cholest-5-en-3-one and Nervous-System-Diseases

cholest-5-en-3-one has been researched along with Nervous-System-Diseases* in 1 studies

Other Studies

1 other study(ies) available for cholest-5-en-3-one and Nervous-System-Diseases

Article	Year
CholesteroNitrones for Stroke. Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16 This study describes CholesteroNitrone 2 as an antioxidant and neuroprotective agent against ischemic injury. Neuroprotection was assessed using in vitro and in vivo experimental ischemia models. The compound significantly increased cell viability, induced neuroprotection following ischemic reperfusion, and decreased neurological deficit scores in treated animals, supporting the next preclinical studies as a potential agent for the treatment of stroke. Topics: Animals; Antioxidants; Brain Ischemia; Cell Death; Cells, Cultured; Cholesterol; Ischemic Attack, Transient; Nervous System Diseases; Neurons; Neuroprotective Agents; Nitrogen Oxides; Rats; Reactive Oxygen Species; Reperfusion Injury; Stroke; Structure-Activity Relationship	2015

Article

Year

Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16

This study describes CholesteroNitrone 2 as an antioxidant and neuroprotective agent against ischemic injury. Neuroprotection was assessed using in vitro and in vivo experimental ischemia models. The compound significantly increased cell viability, induced neuroprotection following ischemic reperfusion, and decreased neurological deficit scores in treated animals, supporting the next preclinical studies as a potential agent for the treatment of stroke.

Topics: Animals; Antioxidants; Brain Ischemia; Cell Death; Cells, Cultured; Cholesterol; Ischemic Attack, Transient; Nervous System Diseases; Neurons; Neuroprotective Agents; Nitrogen Oxides; Rats; Reactive Oxygen Species; Reperfusion Injury; Stroke; Structure-Activity Relationship

2015