chlorzoxazone has been researched along with Conjugate Nystagmus in 2 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pharmacological treatment of cerebellar ataxias and cerebellar nystagmus still remains difficult." | 2.53 | Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus. ( Bremova, T; Feil, K; Muth, C; Schniepp, R; Strupp, M; Teufel, J, 2016) |
| "Chlorzoxazone (CHZ) is a nonselective activator of small conductance calcium-activated potassium (SK) channels that modifies the activity of cerebellar Purkinje cells." | 1.39 | Effect of chlorzoxazone in patients with downbeat nystagmus: a pilot trial. ( Bardins, S; Claaßen, J; Feil, K; Jahn, K; Kalla, R; Krafczyk, S; Schneider, E; Schniepp, R; Strupp, M; Teufel, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feil, K | 2 |
| Claaßen, J | 1 |
| Bardins, S | 1 |
| Teufel, J | 2 |
| Krafczyk, S | 1 |
| Schneider, E | 1 |
| Schniepp, R | 2 |
| Jahn, K | 1 |
| Kalla, R | 1 |
| Strupp, M | 2 |
| Bremova, T | 1 |
| Muth, C | 1 |
1 review available for chlorzoxazone and Conjugate Nystagmus
| Article | Year |
|---|---|
Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus.
Topics: 4-Aminopyridine; Cerebellar Ataxia; Chlorzoxazone; Drug Therapy; Humans; Leucine; Muscle Relaxants, | 2016 |
1 other study available for chlorzoxazone and Conjugate Nystagmus
| Article | Year |
|---|---|
Effect of chlorzoxazone in patients with downbeat nystagmus: a pilot trial.
Topics: Aged; Chi-Square Distribution; Chlorzoxazone; Eye Movements; Female; Follow-Up Studies; Humans; Male | 2013 |