cholesta-3-5-dien-7-one has been researched along with Alcoholism* in 1 studies
1 other study(ies) available for cholesta-3-5-dien-7-one and Alcoholism
| Article | Year |
|---|---|
Identification of cholesta-3,5-dien-7-one by gas chromatography-mass spectrometry in the erythrocyte membrane of alcoholic patients.
Lipids and oxidized lipids were analyzed by gas chromatography-mass spectrometry in the erythrocyte membranes of alcoholic and control subjects. Cholesta-3,5-dien-7-one and cholesta-trienes were detected in alcoholic samples examined, but not in significant amounts in controls. Levels of polyunsaturated fatty acids (arachidonic acid, 20:4; docosahexaenoic acid, 22:6; and docosatetraenoic acid, 22:4) in alcoholic samples declined significantly, whereas cholesta-3,5-dien-7-one levels increased. A high level of total bilirubin was observed in most patients. A possible mechanism of the accumulation of cholesta-3,5-dien-7-one in the erythrocyte membrane of alcoholics is discussed. Topics: Adult; Alcoholism; Bilirubin; Cholestadienols; Erythrocyte Membrane; Fatty Acids, Nonesterified; Gas Chromatography-Mass Spectrometry; Humans; Lipid Peroxidation; Liver Function Tests; Male; Middle Aged | 1996 |