cholecalciferol and Food-Hypersensitivity

Food allergy is now looming as a major health issue with significant implications. In westernized countries, recent reports show a rise in allergic diseases, in particular food allergy. It affects approximately 5-8% of children and 1-5% of adults. Despite this, our current understanding of the immunological and biological mechanisms of food allergy is still incomplete. It is generally believed that food allergy is determined by both genetic and environmental factors. There is some evidence that epigenetic modifications may affect the prevalence of food allergies. This paper discusses the current state of knowledge regarding genetic, epigenetic and environmental factors of food allergy.

Topics: Breast Feeding; Causality; Cholecalciferol; Environmental Exposure; Epigenomics; Filaggrin Proteins; Folic Acid; Food Hypersensitivity; Forkhead Transcription Factors; Gene-Environment Interaction; Humans; Intermediate Filament Proteins; Plants, Genetically Modified; Polymorphism, Genetic; Prevalence; Proteinase Inhibitory Proteins, Secretory; Serine Peptidase Inhibitor Kazal-Type 5; STAT6 Transcription Factor

The importance of sun exposure on human health is well recognized, and a recent trend in the avoidance of sun exposure has led to the risk of missing the beneficial effects such as vitamin D

Topics: Activities of Daily Living; Animals; Antibody Formation; Biomarkers; Cholecalciferol; Cytokines; Diarrhea; Disease Management; Disease Models, Animal; Disease Susceptibility; Dysbiosis; Environmental Exposure; Fecal Microbiota Transplantation; Female; Food Hypersensitivity; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Mice; Oxidative Stress; Phototherapy; Sunlight; T-Lymphocytes