choline has been researched along with Acute Liver Injury, Drug-Induced in 34 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although mild transient hepatotoxicity associated with aspirin and other salicylates has been well documented, most commonly with high-dose treatment for rheumatologic disorders 112), we report a case of severe hypersensitivity hepatitis with striking tissue and peripheral eosinophilia after ingestion of choline magnesium trisalicylate." | 3.68 | Eosinophilic hepatitis after ingestion of choline magnesium trisalicylate. ( Nadkarni, MM; Peller, CA; Retig, J, 1992) |
| "Cantharidin (CTD) is a promising anticancer drug; however, its dosage is limited by hepatotoxicity." | 1.62 | Protective mechanism of Astragalus Polysaccharides against Cantharidin-induced liver injury determined in vivo by liquid chromatography/mass spectrometry metabolomics. ( Chen, Y; Huang, X; Li, W; Lin, C; Liu, J; Sa, Z; Tang, W; Wang, L; Xu, M; Yang, C, 2021) |
| " The contributions of the metabolites to the separation of control from dosed liver tissues varied depending on the type of spectral editing method used." | 1.32 | Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues. ( Antti, H; Beckonert, O; Bollard, ME; Ebbels, TM; Holmes, E; Keun, H; Lindon, JC; Nicholson, JK; Tang, H; Wang, Y, 2003) |
| "Because of the frequent reports of hepatic toxicity associated with long-term administration of methotrexate, a rat model was developed utilizing daily methotrexate administration." | 1.26 | Choline antagonism of methotrexate liver toxicity in the rat. ( Freeman-Narrod, M, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (61.76) | 18.7374 |
| 1990's | 1 (2.94) | 18.2507 |
| 2000's | 3 (8.82) | 29.6817 |
| 2010's | 4 (11.76) | 24.3611 |
| 2020's | 5 (14.71) | 2.80 |
| Authors | Studies |
|---|---|
| Garnick, L | 1 |
| Bates, C | 1 |
| Massarsky, A | 1 |
| Spencer, P | 1 |
| Sura, P | 1 |
| Monnot, AD | 1 |
| Maier, A | 1 |
| Zan, K | 1 |
| Lei, W | 1 |
| Li, Y | 1 |
| Wang, Y | 2 |
| Liu, L | 1 |
| Zuo, T | 1 |
| Jin, H | 1 |
| Ma, S | 1 |
| Yang, C | 2 |
| Zhao, Y | 2 |
| Ren, D | 3 |
| Yang, X | 3 |
| Sugimoto, M | 1 |
| Hamada, T | 1 |
| Wakabayasi, M | 1 |
| Yoshioka, T | 1 |
| Kato, H | 1 |
| Konishi, H | 1 |
| Nagai, R | 1 |
| Suzuki, M | 1 |
| Numata, Y | 1 |
| Igarashi, Y | 1 |
| Yukioka, H | 1 |
| Huang, X | 1 |
| Tang, W | 1 |
| Lin, C | 1 |
| Sa, Z | 1 |
| Xu, M | 1 |
| Liu, J | 1 |
| Wang, L | 1 |
| Li, W | 1 |
| Chen, Y | 1 |
| Guo, J | 1 |
| Meng, Y | 1 |
| Hu, Y | 1 |
| Naseer, O | 1 |
| Khan, JA | 1 |
| Khan, MS | 1 |
| Omer, MO | 1 |
| Chishti, GA | 1 |
| Sohail, ML | 1 |
| Saleem, MU | 1 |
| Jia, M | 1 |
| Nie, Y | 1 |
| Lin, CC | 1 |
| Yin, MC | 1 |
| Liu, WH | 1 |
| Al-Humadi, H | 1 |
| Theocharis, S | 1 |
| Dontas, I | 1 |
| Stolakis, V | 1 |
| Zarros, A | 1 |
| Kyriakaki, A | 1 |
| Al-Saigh, R | 1 |
| Liapi, C | 1 |
| KNAUFF, HG | 1 |
| GEORGII, A | 1 |
| MATZEN, K | 1 |
| ITO, F | 1 |
| YAMAMURA, Y | 1 |
| HAYANO, K | 1 |
| LOEPER, J | 1 |
| SUEYOSHI, Y | 1 |
| IMAI, Y | 1 |
| QUINN, PS | 1 |
| HIGGINSON, J | 1 |
| Bollard, ME | 1 |
| Keun, H | 1 |
| Antti, H | 1 |
| Beckonert, O | 1 |
| Ebbels, TM | 1 |
| Lindon, JC | 1 |
| Holmes, E | 1 |
| Tang, H | 1 |
| Nicholson, JK | 1 |
| HANDLER, P | 1 |
| FOLLIS, RH | 1 |
| de la HUERGA, J | 1 |
| POPPER, H | 1 |
| EMERSON, WJ | 1 |
