chlorzoxazone has been researched along with Diabetes Mellitus, Type 2 in 3 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gravel, S | 1 |
| Chiasson, JL | 1 |
| Turgeon, J | 1 |
| Grangeon, A | 1 |
| Michaud, V | 1 |
| Wang, Z | 1 |
| Hall, SD | 1 |
| Maya, JF | 1 |
| Li, L | 1 |
| Asghar, A | 1 |
| Gorski, JC | 1 |
| Lucas, D | 1 |
| Farez, C | 1 |
| Bardou, LG | 1 |
| Vaisse, J | 1 |
| Attali, JR | 1 |
| Valensi, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Type 2 Diabetes on CYP450s Activities; Intersubject Variability in Drug Metabolism.[NCT02291666] | Phase 4 | 73 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for chlorzoxazone and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Modulation of CYP450 Activities in Patients With Type 2 Diabetes.
Topics: Adult; Aged; Bupropion; Caffeine; Case-Control Studies; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cyto | 2019 |
Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans.
Topics: Adolescent; Adult; Aged; Chlorzoxazone; Cytochrome P-450 CYP2E1; Diabetes Mellitus, Type 1; Diabetes | 2003 |
Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation.
Topics: Adult; Analysis of Variance; Chlorzoxazone; Cytochrome P-450 CYP2E1; Diabetes Mellitus; Diabetes Mel | 1998 |