cholecalciferol and Malocclusion

The abnormal growth of the craniofacial bone leads to skeletal and dental defects, which result in the presence of malocclusions. Not all causes of malocclusion have been explained. In the development of skeletal abnormalities, attention is paid to general deficiencies, including of vitamin D3 (VD3), which causes rickets. Its chronic deficiency may contribute to skeletal malocclusion. The aim of the study was to assess the impact of VD3 deficiency on the development of malocclusions. The examination consisted of a medical interview, oral examination, an alginate impression and radiological imaging, orthodontic assessment, and taking a venous blood sample for VD3 level testing. In about 42.1% of patients, the presence of a skeletal defect was found, and in 46.5% of patients, dentoalveolar malocclusion. The most common defect was transverse constriction of the maxilla with a narrow upper arch (30.7%). The concentration of vitamin 25 (OH) D in the study group was on average 23.6 ± 10.5 (ng/mL). VD3 deficiency was found in 86 subjects (75.4%). Our research showed that VD3 deficiency could be one of an important factor influencing maxillary development. Patients had a greater risk of a narrowed upper arch (OR = 4.94), crowding (OR = 4.94) and crossbite (OR = 6.16). Thus, there was a link between the deficiency of this hormone and the underdevelopment of the maxilla.

Topics: Adolescent; Adult; Cholecalciferol; Female; Humans; Hydroxycholecalciferols; Male; Malocclusion; Maxilla; Middle Aged; Risk Factors; Sunlight; Vitamin D Deficiency; Young Adult

Nutrition plays an important role, especially key vitamins D3 and K2 which are necessary for proper dentofacial development and food consistency influence on crowding and dental arches narrowing. Changes in our dentition and facial appearance are caused by changing our diet from primitive hunter gatherer to a more modern industrialized agriculture. Nutrition and its impact on epigeneticaly- mediated mechanisms continuously shape our phenotype which impacts overall health and can reverse the path for overall health and facial bone development. Orthodontics and nutrition both play a role in following nature's path to reestablishing facial balance and dental arches proportions to accommodate all 32 teeth.

Topics: Adaptation, Physiological; Bone Development; Cholecalciferol; Diet; Epigenesis, Genetic; Facial Bones; Food; Humans; Malocclusion; Maxillofacial Development; Nutritional Physiological Phenomena; Nutritional Status; Nutritive Value; Phenotype; Vitamin K 2; Vitamins

Topics: Age Factors; Child, Preschool; Cholecalciferol; Dental Occlusion; Female; Fingersucking; Follow-Up Studies; Humans; Infant; Male; Malocclusion; Rickets; Tongue Habits