choline has been researched along with Astrocytoma in 69 studies
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The choline/N-acetyl-aspartate (Cho/NAA) ratio, obtained by the multivoxel spectroscopy with short echo time (TE), was evaluated, in the histological grading of the brain astrocytomas (grades I, II and III-IV) in comparison with the normal cerebral parenchyma." | 9.12 | [Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas]. ( Aragão, Mde F; Araújo, N; Azevedo Filho, HR; Leite, Cda C; Melo, RV; Otaduy, MC; Silva, JL; Valença, MM; Victor, EG, 2007) |
| "To study choline metabolism in biopsies from nonenhancing Grade 2 (AS2) and Grade 3 (AS3) astrocytomas to determine whether (1) phosphocholine (PC) dominates in AS3, and (2) PC is associated with proliferation or angiogenesis." | 7.77 | Choline metabolism, proliferation, and angiogenesis in nonenhancing grades 2 and 3 astrocytoma. ( Berger, MS; Chang, SM; Chiu, KS; Chu, PW; Cloyd, CP; McKnight, TR; Phillips, JJ; Smith, KJ, 2011) |
| "Uptake of biocytin and biotin was investigated in cultured transformed variants of neuronal (NB2a neuroblastoma) and glial (C6 astrocytoma) CNS cells." | 7.71 | Biocytin and biotin uptake into NB2a neuroblastoma and C6 astrocytoma cells. ( Baumgartner, ER; Baur, B; Suormala, T, 2002) |
| "To report a case of subependymal giant cell astrocytoma (SEGA) in a patient with tuberous sclerosis, emphasizing the proton MR spectroscopy (MRS) findings." | 5.33 | Subependymal giant cell astrocytoma with high choline/creatine ratio on proton MR spectroscopy. ( Bruck, I; de Carvalho Neto, A; Gasparetto, EL, 2006) |
| "Pediatric brain gliomas are not always amenable for complete surgical excision, therefore adjuvant treatment for a large tumor mass is often required." | 5.30 | Variation of post-treatment H-MRSI choline intensity in pediatric gliomas. ( Alger, J; Gupta, RK; Lazareff, JA, 1999) |
| "The choline/N-acetyl-aspartate (Cho/NAA) ratio, obtained by the multivoxel spectroscopy with short echo time (TE), was evaluated, in the histological grading of the brain astrocytomas (grades I, II and III-IV) in comparison with the normal cerebral parenchyma." | 5.12 | [Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas]. ( Aragão, Mde F; Araújo, N; Azevedo Filho, HR; Leite, Cda C; Melo, RV; Otaduy, MC; Silva, JL; Valença, MM; Victor, EG, 2007) |
| "To study choline metabolism in biopsies from nonenhancing Grade 2 (AS2) and Grade 3 (AS3) astrocytomas to determine whether (1) phosphocholine (PC) dominates in AS3, and (2) PC is associated with proliferation or angiogenesis." | 3.77 | Choline metabolism, proliferation, and angiogenesis in nonenhancing grades 2 and 3 astrocytoma. ( Berger, MS; Chang, SM; Chiu, KS; Chu, PW; Cloyd, CP; McKnight, TR; Phillips, JJ; Smith, KJ, 2011) |
| "Our purpose was to investigate whether in vivo proton magnetic resonance spectroscopic imaging, using normalized concentrations of total choline (tCho) and total creatine (tCr), can differentiate between WHO grade I pilocytic astrocytoma (PA) and diffuse, fibrillary WHO grade II astrocytoma (DA) in children." | 3.76 | Proton magnetic resonance spectroscopic imaging in pediatric low-grade gliomas. ( Franz, K; Hattingen, E; Kieslich, M; Lehrbecher, T; Pilatus, U; Porto, L, 2010) |
