chlorthalidone has been researched along with Weight Loss in 8 studies
Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
Weight Loss: Decrease in existing BODY WEIGHT.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To assess whether chlorthalidone affected levels of putatively atherogenic small, dense LDL (LDL 3), we conducted a 12 week double blind randomized, placebo controlled clinical trial in 34 nonsmoking men aged 35 to 57 years with mild hypertension (DBP 90 to 104 mm Hg)." | 9.07 | Chlorthalidone attenuates the reduction in total cholesterol and small, dense LDL cholesterol subclass associated with weight loss. ( Belcher, J; Bradley, K; Elmer, P; Flack, JM; Grimm, R; Miller, P, 1993) |
| " They were randomized to a usual diet (n = 296) or to a weight loss diet (n = 291) and within each diet group to placebo, chlorthalidone, 25 mg/d, or atenolol, 50 mg/d." | 5.07 | Reduction in long-term antihypertensive medication requirements. Effects of weight reduction by dietary intervention in overweight persons with mild hypertension. ( Blaufox, MD; Cutler, JA; Davis, BR; Kirchner, K; Langford, HG; Oberman, A; Wassertheil-Smoller, S; Zimbaldi, N, 1993) |
| " To assess whether chlorthalidone affected levels of putatively atherogenic small, dense LDL (LDL 3), we conducted a 12 week double blind randomized, placebo controlled clinical trial in 34 nonsmoking men aged 35 to 57 years with mild hypertension (DBP 90 to 104 mm Hg)." | 5.07 | Chlorthalidone attenuates the reduction in total cholesterol and small, dense LDL cholesterol subclass associated with weight loss. ( Belcher, J; Bradley, K; Elmer, P; Flack, JM; Grimm, R; Miller, P, 1993) |
| "Subjects were randomly assigned to usual, weight loss, or low sodium/high potassium diet and then randomly assigned to receive placebo, chlorthalidone, or atenolol." | 5.07 | Renin predicts diastolic blood pressure response to nonpharmacologic and pharmacologic therapy. ( Blaufox, MD; Davis, B; Langford, H; Lee, HB; Oberman, A; Wassertheil-Smoller, S, 1992) |
| " The Trial of Antihypertensive Interventions and Management studied 878 mildly hypertensive individuals randomly assigned, in a 3 x 3 design, to no diet change, weight loss, or a low sodium-high potassium diet and to placebo, 25 mg chlorthalidone, or 50 mg atenolol." | 5.07 | Effect of antihypertensive therapy on weight loss. The Trial of Antihypertensive Interventions and Management Research Group. ( Blaufox, MD; Cutler, JA; Davis, BR; Hawkins, CM; Langford, HG; Oberman, A; Wassertheil-Smoller, S; Zimbaldi, N, 1992) |
| "This report examines the effect of weight loss, alone and in combination with drugs, on diastolic blood pressure change in the Trial of Antihypertensive Interventions and Management (TAIM), which is a randomized, multicenter, placebo-controlled clinical trial of drug and diet combinations in the treatment of mild hypertension among 787 patients." | 2.67 | The Trial of Antihypertensive Interventions and Management (TAIM) study. Adequate weight loss, alone and combined with drug therapy in the treatment of mild hypertension. ( Blaufox, MD; Davis, BR; Langford, HG; Oberman, AS; Wassertheil-Smoller, S; Wylie-Rosett, J, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CAMPSCARDONA, J | 1 |
| Davis, BR | 3 |
| Blaufox, MD | 5 |
| Oberman, A | 4 |
| Wassertheil-Smoller, S | 5 |
| Zimbaldi, N | 2 |
| Cutler, JA | 2 |
| Kirchner, K | 1 |
| Langford, HG | 3 |
| Bradley, K | 1 |
| Flack, JM | 1 |
| Belcher, J | 1 |
| Elmer, P | 1 |
| Miller, P | 1 |
| Grimm, R | 1 |
| Lee, HB | 1 |
| Davis, B | 2 |
| Langford, H | 2 |
| Hawkins, CM | 1 |
| Oberman, AS | 1 |
| Wylie-Rosett, J | 1 |
| Kaplan, NM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000513] | Phase 3 | 0 participants | Interventional | 1984-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for chlorthalidone and Weight Loss
| Article | Year |
|---|---|
Reduction in long-term antihypertensive medication requirements. Effects of weight reduction by dietary intervention in overweight persons with mild hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Chlorthalidone; Female; Humans; Hypertension; Male; | 1993 |
Chlorthalidone attenuates the reduction in total cholesterol and small, dense LDL cholesterol subclass associated with weight loss.
Topics: Adult; Chlorthalidone; Cholesterol; Cholesterol, LDL; Double-Blind Method; Humans; Hypertension; Mal | 1993 |
Renin predicts diastolic blood pressure response to nonpharmacologic and pharmacologic therapy.
Topics: Adult; Aged; Atenolol; Chlorthalidone; Diastole; Humans; Hypertension; Middle Aged; Regression Analy | 1992 |
Effect of antihypertensive therapy on weight loss. The Trial of Antihypertensive Interventions and Management Research Group.
Topics: Atenolol; Chlorthalidone; Combined Modality Therapy; Energy Intake; Exercise; Female; Humans; Hypert | 1992 |
The Trial of Antihypertensive Interventions and Management (TAIM) study. Adequate weight loss, alone and combined with drug therapy in the treatment of mild hypertension.
Topics: Atenolol; Black People; Body Mass Index; Chlorthalidone; Combined Modality Therapy; Female; Humans; | 1992 |
The Trial of Antihypertensive Interventions and Management (TAIM) Study. Final results with regard to blood pressure, cardiovascular risk, and quality of life.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Body Weight; Cardiovascular Diseases | 1992 |
Commentary on the Trial of Antihypertensive Interventions and Management (TAIM) Study.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Female; Humans; Hype | 1992 |
1 other study available for chlorthalidone and Weight Loss
| Article | Year |
|---|---|
[WATER DEPLETION IN WEIGHT REDUCTION. CLINICAL EXPERIENCE WITH G 33182 (HYGROTON)].
Topics: Chlorthalidone; Drug Therapy; Obesity; Water; Weight Loss | 1964 |