Compounds > chlorthalidone
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chlorthalidone and Potassium Deficiency

chlorthalidone has been researched along with Potassium Deficiency in 7 studies

Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.

Potassium Deficiency: A condition due to decreased dietary intake of potassium, as in starvation or failure to administer in intravenous solutions, or to gastrointestinal loss in diarrhea, chronic laxative abuse, vomiting, gastric suction, or bowel diversion. Severe potassium deficiency may produce muscular weakness and lead to paralysis and respiratory failure. Muscular malfunction may result in hypoventilation, paralytic ileus, hypotension, muscle twitches, tetany, and rhabomyolysis. Nephropathy from potassium deficit impairs the concentrating mechanism, producing POLYURIA and decreased maximal urinary concentrating ability with secondary POLYDIPSIA. (Merck Manual, 16th ed)

Research Excerpts

ExcerptRelevanceReference
" Triamterene seemed ineffective in the dosage used (50 mg twice daily)."2.64Potassium-sparing agents during diuretic therapy in hypertension. ( Brien, TG; Canning, BS; Donohoe, JF; Healy, JJ; McKenna, TJ; Muldowney, FP, 1971)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
EARLEY, LE1
ORLOFF, J1
EDLEN, A1
Tarpley, EL1
Berg, KJ1
Gisholt, K1
Wideroe, TE1
McKenna, TJ1
Donohoe, JF1
Brien, TG1
Healy, JJ1
Canning, BS1
Muldowney, FP1

Reviews

1 review available for chlorthalidone and Potassium Deficiency

ArticleYear
THIAZIDE DIURETICS.
    Annual review of medicine, 1964, Volume: 15

    Topics: Antihypertensive Agents; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Diabetes Insipidus; Diur

1964

Trials

2 trials available for chlorthalidone and Potassium Deficiency

ArticleYear
Controlled-release potassium supplementation.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:7

    Topics: Adult; Blood Pressure; Chlorides; Chlorothiazide; Chlorthalidone; Clinical Trials as Topic; Delayed-

1974
Potassium-sparing agents during diuretic therapy in hypertension.
    British medical journal, 1971, Jun-26, Volume: 2, Issue:5764

    Topics: Adult; Aged; Chlorthalidone; Diuretics; Humans; Hypertension; Middle Aged; Potassium; Potassium Defi

1971

Other Studies

4 other studies available for chlorthalidone and Potassium Deficiency

ArticleYear
Blood pressure drugs may raise the risk of adult diabetes. Potassium loss caused by hypertension drugs could place patients in the type 2 diabetes danger zone.
    DukeMedicine healthnews, 2009, Volume: 15, Issue:3

    Topics: Aged; Antihypertensive Agents; Chlorthalidone; Controlled Clinical Trials as Topic; Diabetes Mellitu

2009
[IATROGENIC KALIPENIA].
    Svenska lakartidningen, 1964, Aug-12, Volume: 61

    Topics: Chlorthalidone; Diuretics; Electrocardiography; Humans; Hypokalemia; Iatrogenic Disease; Potassium;

1964
Potassium deficiency in hypertensives treated with diuretics. Analysis of three alternative treatments by an oral test for potassium deficiency.
    European journal of clinical pharmacology, 1974, Oct-04, Volume: 7, Issue:6

    Topics: Adult; Aged; Chlorthalidone; Diuretics; Female; Humans; Hypertension; Male; Potassium; Potassium Def

1974
Hypotensive drugs. II. General considerations.
    British medical journal, 1969, May-17, Volume: 2, Issue:5654

    Topics: Adult; Aged; Chlorthalidone; Diuretics; Female; Guanethidine; Humans; Hypertension; Male; Methyldopa

1969