choline has been researched along with Aortic Valve Stenosis in 3 studies
Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In symptomatic patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, circulating levels of long-chain acylcarnitines were independently associated with measures of maladaptive LV remodeling, and metabolic perturbations lessened after procedure completion." | 7.88 | Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. ( Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X, 2018) |
| "In symptomatic patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, circulating levels of long-chain acylcarnitines were independently associated with measures of maladaptive LV remodeling, and metabolic perturbations lessened after procedure completion." | 3.88 | Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. ( Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X, 2018) |
| "Choline-derived TMAO promotes osteogenic differentiation through ER and mitochondrial stress pathways in vitro and aortic valve lesions in vivo." | 1.72 | Trimethylamine N-oxide induces osteogenic responses in human aortic valve interstitial cells in vitro and aggravates aortic valve lesions in mice. ( Ao, L; Lai, W; Li, J; Liu, Z; Meng, X; Ren, H; Xian, G; Xiong, Z; Xu, D; Zeng, Q; Zhan, Q, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kocyigit, D | 1 |
| Tokgozoglu, L | 1 |
| Gurses, KM | 1 |
| Stahlman, M | 1 |
| Boren, J | 1 |
| Soyal, MFT | 1 |
| Canpınar, H | 1 |
| Guc, D | 1 |
| Saglam Ayhan, A | 1 |
| Hazirolan, T | 1 |
| Ozer, N | 1 |
| Li, J | 1 |
| Zeng, Q | 1 |
| Xiong, Z | 1 |
| Xian, G | 1 |
| Liu, Z | 1 |
| Zhan, Q | 1 |
| Lai, W | 1 |
| Ao, L | 1 |
| Meng, X | 1 |
| Ren, H | 1 |
| Xu, D | 1 |
| Elmariah, S | 1 |
| Farrell, LA | 1 |
| Furman, D | 1 |
| Lindman, BR | 1 |
| Shi, X | 1 |
| Morningstar, JE | 1 |
| Rhee, EP | 1 |
| Gerszten, RE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Involvement of the Gut Microbiota and Its Metabolites in the Pathophysiology of Calcified Aortic Stenosis[NCT06021535] | 100 participants (Anticipated) | Observational | 2024-01-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for choline and Aortic Valve Stenosis
| Article | Year |
|---|---|
Association of dietary and gut microbiota-related metabolites with calcific aortic stenosis.
Topics: Aortic Valve; Aortic Valve Stenosis; Betaine; Choline; Gastrointestinal Microbiome; Humans | 2021 |
Trimethylamine N-oxide induces osteogenic responses in human aortic valve interstitial cells in vitro and aggravates aortic valve lesions in mice.
Topics: Animals; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cells, Cultured; Choline; Humans; Methylam | 2022 |
Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
Topics: Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Carnitine; Choline; Diabetes Complications; Fe | 2018 |