| "In vivo magnetic resonance spectroscopy (MRS) studies of glial brain tumours reported that higher grade of astrocytoma is associated with increased level of choline-containing compounds (Cho) and decreased levels of N-acetylaspartate (NAA) and creatine and phosphocreatine (Cr)." | 3.73 | In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy. ( Belan, V; Béres, A; De Riggo, J; Dobrota, D; Galanda, M; Likavcanová, K; Liptaj, T; Mlynárik, V; Prónayová, N, 2005) |
| "The ratios of choline (Cho) to N-acetylaspartate (NAA) and Cho to creatine (Cr) in those with high-grade astrocytomas (n=4) were significantly higher than in those with low-grade astrocytomas (n=17) (t=2." | 3.73 | In vivo research in astrocytoma cell proliferation with 1H-magnetic resonance spectroscopy: correlation with histopathology and immunohistochemistry. ( Chen, J; Chen, XL; Huang, SL; Li, T, 2006) |
| "Diffusion tensor imaging (DTI) and MR spectroscopy are noninvasive, quantitative tools for the preoperative assessment of gliomas with which the quantitative parameter fractional anisotropy (FA) and the concentration of neurometabolites N-acetylaspartate (NAA), choline (Cho), creatine (Cr) of the brain can be determined." | 3.73 | Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study. ( Ding, XQ; Fiehler, J; Goebell, E; Hagel, C; Heese, O; Kucinski, T; Nietz, S; Paustenbach, S; Westphal, M; Zeumer, H, 2006) |
| " The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
| "Uptake of biocytin and biotin was investigated in cultured transformed variants of neuronal (NB2a neuroblastoma) and glial (C6 astrocytoma) CNS cells." | 3.71 | Biocytin and biotin uptake into NB2a neuroblastoma and C6 astrocytoma cells. ( Baumgartner, ER; Baur, B; Suormala, T, 2002) |
| "Seven patients responded to tamoxifen therapy (three with glioblastomas multiforme; four with anaplastic astrocytomas), and nine did not (six with glioblastomas multiforme; three with anaplastic astrocytomas)." | 3.70 | Using proton magnetic resonance spectroscopic imaging to predict in vivo the response of recurrent malignant gliomas to tamoxifen chemotherapy. ( Arnold, DL; Caramanos, Z; Langleben, A; LeBlanc, R; Preul, MC; Shenouda, G; Villemure, JG, 2000) |
| " The NAA (N-acetylaspartate)/Cho (choline) ratio of Grade 2 astrocytoma was higher than that of Grade 4." | 3.69 | Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy. ( Bandou, K; Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1995) |
| "(a) Hamartomas showed higher N-acetyl aspartate/creatine, creatine/choline, and N-acetyl aspartate/choline ratios than gliomas." | 3.69 | Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation. ( Castillo, M; Green, C; Greenwood, R; Kwock, L; Schiro, S; Smith, K; Wilson, D, 1995) |
| "We have shown previously that the major source of diglyceride (DG) formed following muscarinic receptor (mAChR) stimulation of 1321N1 astrocytoma cells is phosphatidylcholine (PC) rather than the phosphoinositides (Martinson, E." | 3.68 | Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation. ( Brown, JH; Martinson, EA; Trilivas, I, 1990) |
| "We examined the relationship between phosphatidylcholine (PC) hydrolysis, phosphoinositide hydrolysis, and diacylglycerol (DAG) formation in response to muscarinic acetylcholine receptor (mAChR) stimulation in 1321N1 astrocytoma cells." | 3.67 | Muscarinic receptor activation of phosphatidylcholine hydrolysis. Relationship to phosphoinositide hydrolysis and diacylglycerol metabolism. ( Brown, JH; Goldstein, D; Martinson, EA, 1989) |
