cholecalciferol and Adrenocortical-Hyperfunction

Investigation of 44 patients with endogenous hypercorticism (EH) of various degrees of severity showed that the development of osteoporosis was accompanied by changes in the indices of calcium-phosphorus metabolism and calcium regulating hormones. Marked variations in the level of parathyroidin, calcitonin, vitamin D3 were observed in a severe type of EH. All the examinees were characterized by a decrease in the transport form of vitamin D3, which was most noticeable in a mild form of EH. A significant decrease in the concentration of the transport form of vitamin D3 against a background of hypercalcemia and hypercalciuria in mild EH can be regarded as the most informative indicators in early diagnosis of initial symptoms of osteoporosis.

Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Biological Transport; Calcium; Calcium-Binding Proteins; Cholecalciferol; Combined Modality Therapy; Female; Homeostasis; Humans; Male; Middle Aged; Osteoporosis; Phosphorus