SC | 1 |
Tsai, SH | 1 |
Chou, RH | 1 |
Lu, YW | 1 |
Tsai, YL | 1 |
Kuo, CS | 1 |
Huang, PH | 1 |
Chen, JW | 1 |
Lin, SJ | 1 |
Zhu, X | 1 |
Zhao, L | 1 |
Hu, X | 1 |
Zhu, Y | 1 |
Yang, X | 1 |
Ma, SR | 1 |
Tong, Q | 1 |
Lin, Y | 1 |
Pan, LB | 1 |
Fu, J | 1 |
Peng, R | 1 |
Zhang, XF | 1 |
Zhao, ZX | 1 |
Li, Y | 1 |
Yu, JB | 1 |
Cong, L | 1 |
Han, P | 1 |
Zhang, ZW | 1 |
Yu, H | 1 |
Jiang, JD | 1 |
Iglesias-Carres, L | 1 |
Racine, KC | 1 |
Neilson, AP | 1 |
Xiong, X | 1 |
Zhou, J | 1 |
Fu, Q | 1 |
Xu, X | 1 |
Wei, S | 1 |
Yang, S | 1 |
Chen, B | 1 |
Zhou, S | 1 |
Xue, J | 1 |
Shan, J | 1 |
Hong, Y | 1 |
Zhu, W | 5 |
Nie, Z | 1 |
Zhang, Y | 2 |
Ji, N | 1 |
Luo, X | 1 |
Zhang, T | 1 |
Ma, W | 1 |
Díez-Ricote, L | 1 |
Ruiz-Valderrey, P | 1 |
Micó, V | 1 |
Blanco, R | 1 |
Tomé-Carneiro, J | 1 |
Dávalos, A | 1 |
Ordovás, JM | 1 |
Daimiel, L | 1 |
Liu, C | 1 |
Li, Z | 1 |
Song, Z | 1 |
Fan, X | 1 |
Shao, H | 1 |
Schönke, M | 1 |
Boon, MR | 1 |
Rensen, PCN | 1 |
Bhuiya, J | 1 |
Notsu, Y | 1 |
Kobayashi, H | 1 |
Shibly, AZ | 1 |
Sheikh, AM | 1 |
Okazaki, R | 1 |
Yamaguchi, K | 1 |
Nagai, A | 1 |
Nabika, T | 1 |
Abe, T | 1 |
Yamasaki, M | 1 |
Isomura, M | 1 |
Yano, S | 1 |
Zhen, J | 1 |
Zhou, Z | 1 |
He, M | 1 |
Han, HX | 1 |
Lv, EH | 1 |
Wen, PB | 1 |
Liu, X | 1 |
Wang, YT | 1 |
Cai, XC | 1 |
Tian, JQ | 1 |
Zhang, MY | 1 |
Xiao, L | 1 |
Kang, XX | 1 |
Olma, A | 1 |
Streb, W | 1 |
Lazar, M | 1 |
Mu, HN | 1 |
Zhao, XH | 1 |
Zhang, RR | 1 |
Li, ZY | 1 |
Yang, RY | 1 |
Wang, SM | 1 |
Li, HX | 1 |
Chen, WX | 1 |
Dong, J | 1 |
Oktaviono, YH | 1 |
Dyah Lamara, A | 1 |
Saputra, PBT | 1 |
Arnindita, JN | 1 |
Pasahari, D | 1 |
Saputra, ME | 1 |
Suasti, NMA | 1 |
He, Z | 1 |
Zhu, H | 1 |
Liu, J | 1 |
Kwek, E | 1 |
Ma, KY | 1 |
Chen, ZY | 1 |
Aldana-Hernández, P | 1 |
Leonard, KA | 2 |
Zhao, YY | 1 |
Curtis, JM | 2 |
Field, CJ | 2 |
Jacobs, RL | 2 |
Montandon, SA | 1 |
Somm, E | 1 |
Loizides-Mangold, U | 1 |
de Vito, C | 1 |
Dibner, C | 1 |
Jornayvaz, FR | 1 |
Busnelli, M | 1 |
Manzini, S | 1 |
Chiesa, G | 1 |
Koay, YC | 1 |
Chen, YC | 1 |
Wali, JA | 1 |
Luk, AWS | 1 |
Li, M | 1 |
Doma, H | 1 |
Reimark, R | 1 |
Zaldivia, MTK | 1 |
Habtom, HT | 1 |
Franks, AE | 1 |
Fusco-Allison, G | 1 |
Yang, J | 1 |
Holmes, A | 1 |
Simpson, SJ | 1 |
Peter, K | 1 |
O'Sullivan, JF | 1 |
Witkowski, M | 1 |
Weeks, TL | 1 |
Hazen, SL | 10 |
de Vries, MR | 1 |
Ewing, MM | 1 |
de Jong, RCM | 1 |
MacArthur, MR | 1 |
Karper, JC | 1 |
Peters, EAB | 1 |
Nordzell, M | 1 |
Karabina, SAP | 1 |
Sexton, D | 1 |
Dahlbom, I | 1 |
Bergman, A | 1 |
Mitchell, JR | 1 |
Frostegård, J | 1 |
Kuiper, J | 1 |
Ninio, E | 1 |
Jukema, JW | 1 |
Pettersson, K | 1 |
Quax, PHA | 1 |
Li, X | 3 |
Su, C | 2 |
Jiang, Z | 1 |
Yang, Y | 3 |
Yang, M | 1 |
Zhang, X | 2 |
Du, Y | 2 |
Zhang, J | 1 |
Wang, L | 3 |
Jiang, J | 1 |
Hong, B | 2 |
Aguilar-Ramirez, D | 1 |
Alegre-Díaz, J | 1 |
Herrington, WG | 1 |
Staplin, N | 1 |
Ramirez-Reyes, R | 1 |
Gnatiuc, L | 1 |
Hill, M | 1 |
Romer, F | 1 |
Torres, J | 1 |
Trichia, E | 1 |
Wade, R | 1 |
Collins, R | 1 |
Emberson, JR | 1 |
Kuri-Morales, P | 1 |
Tapia-Conyer, R | 1 |
Li, XS | 1 |
Wang, Z | 8 |
Cajka, T | 1 |
Buffa, JA | 4 |
Nemet, I | 1 |
Hurd, AG | 1 |
Gu, X | 2 |
Skye, SM | 1 |
Roberts, AB | 2 |
Wu, Y | 3 |
Li, L | 3 |
Shahen, CJ | 1 |
Wagner, MA | 2 |
Hartiala, JA | 1 |
Kerby, RL | 1 |
Romano, KA | 1 |
Han, Y | 1 |
Obeid, S | 1 |
Lüscher, TF | 2 |
Allayee, H | 4 |
Rey, FE | 1 |
DiDonato, JA | 5 |
Fiehn, O | 1 |
Tang, WHW | 1 |
Lindskog Jonsson, A | 1 |
Caesar, R | 1 |
Akrami, R | 1 |
Reinhardt, C | 1 |
Fåk Hållenius, F | 1 |
Borén, J | 1 |
Bäckhed, F | 2 |
Shan, Z | 1 |
Clish, CB | 1 |
Hua, S | 1 |
Scott, JM | 1 |
Hanna, DB | 1 |
Burk, RD | 1 |
Haberlen, SA | 1 |
Shah, SJ | 1 |
Margolick, JB | 1 |
Sears, CL | 1 |
Post, WS | 1 |
Landay, AL | 1 |
Lazar, JM | 1 |
Hodis, HN | 1 |
Anastos, K | 1 |
Kaplan, RC | 1 |
Qi, Q | 1 |
Qiu, L | 1 |
Tao, X | 1 |
Xiong, H | 1 |
Yu, J | 1 |
Wei, H | 1 |
Zia, Y | 1 |
Al Rajabi, A | 1 |
Mi, S | 1 |
Ju, T | 1 |
Nelson, R | 1 |
Thiesen, A | 1 |
Willing, BP | 1 |
van der Veen, JN | 1 |
Gautam, A | 1 |
Paudel, YN | 1 |
Abidin, S | 1 |
Bhandari, U | 1 |
Coffey, AR | 1 |
Kanke, M | 1 |
Smallwood, TL | 1 |
Albright, J | 1 |
