cholic acid has been researched along with Disease Models, Animal in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.26) | 18.7374 |
| 1990's | 5 (8.77) | 18.2507 |
| 2000's | 7 (12.28) | 29.6817 |
| 2010's | 33 (57.89) | 24.3611 |
| 2020's | 9 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J; Li, Q; Meng, H; Wang, C; Wang, S; Wu, Z; Xu, Y; Zhang, A; Zhang, J | 1 |
| Badawi, AM; Elrehany, M; Maher, SA; Mansour, HF; Mohamad, SA; Safwat, MA | 1 |
| Cai, XB; Gao, Q; Guo, LL; Huang, C; Qi, XS; Wan, XJ | 1 |
| Cona, MM; Fang, Z; Gao, M; Ji, Y; Jiang, C; Jiang, X; Li, Y; Liu, W; Ni, Y; Sun, Z; Wang, J; Wang, Q; Wang, X; Yao, N; Yin, Z; Zhan, Y; Zhang, J | 1 |
| Cona, MM; Feng, Y; Li, Y; Ni, Y; Oyen, R; Verbruggen, A; Zhang, J | 1 |
| Cai, XB; Dong Yuan, X; Li, BW; Lu, LG; Qi, XS; Qin Qian, Y; Wan, XJ; Wang, XP; Xu, ZJ; Yang, Q; Zhang, RL; Zhang, WX | 1 |
| Chen, ZH; Jiang, X; Liang, N; Shen, L; Xie, ZG; Yang, CY | 1 |
| Ao, J; Chiba, T; Fujita, N; Iwanaga, T; Kan, M; Kanayama, K; Kanogawa, N; Kanzaki, H; Kato, J; Kato, N; Kishimoto, T; Kiyono, S; Kobayashi, K; Kojima, R; Kondo, T; Koroki, K; Ma, Y; Muroyama, R; Nakagawa, R; Nakamoto, S; Nakamura, M; Ogasawara, S; Saito, T; Sakuma, T; Unozawa, H | 1 |
| Adorini, L; Colliva, C; Fosso, B; Gadaleta, RM; Gioiello, A; Intranuovo, M; Marzano, M; Moschetta, A; Notario, E; Passeri, D; Pellicciari, R; Pesole, G | 1 |
| Caderni, G; D'Ambrosio, M; Femia, AP; Luceri, C | 1 |
| Asakawa, E; Fukuda, A; Hisano, M; Ichimura, M; Narita, S; Omagari, K; Sasao, M; Suruga, K; Tanaka, K; Tsuneyama, K | 1 |
| Feng, W; Hao, Z; Liu, Y; Ren, L; Song, Q; Zhang, L | 1 |
| Bai, X; Dai, F; Hong, SJ; Hong, YP; Sohn, WM; Song, JH | 1 |
| Ali, W; Bush, X; Chen, Q; Chen, Y; Cui, AM; Deng, R; Hashmi, SF; Hurd, Z; Nadolny, C; Qin, G; You, S; Zhang, X | 1 |
| Chang, E; Kim, CT; Kim, IH; Kim, J; Kim, Y; Lee, J; Lee, MS; Lee, S; Lee, Y | 1 |
| Kawaguchi, H; Komohara, Y; Nakagawa, T; Tanimoto, A; Yamada, S; Yoshii, D | 1 |
| Chen, L; Wang, C; Wu, Y | 1 |
| Guo, X; Hamada, T; Kawaguchi, H; Matsuo, K; Miura, N; Tanimoto, A; Tasaki, T; Yamada, S; Yamada, T | 1 |
| Bi, H; Chen, P; Chen, X; Chen, Y; Fu, K; Guan, L; Huang, M; Jiang, Y; Li, D; Li, X; Sun, J; Zeng, X; Zhang, H | 1 |
| Deuschle, U; Fujimoto, M; Hijikata, T; Nishida, T; Taira, S; Takahashi, T; Tsuneyama, K | 1 |
| Fotschki, B; Jurgoński, A; Juśkiewicz, J; Koza, J; Opyd, PM | 1 |
| Boehme, S; Chiang, JYL; Ferrell, JM; Gilliland, T; Pathak, P | 1 |
| Cheng, W; Li, P; Liu, J; Wang, Y; Zhang, J; Zhang, Z | 1 |
| Abraham, A; Janeesh, PA | 1 |
| Aubrecht, J; Colangelo, JL; Houle, C; Luo, L; Schomaker, S | 1 |
| Desai, MS; Eblimit, Z; Karpen, SJ; Kosters, A; Moore, DD; Penny, DJ; Thevananther, S | 1 |