| "The choline/NAA ratio was 3." | 2.40 | Proton MR spectroscopic characteristics of pediatric pilocytic astrocytomas. ( Ball, WS; Ballard, E; Dunn, RS; Egnaczyk, GF; Holland, SK; Hwang, JH, 1998) |
| "F-choline PET/MRI scans were performed in 12 patients with proven astrocytic tumors." | 1.42 | 18F-fluoroethylcholine (18F-Cho) PET/MRI functional parameters in pediatric astrocytic brain tumors. ( Alongi, P; Bomanji, JB; Fraioli, F; Gaze, MN; Groves, AM; Hargrave, D; Hyare, H; Michopoulou, S; Shankar, A; Stoneham, S; Syed, R, 2015) |
| "Glycine was detected in 24% of all studies, though with a wide range of signal amplitude and extent of the spatial distributions." | 1.40 | Mapping of glycine distributions in gliomas. ( Behari, S; Gupta, RK; Hussain, N; Maudsley, AA; Parra, NA; Roy, B; Sheriff, S; Stoyanova, R, 2014) |
| "There were 19 pituitary adenomas, 7 gliomas, 5 craniopharyngiomas, 3 chordomas, meningioma, hemangiopericytoma, malignant lymphoma, germinoma, Rathke cleft cyst, and hypothalamic hamartoma (one of each)." | 1.35 | Possible role of single-voxel (1)H-MRS in differential diagnosis of suprasellar tumors. ( Amano, K; Chernov, MF; Hori, T; Iseki, H; Kawamata, T; Kubo, O; Muragaki, Y; Nakamura, R; Ono, Y; Suzuki, T; Takakura, K, 2009) |
| "To report a case of subependymal giant cell astrocytoma (SEGA) in a patient with tuberous sclerosis, emphasizing the proton MR spectroscopy (MRS) findings." | 1.33 | Subependymal giant cell astrocytoma with high choline/creatine ratio on proton MR spectroscopy. ( Bruck, I; de Carvalho Neto, A; Gasparetto, EL, 2006) |
| "Ten patients with untreated gliomas were examined on a 1." | 1.32 | Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas. ( Buslei, R; Fahlbusch, R; Ganslandt, O; Gruber, S; Moser, E; Nimsky, C; Stadlbauer, A, 2004) |
| "We examined 120 patients with brain tumors using a 1." | 1.31 | In vivo proton magnetic resonance spectroscopy of brain tumors. ( Fountas, KN; Gotsis, SD; Johnston, KW; Kapsalaki, EZ; Kapsalakis, JZ; Papadakis, N; Robinson, JS; Smisson , HF, 2000) |
| "Aspirated pus from one patient with brain abscess was examined using ex vivo proton MR spectroscopy." | 1.31 | Discrimination of brain abscess and cystic tumor by in vivo proton magnetic resonance spectroscopy. ( Kadota, O; Kikuchi, K; Kohno, K; Kumon, Y; Miki, H; Ohue, S; Sakaki, S, 2001) |
| "Proton MRS of pediatric posterior fossa tumors seems to be helpful in prediction of tumor grading and histology." | 1.31 | [Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors]. ( Biegański, T; Kreisel, J; Liberski, PP; Nowosławska, E; Polis, L; Zakrzewski, K, 2001) |
| "Pediatric brain gliomas are not always amenable for complete surgical excision, therefore adjuvant treatment for a large tumor mass is often required." | 1.30 | Variation of post-treatment H-MRSI choline intensity in pediatric gliomas. ( Alger, J; Gupta, RK; Lazareff, JA, 1999) |
| "Eleven primitive neuroectodermal tumors (patient age, 2 to 12 years; mean, 7 years), 11 low-grade astrocytomas (age, 2 to 16 years; mean, 9 years), 4 ependymomas (age, 1 to 6 years; mean, 4 years), 1 mixed glioma ependymo-astrocytoma (age, 11 years), 1 anaplastic ependymoma (age, 7 years), 1 ganglioglioma (age, 14 years), and 1 malignant teratoma (age, 6 days) were studied." | 1.29 | Proton MR spectroscopy of pediatric cerebellar tumors. ( Bilaniuk, LT; Cnaan, A; Haselgrove, JC; Rorke, LB; Sutton, LN; Wang, Z; Zhao, H; Zimmerman, RA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.90) | 18.7374 |
