choline has been researched along with Alexander Disease in 2 studies
Alexander Disease: Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain. Rosenthal fibers are GLIAL FIBRILLARY ACIDIC PROTEIN aggregates found in ASTROCYTES. Juvenile- and adult-onset types show progressive atrophy of the lower brainstem instead. De novo mutations in the GFAP gene are associated with the disease with propensity for paternal inheritance.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bassuk, AG | 1 |
| Joshi, A | 1 |
| Burton, BK | 1 |
| Larsen, MB | 1 |
| Burrowes, DM | 1 |
| Stack, C | 1 |
| Bizzi, A | 1 |
| Castelli, G | 1 |
| Bugiani, M | 1 |
| Barker, PB | 1 |
| Herskovits, EH | 1 |
| Danesi, U | 1 |
| Erbetta, A | 1 |
| Moroni, I | 1 |
| Farina, L | 1 |
| Uziel, G | 1 |
2 other studies available for choline and Alexander Disease
| Article | Year |
|---|---|
Alexander disease with serial MRS and a new mutation in the glial fibrillary acidic protein gene.
Topics: Acidosis, Respiratory; Alexander Disease; Basal Ganglia; Choline; Creatine; Disease Progression; DNA | 2003 |
Classification of childhood white matter disorders using proton MR spectroscopic imaging.
Topics: Adrenoleukodystrophy; Adult; Alexander Disease; Aspartic Acid; Brain; Child; Child, Preschool; Choli | 2008 |