| Auwerx, J; Brindley, DN; Castellani, LW; Champion, MD; Dali-Youcef, N; Devarajan, A; Ford, DA; Jamey, C; Lusis, AJ; Reddy, ST; Reue, K; Shih, DM; Vergnes, L; Yu, JM; Zhang, P | 1 |
| da Costa, KA; Fiorucci, S; Goedken, MJ; Guo, G; Jaeschke, H; Kong, B; Lebofsky, M; Lee, S; Orena, SJ; Renga, B; Rudraiah, S; Smalling, R; Tsuchiya, H; Wang, L; Yang, Z; Zeisel, SH; Zhang, Y | 1 |
| Bonde, Y; Rudling, M | 1 |
| Chen, Y; Fickert, P; Gassler, N; Guldiken, N; Haybaeck, J; Jeon, MK; Mohammed, HH; Pollheimer, MJ; Spurny, M; Strnad, P; Trautwein, C | 1 |
| Ashfaq, S; de los Santos, M; DeMorrow, S; Frampton, G; Grant, S; McMillin, M; Quinn, M | 1 |
| Cui, K; Li, R; Li, X; Liu, J; Qiu, J; Rao, K; Wang, S; Wang, T; Wen, B; Yu, G | 1 |
| Boyer, JL; Hagey, LR; Kulkarni, SR; Soroka, CJ | 1 |
| Jeong, H; Kent, R; Pan, X; Won, KJ | 1 |
| Cuperus, FJ; Hafkamp, AM; Havinga, R; Ostrow, JD; Tiribelli, C; Verkade, HJ; Vitek, L; Zelenka, J | 1 |
| Andersson, KE; Bergenståhl, B; Hellstrand, P; Immerstrand, T; Lindholm, MW; Oste, R; Swärd, K | 1 |
| Acuña, M; Amigo, L; Balboa, E; Castro, J; Miquel, JF; Molina, H; Morales, MG; Nervi, F; Rigotti, A; Zanlungo, S | 1 |
| Anastasiou, I; Kyroudi-Voulgari, A; Mitropoulos, D; Perea, D; Ploumidou, K | 1 |
| Beutler, B; Schnabl, B; Siggs, OM; Webb, B | 1 |
| Leber, JH; Quillin, SJ; Schwartz, KT | 1 |
| Chang, MH; Chen, HL; Chen, YH; Chien, CS; Chou, SP; Ling, V; Wang, R; Wu, SH; Yuan, RH | 1 |
| Anzivino, C; Bertolotti, M; Carubbi, F; Carulli, N; Del Puppo, M; Gabbi, C; Loria, P; Losi, L; Macchioni, D; Odoardi, MR; Ricchi, M; Romagnoli, D; Tagliafico, E | 1 |
| Bettaieb, A; Chouinard, ML; Cummings, BP; Giulivi, C; Graham, JL; Haj, FG; Hansen, F; Havel, PJ; Jelsing, J; Kim, J; Kowala, M; Ma, F; Shibata, N; Stanhope, KL; Vrang, N | 1 |
| Forrest, D; Lam, P; Ling, V; Liu, L; Mignault, D; Phillips, MJ; Wang, R; Yousef, IM | 1 |
| Denk, H; Fickert, P; Fuchsbichler, A; Marschall, HU; Trauner, M; Wagner, M; Zatloukal, K; Zollner, G | 1 |
| Ishihara, S; Kadowaki, Y; Kazumori, H; Kinoshita, Y; Rumi, MA | 1 |
| Björkhem, I; Eggertsen, G; Einarsson, C; Gåfvels, M; Murphy, C; Rudling, M; Wang, J | 1 |
| Chung, HR; Feeney, LA; Kim, K; Tomayko, EJ; Wilund, KR | 1 |
| Ding, YL; Tan, L | 1 |
| Chen, TS; Ness, GC; Salen, G; Salen, L; Shefer, S; Tint, GS; Xu, G; Zhao, Z | 1 |
| Blázovics, A; Fehér, J; Horváth, EM; Kemény, T; Vásárhelyi, B; Weinbrenner, Z | 1 |
| Prystowsky, JB; Rege, RV | 1 |
| Cybulsky, MI; Hajra, L; Iiyama, K; Lichtman, AH | 1 |
| Ceryak, S; Fromm, H; Malavolti, M; Shehan, KL | 1 |
| Cohen, BI; Matoba, N; McSherry, CK; Mosbach, EH; Stenger, RJ | 1 |
| Allievi, L; Dall'Aglio, E; Franceschini, G; Lovati, MR; Sirtori, CR; Zavaroni, I | 1 |
| Acalovschi, M; Craciun, C; Craciun, V; Dumitrascu, D; Grigorescu, M | 1 |
1 review(s) available for cholic acid and Disease Models, Animal
| Article | Year |