| 1990's | 20 (28.99) | 18.2507 |
| 2000's | 38 (55.07) | 29.6817 |
| 2010's | 9 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carlin, D | 1 |
| Babourina-Brooks, B | 1 |
| Davies, NP | 1 |
| Wilson, M | 1 |
| Peet, AC | 1 |
| Maudsley, AA | 1 |
| Gupta, RK | 3 |
| Stoyanova, R | 1 |
| Parra, NA | 1 |
| Roy, B | 1 |
| Sheriff, S | 1 |
| Hussain, N | 1 |
| Behari, S | 1 |
| Fraioli, F | 1 |
| Shankar, A | 1 |
| Hargrave, D | 1 |
| Hyare, H | 1 |
| Gaze, MN | 1 |
| Groves, AM | 1 |
| Alongi, P | 1 |
| Stoneham, S | 1 |
| Michopoulou, S | 1 |
| Syed, R | 1 |
| Bomanji, JB | 1 |
| Carvalho-Neto, Ad | 1 |
| Bruck, I | 2 |
| Antoniuk, SA | 1 |
| Marchiori, E | 1 |
| Gasparetto, EL | 2 |
| Hermann, EJ | 1 |
| Hattingen, E | 3 |
| Krauss, JK | 1 |
| Marquardt, G | 1 |
| Pilatus, U | 3 |
| Franz, K | 3 |
| Setzer, M | 1 |
| Gasser, T | 2 |
| Tews, DS | 1 |
| Zanella, FE | 1 |
| Seifert, V | 1 |
| Lanfermann, H | 1 |
| Chernov, MF | 1 |
| Kawamata, T | 1 |
| Amano, K | 1 |
| Ono, Y | 1 |
| Suzuki, T | 1 |
| Nakamura, R | 1 |
| Muragaki, Y | 1 |
| Iseki, H | 1 |
| Kubo, O | 1 |
| Hori, T | 1 |
| Takakura, K | 1 |
| Righi, V | 1 |
| Roda, JM | 1 |
| Paz, J | 1 |
| Mucci, A | 1 |
| Tugnoli, V | 1 |
| Rodriguez-Tarduchy, G | 1 |
| Barrios, L | 1 |
| Schenetti, L | 1 |
| Cerdán, S | 1 |
| García-Martín, ML | 1 |
| Porto, L | 2 |
| Kieslich, M | 2 |
| Lehrbecher, T | 2 |
| Vlaho, S | 1 |
| Stadlbauer, A | 2 |
| Buchfelder, M | 1 |
| Doelken, MT | 1 |
| Hammen, T | 1 |
| Ganslandt, O | 2 |
| McKnight, TR | 1 |
| Smith, KJ | 1 |
| Chu, PW | 1 |
| Chiu, KS | 1 |
| Cloyd, CP | 1 |
| Chang, SM | 1 |
| Phillips, JJ | 1 |
| Berger, MS | 1 |
| Wächter, T | 1 |
| Engeholm, M | 1 |
| Bisdas, S | 1 |
| Schittenhelm, J | 1 |
| Krüger, R | 1 |
| Vettukattil, R | 1 |
| Gulati, M | 1 |
| Sjøbakk, TE | 1 |
| Jakola, AS | 1 |
| Kvernmo, NA | 1 |
| Torp, SH | 1 |
| Bathen, TF | 1 |
| Gulati, S | 1 |
| Gribbestad, IS | 1 |
| Murphy, M | 2 |
| Loosemore, A | 1 |
| Clifton, AG | 1 |
| Howe, FA | 2 |
| Tate, AR | 1 |
| Cudlip, SA | 2 |
| Wilkins, PR | 1 |
| Griffiths, JR | 2 |
| Bell, BA | 2 |
| Rabinov, JD | 1 |
| Lee, PL | 1 |
| Barker, FG | 1 |
| Louis, DN | 1 |
| Harsh, GR | 1 |
| Cosgrove, GR | 1 |
| Chiocca, EA | 1 |
| Thornton, AF | 1 |
| Loeffler, JS | 1 |
| Henson, JW | 1 |
| Gonzalez, RG | 1 |
| Barton, SJ | 1 |
| Stubbs, M | 1 |
| Saunders, DE | 1 |
| Wilkins, P | 1 |
| Opstad, KS | 1 |
| Doyle, VL | 1 |
| McLean, MA | 1 |
| Bulakbasi, N | 1 |
| Kocaoglu, M | 1 |
| Ors, F | 1 |
| Tayfun, C | 1 |
| Uçöz, T | 1 |
| Bowen, BC | 1 |
| Londoño, A | 1 |
| Castillo, M | 3 |
| Armao, D | 1 |
| Kwock, L | 3 |
| Suzuki, K | 1 |
| Utriainen, M | 1 |
| Komu, M | 1 |
| Vuorinen, V | 1 |
| Lehikoinen, P | 1 |
| Sonninen, P | 1 |
| Kurki, T | 1 |
| Utriainen, T | 1 |
| Roivainen, A | 1 |
| Kalimo, H | 1 |
| Minn, H | 1 |
| Lichy, MP | 2 |
| Bachert, P | 2 |
| Henze, M | 1 |
| Lichy, CM | 1 |
| Debus, J | 2 |
| Schlemmer, HP | 2 |
| Vuori, K | 1 |
| Kankaanranta, L | 1 |
| Häkkinen, AM | 2 |
| Gaily, E | 1 |
| Valanne, L | 1 |
| Granström, ML | 1 |
| Joensuu, H | 1 |
| Blomstedt, G | 1 |
| Paetau, A | 2 |
| Lundbom, N | 2 |
| Tong, Z | 1 |
| Yamaki, T | 1 |
| Harada, K | 1 |
| Houkin, K | 2 |
