Compounds > cholic acid

cholic acid and Obesity

cholic acid has been researched along with Obesity in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (8.33)	18.2507
2000's	2 (16.67)	29.6817
2010's	6 (50.00)	24.3611
2020's	3 (25.00)	2.80

Authors

Authors	Studies
Auwerx, J; Gioiello, A; Macchiarulo, A; Natalini, B; Pastorini, E; Pellicciari, R; Pruzanski, M; Roda, A; Rosatelli, E; Sardella, R; Schoonjans, K; Thomas, C	1
Aondo Jia, UT; Arman, HD; Chung, E; Estevez, J; Offei, SD; Perez, Y; Yoshimoto, FK	1
Ao, J; Chiba, T; Fujita, N; Iwanaga, T; Kan, M; Kanayama, K; Kanogawa, N; Kanzaki, H; Kato, J; Kato, N; Kishimoto, T; Kiyono, S; Kobayashi, K; Kojima, R; Kondo, T; Koroki, K; Ma, Y; Muroyama, R; Nakagawa, R; Nakamoto, S; Nakamura, M; Ogasawara, S; Saito, T; Sakuma, T; Unozawa, H	1
Gong, J; Peng, C; Tan, C; Wang, Q; Yue, S; Zhao, D	1
Aliakbarian, H; Chaudhari, SN; Devlin, AS; Harris, DA; Henke, MT; Luo, JN; Sheu, EG; Subramaniam, R; Tavakkoli, A; Vernon, AH	1
Adams, AC; Hillgartner, FB; Ippagunta, SM; Kharitonenkov, A	1
Aronow, B; Dexheimer, PJ; Jha, P; Kirby, M; Kohli, R; Myronovych, A; Ryan, KK; Seeley, RJ; Setchell, KD; Zhang, W	1
Auwerx, J; Brindley, DN; Castellani, LW; Champion, MD; Dali-Youcef, N; Devarajan, A; Ford, DA; Jamey, C; Lusis, AJ; Reddy, ST; Reue, K; Shih, DM; Vergnes, L; Yu, JM; Zhang, P	1
Kozak, LP; Zietak, M	1
Fonseca, VA; Staels, B	1
Bloks, VW; Brufau, G; Burgerhof, HG; Kuipers, F; Murphy, EJ; Romijn, HA; Scheltema, RA; Smelt, GH; Stellaard, F	1
Ezaki, O; Higuchi, M; Ikemoto, S; Itakura, H; Kawanaka, K; Maruyama, K; Tabata, I; Takahashi, M; Tange, T; Tsunoda, N; Yamamoto, TT	1

Reviews

1 review(s) available for cholic acid and Obesity

Article	Year
Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration. Diabetes care, 2009, Volume: 32 Suppl 2 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol, HDL; Cholesterol, LDL; Cholic Acid; Diabetes Mellitus; Digestion; Homeostasis; Humans; Intestinal Absorption; Intestines; Liver; Obesity	2009

