chlorzoxazone has been researched along with Cerebellar Ataxia in 4 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pharmacological treatment of cerebellar ataxias and cerebellar nystagmus still remains difficult." | 2.53 | Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus. ( Bremova, T; Feil, K; Muth, C; Schniepp, R; Strupp, M; Teufel, J, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feil, K | 1 |
| Bremova, T | 1 |
| Muth, C | 1 |
| Schniepp, R | 1 |
| Teufel, J | 1 |
| Strupp, M | 1 |
| Alviña, K | 2 |
| Khodakhah, K | 2 |
| Gao, Z | 1 |
| Todorov, B | 1 |
| Barrett, CF | 1 |
| van Dorp, S | 1 |
| Ferrari, MD | 1 |
| van den Maagdenberg, AM | 1 |
| De Zeeuw, CI | 1 |
| Hoebeek, FE | 1 |
1 review available for chlorzoxazone and Cerebellar Ataxia
| Article | Year |
|---|---|
Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus.
Topics: 4-Aminopyridine; Cerebellar Ataxia; Chlorzoxazone; Drug Therapy; Humans; Leucine; Muscle Relaxants, | 2016 |
3 other studies available for chlorzoxazone and Cerebellar Ataxia
| Article | Year |
|---|---|
KCa channels as therapeutic targets in episodic ataxia type-2.
Topics: Analysis of Variance; Animals; Benzimidazoles; Cerebellar Ataxia; Cerebellum; Chlorzoxazone; Disease | 2010 |
The therapeutic mode of action of 4-aminopyridine in cerebellar ataxia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Behavior, Animal; Cerebellar Ataxia; | 2010 |
Cerebellar ataxia by enhanced Ca(V)2.1 currents is alleviated by Ca2+-dependent K+-channel activators in Cacna1a(S218L) mutant mice.
Topics: Action Potentials; Animals; Behavior, Animal; Benzimidazoles; Calcium; Calcium Channels, N-Type; Cal | 2012 |