| ZAMECNIK, PC | 1 |
| NATHANSON, IT | 1 |
| DYER, HM | 1 |
| SCHAEFER, AE | 1 |
| COPELAND, DH | 1 |
| SALMON, WD | 1 |
| Lee, GS | 1 |
| Yan, JS | 1 |
| Ng, RK | 1 |
| Kakar, S | 1 |
| Maher, JJ | 1 |
| Stachura, J | 1 |
| Tarnawski, A | 1 |
| Szczudrawa, J | 1 |
| Bogdał, J | 1 |
| Mach, T | 1 |
| Klimczyk, B | 1 |
| Kirchmayer, S | 1 |
| Lieber, CS | 1 |
| Freeman-Narrod, M | 1 |
| Nadkarni, MM | 1 |
| Peller, CA | 1 |
| Retig, J | 1 |
| Petzold, H | 2 |
| Neupert, A | 1 |
| Renker, H | 1 |
| Chariatte, N | 1 |
| Dittrich, A | 1 |
| Wegmann, A | 1 |
| Takeuchi, J | 1 |
| Takada, A | 1 |
| Kanayama, R | 1 |
| Ohara, N | 1 |
| Okumura, Y | 1 |
| el-Denshary, ES | 1 |
| Scott, PM | 1 |
| el-Masri, AM | 1 |
| Gaggi, R | 1 |
| Del Mastro, S | 1 |
| Shimizu, Y | 1 |
| Steiner, JW | 1 |
| Perz, ZM | 1 |
| Taichman, LB | 1 |
2 reviews available for choline and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Dose and exposure route analyses inform relationships between liver steatosis and 2-amino-2-methyl-1-propanol: Implications for hazard characterization.
Topics: Adenosine Monophosphate; Animals; Chemical and Drug Induced Liver Injury; Choline; Fatty Liver; Huma | 2022 |
Cytotoxic effects of alcohol on the liver.
Topics: Alcoholism; Amino Acids; Animals; Chemical and Drug Induced Liver Injury; Choline; Dietary Fats; Die | 1977 |
1 trial available for choline and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Comparative Efficacy of Silymarin and Choline Chloride (Liver Tonics) in Preventing the Effects of Aflatoxin B1 in Bovine Calves.
Topics: Aflatoxin B1; Animals; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Choline; Foo | 2016 |
31 other studies available for choline and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Integrative Metabolomics and Proteomics Detected Hepatotoxicity in Mice Associated with Alkaloids from
Topics: Alkaloids; Animals; Chemical and Drug Induced Liver Injury; Choline; Eupatorium; Fibrosis; Glyceroph | 2022 |
Protective Effect of Saponins-Enriched Fraction of Gynostemma pentaphyllum against High Choline-Induced Vascular Endothelial Dysfunction and Hepatic Damage in Mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chemical and Drug Induced L | 2020 |
Sphingomyelin synthase 2 loss suppresses steatosis but exacerbates fibrosis in the liver of mice fed with choline-deficient, L-amino acid-defined, high-fat diet.
Topics: Amino Acids; Animals; Chemical and Drug Induced Liver Injury; Choline; Diet, High-Fat; Fatty Liver; | 2020 |
Protective mechanism of Astragalus Polysaccharides against Cantharidin-induced liver injury determined in vivo by liquid chromatography/mass spectrometry metabolomics.
Topics: Animals; Antineoplastic Agents; Astragalus Plant; ATP-Binding Cassette Transporters; Cantharidin; Ch | 2021 |
Myricetin derived from Hovenia dulcis Thunb. ameliorates vascular endothelial dysfunction and liver injury in high choline-fed mice.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cholesterol; Choline; Drugs, Chinese | 2015 |
Beneficial effects of apple peel polyphenols on vascular endothelial dysfunction and liver injury in high choline-fed mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Glutathione Peroxidase; Humans; Male; Malo | 2017 |
Alleviative effects of s-allyl cysteine and s-ethyl cysteine on MCD diet-induced hepatotoxicity in mice.
