chlorzoxazone has been researched along with Muscle Contraction in 4 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacodynamic analysis offered the results that the dose-normalized biophase levels of CZX were coincident with each other when CZX was given at three different doses under ACH anesthesia at the dose of 80 mg/kg." | 1.28 | Influence of alpha-chloralose on muscle relaxant effect of chlorzoxazone in rats and pharmacodynamic analysis. ( Fukuda, T; Fukumori, Y; Kaneko, I; Takeuchi, Y, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaneko, I | 2 |
| Fukumori, Y | 2 |
| Fukuda, T | 2 |
| Takeuchi, Y | 2 |
| Leszkovszky, GP | 1 |
| Tardos, L | 1 |
| Herman, R | 1 |
4 other studies available for chlorzoxazone and Muscle Contraction
| Article | Year |
|---|---|
Relation of disposition kinetics to pharmacological effect of intravenous administration of chlorzoxazone in rats.
Topics: Animals; Chloralose; Chlorzoxazone; Dose-Response Relationship, Drug; Injections, Intraperitoneal; I | 1990 |
Influence of alpha-chloralose on muscle relaxant effect of chlorzoxazone in rats and pharmacodynamic analysis.
Topics: Animals; Benzoxazoles; Chloralose; Chlorzoxazone; Dose-Response Relationship, Drug; Male; Muscle Con | 1989 |
Pharmacology of a new centrally acting muscle relaxant (RJ-64).
Topics: Animals; Anticonvulsants; Cats; Chlorzoxazone; Interneurons; Mice; Motor Activity; Muscle Contractio | 1970 |
Evaluation of chlorzoxazone on tonic stretch reflex in clinical spasticity.
Topics: Chlorzoxazone; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscles; Spasm | 1967 |