Pitman, W | 1 |
Gharaibeh, RZ | 1 |
Hua, K | 1 |
Gertz, E | 1 |
Biddinger, SB | 1 |
Temel, RE | 1 |
Pomp, D | 1 |
Sethupathy, P | 1 |
Bennett, BJ | 4 |
Joris, BR | 1 |
Gloor, GB | 1 |
Sinha, A | 1 |
Ma, Y | 1 |
Scherzer, R | 1 |
Rahalkar, S | 1 |
Neilan, BD | 1 |
Crane, H | 1 |
Drozd, D | 1 |
Martin, J | 1 |
Deeks, SG | 1 |
Hunt, P | 1 |
Hsue, PY | 1 |
Shih, DM | 3 |
Schugar, RC | 1 |
Meng, Y | 3 |
Jia, X | 1 |
Miikeda, A | 1 |
Zieger, M | 1 |
Lee, R | 2 |
Graham, M | 2 |
Cantor, RM | 1 |
Mueller, C | 1 |
Brown, JM | 2 |
Lusis, AJ | 7 |
Koeth, RA | 1 |
Levison, BS | 4 |
Org, E | 3 |
Sheehy, BT | 1 |
Britt, EB | 2 |
Fu, X | 3 |
Smith, JD | 2 |
Chen, J | 1 |
Li, H | 1 |
Wu, GD | 1 |
Lewis, JD | 1 |
Warrier, M | 1 |
Krauss, RM | 1 |
Tang, WH | 3 |
Bushman, FD | 1 |
Liu, Y | 1 |
Zheng, L | 1 |
Wu, T | 1 |
Zhang, Q | 1 |
Yuan, F | 1 |
Guo, J | 1 |
Gregory, JC | 1 |
Drosos, I | 1 |
Tavridou, A | 1 |
Kolios, G | 1 |
Berge, RK | 2 |
Ramsvik, MS | 1 |
Bohov, P | 1 |
Svardal, A | 2 |
Nordrehaug, JE | 1 |
Rostrup, E | 1 |
Bruheim, I | 1 |
Bjørndal, B | 1 |
Jonsson, AL | 1 |
Huang, Y | 1 |
Zamanian-Daryoush, M | 1 |
Culley, MK | 1 |
DiDonato, AJ | 1 |
Hazen, JE | 1 |
Krajcik, D | 1 |
Nunes-Alves, C | 1 |
Hellberg, S | 2 |
Silvola, JM | 2 |
Kiugel, M | 1 |
Liljenbäck, H | 1 |
Metsälä, O | 1 |
Viljanen, T | 1 |
Metso, J | 1 |
Jauhiainen, M | 1 |
Saukko, P | 1 |
Nuutila, P | 1 |
Ylä-Herttuala, S | 2 |
Knuuti, J | 2 |
Roivainen, A | 2 |
Saraste, A | 1 |
Seldin, MM | 1 |
Qi, H | 1 |
Trøseid, M | 1 |
Hov, JR | 1 |
Nestvold, TK | 1 |
Thoresen, H | 1 |
Lappegård, KT | 1 |
Petriello, MC | 1 |
Hoffman, JB | 1 |
Sunkara, M | 1 |
Wahlang, B | 1 |
Perkins, JT | 1 |
Morris, AJ | 1 |
Hennig, B | 1 |
STEINER, A | 1 |
MORRISON, LM | 2 |
ROSSI, A | 2 |
Kato, K | 1 |
Schober, O | 1 |
Ikeda, M | 1 |
Schäfers, M | 1 |
Ishigaki, T | 1 |
Kies, P | 1 |
Naganawa, S | 1 |
Stegger, L | 1 |
Cheng, KK | 1 |
Benson, GM | 1 |
Grimsditch, DC | 1 |
Reid, DG | 1 |
Connor, SC | 1 |
Griffin, JL | 1 |
Laitinen, IE | 1 |
Luoto, P | 1 |
Någren, K | 1 |
Marjamäki, PM | 1 |
Laine, VJ | 1 |
Rak, K | 1 |
Rader, DJ | 1 |
Klipfell, E | 1 |
Koeth, R | 1 |
Dugar, B | 1 |
Feldstein, AE | 1 |
Chung, YM | 1 |
Schauer, P | 1 |
Getz, GS | 1 |
Reardon, CA | 1 |
de Aguiar Vallim, TQ | 1 |
Gregory, J | 1 |
Crooke, R | 1 |
Edwards, PA | 1 |
FRANCO, A | 1 |
GONCALVES, A | 1 |
DUFF, GL | 1 |
MEISSNER, GF | 1 |
GOLDBLOOM, AA | 1 |
EIBER, HB | 1 |
BOYD, LJ | 1 |
PILGERAM, LO | 1 |
GREENBERG, DM | 1 |
KRITCHEVSKY, D | 1 |
MOYER, AW | 1 |
TESAR, WC | 1 |
LOGAN, JB | 1 |
MCCANDLESS, RF | 1 |
DAVIES, MC | 1 |
ANISIMOV, VE | 3 |
NISHIDA, T | 1 |
TAKENAKA, F | 2 |
KUMMEROW, FA | 1 |
ZAITSEV, VM | 1 |
WANG, C | 1 |
FAZIO, B | 1 |
BALESTRERI, R | 1 |
MEARDI, G | 1 |
TAVERNA, PL | 1 |
AIRO, R | 1 |
LUKOMSKII, PE | 1 |
MILLOT, J | 1 |
NIKKILA, EA | 1 |
OLLILA, O | 1 |
FIRSTBROOK, JB | 1 |
STAMLER, J | 2 |
BOLENE, C | 2 |
HARRIS, R | 2 |
KATZ, LN | 2 |
CAPRETTI, G | 1 |
PAGLIA, G | 1 |
POLLACK, OJ | 1 |
MOSES, C | 1 |
LONGABAUGH, GM | 1 |
Matter, CM | 1 |
Wyss, MT | 1 |
Meier, P | 1 |
Späth, N | 1 |
von Lukowicz, T | 1 |
Lohmann, C | 1 |
Weber, B | 1 |
Ramirez de Molina, A | 1 |
Lacal, JC | 1 |
Ametamey, SM | 1 |
von Schulthess, GK | 1 |
Kaufmann, PA | 1 |
Buck, A | 1 |
Bidulescu, A | 1 |
Chambless, LE | 1 |
Siega-Riz, AM | 1 |
Zeisel, SH | 1 |
Heiss, G | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
"Plant-Based Meat vs Animal Red Meat: a Randomized Cross-over Trial"[NCT04510324] | 41 participants (Actual) | Interventional | 2020-11-01 | Completed | |||
Impact of Facilitated Vegan Diet on Cardiometabolic Endpoints and Trimethylamine N-oxide[NCT05071196] | 70 participants (Anticipated) | Interventional | 2022-01-01 | Active, not recruiting | |||
Impact of Diet and Gut Microbiota on Trimethylamine-N-oxide Production and Fate in Humans[NCT02558673] | 40 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)[NCT02016430] | 150 participants (Anticipated) | Interventional | 2014-04-04 | Recruiting | |||
A Dietary Intervention With Functional Foods Reduce Metabolic Endotoxemia and Attenuates Biochemical Abnormalities in Subjects With Type 2 Diabetes by Modifying the Gut Microbiota.[NCT03421301] | 81 participants (Actual) | Interventional | 2014-08-07 | Completed | |||
Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.[NCT05795946] | 45 participants (Anticipated) | Interventional | 2023-04-15 | Recruiting | |||
Molecular Imaging of Plaque Vulnerability Using 18F-choline PET-MRI in Carotid Artery Atherosclerosis Patients[NCT02640313] | Phase 3 | 14 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | ||
Low Fat Vegan Diet or American Heart Association Diet, Impact on Biomarkers of Inflammation, Oxidative Stress and Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol: A Four Week Randomized Trial[NCT01817491] | 60 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
Effect of Choline Source and Gut Microbiota Composition on Trimethylamine-N-oxide Response in Humans[NCT04255368] | 44 participants (Actual) | Interventional | 2017-11-09 | Completed | |||
Effects of Choline Supplementation on Fetal Growth in Gestational Diabetes Mellitus[NCT04302168] | 60 participants (Anticipated) | Interventional | 2020-04-01 | Recruiting | |||
Analysis of MicroBial Metabolites After Eating Refined Food[NCT04308473] | 46 participants (Actual) | Interventional | 2020-09-01 | Active, not recruiting | |||
Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans (EGGS)[NCT03039023] | 86 participants (Actual) | Interventional | 2016-09-02 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
PAQ self reported questions based on activity level from 1 (low activity) to 5 (high activity), overall PAQ score is a mean of the questions. (NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | units on a scale (Mean) |
---|---|
Reduced Fat Vegan Diet | 0.22 |
American Heart Association Diet | -0.16 |
Body mass index z-scores, also called BMI standard deviation (s.d.) scores, are measures of relative weight adjusted for child age and sex. Given a child's age, sex, BMI, and an appropriate reference standard, a BMI z-score (or its equivalent BMI-for-age percentile) can be determined. Negative BMI z-scores indicate a BMI that is lower than the population mean, while positive BMI scores indicate a value that is higher than the population mean. A decrease in the BMI z-score over time indicate a lowering of the BMI. Z-scores of 1.03 and 1.64 correspond to the 85th and 95th percentiles of BMI-for-age, which are the definitions of overweight and obesity in children. (NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | Z Score (Mean) |
---|---|
Reduced Fat Vegan Diet | -0.14 |
American Heart Association Diet | -0.03 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | Z score (Mean) |
---|---|
PB/AHA | -0.13 |
PAQ self reported questions based on activity level from 1 (low activity) to 5 (high activity), overall PAQ score is a mean of the questions. (NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | units on a scale (Mean) |
---|---|
PB/AHA | 0.39 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | mm Hg (Mean) | |||
---|---|---|---|---|
Children Systolic BP | Parents Systolic BP | Children Diastolic BP | Parent Diastolic BP | |
American Heart Association Diet | -5.14 | -3.14 | -4.36 | -6.64 |
Reduced Fat Vegan Diet | -6.43 | -7.96 | -2.61 | -3.46 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | BMI percentile (Mean) | |
---|---|---|
Children | Parents | |
American Heart Association Diet | -0.08 | -0.73 |
Reduced Fat Vegan Diet | -1.12 | -1.29 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | cm (Mean) | |||
---|---|---|---|---|
Children Waist Circumference | Parents Waist Circumference | Children Midarm Circumference | Parents Midarm Circumference | |
American Heart Association Diet | -2.96 | -0.49 | -1.14 | 0.35 |
Reduced Fat Vegan Diet | -1.53 | -1.94 | -2.02 | -1.32 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | mg/dL (Mean) | |
---|---|---|
Children | Parent | |
American Heart Association Diet | -.64 | -5.43 |
Reduced Fat Vegan Diet | 0.93 | 4.93 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | percentage (Mean) | |
---|---|---|
Children | Parent | |
American Heart Association Diet | 0.21 | 0.14 |
Reduced Fat Vegan Diet | 0.17 | -0.16 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | mg/L (Mean) | |
