Page last updated: 2024-10-25

chlorzoxazone and Chronic Pain

chlorzoxazone has been researched along with Chronic Pain in 1 studies

Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.

Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.

Research Excerpts

ExcerptRelevanceReference
"In study IV we hypothesized that intraoperative ketamine would reduce postoperative opioid consumption and persistent pain after spinal fusion surgery in chronic pain patients with opioid dependency."4.98Adjuvant analgesics for spine surgery. ( Nielsen, RV, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nielsen, RV1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery: A Randomized, Double-blind Trial[NCT06062550]Phase 4312 participants (Anticipated)Interventional2023-10-31Not yet recruiting
Impact of Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia on Long-term Outcomes After Scoliosis Correction Surgery: Follow-up of a Randomized Trial[NCT06087510]Phase 4312 participants (Anticipated)Interventional2024-01-31Not yet recruiting
Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Patient-controlled Analgesia After Scoliosis Correction Surgery: a Randomized, Double-blind, Placebo-controlled Trial[NCT04791059]Phase 4200 participants (Actual)Interventional2021-04-09Completed
Effect of Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia on Long-term Outcomes Following Scoliosis Correction Surgery: 2-year Follow-up of a Randomized Controlled Trial[NCT05718544]Phase 4199 participants (Actual)Interventional2023-01-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for chlorzoxazone and Chronic Pain

ArticleYear
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018
Adjuvant analgesics for spine surgery.
    Danish medical journal, 2018, Volume: 65, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Chlorzoxazone; Chronic Pain; Dexamethasone; Humans; Intraoperative Pe

2018