cholic acid and Liver Diseases

cholic acid has been researched along with Liver Diseases in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19908 (27.59)18.7374
1990's5 (17.24)18.2507
2000's3 (10.34)29.6817
2010's6 (20.69)24.3611
2020's7 (24.14)2.80

Authors

AuthorsStudies
Tsuneyama, K; Watanabe, S1
Ammous, Z; Anderson, JN; Eroglu, Y; Hernandez, E; Heubi, J; Himes, R; Palle, S1
Barbi, E; Burlo, F; Maggiore, G; Matarazzo, L; Maximova, N; Scaramuzza, G; Zanon, D1
Barth, A; Barucha, A; Kauf, E; Lehmann, T; Lüth, S; Mainz, JG; Schneider, J; Tabori, H; Zagoya, C1
Ravindranath, A; Sen Sarma, M; Yachha, SK1
Heubi, JE; Setchell, KDR1
Ali, W; Bush, X; Chen, Q; Chen, Y; Cui, AM; Deng, R; Hashmi, SF; Hurd, Z; Nadolny, C; Qin, G; You, S; Zhang, X1
Bi, HC; Chen, P; Fu, KL; Gao, Y; Guan, LH; Huang, M; Jiang, YM; Liu, JL; Wang, CH; Zhang, HZ; Zhou, YY1
Bove, KE; Heubi, JE; Setchell, KDR1
Berendse, K; Engelen, M; Ferdinandusse, S; Jansen, PLM; Kemper, EM; Klouwer, FCC; Koelfat, KVK; Koot, BGP; Lenicek, M; Poll-The, BT; Schaap, FG; Vaz, FM; Wanders, RJA; Waterham, HR1
Berendse, K; Engelen, M; Ferdinandusse, S; Jansen, PL; Kemper, EM; Klouwer, FC; Koelfat, KV; Koot, BG; Lenicek, M; Poll-The, BT; Schaap, FG; Vaz, FM; Wanders, RJ; Waterham, HR1
Boyer, JL; Hagey, LR; Kulkarni, SR; Soroka, CJ1
Azuma, T; Ekuni, D; Sanbe, T; Tamaki, N; Tomofuji, T; Yamamoto, T1
Hoskins, AC; Lewindon, PJ; O'Connell, NC; Pereira, TN; Ramm, GA; Setchell, KD; Shepherd, RW; Smith, JL1
Kim, MJ; Suh, DJ1
Bosje, JT; Bunch, SE; Rothuizen, J; van den Brom, W1
Mahdawi, R; Mauritz, G; Metz, P; Stockhausen, H; Wildgrube, HJ1
Beckett, GJ; Douglas, JG; Finlayson, ND; Percy-Robb, IW1
Moriwaki, H; Muto, Y; Nishigaki, Y; Ohnishi, H1
Azer, SA; Byth, K; Coverdale, SA; Farrell, GC; Stacey, NH1
Davis, DL; Lathe, R; Lund, EG; O'Connell, NC; Russell, DW; Schwarz, M; Setchell, KD; Sokol, RJ; Thompson, HR; Weslie Tyson, R1
Kase, BF; Sletta, RJ; Solaas, K; Søreide, O1
Berenson, MM; Garcia-Marin, JJ; Welch, V1
Axelson, M; Sjövall, J1
Heymans, HS; Schutgens, RB; Wanders, RJ1
Beynen, AC; De Bruijne, JJ; Katan, MB; Lemmens, AG; Van Zutphen, LF1
De la Pierre, M; Ferraris, R; Fiorentini, MT; Galatola, G; Rolfo, P1
Björkhem, I; Hågå, P; Kase, BF; Pedersen, JI1
Björkhem, I; Kase, BF; Pedersen, JI; Strandvik, B1

Reviews

2 review(s) available for cholic acid and Liver Diseases

ArticleYear
Cholbam® and Zellweger spectrum disorders: treatment implementation and management.
    Orphanet journal of rare diseases, 2021, 09-14, Volume: 16, Issue:1

    Topics: Bile Acids and Salts; Cholic Acid; Humans; Liver Diseases; United States; Zellweger Syndrome

2021
Inborn Errors of Bile Acid Metabolism.
    Clinics in liver disease, 2018, Volume: 22, Issue:4

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Acyl-CoA Oxidase; Adrenal Hyperplasia, Congenital; Amino-Acid N-Acetyltransferase; Bile Acids and Salts; Cholestasis; Cholic Acid; Genetic Testing; Humans; Liver Diseases; Metabolism, Inborn Errors; Racemases and Epimerases; Steroid Hydroxylases; Xanthomatosis, Cerebrotendinous

2018

Trials

4 trial(s) available for cholic acid and Liver Diseases

ArticleYear
Open-label Phase 3 Continuation Study of Cholic Acid in Patients With Inborn Errors of Bile Acid Synthesis.
    Journal of pediatric gastroenterology and nutrition, 2020, Volume: 70, Issue:4

    Topics: Bile Acids and Salts; Cholic Acid; Humans; Liver Diseases; Zellweger Syndrome