---|---|---|
Children | Parent | |
American Heart Association Diet | 2.78 | 0.21 |
Reduced Fat Vegan Diet | -2.09 | -0.24 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | pg/ml (Mean) | |
---|---|---|
Children | Parent | |
American Heart Association Diet | -0.19 | -0.19 |
Reduced Fat Vegan Diet | -0.17 | 0.16 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | uU/ml (Mean) | |
---|---|---|
Children | Parents | |
American Heart Association Diet | 3.16 | -3.15 |
Reduced Fat Vegan Diet | -5.42 | -3.11 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | mg/dL (Mean) | |||||||
---|---|---|---|---|---|---|---|---|
total cholesterol children | triglycerides children | high-density lipoprotein cholesterol children | low-density lipoprotein cholesterol children | total cholesterol parents | triglycerides parents | high-density lipoprotein cholesterol parents | low-density lipoprotein cholesterol parents | |
American Heart Association Diet | -16.50 | -13.14 | -2.93 | -11.00 | -7.14 | 16.86 | 16.86 | -5.50 |
Reduced Fat Vegan Diet | -22.50 | -25.50 | -5.93 | -13.14 | -33.79 | 6.21 | -8.14 | -27.00 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | U/L (Mean) | |||
---|---|---|---|---|
alanine aminotransferase (ALT) children | aspartate aminotransferase (AST) children | alanine aminotransferase (ALT) parents | aspartate aminotransferase (AST) parents | |
American Heart Association Diet | -1.14 | 0.00 | 4.57 | 4.43 |
Reduced Fat Vegan Diet | 0.79 | 2.79 | 0.86 | 0.14 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | pmol/L (Mean) | |
---|---|---|
Children | Parent | |
American Heart Association Diet | -69.23 | 1.78 |
Reduced Fat Vegan Diet | -75.34 | 16.91 |
(NCT01817491)
Timeframe: baseline, 4 weeks
Intervention | kg (Mean) | |
---|---|---|
Children | Parents | |
American Heart Association Diet | -1.55 | -2.01 |
Reduced Fat Vegan Diet | -3.05 | -3.64 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | ratio (Mean) | |||
---|---|---|---|---|
Children adj mean ratio systolic BP | Children adj mean ratio diastolic BP | parents adj mean ratio systolic BP | parents adj mean ratio diastolic BP | |
PB/AHA | 1.87 | 1.01 | 0.97 | 1.03 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | percentile (Mean) | |
---|---|---|
Children Change in BMI | Parents Change in BMI | |
PB/AHA | -1.17 | -0.69 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | cm (Mean) | |||
---|---|---|---|---|
children waist circumference | parents waist circumference | children arm circumference | parents arm circumference | |
PB/AHA | 1.32 | -1.14 | -1.25 | -1.68 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | kg (Mean) | |
---|---|---|
Children Weight | Parents Weight | |
PB/AHA | -1.71 | -1.95 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | mg/dL (Mean) | |||||||
---|---|---|---|---|---|---|---|---|
CHOL children | TRIG children | HDL children | LDL children | CHOL parents | TRIG parents | HDL parents | LDL parents | |
PB/AHA | -10.34 | 1.01 | 0.17 | 0.95 | -27.29 | 0.95 | 0.94 | -21.92 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | ratio (Mean) | |
---|---|---|
Children | Parents | |
PB/AHA | 1.01 | 1.06 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | ratio (Mean) | |
---|---|---|
Children | Parents | |
PB/AHA | 0.99 | 0.96 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | ratio (Mean) | |
---|---|---|
Children | Parents | |
PB/AHA | 0.46 | 0.68 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | ratio (Mean) | |
---|---|---|
Children | Parents | |
PB/AHA | 0.26 | 1.14 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | ratio (Mean) | |
---|---|---|
Children | Parents | |
PB/AHA | 0.7 | 0.87 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | ratio (Mean) | |||
---|---|---|---|---|
ALT children | AST children | ALT parents | AST parents | |
PB/AHA | 1 | 1.13 | 0.85 | 0.83 |
(NCT01817491)
Timeframe: Baseline, 4 weeks
Intervention | ratio (Mean) | |
---|---|---|
Children | Parents | |
PB/AHA | 0.95 | 0.93 |
Changes in levels of non-labeled TMAO from baseline to Day 28 measured by established mass spectrometry techniques. (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | mg in 24 hours (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 26.2 | 139.0 |
