chlorzoxazone has been researched along with Spinocerebellar Ataxias in 4 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Spinocerebellar Ataxias: A group of predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marinina, KS | 1 |
| Bezprozvanny, IB | 3 |
| Egorova, PA | 3 |
| Bushart, DD | 1 |
| Huang, H | 1 |
| Man, LJ | 1 |
| Morrison, LM | 1 |
| Shakkottai, VG | 1 |
| Gavrilova, AV | 1 |
| Zakharova, OA | 1 |
| Vlasova, OL | 1 |
4 other studies available for chlorzoxazone and Spinocerebellar Ataxias
| Article | Year |
|---|---|
A chlorzoxazone-folic acid combination improves cognitive affective decline in SCA2-58Q mice.
Topics: Animals; Chlorzoxazone; Cognition; Cognitive Dysfunction; Mice; Mice, Transgenic; Spinocerebellar At | 2023 |
A Chlorzoxazone-Baclofen Combination Improves Cerebellar Impairment in Spinocerebellar Ataxia Type 1.
Topics: Animals; Ataxin-1; Baclofen; Calcium Channels, T-Type; Cerebellum; Chlorzoxazone; Disease Models, An | 2021 |
In vivo analysis of the spontaneous firing of cerebellar Purkinje cells in awake transgenic mice that model spinocerebellar ataxia type 2.
Topics: Action Potentials; Aging; Animals; Cerebellum; Chlorzoxazone; Disease Models, Animal; Injections, In | 2021 |
In vivo analysis of cerebellar Purkinje cell activity in SCA2 transgenic mouse model.
Topics: 1-Naphthylamine; Action Potentials; Aging; Animals; Chlorzoxazone; Disease Models, Animal; Injection | 2016 |