| Cirak, B | 1 |
| Horská, A | 1 |
| Barker, PB | 1 |
| Burger, PC | 1 |
| Carson, BS | 1 |
| Avellino, AM | 1 |
| Moser, E | 2 |
| Gruber, S | 1 |
| Buslei, R | 1 |
| Nimsky, C | 1 |
| Fahlbusch, R | 1 |
| Magalhaes, A | 1 |
| Godfrey, W | 1 |
| Shen, Y | 1 |
| Hu, J | 1 |
| Smith, W | 1 |
| Fayed, N | 1 |
| Modrego, PJ | 1 |
| Jenkinson, MD | 1 |
| Smith, TS | 1 |
| Joyce, K | 1 |
| Fildes, D | 1 |
| du Plessis, DG | 1 |
| Warnke, PC | 1 |
| Walker, C | 1 |
| Pulkkinen, J | 1 |
| Kauppinen, RA | 2 |
| Hiltunen, Y | 1 |
| Likavcanová, K | 1 |
| Dobrota, D | 1 |
| Liptaj, T | 1 |
| Prónayová, N | 1 |
| Mlynárik, V | 1 |
| Belan, V | 1 |
| Galanda, M | 1 |
| Béres, A | 1 |
| De Riggo, J | 1 |
| Chen, J | 1 |
| Huang, SL | 1 |
| Li, T | 1 |
| Chen, XL | 1 |
| Hamprecht, F | 1 |
| Weber, MA | 1 |
| Schulz-Ertner, D | 1 |
| Kauczor, HU | 1 |
| Goebell, E | 1 |
| Fiehler, J | 1 |
| Ding, XQ | 1 |
| Paustenbach, S | 1 |
| Nietz, S | 1 |
| Heese, O | 1 |
| Kucinski, T | 1 |
| Hagel, C | 1 |
| Westphal, M | 1 |
| Zeumer, H | 1 |
| de Carvalho Neto, A | 1 |
| Aragão, Mde F | 1 |
| Otaduy, MC | 1 |
| Melo, RV | 1 |
| Azevedo Filho, HR | 1 |
| Victor, EG | 1 |
| Silva, JL | 1 |
| Araújo, N | 1 |
| Leite, Cda C | 1 |
| Valença, MM | 1 |
| Zhang, K | 1 |
| Li, C | 1 |
| Liu, Y | 1 |
| Li, L | 1 |
| Ma, X | 1 |
| Meng, X | 1 |
| Feng, D | 1 |
| Hagberg, G | 1 |
| Burlina, AP | 1 |
| Mader, I | 1 |
| Roser, W | 1 |
| Radue, EW | 1 |
| Seelig, J | 1 |
| McBride, DQ | 1 |
| Miller, BL | 1 |
| Nikas, DL | 1 |
| Buchthal, S | 1 |
| Chang, L | 1 |
| Chiang, F | 1 |
| Booth, RA | 1 |
| Kinoshita, Y | 1 |
| Kajiwara, H | 1 |
| Yokota, A | 1 |
| Koga, Y | 1 |
| Harada, M | 1 |
| Tanouchi, M | 1 |
| Nishitani, H | 1 |
| Miyoshi, H | 1 |
| Bandou, K | 1 |
| Kannuki, S | 1 |
| Green, C | 1 |
| Smith, K | 1 |
| Wilson, D | 1 |
| Schiro, S | 1 |
| Greenwood, R | 1 |
| Sutton, LN | 2 |
| Wehrli, SL | 1 |
| Gennarelli, L | 1 |
| Wang, Z | 2 |
| Zimmerman, R | 1 |
| Bonner, K | 1 |
| Rorke, LB | 2 |
| Usenius, JP | 1 |
| Vainio, P | 1 |
| Hernesniemi, J | 1 |
| Kamada, K | 2 |
| Hida, K | 1 |
| Matsuzawa, H | 1 |
| Iwasaki, Y | 1 |
| Abe, H | 1 |
| Nakada, T | 1 |
| Negendank, WG | 1 |
| Sauter, R | 1 |
| Brown, TR | 1 |
| Evelhoch, JL | 1 |
| Falini, A | 1 |
| Gotsis, ED | 1 |
| Heerschap, A | 1 |
| Lee, BC | 1 |
| Mengeot, MM | 1 |
| Padavic-Shaller, KA | 1 |
| Sanders, JA | 1 |
| Spraggins, TA | 1 |
| Stillman, AE | 1 |
| Terwey, B | 1 |
| Vogl, TJ | 1 |
| Wicklow, K | 1 |
| Zimmerman, RA | 2 |
| Preul, MC | 2 |
| Caramanos, Z | 2 |
| Collins, DL | 1 |
| Villemure, JG | 2 |
| Leblanc, R | 2 |
| Olivier, A | 1 |
| Pokrupa, R | 1 |
| Arnold, DL | 2 |
| Tien, RD | 1 |
| Lai, PH | 1 |
| Smith, JS | 1 |
| Lazeyras, F | 1 |
| Cnaan, A | 1 |
| Haselgrove, JC | 1 |
| Zhao, H | 1 |
| Bilaniuk, LT | 1 |
| Hwang, JH | 1 |
| Egnaczyk, GF | 1 |
| Ballard, E | 1 |
| Dunn, RS | 1 |
| Holland, SK | 1 |
| Ball, WS | 1 |
| Lazareff, JA | 2 |
| Bockhorst, KH | 1 |
| Curran, J | 1 |
| Olmstead, C | 1 |
| Alger, JR | 2 |
| Meyerand, ME | 1 |
| Pipas, JM | 1 |
| Mamourian, A | 1 |
| Tosteson, TD | 1 |
| Dunn, JF | 1 |
| Luan, W | 1 |
| Zhang, J | 1 |
| Alger, J | 1 |
| Shenouda, G | 1 |
| Langleben, A | 1 |
| Graves, EE | 1 |
| Nelson, SJ | 1 |
| Vigneron, DB | 1 |
| Chin, C | 1 |
| Verhey, L | 1 |
| McDermott, M | 1 |
| Larson, D | 1 |
| Sneed, PK | 1 |
| Chang, S | 1 |
| Prados, MD | 1 |
