Page last updated: 2024-10-16

choline and Alcohol Drinking

choline has been researched along with Alcohol Drinking in 20 studies

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
"We recently demonstrated the acceptability and feasibility of a randomized, double-blind choline supplementation intervention for heavy drinking women during pregnancy."9.27Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. ( Carter, RC; Dodge, NC; Duggan, CP; Herbert, JS; Hoyme, HE; Jacobson, JL; Jacobson, SW; Lewis, CE; Lindinger, NM; Meintjes, EM; Molteno, CD; Stanton, ME; Zeisel, SH, 2018)
"Our objectives were to examine whether fetal vulnerability to PAE-related growth restriction is modified by: 1) rate of gestational weight gain; or prenatal dietary intakes of 2) energy, 3) iron, or 4) choline."8.12Gestational weight gain and dietary energy, iron, and choline intake predict severity of fetal alcohol growth restriction in a prospective birth cohort. ( Carter, RC; Dodge, NC; Duggan, CP; Jacobson, JL; Jacobson, SW; Meintjes, EM; Molteno, CD; Senekal, M, 2022)
"Ibudilast-treated participants had lower Cho in superior frontal white matter and nominally lower MI in pregenual anterior cingulate cortex."7.11Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial. ( Alger, J; Burnette, E; Evans, CJ; Grodin, EN; Irwin, MR; London, ED; Meredith, LR; Miotto, K; Nieto, SJ; O'Neill, J; Ray, LA, 2022)
"Seventy heavy drinkers, recruited in mid-pregnancy, were randomly assigned to receive a daily oral dose of 2 g of choline or a placebo from time of enrollment until delivery."5.27Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. ( Carter, RC; Dodge, NC; Duggan, CP; Jacobson, JL; Jacobson, SW; Lindinger, NM; Meintjes, EM; Molteno, CD; Senekal, MS; Zeisel, SH, 2018)
"We recently demonstrated the acceptability and feasibility of a randomized, double-blind choline supplementation intervention for heavy drinking women during pregnancy."5.27Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. ( Carter, RC; Dodge, NC; Duggan, CP; Herbert, JS; Hoyme, HE; Jacobson, JL; Jacobson, SW; Lewis, CE; Lindinger, NM; Meintjes, EM; Molteno, CD; Stanton, ME; Zeisel, SH, 2018)
"Our objectives were to examine whether fetal vulnerability to PAE-related growth restriction is modified by: 1) rate of gestational weight gain; or prenatal dietary intakes of 2) energy, 3) iron, or 4) choline."4.12Gestational weight gain and dietary energy, iron, and choline intake predict severity of fetal alcohol growth restriction in a prospective birth cohort. ( Carter, RC; Dodge, NC; Duggan, CP; Jacobson, JL; Jacobson, SW; Meintjes, EM; Molteno, CD; Senekal, M, 2022)
"Although animal and human studies have demonstrated interactions between dietary choline and fetal alcohol spectrum disorders, dietary choline deficiency in pregnancy is common in the US and worldwide."3.88Development and validation of a quantitative choline food frequency questionnaire for use with drinking and non-drinking pregnant women in Cape Town, South Africa. ( Bechard, LJ; Booley, S; Carter, RC; Dodge, NC; Duggan, CP; Jacobson, JL; Jacobson, SW; Meintjes, EM; Molteno, CD; Najaar, B; Senekal, M, 2018)
