Page last updated: 2024-10-25

chlorzoxazone and Aging

chlorzoxazone has been researched along with Aging in 7 studies

Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Egorova, PA2
Gavrilova, AV1
Bezprozvanny, IB2
Zakharova, OA1
Vlasova, OL1
Wauthier, V2
Verbeeck, RK2
Buc Calderon, P1
Warrington, JS1
Court, MH1
Greenblatt, DJ1
von Moltke, LL1
Schenten, V1
Calderon, PB1
Alcorn, J1
Elbarbry, FA1
Allouh, MZ1
McNamara, PJ1
Vieira, I1
Sonnier, M1
Cresteil, T1

Other Studies

7 other studies available for chlorzoxazone and Aging

ArticleYear
In vivo analysis of the spontaneous firing of cerebellar Purkinje cells in awake transgenic mice that model spinocerebellar ataxia type 2.
    Cell calcium, 2021, Volume: 93

    Topics: Action Potentials; Aging; Animals; Cerebellum; Chlorzoxazone; Disease Models, Animal; Injections, In

2021
In vivo analysis of cerebellar Purkinje cell activity in SCA2 transgenic mouse model.
    Journal of neurophysiology, 2016, 06-01, Volume: 115, Issue:6

    Topics: 1-Naphthylamine; Action Potentials; Aging; Animals; Chlorzoxazone; Disease Models, Animal; Injection

2016
Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?
    Archives of toxicology, 2004, Volume: 78, Issue:3

    Topics: Age Factors; Aging; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Chlorzoxazone; Cytoch

2004
Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:6

    Topics: Aging; Animals; Biotransformation; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P

2004
Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats.
    Life sciences, 2006, Oct-12, Volume: 79, Issue:20

    Topics: Aging; Animals; Chlorzoxazone; Cytochrome P-450 CYP2E1; Down-Regulation; Gene Expression Regulation,

2006
Evaluation of the assumptions of an ontogeny model of rat hepatic cytochrome P450 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:12

    Topics: Age Factors; Aging; Animals; Body Weight; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 C

2007
Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period.
    European journal of biochemistry, 1996, Jun-01, Volume: 238, Issue:2

    Topics: Adult; Aging; Base Sequence; Blotting, Southern; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome

1996