| Lamborn, K | 1 |
| Dillon, WP | 1 |
| Ricci, PE | 1 |
| Pitt, A | 1 |
| Keller, PJ | 1 |
| Coons, SW | 1 |
| Heiserman, JE | 1 |
| Smith, JK | 1 |
| Fountas, KN | 1 |
| Kapsalaki, EZ | 1 |
| Gotsis, SD | 1 |
| Kapsalakis, JZ | 1 |
| Smisson , HF | 1 |
| Johnston, KW | 1 |
| Robinson, JS | 1 |
| Papadakis, N | 1 |
| Cloughesy, TF | 1 |
| Sinha, U | 1 |
| Garakian, J | 1 |
| Lazareff, J | 1 |
| Rubino, G | 1 |
| Rubino, L | 1 |
| Becker, DP | 1 |
| Vinters, HV | 1 |
| Kadota, O | 1 |
| Kohno, K | 1 |
| Ohue, S | 1 |
| Kumon, Y | 1 |
| Sakaki, S | 1 |
| Kikuchi, K | 1 |
| Miki, H | 1 |
| Liu, H | 1 |
| Hall, WA | 1 |
| Martin, AJ | 1 |
| Truwit, CL | 1 |
| Ishimaru, H | 1 |
| Morikawa, M | 1 |
| Iwanaga, S | 1 |
| Kaminogo, M | 1 |
| Ochi, M | 1 |
| Hayashi, K | 1 |
| Baur, B | 1 |
| Suormala, T | 1 |
| Baumgartner, ER | 1 |
| Zakrzewski, K | 1 |
| Kreisel, J | 1 |
| Polis, L | 1 |
| Nowosławska, E | 1 |
| Liberski, PP | 1 |
| Biegański, T | 1 |
| Haber, B | 1 |
| Hutchison, HT | 1 |
| Henriksen, O | 1 |
| Wieslander, S | 1 |
| Gjerris, F | 1 |
| Jensen, KM | 1 |
| Martinson, EA | 2 |
| Trilivas, I | 2 |
| Brown, JH | 3 |
| Trejo, J | 1 |
| Martinson, E | 1 |
| Goldstein, D | 1 |
1 review available for choline and Astrocytoma
| Article | Year |
|---|---|
Proton MR spectroscopic characteristics of pediatric pilocytic astrocytomas.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Choline; Humans; Infant; Lacti | 1998 |
5 trials available for choline and Astrocytoma
| Article | Year |
|---|---|
Stereotactic biopsy in gliomas guided by 3-tesla 1H-chemical-shift imaging of choline.
Topics: Adult; Aged; Astrocytoma; Biopsy; Brain; Brain Neoplasms; Choline; Female; Humans; Magnetic Resonanc | 2008 |
[Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Chol | 2007 |
Evaluation of invasiveness of astrocytoma using 1H-magnetic resonance spectroscopy: correlation with expression of matrix metalloproteinase-2.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Hum | 2007 |
Choline-containing compounds in human astrocytomas studied by 1H NMR spectroscopy in vivo and in vitro.
Topics: Astrocytoma; Brain; Brain Neoplasms; Choline; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Pho | 1994 |
Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Pr | 1996 |
63 other studies available for choline and Astrocytoma
| Article | Year |
|---|---|
Variation of T
Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Child; Choline; Creatine; Female; Humans; Magnet | 2019 |
Mapping of glycine distributions in gliomas.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Mapping; Brain Neoplasms; Choline; Diffusion Magn | 2014 |
18F-fluoroethylcholine (18F-Cho) PET/MRI functional parameters in pediatric astrocytic brain tumors.
Topics: Adolescent; Astrocytoma; Brain Neoplasms; Child; Choline; Female; Fluorodeoxyglucose F18; Humans; Ma | 2015 |
Proton MR spectroscopy of the foramen of Monro region in patients with tuberous sclerosis complex.
Topics: Amino Acids; Aspartic Acid; Astrocytoma; Basal Ganglia; Biomarkers, Tumor; Brain Chemistry; Case-Con | 2008 |
Possible role of single-voxel (1)H-MRS in differential diagnosis of suprasellar tumors.
Topics: Adult; Aspartic Acid; Astrocytoma; Chi-Square Distribution; Choline; Craniopharyngioma; Creatine; Di | 2009 |
1H HR-MAS and genomic analysis of human tumor biopsies discriminate between high and low grade astrocytomas.