|---|---|
Leukocyte adhesion molecules in atherogenesis.
Topics: Animals; Arteriosclerosis; Cell Adhesion Molecules; Cholic Acid; Diet; Disease Models, Animal; Leukocytes; Mice; Mice, Transgenic | 1999 |
56 other study(ies) available for cholic acid and Disease Models, Animal
| Article | Year |
|---|---|
Rapid and improved oral absorption of N-butylphthalide by sodium cholate-appended liposomes for efficient ischemic stroke therapy.
Topics: Animals; Area Under Curve; Benzofurans; Caco-2 Cells; Chemistry, Pharmaceutical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug Liberation; Humans; Ischemic Stroke; Liposomes; Male; Neuroprotective Agents; Particle Size; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Cholate; Tissue Distribution | 2021 |
A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced allergic rhinitis.
Topics: Administration, Intranasal; Animals; Calorimetry, Differential Scanning; Disease Models, Animal; Dopamine Antagonists; Drug Combinations; Drug Liberation; Emulsions; Glycerol; Glycine max; Histamine H1 Antagonists, Non-Sedating; In Vitro Techniques; Interleukin-1; Lecithins; Loratadine; Nanostructures; Nasal Mucosa; Olive Oil; Ovalbumin; Paranasal Sinuses; Polysorbates; Rabbits; Rhinitis, Allergic; Sodium Cholate; Spectroscopy, Fourier Transform Infrared; Sulpiride; Surface-Active Agents; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2021 |
Drug-eluting fully covered self-expanding metal stent for dissolution of bile duct stones
Topics: Alloys; Animals; Common Bile Duct; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug-Eluting Stents; Edetic Acid; Gallstones; Humans; Male; Nanofibers; Polyesters; Self Expandable Metallic Stents; Sodium Cholate; Swine; Swine, Miniature; Treatment Outcome | 2019 |
Improvement of solubility and targetability of radioiodinated hypericin by using sodium cholate based solvent in rat models of necrosis.
Topics: Animals; Anthracenes; Disease Models, Animal; Iodine Radioisotopes; Liver; Magnetic Resonance Imaging; Male; Muscle, Skeletal; Necrosis; Perylene; Rats, Sprague-Dawley; Sodium Cholate; Solubility; Solvents; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2014 |
Sodium cholate, a solubilizing agent for the necrosis avid radioiodinated hypericin in rabbits with acute myocardial infarction.
Topics: Animals; Anthracenes; Autoradiography; Disease Models, Animal; Gamma Cameras; Heart; Iodine Radioisotopes; Male; Microscopy, Fluorescence; Molecular Structure; Myocardial Infarction; Myocardium; Necrosis; Perylene; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Sodium Cholate; Solubility; Solutions; Tissue Distribution | 2015 |
Safety and efficacy of a novel plastic stent coated with stone-dissolving agents for the treatment of biliary stones in a porcine model.