Egg Whites + Choline Bitartrate Tablets | 29.3 | 186.9 |
Hardboiled Eggs + Choline Bitartrate Tablets | 27.5 | 221.8 |
Phosphatidylcholine Capsules | 15.8 | 33.1 |
Whole Hardboiled Eggs | 24.3 | 28.5 |
Changes in measured HDL levels between baseline and Day 28 (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | mg/dL (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 49 | 51 |
Egg Whites + Choline Bitartrate Tablets | 48 | 50 |
Hardboiled Eggs + Choline Bitartrate Tablets | 57 | 56 |
Phosphatidylcholine Capsules | 61 | 62 |
Whole Hardboiled Eggs | 48 | 49 |
Changes in measured LDL levels between baseline and Day 28 (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | mg/dL (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 90 | 94 |
Egg Whites + Choline Bitartrate Tablets | 104 | 101 |
Hardboiled Eggs + Choline Bitartrate Tablets | 108 | 118 |
Phosphatidylcholine Capsules | 107 | 106 |
Whole Hardboiled Eggs | 91 | 86 |
Changes in total cholesterol levels between baseline and Day 28 (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | mg/dL (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 180 | 172 |
Egg Whites + Choline Bitartrate Tablets | 186 | 178 |
Hardboiled Eggs + Choline Bitartrate Tablets | 187 | 198 |
Phosphatidylcholine Capsules | 175 | 172 |
Whole Hardboiled Eggs | 156 | 158 |
Changes in measured triglyceride levels between baseline and Day 28 (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | mg/dL (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 106 | 96 |
Egg Whites + Choline Bitartrate Tablets | 122 | 109 |
Hardboiled Eggs + Choline Bitartrate Tablets | 103 | 97 |
Phosphatidylcholine Capsules | 74 | 84 |
Whole Hardboiled Eggs | 86 | 100 |
Fasting plasma levels of betaine from samples obtained at baseline and at day 28 were compared. (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | uM (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 38.2 | 69.0 |
Egg Whites + Choline Bitartrate Tablets | 38.7 | 59.8 |
Hardboiled Eggs + Choline Bitartrate Tablets | 30.7 | 46.9 |
Phosphatidylcholine Capsules | 33.6 | 46.3 |
Whole Hardboiled Eggs | 28.1 | 39.7 |
Fasting plasma levels of carnitine from samples obtained at baseline and at day 28 were compared. (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | uM (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 21.2 | 18.7 |
Egg Whites + Choline Bitartrate Tablets | 21.1 | 18.9 |
Hardboiled Eggs + Choline Bitartrate Tablets | 21.5 | 15.6 |
Phosphatidylcholine Capsules | 23.4 | 20.8 |
Whole Hardboiled Eggs | 19.1 | 19.4 |
Fasting plasma levels of choline from samples obtained at baseline and at day 28 were compared. (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | uM (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 7.5 | 12.9 |
Egg Whites + Choline Bitartrate Tablets | 9.5 | 12.8 |
Hardboiled Eggs + Choline Bitartrate Tablets | 8.5 | 14.0 |
Phosphatidylcholine Capsules | 7.6 | 10.6 |
Whole Hardboiled Eggs | 8.3 | 10.9 |
Changes in levels of non-labeled TMAO from baseline to end-of-study (day 28) as measured by established techniques by mass spectrometry. (NCT03039023)
Timeframe: Baseline, 28 days
Intervention | uM (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 1.9 | 11.1 |
Egg Whites + Choline Bitartrate Tablets | 2.6 | 28.1 |
Hardboiled Eggs + Choline Bitartrate Tablets | 2.3 | 12.3 |
Phosphatidylcholine Capsules | 2.8 | 3.4 |
Whole Hardboiled Eggs | 2.0 | 2.3 |
The activation and functioning of platelets within a single subject will be compared before and after increased choline intake. (NCT03039023)
Timeframe: Baseline, Day 28
Intervention | aggregation percentage (Median) | |
---|---|---|
Baseline | Day 28 | |
Choline Bitartrate Tablets | 2.6 | 12.8 |
Egg Whites + Choline Bitartrate Tablets | 3.0 | 29.4 |
Hardboiled Eggs + Choline Bitartrate Tablets | 2.3 | 12.3 |
Phosphatidylcholine Capsules | 2.8 | 3.4 |
Whole Hardboiled Eggs | 2.6 | 3.6 |
7 reviews available for choline and Atherogenesis
Article | Year |
---|---|
The gut microbial metabolite trimethylamine N-oxide and cardiovascular diseases.