Topics: Astrocytoma; Biopsy; Choline; Glycerylphosphorylcholine; Humans; Magnetic Resonance Spectroscopy | 2009 |
Spectroscopy of untreated pilocytic astrocytomas: do children and adults share some metabolic features in addition to their morphologic similarities?
Topics: Adolescent; Adult; Age Factors; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Preschool; Cholin | 2010 |
Magnetic resonance spectroscopic imaging for visualization of the infiltration zone of glioma.
Topics: Adult; Aspartic Acid; Astrocytoma; Biopsy; Brain Neoplasms; Choline; Data Interpretation, Statistica | 2011 |
Proton magnetic resonance spectroscopic imaging in pediatric low-grade gliomas.
Topics: Adolescent; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Diagnos | 2010 |
Choline metabolism, proliferation, and angiogenesis in nonenhancing grades 2 and 3 astrocytoma.
Topics: Adult; Astrocytoma; Biopsy; Brain Neoplasms; Cell Proliferation; Choline; Female; Glioma; Glycerylph | 2011 |
Slowly progressive Parkinson syndrome due to thalamic butterfly astrocytoma.
Topics: Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Brain Stem; Choline; Glial Fibrillary Acidic Prot | 2011 |
Differentiating diffuse World Health Organization grade II and IV astrocytomas with ex vivo magnetic resonance spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Fema | 2013 |
The contribution of proton magnetic resonance spectroscopy (1HMRS) to clinical brain tumour diagnosis.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatinine; Humans; Inositol; Magn | 2002 |
In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience.
Topics: Adult; Astrocytoma; Biopsy; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Female; Gliobl | 2002 |
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi | 2003 |
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat | 2003 |
Glial neoplasms without elevated choline-creatine ratios.
Topics: Astrocytoma; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Humans; I | 2003 |
Unusual MR spectroscopic imaging pattern of an astrocytoma: lack of elevated choline and high myo-inositol and glycine levels.
Topics: Adult; Astrocytoma; Brain Neoplasms; Choline; Glycine; Humans; Inositol; Magnetic Resonance Spectros | 2003 |
Evaluation of brain tumor metabolism with [11C]choline PET and 1H-MRS.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carbon Radioisotopes; Choline; Contrast Media; Female; Hu | 2003 |
Monitoring individual response to brain-tumour chemotherapy: proton MR spectroscopy in a patient with recurrent glioma after stereotactic radiotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Astrocytoma; Brain Neoplasms; | 2004 |
Low-grade gliomas and focal cortical developmental malformations: differentiation with proton MR spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Cerebral Cortex; Child; Choline; Creatine; Diagnosis, | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; C | 2004 |
Proton magnetic resonance spectroscopic imaging in pediatric pilomyxoid astrocytoma.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child, Preschool; Choline; Creatine; Female; Humans; In | 2005 |
Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas.
Topics: Adult; Algorithms; Aspartic Acid; Astrocytoma; Automation; Biopsy; Brain Chemistry; Brain Mapping; B | 2004 |
Proton magnetic resonance spectroscopy of brain tumors correlated with pathology.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatin | 2005 |
The contribution of magnetic resonance spectroscopy and echoplanar perfusion-weighted MRI in the initial assessment of brain tumours.
Topics: Adolescent; Adult; Aged; Astrocytoma; Blood Volume; Brain Neoplasms; Child; Child, Preschool; Cholin | 2005 |
MRS of oligodendroglial tumors: correlation with histopathology and genetic subtypes.
Topics: Adult; Aged; Allelic Imbalance; Astrocytoma; Brain Neoplasms; Choline; Chromosomes, Human, Pair 1; C | 2005 |
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glio | 2005 |
In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Choline; Chromium; Creatine; Gliobla | 2005 |
In vivo research in astrocytoma cell proliferation with 1H-magnetic resonance spectroscopy: correlation with histopathology and immunohistochemistry.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Choline; Creatine; Fema | 2006 |
[Application of (1)H MR spectroscopic imaging in radiation oncology: choline as a marker for determining the relative probability of tumor progression after radiation of glial brain tumors].
Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Choline; Combined | 2006 |
Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study.
Topics: Adult; Aged; Anisotropy; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Size; Choline; Cre | 2006 |
Subependymal giant cell astrocytoma with high choline/creatine ratio on proton MR spectroscopy.
Topics: Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child, Preschool; Choline; Creatine; Humans; Magnet | 2006 |
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminan | 1995 |
Analysis of brain tumors using 1H magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Glioblastoma; Humans; Lactates; Magneti | 1995 |
Proton magnetic resonance spectroscopy of astrocytic tumors: an in vitro study.