Topics: Alanine Transaminase; Amylases; Animals; Aspartate Aminotransferases; Calcium Chelating Agents; Cholangiography; Disease Models, Animal; Drug-Eluting Stents; Edetic Acid; Gallstones; Leukocyte Count; Plastics; Sodium Cholate; Swine | 2015 |
[Experimental studies of therapeutic effect of Rheum officinale on acute pancreatitis].
Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Interleukin-1beta; Male; Pancreas; Pancreatitis; Plants, Medicinal; Rats; Rats, Wistar; Rheum; Sodium Cholate; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis.
Topics: Animals; Cholesterol; Cholic Acid; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Fibrosis; Fructose; Insulin Resistance; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Triglycerides | 2022 |
Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow.
Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Cholic Acid; Disease Models, Animal; Liver; Mice | 2022 |
High Sensitivity to Cholic Acid-induced Colonic Tumorigenesis Makes Female PIRC Rats (F344/NTac-Apc
Topics: Adenomatous Polyposis Coli; Animals; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Cholic Acid; Colorectal Neoplasms; Disease Models, Animal; Female; Gene Expression; Genes, APC; Mutation; Precancerous Conditions; Rats | 2019 |
Dietary fat, cholesterol, and cholic acid affect the histopathologic severity of nonalcoholic steatohepatitis in Sprague-Dawley rats.
Topics: Animals; Cholesterol, Dietary; Cholic Acid; Dietary Fats; Disease Models, Animal; Liver Cirrhosis; Liver Cirrhosis, Experimental; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley | 2019 |
Probiotic Lactobacillus rhamnosus GG prevents progesterone metabolite epiallaopregnanolone sulfate-induced hepatic bile acid accumulation and liver injury.
Topics: Angiogenic Proteins; Animals; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Liver; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Probiotics; RNA-Binding Proteins; Signal Transduction; Ursodeoxycholic Acid | 2019 |
Dopaminergic antagonists inhibit bile chemotaxis of adult Clonorchis sinensis and its egg production.
Topics: Animals; Anthelmintics; Antipsychotic Agents; Bile; Chemotactic Factors; Chemotaxis; Cholic Acid; Clonorchiasis; Clonorchis sinensis; Disease Models, Animal; Dopamine Antagonists; Female; Fertility; Humans; Lithocholic Acid; Rabbits; Survival Analysis; Treatment Outcome | 2020 |
Dysregulation of bile acids increases the risk for preterm birth in pregnant women.
Topics: Adolescent; Adult; Animals; Bile Acids and Salts; Carbon Tetrachloride; Cholic Acid; Disease Models, Animal; Female; Hospitals; Humans; Infant, Newborn; Liver Diseases; Male; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; Pregnancy; Pregnancy Outcome; Pregnancy, Animal; Premature Birth; Prospective Studies; Signal Transduction; Young Adult | 2020 |
Mulberry Fruit Extract Promotes Serum HDL-Cholesterol Levels and Suppresses Hepatic microRNA-33 Expression in Rats Fed High Cholesterol/Cholic Acid Diet.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 5; Bile Acids and Salts; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholesterol, HDL; Cholic Acid; Disease Models, Animal; Fruit; Gene Expression Regulation; Hypercholesterolemia; Lipoproteins; Lipoproteins, LDL; Liver; Liver X Receptors; Male; MicroRNAs; Morus; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sterol Regulatory Element Binding Protein 2 | 2020 |
Phenotypic Changes in Macrophage Activation in a Model of Nonalcoholic Fatty Liver Disease using Microminipigs.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cholesterol; Cholic Acid; Diet, High-Fat; Disease Models, Animal; Disease Progression; Hepatic Stellate Cells; Lymphocytes; Macrophage Activation; Macrophages; Non-alcoholic Fatty Liver Disease; Phenotype; Receptors, Cell Surface; Swine; Swine, Miniature | 2021 |
Cholesterol (Blood lipid) lowering potential of Rosuvastatin chitosan nanoparticles for atherosclerosis: Preclinical study in rabbit model.