Topics: Atherosclerosis; Cardiovascular Diseases; Choline; Gastrointestinal Microbiome; Humans; Methylamines | 2023 |
The roles of trimethylamine-N-oxide in atherosclerosis and its potential therapeutic aspect: A literature review.
Topics: Atherosclerosis; Choline; Endothelial Cells; Humans; Lyases; Oxides; Plaque, Atherosclerotic | 2023 |
The Gut Microbiota Affects Host Pathophysiology as an Endocrine Organ: A Focus on Cardiovascular Disease.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Choline; Diet; Endocrine Gl | 2019 |
Gut Microbiota and Cardiovascular Disease.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Carnitine; Choline; Disease | 2020 |
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids, | 2019 |
The contributory role of gut microbiota in cardiovascular disease.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; I | 2014 |
New aspects on the metabolic role of intestinal microbiota in the development of atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Choline; Humans; Intestinal Mucosa; Intestines; Methyl | 2015 |
1 trial available for choline and Atherogenesis
Article | Year |
---|---|
Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults - a pilot study.
Topics: Adolescent; Adult; Animals; Atherosclerosis; Betaine; Carnitine; Choline; Chylomicrons; Cytokines; D | 2015 |
75 other studies available for choline and Atherogenesis
Article | Year |
---|---|
Integrated metagenomics identifies a crucial role for trimethylamine-producing Lachnoclostridium in promoting atherosclerosis.
Topics: Animals; Atherosclerosis; Choline; Gastrointestinal Microbiome; Humans; Metagenomics; Methylamines; | 2022 |
Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE
Topics: Animals; Atherosclerosis; Cholesterol; Cholesterol, LDL; Choline; Inflammation; Leukocytes, Mononucl | 2022 |
Inhibition of Trimethylamine N-Oxide Attenuates Neointimal Formation Through Reduction of Inflammasome and Oxidative Stress in a Mouse Model of Carotid Artery Ligation.
Topics: Animals; Atherosclerosis; Carotid Arteries; Choline; Disease Models, Animal; Humans; Inflammasomes; | 2023 |
Dietary titanium dioxide particles (E171) promote diet-induced atherosclerosis through reprogramming gut microbiota-mediated choline metabolism in APOE
Topics: Animals; Atherosclerosis; Choline; Diet; Gastrointestinal Microbiome; Methylamines; Mice; Mice, Knoc | 2022 |
Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota.
Topics: Animals; Atherosclerosis; Choline; Cricetinae; Gastrointestinal Microbiome; Methylamines; Vitamins | 2022 |
Phenolic-rich beverages reduce bacterial TMA formation in an
Topics: Atherosclerosis; Bacteria; Beverages; Chlorogenic Acid; Choline; Coffee; Fermentation; Humans; Methy | 2022 |
The associations between TMAO-related metabolites and blood lipids and the potential impact of rosuvastatin therapy.
Topics: Atherosclerosis; Betaine; Carnitine; Cholesterol, LDL; Choline; Humans; Lipids; Methylamines; Rosuva | 2022 |
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1.
Topics: AMP-Activated Protein Kinases; Animals; Atherosclerosis; Choline; Gastrointestinal Microbiome; Infla | 2022 |
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation | 2022 |
Choline and butyrate beneficially modulate the gut microbiome without affecting atherosclerosis in APOE*3-Leiden.CETP mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Butyrates; Cholesterol Ester Transfer Proteins; Choline | 2022 |
Neither Trimethylamine-N-Oxide nor Trimethyllysine Is Associated with Atherosclerosis: A Cross-Sectional Study in Older Japanese Adults.
Topics: Animals; Atherosclerosis; Carnitine; Carotid Intima-Media Thickness; Choline; Cross-Sectional Studie | 2023 |
TRIMETHYLAMINE OXIDE - FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND A POTENTIAL TARGET FOR DIETARY AND PHARMACOLOGICAL INTERVENTIONS.
Topics: Atherosclerosis; Carnitine; Choline; Humans; Methylamines | 2023 |
Choline and trimethylamine N-oxide supplementation in normal chow diet and western diet promotes the development of atherosclerosis in Apoe -/- mice through different mechanisms.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cardiovascular Diseases; Choline; Diet, Western; Dietar | 2023 |
Mangiferin alleviates trimethylamine-
Topics: Animals; Atherosclerosis; Cholesterol; Choline; Female; Gastrointestinal Microbiome; Methylamines; M | 2023 |
Dietary Choline or Trimethylamine N-oxide Supplementation Does Not Influence Atherosclerosis Development in Ldlr-/- and Apoe-/- Male Mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Choline; Dietary Supplements; Male; Methylamines; Mice; | 2020 |
Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism.
Topics: Animals; Atherosclerosis; Choline; Diet; Diet, Atherogenic; Disease Models, Animal; Gene Expression | 2019 |
Plasma levels of trimethylamine-N-oxide can be increased with 'healthy' and 'unhealthy' diets and do not correlate with the extent of atherosclerosis but with plaque instability.
Topics: Animal Feed; Animals; Atherosclerosis; Bacteria; Biomarkers; Carotid Artery Diseases; Choline; Coron | 2021 |
Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Atherosclerosis; Cardiovascular Diseases; | 2021 |
Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome.
