chlorzoxazone has been researched along with Spasm in 12 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to prepare chlorzoxazone orodispersible tablets (ODTs) allowing the drug to directly enter the systemic circulation and bypassing the first-pass metabolism for both enhancing its bioavailability and exerting a rapid relief of muscular spasm." | 3.83 | A pharmaceutical study on chlorzoxazone orodispersible tablets: formulation, in-vitro and in-vivo evaluation. ( El-Nabarawi, MA; ElMeshad, AN; Moqbel, HA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moqbel, HA | 1 |
| ElMeshad, AN | 1 |
| El-Nabarawi, MA | 1 |
| SANDOR, R | 1 |
| BERMAN, HH | 1 |
| NOE, O | 1 |
| GOODFIELD, F | 1 |
| SALA, E | 1 |
| Rosin, MA | 1 |
| Scheiner, JJ | 1 |
| Miller, AR | 1 |
| Hartmann-von Monakow, K | 1 |
| Leszkovszky, GP | 1 |
| Tardos, L | 1 |
| Vernon, WG | 1 |
| Domino, EF | 1 |
| Herman, R | 1 |
3 trials available for chlorzoxazone and Spasm
| Article | Year |
|---|---|
Muscle relaxants: chlorzoxazone compared with diazepam (a double-blind study).
Topics: Adolescent; Adult; Benzoxazoles; Chlorzoxazone; Clinical Trials as Topic; Diazepam; Female; Humans; | 1976 |
A comparative study of Parafon Forte tablets and soma compound in the treatment of painful skeletal muscle conditions.
Topics: Acetaminophen; Adolescent; Adult; Benzoxazoles; Carisoprodol; Chlorzoxazone; Drug Combinations; Fema | 1976 |
A double-blind evaluation of Parafon Forte in the treatment of musculo-skeletal back conditions.
Topics: Acetaminophen; Adolescent; Adult; Back; Benzoxazoles; Bone Diseases; Chlorzoxazone; Clinical Trials | 1972 |
9 other studies available for chlorzoxazone and Spasm
| Article | Year |
|---|---|
A pharmaceutical study on chlorzoxazone orodispersible tablets: formulation, in-vitro and in-vivo evaluation.
Topics: Administration, Oral; Animals; Biological Availability; Chemistry, Pharmaceutical; Chlorzoxazone; Dr | 2016 |
[LOOSENING OF ERECTOR SPASMS BY CHLORZOXAZONE AND ITS EFFECT ON SCIATIC PAIN].
Topics: Back Pain; Cardiovascular Agents; Chlorzoxazone; Humans; Muscle Cramp; Muscle Relaxants, Central; Sc | 1963 |
USE OF CHLORZOXAZONE IN POST MENINGO-ENCEPHALITIC OPISTHOTONIC QUADRIPLEGIA.
Topics: Chlorzoxazone; Encephalitis; Humans; Infant; Meningoencephalitis; Muscle Relaxants, Central; Paralys | 1964 |
[Electrophysiological research on the antispastic activity of chlorzoxazone].
Topics: Chlorzoxazone; Electromyography; Humans; Muscle Spasticity; Paralysis; Research; Spasm; Zoxazolamine | 1962 |
Chlorzoxazone-induced spasmotic torticollis.
Topics: Benzoxazoles; Chlorzoxazone; Female; Humans; Middle Aged; Muscle Cramp; Spasm; Torticollis | 1981 |
[Therapy of spastic syndromes].
Topics: Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Curare; Diazepam; Guaifenesin; Humans; | 1969 |
Pharmacology of a new centrally acting muscle relaxant (RJ-64).
Topics: Animals; Anticonvulsants; Cats; Chlorzoxazone; Interneurons; Mice; Motor Activity; Muscle Contractio | 1970 |
Centrally acting skeletal-muscle relaxants.
Topics: Chemical Phenomena; Chemistry; Chlorzoxazone; Diazepam; Dose-Response Relationship, Drug; Humans; Me | 1974 |
Evaluation of chlorzoxazone on tonic stretch reflex in clinical spasticity.
Topics: Chlorzoxazone; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscles; Spasm | 1967 |