2020
Plasma 14C-cholic acid clearance in healthy dogs and dogs with cholestasis or a congenital portosystemic shunt.
    The Veterinary record, 2005, Jul-23, Volume: 157, Issue:4

    Topics: Animals; Carbon Radioisotopes; Cholestasis; Cholic Acid; Dog Diseases; Dogs; Female; Liver Diseases; Male

2005
Sequential changes in serum levels of individual bile acids in patients with chronic cholestatic liver disease.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:3

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholangitis, Sclerosing; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Chronic Disease; Female; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged; Predictive Value of Tests; Prognosis; Survival Rate

1996
Diagnostic value of serum immunoreactive conjugated cholic or chenodeoxycholic acids in detecting hepatobiliary diseases. Comparison with levels of 3 alpha-hydroxy bile acids determined enzymatically and with routine liver tests.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:8

    Topics: Adolescent; Adult; Bile Acids and Salts; Biliary Tract Diseases; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Female; Fluorometry; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Radioimmunoassay; Random Allocation

1987

Other Studies

23 other study(ies) available for cholic acid and Liver Diseases

ArticleYear
Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet.
    The Journal of toxicological sciences, 2013, Volume: 38, Issue:3

    Topics: Animals; Cholesterol Esters; Diet, High-Fat; Eicosapentaenoic Acid; Female; Humans; Inflammation; Inflammation Mediators; Liver; Liver Diseases; Mice; Mice, Inbred ICR; Sodium Cholate; Stearoyl-CoA Desaturase; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Transaminases

2013
Safety and Effectiveness of Compounded Galenic Cholic Acid for Bile Acid Synthesis Disorder: A Case Report.
    Endocrine, metabolic & immune disorders drug targets, 2022, Volume: 22, Issue:10

    Topics: Bile Acids and Salts; Cholestasis; Cholic Acid; Humans; Infant; Liver Cirrhosis; Liver Diseases

2022
Elevated Levels of Toxic Bile Acids in Serum of Cystic Fibrosis Patients with
    International journal of molecular sciences, 2022, Oct-18, Volume: 23, Issue:20

    Topics: Bile Acids and Salts; Cholic Acid; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Pancreatic Insufficiency; Glycine; Humans; Liver Diseases; Mutation; Taurine

2022
Bile acid synthetic defects: Simplified approach in a nutshell.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2020, Volume: 19, Issue:1

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholic Acid; Enzymes; Humans; Liver Diseases; Metabolism, Inborn Errors

2020
Dysregulation of bile acids increases the risk for preterm birth in pregnant women.
    Nature communications, 2020, 04-30, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Animals; Bile Acids and Salts; Carbon Tetrachloride; Cholic Acid; Disease Models, Animal; Female; Hospitals; Humans; Infant, Newborn; Liver Diseases; Male; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; Pregnancy; Pregnancy Outcome; Pregnancy, Animal; Premature Birth; Prospective Studies; Signal Transduction; Young Adult

2020
Hepatic Vps33b deficiency aggravates cholic acid-induced cholestatic liver injury in male mice.
    Acta pharmacologica Sinica, 2022, Volume: 43, Issue:4

    Topics: Animals; Bile Acids and Salts; Cholestasis; Cholic Acid; Liver; Liver Diseases; Male; Mice

2022
The cholic acid extension study in Zellweger spectrum disorders: Results and implications for therapy.
    Journal of inherited metabolic disease, 2019, Volume: 42, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Bile Acids and Salts; Biomarkers; Child; Child, Preschool; Cholic Acid; Female; Humans; Liver; Liver Diseases; Male; Peroxisomes; Young Adult; Zellweger Syndrome

2019
Cholic acid therapy in Zellweger spectrum disorders.
    Journal of inherited metabolic disease, 2016, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Bile Acids and Salts; Bilirubin; Child; Child, Preschool; Cholic Acid; Female; Humans; Liver; Liver Diseases; Longitudinal Studies; Male; PHEX Phosphate Regulating Neutral Endopeptidase; Transaminases; Young Adult; Zellweger Syndrome

2016
Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid-fed mouse model of cholestasis.
    Hepatology (Baltimore, Md.), 2016, Volume: 64, Issue:6

    Topics: Animals; Cholestasis; Cholic Acid; Disease Models, Animal; Heterocyclic Compounds, 4 or More Rings; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Sirtuin 1

2016
Effects of topical application of lipopolysaccharide and proteases on hepatic injury induced by high-cholesterol diet in rats.
    Journal of periodontal research, 2010, Volume: 45, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Topical; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bacterial Proteins; C-Reactive Protein; Cholesterol, Dietary; Cholic Acid; Deoxyguanosine; Escherichia coli; Fatty Liver; Gingiva; Hepatitis; Lipid Peroxides; Lipopolysaccharides; Liver; Liver Diseases; Lysine; Male; Mitochondria, Liver; Peptide Hydrolases; Periodontitis; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Streptomyces griseus

2010
Endogenous ursodeoxycholic acid and cholic acid in liver disease due to cystic fibrosis.
    Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:6