"Ibudilast-treated participants had lower Cho in superior frontal white matter and nominally lower MI in pregenual anterior cingulate cortex."3.11Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial. ( Alger, J; Burnette, E; Evans, CJ; Grodin, EN; Irwin, MR; London, ED; Meredith, LR; Miotto, K; Nieto, SJ; O'Neill, J; Ray, LA, 2022)
"There are no biological treatments for fetal alcohol spectrum disorders (FASDs), lifelong conditions associated with physical anomalies, brain damage, and neurocognitive abnormalities."2.78Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. ( Boys, CJ; Brearley, AM; Eckerle, JK; Fink, BA; Fuglestad, AJ; Georgieff, MK; Hoecker, HL; Kroupina, MG; Miller, NC; Wozniak, JR; Zeisel, SH, 2013)
"Choline interventions were administered at different times relative to alcohol exposure, impacting on their success to prevent deficits for specific outcomes."2.58Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies. ( Akison, LK; Boyd, RN; Kuo, J; Moritz, KM; Reid, N, 2018)
"Recent studies demonstrated that alcohol dependence and excessive alcohol consumption are associated with increased rates of obesity."1.36Body mass index is associated with brain metabolite levels in alcohol dependence--a multimodal magnetic resonance study. ( Durazzo, TC; Gazdzinski, S; Meyerhoff, DJ; Mon, A, 2010)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.00)18.7374
1990's0 (0.00)18.2507
2000's4 (20.00)29.6817
2010's10 (50.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Carter, RC4
Senekal, M2
Duggan, CP4
Dodge, NC4
Meintjes, EM4
Molteno, CD4
Jacobson, JL4
Jacobson, SW4
Grodin, EN2
Nieto, SJ1
Meredith, LR1
Burnette, E1
O'Neill, J2
Alger, J2
London, ED1
Miotto, K1
Evans, CJ1
Irwin, MR1
Ray, LA2
Burnette, EM1
Senekal, MS1
Lindinger, NM2
Zeisel, SH5
Stanton, ME1
Herbert, JS1
Lewis, CE1
Hoyme, HE1
Akison, LK1
Kuo, J1
Reid, N1
Boyd, RN1
Moritz, KM1
Booley, S1
Najaar, B1
Bechard, LJ1
Wozniak, JR1
Fuglestad, AJ1
Eckerle, JK1
Kroupina, MG1
Miller, NC1
Boys, CJ1
Brearley, AM1
Fink, BA1
Hoecker, HL1
Georgieff, MK1
Young, JK1
Giesbrecht, HE1
Eskin, MN1
Aliani, M1
Suh, M1
Tunc-Skarka, N1
Weber-Fahr, W1
Ende, G2
Zahr, NM1
Carr, RA1
Rohlfing, T1
Mayer, D1
Sullivan, EV1
Colrain, IM1
Pfefferbaum, A1
Gazdzinski, S1
Durazzo, TC1
Mon, A1
Meyerhoff, DJ1
Swartz, MD1
Peterson, CB1
Lupo, PJ1
Wu, X1
Forman, MR1
Spitz, MR1
Hernandez, LM1
Vannucci, M1
Shete, S1
Cho, E1
Jacques, P1
Selhub, J1
Dougherty, L1
Colditz, GA1
Willett, WC2
Walter, S1
Welzel, H1
Demirakca, T1
Wokrina, T1
Ruf, M1
Ulrich, M1
Diehl, A1
Henn, FA1
Mann, K1
Chiuve, SE1
Giovannucci, EL1
Hankinson, SE1
Dougherty, LW1
Rimm, EB1
Braunová, Z1
Kasparová, S1
Mlynárik, V1
Mierisová, S1
Liptaj, T1
Tkác, I1
Gvozdjáková, A1
Uthus, EO1
Skurdal, DN1
Cornatzer, WE1
Reitz, RC1
Ho, AK1
Kissin, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect on Pregnancy Outcomes, Infant Growth and Development of an Egg Intervention During Pregnancy in Indonesia[NCT04694235]653 participants (Anticipated)Interventional2021-02-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for choline and Alcohol Drinking

