chlorzoxazone has been researched along with Hematologic Malignancies in 1 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzene is a ubiquitous occupational hematotoxin and leukemogen, but people vary in their response to this toxic agent." | 1.30 | Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C-->T mutation and rapid fractional excretion of chlorzoxazone. ( Campleman, S; Dosemeci, M; Hayes, RB; Hoener, B; Li, GL; Linet, M; Lu, W; Meyer, KB; Ross, D; Rothman, N; Smith, MT; Stewart, JT; Titenko-Holland, N; Traver, RD; Wacholder, S; Xi, L; Yin, S; Zhang, L, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rothman, N | 1 |
| Smith, MT | 1 |
| Hayes, RB | 1 |
| Traver, RD | 1 |
| Hoener, B | 1 |
| Campleman, S | 1 |
| Li, GL | 1 |
| Dosemeci, M | 1 |
| Linet, M | 1 |
| Zhang, L | 1 |
| Xi, L | 1 |
| Wacholder, S | 1 |
| Lu, W | 1 |
| Meyer, KB | 1 |
| Titenko-Holland, N | 1 |
| Stewart, JT | 1 |
| Yin, S | 1 |
| Ross, D | 1 |
1 other study available for chlorzoxazone and Hematologic Malignancies
| Article | Year |
|---|---|
Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C-->T mutation and rapid fractional excretion of chlorzoxazone.
Topics: Benzene; Chlorzoxazone; Cohort Studies; Cytochrome P-450 CYP2E1; Hematologic Neoplasms; Humans; Muta | 1997 |