    Topics: Adolescent; Bile Acids and Salts; Child; Child, Preschool; Cholic Acid; Cystic Fibrosis; Female; Humans; Infant; Liver Diseases; Male; Predictive Value of Tests; Prognosis; Ursodeoxycholic Acid

2004
Profiles of serum bile acids in liver diseases.
    The Korean journal of internal medicine, 1986, Volume: 1, Issue:1

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Cholic Acid; Glycocholic Acid; Humans; Liver Diseases; Liver Function Tests

1986
Radioimmunoassay of bile acids in tissue, bile, and urine.
    Clinical chemistry, 1983, Volume: 29, Issue:3

    Topics: Adult; Animals; Bile; Bile Acids and Salts; Cholic Acid; Cholic Acids; Cross Reactions; Female; Glycocholic Acid; Humans; Liver Diseases; Male; Radioimmunoassay; Rats; Rats, Inbred Strains

1983
Differential timing of maximal postprandial concentrations of plasma chenodeoxycholate and cholate: its variability and implications.
    Digestion, 1981, Volume: 22, Issue:5

    Topics: Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Female; Food; Humans; Liver Diseases; Male; Time Factors

1981
Ursodeoxycholic acid corrects defective natural killer activity by inhibiting prostaglandin E2 production in primary biliary cirrhosis.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:7

    Topics: Adult; Aged; Cells, Cultured; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chronic Disease; Deoxycholic Acid; Dinoprostone; Female; Hepatitis C; Humans; Indomethacin; Killer Cells, Natural; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged; Ursodeoxycholic Acid

1996
Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease.
    The Journal of clinical investigation, 1998, Nov-01, Volume: 102, Issue:9

    Topics: Amino Acid Sequence; Animals; Base Sequence; Bile Acids and Salts; Cell Line, Transformed; CHO Cells; Cholic Acid; Cricetinae; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 7; DNA, Complementary; Humans; Infant; Liver; Liver Diseases; Liver Transplantation; Male; Metabolism, Inborn Errors; Microsomes, Liver; Molecular Sequence Data; Mutation; Steroid Hydroxylases; Sterols

1998
Presence of choloyl- and chenodeoxycholoyl-coenzyme A thioesterase activity in human liver.
    Scandinavian journal of clinical and laboratory investigation, 2000, Volume: 60, Issue:2

    Topics: Acyltransferases; Bacterial Proteins; Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholic Acid; Cysts; Dinitrobenzenes; Enzyme Activation; Humans; Liver; Liver Diseases; Peroxisomes; Protein Binding; Subcellular Fractions; Thiolester Hydrolases

2000
Importance of bile acid structure in amelioration of griseofulvin-induced murine protoporphyric hepatopathy.
    The Journal of laboratory and clinical medicine, 1991, Volume: 118, Issue:1

    Topics: Absorption; Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis, Intrahepatic; Cholic Acid; Cholic Acids; Female; Griseofulvin; Liver; Liver Diseases; Mice; Protoporphyrins; Structure-Activity Relationship; Ursodeoxycholic Acid

1991
Potential bile acid precursors in plasma--possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man.
    Journal of steroid biochemistry, 1990, Aug-28, Volume: 36, Issue:6

    Topics: Adult; Aged; Chenodeoxycholic Acid; Cholestenes; Cholestenones; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cholic Acids; Female; Health Status; Humans; Intestinal Absorption; Liver Diseases; Male; Middle Aged; Models, Biological

1990
Deficient cholesterol side chain oxidation in patients without peroxisomes (Zellweger syndrome): evidence for the involvement of peroxisomes in bile acid synthesis in man.
    Clinica chimica acta; international journal of clinical chemistry, 1987, Feb-15, Volume: 162, Issue:3

    Topics: Bile Acids and Salts; Brain Diseases; Chenodeoxycholic Acid; Cholesterol; Cholic Acid; Cholic Acids; Humans; Kidney Diseases; Liver; Liver Diseases; Microbodies; Oxidation-Reduction; Protein Processing, Post-Translational; Syndrome

1987
Cholesterol metabolism and esterases in four strains of rats with differential cholesterolemic responses to a high-cholesterol, high-cholate diet.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1987, Volume: 87, Issue:1

    Topics: Animals; Body Weight; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Cholic Acid; Cholic Acids; Diet; Electrophoresis, Polyacrylamide Gel; Esterases; Hypercholesterolemia; Lipoproteins; Liver; Liver Diseases; Male; Rats; Rats, Inbred Strains; Species Specificity

1987
Defective peroxisomal cleavage of the C27-steroid side chain in the cerebro-hepato-renal syndrome of Zellweger.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:2

    Topics: Bile; Bile Acids and Salts; Cholic Acid; Cholic Acids; Female; Humans; Infant, Newborn; Kidney Diseases; Liver; Liver Diseases; Microbodies; Syndrome

1985
In vivo and vitro studies on formation of bile acids in patients with Zellweger syndrome. Evidence that peroxisomes are of importance in the normal biosynthesis of both cholic and chenodeoxycholic acid.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:6

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestenones; Cholic Acid; Cholic Acids; Humans; Kinetics; Liver Diseases; Metabolic Clearance Rate; Microbodies; Subcellular Fractions; Syndrome

1985