Topics: Animals; Anticholesteremic Agents; Aortic Valve; Aortic Valve Stenosis; Atherosclerosis; Biomarkers; Calcinosis; Calcium; Chitosan; Cholesterol; Cholesterol, LDL; Cholic Acid; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Hypercholesterolemia; Interleukin-6; Male; Nanoparticles; Particle Size; Rabbits; Rosuvastatin Calcium; Treatment Outcome | 2020 |
Cholic Acid Enhances Visceral Adiposity, Atherosclerosis and Nonalcoholic Fatty Liver Disease in Microminipigs.
Topics: Adiposity; Animals; Atherosclerosis; Cholic Acid; Diet, High-Fat; Disease Models, Animal; Male; Non-alcoholic Fatty Liver Disease; Obesity, Abdominal; Swine; Swine, Miniature | 2017 |
p53-mediated regulation of bile acid disposition attenuates cholic acid-induced cholestasis in mice.
Topics: Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Bile Acids and Salts; Cholestasis; Cholic Acid; Cytochrome P450 Family 2; Disease Models, Animal; Doxorubicin; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Steroid Hydroxylases; Sulfotransferases; Tumor Suppressor Protein p53; Up-Regulation | 2017 |
Tsumura-Suzuki obese diabetic mice-derived hepatic tumors closely resemble human hepatocellular carcinomas in metabolism-related genes expression and bile acid accumulation.
Topics: Acyltransferases; Aldehyde Reductase; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Betaine-Aldehyde Dehydrogenase; Carcinoma, Hepatocellular; Cholic Acid; Diabetes Mellitus, Experimental; Disease Models, Animal; Down-Regulation; Gene Expression; Glutamate-Ammonia Ligase; Humans; Liver Neoplasms; Male; Mice; Mice, Obese; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Taurocholic Acid | 2018 |
Comparative Effects of Native and Defatted Flaxseeds on Intestinal Enzyme Activity and Lipid Metabolism in Rats Fed a High-Fat Diet Containing Cholic Acid.
Topics: Animal Feed; Animals; Bacteria; Cholic Acid; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Flax; Gastrointestinal Microbiome; Glycolysis; Intestines; Kidney; Lipid Metabolism; Lipid Peroxidation; Lipids; Liver; Male; Metabolic Diseases; Rats, Wistar; Seeds | 2018 |
Deficiency of Both Farnesoid X Receptor and Takeda G Protein-Coupled Receptor 5 Exacerbated Liver Fibrosis in Mice.
Topics: Animals; Bile Acids and Salts; Biopsy, Needle; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Diet, Western; Disease Models, Animal; Disease Progression; Fatty Liver; Gene Expression Regulation; Immunohistochemistry; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Random Allocation; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Signal Transduction | 2019 |
Ameliorative effects of a combination of baicalin, jasminoidin and cholic acid on ibotenic acid-induced dementia model in rats.
Topics: Alzheimer Disease; Animals; Cholic Acid; Dementia; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Humans; Ibotenic Acid; Iridoids; Male; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Rats | 2013 |
Amelioration of cholesterol induced atherosclerosis by normalizing gene expression, cholesterol profile and antioxidant enzymes by Vigna unguiculata.
Topics: Animals; Antioxidants; Aorta; Aryldialkylphosphatase; Atherosclerosis; Cholesterol; Cholic Acid; Cyclooxygenase 2; Dietary Supplements; Disease Models, Animal; Enzymes; Fabaceae; Gene Expression Regulation; Hypolipidemic Agents; Interleukin-10; Interleukin-6; Lipid Peroxidation; Male; Plant Extracts; Plant Leaves; Rabbits; Reactive Oxygen Species | 2013 |
Evaluation of serum bile acid profiles as biomarkers of liver injury in rodents.
Topics: Animals; Bile Acids and Salts; Bile Ducts; Biomarkers; Chemical and Drug Induced Liver Injury; Cholic Acid; Chromatography, Liquid; Clinical Enzyme Tests; Disease Models, Animal; Enzymes; Glycocholic Acid; Hyperplasia; Liver; Male; Mice; Necrosis; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tandem Mass Spectrometry; Taurocholic Acid | 2014 |
Cardiomyopathy reverses with recovery of liver injury, cholestasis and cholanemia in mouse model of biliary fibrosis.
