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chlorzoxazone and Nerve Degeneration

chlorzoxazone has been researched along with Nerve Degeneration in 1 studies

Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"Chlorzoxazone (CZ) is a classical FDA-approved drug, and shows anti-inflammatory effects."5.56Chlorzoxazone exhibits neuroprotection against Alzheimer's disease by attenuating neuroinflammation and neurodegeneration in vitro and in vivo. ( Bai, Y; Ma, X, 2020)
"Chlorzoxazone (CZ) is a classical FDA-approved drug, and shows anti-inflammatory effects."1.56Chlorzoxazone exhibits neuroprotection against Alzheimer's disease by attenuating neuroinflammation and neurodegeneration in vitro and in vivo. ( Bai, Y; Ma, X, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Bai, Y1
Ma, X1

Other Studies

1 other study available for chlorzoxazone and Nerve Degeneration

ArticleYear
Chlorzoxazone exhibits neuroprotection against Alzheimer's disease by attenuating neuroinflammation and neurodegeneration in vitro and in vivo.
    International immunopharmacology, 2020, Volume: 88

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Animals; Astrocytes; Behavior, Animal; Cell D

2020