ArticleYear
Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies.
    Alcoholism, clinical and experimental research, 2018, Volume: 42, Issue:9

    Topics: Alcohol Drinking; Animals; Animals, Newborn; Choline; Clinical Trials as Topic; Cognition; Cognitive

2018
Nutrition implications for fetal alcohol spectrum disorder.
    Advances in nutrition (Bethesda, Md.), 2014, Volume: 5, Issue:6

    Topics: Alcohol Drinking; Animals; Antioxidants; Brain; Choline; Dietary Supplements; Disease Models, Animal

2014
The effects of ethanol ingestion on lipid metabolism.
    Progress in lipid research, 1979, Volume: 18, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Animals; Bile Acids and Salts; Cholesterol; Choline; Ethanol; Fatty Ac

1979

Trials

5 trials available for choline and Alcohol Drinking

ArticleYear
Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial.
    Addiction biology, 2022, Volume: 27, Issue:4

    Topics: Alcohol Drinking; Alcoholism; Animals; Aspartic Acid; C-Reactive Protein; Choline; Creatine; Humans;

2022
Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Alcoholism, clinical and experimental research, 2018, Volume: 42, Issue:7

    Topics: Alcohol Drinking; Choline; Dietary Supplements; Double-Blind Method; Feasibility Studies; Female; Fe

2018
Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Alcoholism, clinical and experimental research, 2018, Volume: 42, Issue:7

    Topics: Adult; Alcohol Drinking; Birth Weight; Blinking; Choline; Cognition; Dietary Supplements; Double-Bli

2018
Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability.
    Nutrition research (New York, N.Y.), 2013, Volume: 33, Issue:11

    Topics: Alcohol Drinking; Child, Preschool; Choline; Dietary Supplements; Double-Blind Method; Female; Fetal

2013
Recreational alcohol use induces changes in the concentrations of choline-containing compounds and total creatine in the brain: a (1)H MRS study of healthy subjects.
    Magma (New York, N.Y.), 2015, Volume: 28, Issue:5

    Topics: Administration, Oral; Adult; Alcohol Drinking; Brain; Choline; Creatine; Dose-Response Relationship,

2015

Other Studies

12 other studies available for choline and Alcohol Drinking

ArticleYear
Gestational weight gain and dietary energy, iron, and choline intake predict severity of fetal alcohol growth restriction in a prospective birth cohort.
    The American journal of clinical nutrition, 2022, 08-04, Volume: 116, Issue:2

    Topics: Alcohol Drinking; Animals; Birth Cohort; Child; Choline; Diet; Ethanol; Female; Fetal Alcohol Spectr

2022
Alcohol Craving and Severity are Associated with Dorsal Anterior Cingulate Choline Levels in Individuals with an Alcohol Use Disorder.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2023, May-09, Volume: 58, Issue:3

    Topics: Alcohol Drinking; Alcohol-Related Disorders; Alcoholism; Choline; Craving; Ethanol; Gyrus Cinguli; H

2023
Development and validation of a quantitative choline food frequency questionnaire for use with drinking and non-drinking pregnant women in Cape Town, South Africa.
    Nutrition journal, 2018, 11-22, Volume: 17, Issue:1

    Topics: Adult; Alcohol Drinking; Choline; Cohort Studies; Diet; Evaluation Studies as Topic; Female; Humans;

2018
Brain metabolite levels in recently sober individuals with alcohol use disorder: Relation to drinking variables and relapse.
    Psychiatry research. Neuroimaging, 2016, Apr-30, Volume: 250

    Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Aspartic Acid; Brain; Choline; Chronic Dise

2016
Body mass index is associated with brain metabolite levels in alcohol dependence--a multimodal magnetic resonance study.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:12

    Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Aspartic Acid; Body Mass Index; Brain; Choline; Creatine;

2010
Investigating multiple candidate genes and nutrients in the folate metabolism pathway to detect genetic and nutritional risk factors for lung cancer.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Aged; Alcohol Drinking; Bayes Theorem; Betaine; Case-Control Studies; Choline; Female; Ferredoxin-NA

2013
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Betaine; Choline; Female; Folic Acid;

2006
Alcohol consumption significantly influences the MR signal of frontal choline-containing compounds.
    NeuroImage, 2006, Aug-15, Volume: 32, Issue:2

    Topics: Adult; Alcohol Drinking; Choline; Creatinine; Dominance, Cerebral; Dose-Response Relationship, Drug;

2006
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:4

    Topics: Adult; Alcohol Drinking; Betaine; Biomarkers; Choline; Cross-Sectional Studies; Diet Records; Female

2007
Metabolic changes in rat brain after prolonged ethanol consumption measured by 1H and 31P MRS experiments.
    Cellular and molecular neurobiology, 2000, Volume: 20, Issue:6

    Topics: Adenosine Triphosphate; Alcohol Drinking; Alcoholism; Animals; Aspartic Acid; Astrocytes; Brain; Cho

2000
Effect of ethanol ingestion on choline phosphotransferase and phosphatidyl ethanolamine methyltransferase activities in liver microsomes.
    Lipids, 1976, Volume: 11, Issue:9

    Topics: Alcohol Drinking; Animals; Choline; Diacylglycerol Cholinephosphotransferase; Ethanol; Female; Methi

1976
Evidence of a central cholinergic role in alcohol preference.
    Advances in experimental medicine and biology, 1975, Volume: 59

    Topics: Acetylcholine; Acetylcholinesterase; Alcohol Drinking; Animals; Brain; Choline; Cholinesterases; Lit

1975