Topics: Adrenergic beta-Agonists; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biomarkers; Cardiomyopathies; Cholestasis; Cholic Acid; Disease Models, Animal; Drug Resistance; Liver; Liver Cirrhosis, Biliary; Male; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Recovery of Function; Signal Transduction; Time Factors; Ventricular Function, Left | 2015 |
PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis.
Topics: Animals; Apolipoproteins E; Aryldialkylphosphatase; Atherosclerosis; Bile Acids and Salts; Chemokine CCL2; Cholesterol, Dietary; Cholic Acid; Diet; Disease Models, Animal; Female; Gallstones; Gene Expression; Genetic Predisposition to Disease; Inflammation Mediators; Interleukin-6; Intestine, Small; Kidney; Lipid Metabolism; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; Obesity | 2015 |
Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Blood Glucose; Cholestyramine Resin; Cholic Acid; Circadian Rhythm; Cystathionine gamma-Lyase; Diet, High-Fat; Disease Models, Animal; Ethanol; Gene Expression Regulation, Enzymologic; Glucose Intolerance; Hepatocyte Nuclear Factor 3-alpha; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Mice, Knockout; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Time Factors; Transcriptional Activation | 2015 |
Stimulation of apical sodium-dependent bile acid transporter expands the bile acid pool and generates bile acids with positive feedback properties.
Topics: Ampicillin; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cholic Acids; Deoxycholic Acid; Disease Models, Animal; Feedback, Physiological; Humans; Mice; Mice, Knockout; Organic Anion Transporters, Sodium-Dependent; Phenotype; Receptors, Cytoplasmic and Nuclear; Symporters | 2015 |
Loss of keratin 19 favours the development of cholestatic liver disease through decreased ductular reaction.
Topics: Animals; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cholangitis, Sclerosing; Cholestasis, Extrahepatic; Cholic Acid; Choline Deficiency; Common Bile Duct; Disease Models, Animal; Epithelial Cells; Ethionine; Keratin-19; Ligation; Liver; Liver Cirrhosis, Biliary; Liver Regeneration; Male; Mice, Knockout; Phenotype; Pyridines; Signal Transduction; Stem Cells; Time Factors | 2015 |
Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure.
Topics: Animals; Bile Acids and Salts; Blood-Brain Barrier; Central Nervous System Diseases; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Disease Models, Animal; Liver Failure, Acute; Mice, Inbred C57BL; Mice, Knockout; Organic Anion Transporters, Sodium-Dependent; Signal Transduction; Symporters | 2016 |
Hyperlipidemia impairs erectile function in rats by causing cavernosal fibrosis.
Topics: Animals; Apoptosis; Autophagy; Cholesterol, Dietary; Cholic Acid; Collagen; Disease Models, Animal; Electric Stimulation; Erectile Dysfunction; Fibrosis; Hyperlipidemias; In Situ Nick-End Labeling; Lipids; Male; Muscle, Smooth; Penile Erection; Penis; Rats; Rats, Sprague-Dawley | 2017 |
Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid-fed mouse model of cholestasis.
Topics: Animals; Cholestasis; Cholic Acid; Disease Models, Animal; Heterocyclic Compounds, 4 or More Rings; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Sirtuin 1 | 2016 |
Cholic Acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice.
Topics: Animals; Binding Sites; Cholestasis; Cholic Acid; Cytochrome P-450 CYP2D6; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Humans; Liver; Male; Mice; Mice, Transgenic; MicroRNAs; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Messenger | 2017 |
Effective treatment of unconjugated hyperbilirubinemia with oral bile salts in Gunn rats.