Other Studies

11 other study(ies) available for cholic acid and Obesity

Article	Year
Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity. Journal of medicinal chemistry, 2009, Dec-24, Volume: 52, Issue:24 Topics: Animals; Chlorocebus aethiops; CHO Cells; Cholic Acids; COS Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Humans; Obesity; Rats; Receptors, G-Protein-Coupled; Stereoisomerism	2009
A synthesis of a rationally designed inhibitor of cytochrome P450 8B1, a therapeutic target to treat obesity. Steroids, 2022, Volume: 178 Topics: Animals; Anti-Obesity Agents; Cholesterol; Cholic Acid; Mice; Obesity; Steroid 12-alpha-Hydroxylase	2022
A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis. Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:10 Topics: Animals; Cholesterol; Cholic Acid; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Fibrosis; Fructose; Insulin Resistance; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Triglycerides	2022
Effects of theabrownin on serum metabolites and gut microbiome in rats with a high-sugar diet. Food & function, 2019, Nov-01, Volume: 10, Issue:11 Topics: Animals; Bacteria; Body Weight; Catechin; Cecum; Cholic Acid; Dietary Sugars; Gastrointestinal Microbiome; Humans; Indoleacetic Acids; Male; Melatonin; Obesity; Rats	2019
Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects. Nature chemical biology, 2021, Volume: 17, Issue:1 Topics: Animals; Anti-Obesity Agents; Bariatric Surgery; Bile; Caco-2 Cells; Cholic Acid; Colon; Gene Expression Regulation; Glucagon-Like Peptide 1; Glucose Tolerance Test; HEK293 Cells; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction; Sulfates	2021
Cholic Acid Supplementation of a High-Fat Obesogenic Diet Suppresses Hepatic Triacylglycerol Accumulation in Mice via a Fibroblast Growth Factor 21-Dependent Mechanism. The Journal of nutrition, 2018, 04-01, Volume: 148, Issue:4 Topics: Acetyl-CoA Carboxylase; Adipose Tissue; Animals; Blood Glucose; Cholic Acid; Diet, High-Fat; Dietary Fats; Dietary Supplements; Energy Metabolism; Fatty Acids; Fatty Liver; Fibroblast Growth Factors; Insulin; Insulin Resistance; Lipogenesis; Liver; Male; Mice; Mice, Knockout; Obesity; Signal Transduction; Sterol Esterase; Triglycerides	2018
Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner. Obesity (Silver Spring, Md.), 2014, Volume: 22, Issue:2 Topics: Animals; Bile Acids and Salts; Caloric Restriction; Cholic Acid; Diet, High-Fat; Down-Regulation; Fatty Liver; Gastroplasty; Gene Expression Profiling; Gene Expression Regulation; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Postprandial Period; Random Allocation; Taurochenodeoxycholic Acid; Triglycerides; Up-Regulation; Weight Loss	2014
PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:4 Topics: Animals; Apolipoproteins E; Aryldialkylphosphatase; Atherosclerosis; Bile Acids and Salts; Chemokine CCL2; Cholesterol, Dietary; Cholic Acid; Diet; Disease Models, Animal; Female; Gallstones; Gene Expression; Genetic Predisposition to Disease; Inflammation Mediators; Interleukin-6; Intestine, Small; Kidney; Lipid Metabolism; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; Obesity	2015
Bile acids induce uncoupling protein 1-dependent thermogenesis and stimulate energy expenditure at thermoneutrality in mice. American journal of physiology. Endocrinology and metabolism, 2016, Mar-01, Volume: 310, Issue:5 Topics: Adiposity; Animals; Bile Acids and Salts; Cholic Acid; Eating; Energy Metabolism; Glucose Tolerance Test; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Ion Channels; Lipogenesis; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Obesity; Phenotype; RNA, Messenger; Thermogenesis; Uncoupling Protein 1	2016
Two time-point assessment of bile acid kinetics in humans using stable isotopes. Isotopes in environmental and health studies, 2010, Volume: 46, Issue:3 Topics: Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholic Acid; Deoxycholic Acid; Deuterium; Diabetes Mellitus, Type 2; Female; Humans; Hypertriglyceridemia; Isotope Labeling; Kinetics; Male; Obesity; Radioisotope Dilution Technique; Reference Values; Time Factors	2010
Cholate inhibits high-fat diet-induced hyperglycemia and obesity with acyl-CoA synthetase mRNA decrease. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1 Topics: Analysis of Variance; Animals; Cholesterol; Cholic Acid; Cholic Acids; Coenzyme A Ligases; Dietary Fats; Energy Intake; Fatty Acids; Fatty Acids, Nonesterified; Feces; Female; Gene Expression Regulation, Enzymologic; Glucose Transporter Type 4; Hyperglycemia; Liver; Mice; Mice, Inbred C57BL; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Phospholipids; Repressor Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Transcription, Genetic; Triglycerides	1997