Topics: Animals; Atherosclerosis; Berberine; Choline; Diet; Disease Models, Animal; Disease Susceptibility; | 2021 |
Association of Kidney Function With NMR-Quantified Lipids, Lipoproteins, and Metabolic Measures in Mexican Adults.
Topics: Adult; Aged; Aged, 80 and over; Apolipoproteins B; Atherosclerosis; Cholesterol; Choline; Diabetes M | 2021 |
Metformin alleviates choline diet-induced TMAO elevation in C57BL/6J mice by influencing gut-microbiota composition and functionality.
Topics: Akkermansia; Animals; Atherosclerosis; Bifidobacterium; Choline; Diabetes Mellitus, Type 2; Diet; Dy | 2021 |
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Mo | 2018 |
Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe
Topics: Animal Feed; Animals; Aortic Diseases; Atherosclerosis; Bacteria; Cholesterol; Choline; Diet, Wester | 2018 |
Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection.
Topics: Atherosclerosis; Biomarkers; Carotid Arteries; Carotid Artery Diseases; Choline; Female; Gastrointes | 2018 |
Lactobacillus plantarum ZDY04 exhibits a strain-specific property of lowering TMAO via the modulation of gut microbiota in mice.
Topics: Animals; Atherosclerosis; Bacteria; Choline; Female; Gastrointestinal Microbiome; Gastrointestinal T | 2018 |
Hepatic Expression of PEMT, but Not Dietary Choline Supplementation, Reverses the Protection against Atherosclerosis in Pemt-/-/Ldlr-/- Mice.
Topics: Animals; Aorta; Atherosclerosis; Cholesterol; Cholesterol, Dietary; Choline; Diet, Western; Dietary | 2018 |
Guggulsterone, a farnesoid X receptor antagonist lowers plasma trimethylamine-
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cardiotonic Agents; Choline; Clost | 2019 |
microRNA-146a-5p association with the cardiometabolic disease risk factor TMAO.
Topics: Animals; Atherosclerosis; Chlorocebus aethiops; Choline; Cohort Studies; Collaborative Cross Mice; D | 2019 |
Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults.
Topics: Adult; Antiretroviral Therapy, Highly Active; Atherosclerosis; Betaine; Carnitine; Carotid Artery Di | 2019 |
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report.
Topics: Animals; Atherosclerosis; Choline; Disease Models, Animal; Lipid Metabolism; Methylamines; Mice; Mic | 2019 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
Topics: Animals; Atherosclerosis; Carnitine; Cholesterol; Choline; Desmosterol; Female; Humans; Intestines; | 2013 |
Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy.
Topics: Animals; Atherosclerosis; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Choline; Diet, High-Fat; D | 2014 |
Transmission of atherosclerosis susceptibility with gut microbial transplantation.
Topics: Animals; Aorta; Atherosclerosis; Cecum; Choline; Diet; Disease Susceptibility; Female; Gastrointesti | 2015 |
Drug the Bug!
Topics: Animals; Atherosclerosis; Choline; Gastrointestinal Tract; Hexanols; Humans; Lyases; Methylamines | 2015 |
Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cholesterol; Choline; Diet; Feces; Foam Cells; Gastroin | 2015 |
Microbiome: Drugs for your bugs.
Topics: Animals; Atherosclerosis; Choline; Gastrointestinal Tract; Hexanols; Humans; Lyases; Methylamines | 2016 |
Type 2 diabetes enhances arterial uptake of choline in atherosclerotic mice: an imaging study with positron emission tomography tracer ¹⁸F-fluoromethylcholine.
Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; Biomarkers; Choline; Cytokines; Diabetes Mellitus, | 2016 |
Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB.
Topics: Animals; Aorta; Aortitis; Atherosclerosis; Cell Adhesion; Cells, Cultured; Choline; Coculture Techni | 2016 |
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
Topics: Adult; Atherosclerosis; Bariatric Surgery; Betaine; Body Mass Index; Cardiovascular Diseases; Carnit | 2016 |
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors.
Topics: Administration, Oral; Animals; Atherosclerosis; Biomarkers; Choline; Deuterium; Dietary Fats; Enviro | 2016 |
Effect of choline in the prevention of experimental aortic atherosclerosis.
Topics: Aorta; Aortic Diseases; Arteriosclerosis; Atherosclerosis; Choline; Sclerosis | 1948 |
The prevention of experimental atherosclerosis by choline feedings.
Topics: Atherosclerosis; Choline; Humans | 1948 |
Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT.
Topics: Aged; Aged, 80 and over; Aorta; Atherosclerosis; Calcinosis; Carbon Isotopes; Carotid Artery, Common | 2009 |
Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cholesterol; Choline; Databases, Genetic; Diet; Diet, H | 2010 |
Uptake of 11C-choline in mouse atherosclerotic plaques.
Topics: Animals; Apolipoproteins B; Atherosclerosis; Choline; Cryopreservation; Immunohistochemistry; Inflam | 2010 |
Cardiovascular disease: the diet-microbe morbid union.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Choline; Diet; Dietary Fats; | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; D | 2011 |
Atherosclerosis: beyond cholesterol.
Topics: Animals; Atherosclerosis; Carbohydrate Metabolism; Cardiovascular Diseases; Choline; Dietary Fats; G | 2011 |
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation.
Topics: Androgens; Animals; Atherosclerosis; Base Sequence; Bile Acids and Salts; Choline; Diet; Down-Regula | 2013 |
[Lipotropic factors in atherosclerosis].
Topics: Arteriosclerosis; Atherosclerosis; Choline; Inositol; Lipotropic Agents; Methionine | 1953 |
Effect of choline on the development and regression of cholesterol atherosclerosis in rabbits.
