chlorzoxazone has been researched along with Weight Gain in 2 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " By cysteine supplementation (rats with PCMC), some pharmacokinetic parameters restored fully (hepatic microsomal chlorzoxazone 6-hydroxylation activity based on both mg protein and nmol CYP450) or partially (total body clearance and apparent volume of distribution at steady state of CZX, and AUC, terminal half-life and 8-h urinary excretion of OH-CZX) to control levels." | 1.31 | Effects of cysteine on the pharmacokinetics of intravenous chlorzoxazone in rats with protein-calorie malnutrition. ( Cho, MK; Chung, SJ; Kim, SG; Kim, YG; Kwon, JW; Le Myung, G; Shim, CK, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, YG | 1 |
| Cho, MK | 1 |
| Kwon, JW | 1 |
| Kim, SG | 1 |
| Chung, SJ | 1 |
| Shim, CK | 1 |
| Le Myung, G | 1 |
| González-Jasso, E | 1 |
| López, T | 1 |
| Lucas, D | 1 |
| Berthou, F | 1 |
| Manno, M | 1 |
| Ortega, A | 1 |
| Albores, A | 1 |
2 other studies available for chlorzoxazone and Weight Gain
| Article | Year |
|---|---|
Effects of cysteine on the pharmacokinetics of intravenous chlorzoxazone in rats with protein-calorie malnutrition.
Topics: Animals; Area Under Curve; Chlorzoxazone; Cysteine; Eating; Injections, Intravenous; Male; Organ Siz | 2002 |
CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes.
Topics: Acetone; Animals; Benzene; Blotting, Western; Cell Separation; Chlorzoxazone; Cytochrome P-450 CYP2E | 2003 |