Topics: Administration, Oral; Animals; Bile Acids and Salts; Bilirubin; Cholic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Feces; Gastrointestinal Agents; Hyperbilirubinemia; Male; Rats; Tritium; Ursodeoxycholic Acid | 2009 |
Effects of oats on plasma cholesterol and lipoproteins in C57BL/6 mice are substrain specific.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Avena; Cholesterol; Cholic Acid; Diet, Atherogenic; Dietary Fats; Disease Models, Animal; Feces; Female; Genetic Variation; Hypercholesterolemia; Inflammation Mediators; Lipoproteins; Mice; Mice, Inbred C57BL; Plant Preparations; Seeds; Species Specificity | 2010 |
Deficiency of Niemann-Pick C1 protein protects against diet-induced gallstone formation in mice.
Topics: Animals; ATP-Binding Cassette Transporters; Bile; Biological Transport; Cholesterol 7-alpha-Hydroxylase; Cholesterol, Dietary; Cholic Acid; Disease Models, Animal; Gallstones; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Intracellular Signaling Peptides and Proteins; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Niemann-Pick C1 Protein; Proteins; Receptors, LDL; RNA, Messenger; Sterol Regulatory Element Binding Protein 2; Vesicular Transport Proteins | 2010 |
Effect of a hypercholesterolemic diet on serum lipid profile, plasma sex steroid levels, and prostate structure in rats.
Topics: Animals; Cholesterol; Cholesterol, Dietary; Cholic Acid; Disease Models, Animal; Epithelial Cells; Estriol; Hypercholesterolemia; Lipids; Male; Prostate; Prostatic Hyperplasia; Rats; Rats, Wistar; Sex Hormone-Binding Globulin; Testosterone; Triglycerides | 2010 |
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C.
Topics: Animals; B-Lymphocytes; Base Sequence; Cholestasis, Intrahepatic; Cholic Acid; Disease Models, Animal; DNA Primers; Dystocia; Female; Genes, X-Linked; Genetic Diseases, X-Linked; Homozygote; Hyperbilirubinemia, Hereditary; Lymphopenia; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondrial Proton-Translocating ATPases; Molecular Chaperones; Mutation; Phenotype; Pregnancy | 2011 |
The novel Listeria monocytogenes bile sensor BrtA controls expression of the cholic acid efflux pump MdrT.
Topics: Animals; Biological Transport, Active; Cholic Acid; Disease Models, Animal; DNA, Bacterial; Gallbladder; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Listeria monocytogenes; Listeriosis; Membrane Transport Proteins; Mice; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Rodent Diseases; Virulence | 2011 |
Hepatocyte transplantation in bile salt export pump-deficient mice: selective growth advantage of donor hepatocytes under bile acid stress.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Transplantation; Cholestasis, Intrahepatic; Cholic Acid; Disease Models, Animal; Hepatocytes; Liver; Liver Regeneration; Mice; Mice, Mutant Strains; Transplants; Ursodeoxycholic Acid | 2012 |
Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease.
Topics: Animals; Biomarkers; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Common Bile Duct; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Fatty Liver; Gas Chromatography-Mass Spectrometry; Hydroxycholesterols; Ligation; Liver; Liver X Receptors; Male; Non-alcoholic Fatty Liver Disease; Orphan Nuclear Receptors; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; Treatment Outcome | 2012 |
Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats.
Topics: Adipocytes; Animals; Bile Acids and Salts; Body Weight; Cecum; Cholic Acid; Diabetes Mellitus, Type 2; Disease Models, Animal; Eating; Endoplasmic Reticulum Stress; Energy Metabolism; Gammaproteobacteria; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Hepatocytes; Ileum; Insulin; Insulin-Secreting Cells; Lipid Metabolism; Male; Organ Specificity; Rats; Signal Transduction | 2013 |
Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis; Cholic Acid; Disease Models, Animal; Gene Expression Profiling; Hydroxylation; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout | 2003 |
Oncosis represents the main type of cell death in mouse models of cholestasis.
Topics: Animals; Apoptosis; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts; Cell Death; Cell Membrane; Cholestasis; Cholic Acid; Disease Models, Animal; Hepatocytes; Male; Mice | 2005 |
Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium.