Topics: Animals; Arteriosclerosis; Atherosclerosis; Cholesterol; Choline; Rabbits | 1954 |
Clinical studies in blood lipid metabolism. IX. Effect of lipotropic agents on serum lipid partitions in fifty patients with generalized atherosclerosis; a three year study.
Topics: Arteriosclerosis; Atherosclerosis; Biomedical Research; Blood; Choline; Humans; Lipid Metabolism; Li | 1954 |
Susceptibility to experimental atherosclerosis and the methylation of ethanolamine 1,2-C14 to phosphatidyl choline.
Topics: Amino Alcohols; Arteriosclerosis; Atherosclerosis; Choline; Disease Susceptibility; Ethanolamine; Et | 1954 |
Effect of injected choline citrate in experimental atherosclerosis.
Topics: Arteriosclerosis; Atherosclerosis; Blood; Cholesterol; Choline; Injections | 1955 |
[Dynamic activity of cholinesterase and choline content in various forms of atherosclerosis].
Topics: Arteriosclerosis; Atherosclerosis; Choline; Cholinesterases; Humans | 1957 |
Effect of dietary protein and heated fat on serum cholesterol and beta-lipoprotein levels, and on the incidence of experimental atherosclerosis in chicks.
Topics: Animals; Arteriosclerosis; Atherosclerosis; Chickens; Cholesterol; Choline; Dietary Proteins; Fats; | 1958 |
[Changes of cholesterol, choline and protein fractions of blood in atherosclerosis during salt-free diet therapy].
Topics: Arteriosclerosis; Atherosclerosis; Blood Proteins; Cholesterol; Choline; Diet; Diet, Sodium-Restrict | 1957 |
[Changes of choline, cholesterol and cholinesterase in the blood in atherosclerosis].
Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Choline; Choline Deficiency; Cholinesterases | 1958 |
[Changes in the level of prothrombin and fibrinogen of the blood in atherosclerosis in treatment with ascorbic acid, choline and iodine preparations].
Topics: Arteriosclerosis; Ascorbic Acid; Atherosclerosis; Choline; Fibrinogen; Humans; Iodine; Prothrombin; | 1959 |
[Treatment of human atherosclerosis with betaine].
Topics: Arteriosclerosis; Atherosclerosis; Betaine; Choline; Humans | 1961 |
[Activity of the alpha-glycerophosphorylcholine esters of essential fatty acids on the plasma lipoprotein picture after a fatty meal in normal subjects and in patients with atherosclerosis. I. Research on the turbidimetric curve after loading].
Topics: Arteriosclerosis; Atherosclerosis; Choline; Esters; Fatty Acids, Essential; Glycerophosphates; Glyce | 1960 |
[PHARMACOLOGICAL STUDIES ON ATHEROSCLEROSIS AND CORONARY CIRCULATION].
Topics: Acetylcholine; Animals; Arteriosclerosis; Atherosclerosis; Blood Chemical Analysis; Blood Proteins; | 1963 |
[PROBLEMS IN DRUG THERAPY AND ATHEROSCLEROSIS PREVENTION].
Topics: Arteriosclerosis; Atherosclerosis; Choline; Fatty Acids; Folic Acid; Hematinics; Humans; Lipid Metab | 1963 |
[Action of lipotropic factors in atherosclerosis].
Topics: Arteriosclerosis; Atherosclerosis; Choline; Inositol; Lipotropic Agents; Methionine | 1954 |
Effect of dietary protein, methionine and choline on atherosclerosis and serum and liver lipids in cholesterol-fed chickens.
Topics: Animals; Atherosclerosis; Chickens; Cholesterol; Choline; Diet; Dietary Proteins; Lipid Metabolism; | 1960 |
Effect of choline chloride on development of atherosclerosis in the rabbit.
Topics: Animals; Arteriosclerosis; Atherosclerosis; Choline; Rabbits | 1950 |
Effect of choline and inositol on plasma and tissue lipids and atherosclerosis in the cholesterol-fed chick.
Topics: Animals; Arteriosclerosis; Atherosclerosis; Chickens; Cholesterol; Choline; Inositol; Lipids; Plasma | 1950 |
Effect of choline and inositol on plasma and tissue lipids and on spontaneous and stilbestrol-induced atherosclerosis in the chick.
Topics: Animals; Arteriosclerosis; Atherosclerosis; Chickens; Choline; Diethylstilbestrol; Inositol; Lipids; | 1950 |
[Lipotropic factors and atherosclerosis; action of methionine, choline and inositol on experimental cholesterol atherosclerosis].
Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Choline; Inositol; Lipotropic Agents; Methionine | 1950 |
Fiction and facts about lipotropic medication in atherosclerosis.
Topics: Arteriosclerosis; Atherosclerosis; Choline; Humans; Lipotropic Agents | 1952 |
Evaluation of choline in the prevention of experimental atherosclerosis; importance of changes in body weight.
Topics: Arteriolosclerosis; Arteriosclerosis; Atherosclerosis; Body Weight; Body Weights and Measures; Choli | 1950 |
CHOLINE and atherosclerosis.
Topics: Arteriolosclerosis; Arteriosclerosis; Atherosclerosis; Choline; Humans | 1950 |
18F-choline images murine atherosclerotic plaques ex vivo.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Autoradiography; Choline; Choline Kinase; Fluori | 2006 |
Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study.
Topics: Atherosclerosis; Betaine; Choline; Coronary Disease; Diet; Female; Follow-Up Studies; Humans; Incide | 2007 |
Absorption of aortic atherosclerosis by choline feeding.
Topics: Aortic Diseases; Arteriosclerosis; Atherosclerosis; Choline; Humans | 1948 |