Topics: Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; Cholesterol; Choline; Choli | 2008 |
Hepatic injury due to combined choline-deprivation and thioacetamide administration: an experimental approach to liver diseases.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; | 2012 |
[THE EFFECT OF CHOLINE PHOSPHOLIPIDS ON THE SPECTRUM OF FREE PLASMA AMINO ACIDS IN TOXIC LIVER DAMAGE].
Topics: Amino Acids; Blood; Chemical and Drug Induced Liver Injury; Choline; Glycine max; Hepatitis; Linolei | 1963 |
THE FATTY LIVER INDUCTION OF ALPHA-ETHYLTHIOISONICOTINAMIDE (ETHIONIAMIDE, 1314TH).
Topics: Chemical and Drug Induced Liver Injury; Choline; Ethionamide; Fatty Liver; Hepatitis; Nucleosides; P | 1964 |
[THE PROBLEM OF PARENCHYMATOUS REPAIR OF THE LIVER].
Topics: Adenosine Triphosphate; Chemical and Drug Induced Liver Injury; Choline; Hepatectomy; Hepatitis; Liv | 1964 |
INFLUENCE OF LACTOSE ON AMOUNT OF LIVER-FAT IN FATTY LIVERS.
Topics: Carbohydrate Metabolism; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cho | 1964 |
REVERSIBLE AND IRREVERSIBLE CHANGES IN EXPERIMENTAL CIRRHOSIS.
Topics: Amides; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Choline Def | 1965 |
Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues.
Topics: Alanine; Animals; Chemical and Drug Induced Liver Injury; Choline; Glucose; Glycogen; Hydrazines; Li | 2003 |
Influence of age on hepatic response to choline and cystine deficiency in the rat.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Cystine; Liver; Rats | 1950 |
Urinary excretion of choline metabolites following choline administration in normals and patients with hepatobiliary diseases.
Topics: Biliary Tract; Chemical and Drug Induced Liver Injury; Choline; Gastrointestinal Diseases; Humans; L | 1951 |
The effect of sex hormones on hepatic and renal lesions induced in rats by a choline-deficient diet.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Diet; Gonadal Steroid Hormones; Kidney; Li | 1951 |
The effect of supplementary choline on the livers of rats fed p-dimethylaminoazobenzene.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Liver; p-Dimethylaminoazobenzene; Rats | 1951 |
Duodenal ulcers, liver damage, anemia and endema of chronic choline deficiency in dogs.
Topics: Anemia; Animals; Chemical and Drug Induced Liver Injury; Choline; Choline Deficiency; Dogs; Duodenal | 1951 |
Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Choline Deficiency; Diet; Fatty Acids, Uns | 2007 |
Cytoprotective effect of 16, 16' dimethyl prostaglandin E2 and some drugs on an acute galactosamine induced liver damage in rat.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Chemical and Drug Induced Liver Injury; Choline; Drug Combi | 1980 |
Choline antagonism of methotrexate liver toxicity in the rat.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Hydroxyurea; Liver; Liver Diseases; Male; | 1977 |
Eosinophilic hepatitis after ingestion of choline magnesium trisalicylate.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Choline; Eosi | 1992 |
[Enzyme histochemical findings in the rat liver following galactosamine lesions and cholinorotate].
Topics: Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Chemical and Drug Induce | 1972 |
[Liver tissue enzymes in rats with galactosamine hepatitis during simultaneous administration of choline-orotate].
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Chemical and Drug Induced Liver Injury; Ch | 1973 |
[Effect of a new liver therapeutic (ES 914) on allylalcohol damaged rat liver].
Topics: Administration, Oral; Alcoholic Intoxication; Alcohols; Allyl Compounds; Analysis of Variance; Anima | 1972 |
Effect of alcohol on the liver of rats. II. Factors contributing to elevations of plasma transaminase activities and hepatic cell necrosis following a single administration of alcohol in rats.
Topics: Alcohols; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury | 1969 |
Studies on the protective effectiveness of drugs against the hepatic toxicity of primaquine diphosphate in rabbits.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Dexamethasone; Imidazoles; Liver Diseases; | 1969 |
[Protective effect of phosphorylcholine, homocysteine and their combination 1:1 in experimental hepatic lesions rats: comparison with the activity of choline and cysteine].
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Cysteine; | 1969 |
Effect of carbon tetrachloride administration on the synthesis of triglycerides and phospholipids in rat liver.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ch | 1969 |
Cell population dynamics in the liver. A review of quantitative morphological techniques applied to the study of physiological and pathological growth.
Topics: Animals; Cell Division; Chemical and Drug Induced Liver Injury; Cholestasis; Choline; Deficiency Dis | 1966 |