Topics: Antibodies, Monoclonal; Astrocytoma; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Fe | 1993 |
Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Ependymoma; Glioma; Humans; Magnetic | 1995 |
Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation.
Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Brain; Brain Diseases; Brain Neoplasms; Cerebellar Di | 1995 |
High-resolution 1H-magnetic resonance spectroscopy of pediatric posterior fossa tumors in vitro.
Topics: Adolescent; Alanine; Amino Acids; Animals; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cerebellar N | 1994 |
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr | 1994 |
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.
Topics: Adult; Alanine; Aspartic Acid; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Choline; Creatine; D | 1996 |
Single-voxel proton brain spectroscopy exam (PROBE/SV) in patients with primary brain tumors.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Chemistry; Brain Neoplasms; Choline; Crea | 1996 |
Proton MR spectroscopy of pediatric cerebellar tumors.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain Chemistry; Cerebellar Neoplasms; Child; Child, Prescho | 1995 |
Pediatric low-grade gliomas: prognosis with proton magnetic resonance spectroscopic imaging.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Division; Child; Child, Prescho | 1998 |
Classification of biopsy-confirmed brain tumors using single-voxel MR spectroscopy.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Astrocytoma; Biopsy; Body Water; Brain Neoplasms; | 1999 |
In vivo hydrogen-1 magnetic resonance spectroscopy study of human intracranial tumors.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Female; Humans; Mag | 1998 |
Variation of post-treatment H-MRSI choline intensity in pediatric gliomas.
Topics: Astrocytoma; Biopsy; Brain Neoplasms; Child; Child, Preschool; Choline; Follow-Up Studies; Glioma; H | 1999 |
Using proton magnetic resonance spectroscopic imaging to predict in vivo the response of recurrent malignant gliomas to tamoxifen chemotherapy.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Hormonal; Aspartic Acid; Astro | 2000 |
A preliminary study of the prognostic value of proton magnetic resonance spectroscopic imaging in gamma knife radiosurgery of recurrent malignant gliomas.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Choline; Creatine; Female; Glioblastoma; Humans; Lactic Aci | 2000 |
Effect of voxel position on single-voxel MR spectroscopy findings.
Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glio | 2000 |
Correlation of myo-inositol levels and grading of cerebral astrocytomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child; Chil | 2000 |
In vivo proton magnetic resonance spectroscopy of brain tumors.
Topics: Adult; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Brain; Brain Abscess; Brain Neoplasms; Choline | 2000 |
Relationships between choline magnetic resonance spectroscopy, apparent diffusion coefficient and quantitative histopathology in human glioma.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Choline; Diffusion; Echo-Planar Imaging; Female; Follow-U | 2000 |
Discrimination of brain abscess and cystic tumor by in vivo proton magnetic resonance spectroscopy.
Topics: Acetates; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Bacteria; Biomarkers; Brain Abscess; Child; | 2001 |
An efficient chemical shift imaging scheme for magnetic resonance-guided neurosurgery.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Biopsy; Brain; Brain Mapping; Brain Neop | 2001 |
Differentiation between high-grade glioma and metastatic brain tumor using single-voxel proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chil | 2001 |
Biocytin and biotin uptake into NB2a neuroblastoma and C6 astrocytoma cells.
Topics: Animals; Astrocytoma; Binding, Competitive; Biological Transport; Biotin; Carbon-Carbon Ligases; Cel | 2002 |
[Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors].
Topics: Adolescent; Aspartic Acid; Astrocytoma; Child; Child, Preschool; Choline; Creatine; Diagnosis, Diffe | 2001 |
Uptake of neurotransmitters and precursors by clonal cell lines of neural origin.
Topics: Amino Acids; Aminooxyacetic Acid; Aspartic Acid; Astrocytoma; Biogenic Amines; Cell Line; Cell Membr | 1976 |
In vivo 1H-spectroscopy of human intracranial tumors at 1.5 tesla. Preliminary experience at a clinical installation.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactate | 1991 |
Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation.
Topics: Animals; Astrocytoma; Carbachol; Cell Line; Choline; Diglycerides; Enzyme Activation; Kinetics; Phos | 1990 |
Multiple pathways for signal transduction through the muscarinic cholinergic receptor.
Topics: Animals; Astrocytoma; Calcium; Carbachol; Cell Division; Cell Line; Choline; Ionomycin; Kinetics; Ph | 1990 |
Muscarinic receptor activation of phosphatidylcholine hydrolysis. Relationship to phosphoinositide hydrolysis and diacylglycerol metabolism.
Topics: Arachidonic Acid; Arachidonic Acids; Astrocytoma; Calcium; Carbachol; Cell Line; Choline; Diglycerid | 1989 |