Topics: Animals; Barrett Esophagus; Bile Acids and Salts; Blotting, Northern; CDX2 Transcription Factor; Cells, Cultured; Cholic Acid; Disease Models, Animal; Gastrointestinal Contents; Gene Expression Regulation; Genes, Homeobox; Genes, Reporter; Homeodomain Proteins; Humans; Keratinocytes; Male; Promoter Regions, Genetic; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Critical role of cholic acid for development of hypercholesterolemia and gallstones in diabetic mice.
Topics: Alloxan; Animals; Cholesterol, Dietary; Cholic Acid; Diabetes Complications; Disease Models, Animal; Gallstones; Hypercholesterolemia; Male; Mice | 2006 |
Endurance exercise training reduces gallstone development in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Body Weight; Cholestanetriol 26-Monooxygenase; Cholesterol, Dietary; Cholic Acid; Disease Models, Animal; Gallstones; Hydroxymethylglutaryl CoA Reductases; Ileum; Lipoproteins; Liver; Male; Mice; Mice, Inbred C57BL; Physical Endurance; Receptors, LDL; RNA, Messenger; Scavenger Receptors, Class B; Time Factors; Up-Regulation | 2008 |
[Effects of high cholic acid on fetal brains of pregnant rats].
Topics: Animals; Apoptosis; Brain; Cholic Acid; Disease Models, Animal; Female; Fetus; Gravidity; Male; Neurons; Phosphopyruvate Hydratase; Pregnancy; Rats; Rats, Sprague-Dawley | 2007 |
Treatment of the cholesterol biosynthetic defect in Smith-Lemli-Opitz syndrome reproduced in rats by BM 15.766.
Topics: Acyl Coenzyme A; Animals; Cholesterol; Cholic Acid; Cholic Acids; Dehydrocholesterols; Disease Models, Animal; Liver; Lovastatin; Male; Microsomes, Liver; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Piperazines; Rats; Rats, Sprague-Dawley; Smith-Lemli-Opitz Syndrome | 1995 |
[Antioxidant effect of vitamin E in experimental hyperlipidemia].
Topics: Animals; Antioxidants; Cholesterol; Cholic Acid; Cholic Acids; Diet, Atherogenic; Dietary Fats; Disease Models, Animal; Hyperlipidemias; Male; Rats; Rats, Wistar; Vitamin E | 1993 |
Inflammation and a thickened mucus layer in mice with cholesterol gallstones.
Topics: Animals; Cholecystitis; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Cholic Acid; Cholic Acids; Crystallization; Disease Models, Animal; Dogs; Inflammation; Interleukin-1; Mice; Mice, Inbred BALB C; Mucus; Peroxidase | 1998 |
Effects of bile acid depletion and of ursodeoxycholic and chenodeoxycholic acids on biliary protein secretion in the hamster.
Topics: Animals; Bile; Bile Acids and Salts; Biliary Fistula; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chromatography, Gas; Cricetinae; Deoxycholic Acid; Disease Models, Animal; Lithocholic Acid; Male; Mesocricetus; Proteins; Ursodeoxycholic Acid | 1990 |
Cholelithiasis in hamsters: effects of cholic acid and calcium on gallstone formation.
Topics: Animals; Bile; Bile Acids and Salts; Calcium Carbonate; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Cholic Acid; Cholic Acids; Cricetinae; Diet; Disease Models, Animal; Ethinyl Estradiol; Intestinal Absorption; Liver; Male; Mesocricetus; Microscopy, Electron | 1989 |
Endogenous hypertriglyceridemia in a nonobese rat model: plasma lipoproteins and dietary sensitivity.
Topics: Animals; Body Weight; Centrifugation, Zonal; Cholesterol, Dietary; Cholic Acid; Cholic Acids; Diet; Dietary Carbohydrates; Disease Models, Animal; Fructose; Hyperlipoproteinemia Type IV; Isoelectric Focusing; Lipids; Lipoproteins; Male; Polyethylene Glycols; Rats; Rats, Inbred Strains; Rodent Diseases | 1986 |
Ultrastructural changes in gallbladder epithelium of mice under the action of lithogenic diet.
Topics: Animals; Cholelithiasis; Cholesterol, Dietary; Cholic Acid; Cholic Acids; Diet; Disease Models, Animal; Epithelium; Gallbladder; Mice | 1986 |