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chlorthalidone and Kidney Stones

chlorthalidone has been researched along with Kidney Stones in 17 studies

Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.

Research Excerpts

ExcerptRelevanceReference
" Our data show that CTL is associated with greater reduction in 24 h UCa compared to similarly dosed HCTZ."5.39Hydrochlorothiazide compared to chlorthalidone in reduction of urinary calcium in patients with kidney stones. ( Astor, BC; Gundu, V; Jhagroo, RA; Wolfgram, DF, 2013)
"We examined the effectiveness of chlorthalidone or magnesium hydroxide in the prevention of recurrent calcium oxalate kidney calculi."5.06Chlorthalidone reduces calcium oxalate calculous recurrence but magnesium hydroxide does not. ( Citron, JT; Dolman, LI; Ettinger, B; Livermore, B, 1988)
"A 60-year-old woman who had been instructed to increase her water intake because of nephrolithiasis developed the syndrome of inappropriate secretion of antidiuretic hormone when treated with chlorthalidone for mild hypertension."3.66Chlorthalidone-induced syndrome of inappropriate secretion of antidiuretic hormone. ( Barzilai, D; Luboshitzky, R; Tal-Or, Z, 1978)
"Thiazides are considered to be effective in preventing recurrence of various types of nephrolithiasis, but the optimum dosage has not been established."2.66[Optimal dosage of chlorthalidone in the prevention of the recurrence of nephrolithiasis is 25 mg per day]. ( Bugnon, JM; Burckhardt, P; Jacquet, AF; Jaeger, P; Portmann, L, 1986)
"Struvite stones have been associated with significant morbidity and mortality, yet there has not been a report on the medical management of struvite stones in almost 20 years."1.43Contemporary Management of Struvite Stones Using Combined Endourologic and Medical Treatment: Predictors of Unfavorable Clinical Outcome. ( Ferrandino, MN; Hanna, J; Iqbal, MW; Kuntz, N; Lipkin, ME; Neisius, A; Preminger, GM; Youssef, RF, 2016)
" Our data show that CTL is associated with greater reduction in 24 h UCa compared to similarly dosed HCTZ."1.39Hydrochlorothiazide compared to chlorthalidone in reduction of urinary calcium in patients with kidney stones. ( Astor, BC; Gundu, V; Jhagroo, RA; Wolfgram, DF, 2013)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's5 (29.41)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Krieger, NS2
Asplin, J2
Granja, I2
Chen, L2
Spataru, D1
Wu, TT2
Grynpas, M2
Bushinsky, DA4
Asplin, JR2
Ramos, FM1
Flotteron, C1
Grynpas, MD1
Wolfgram, DF1
Gundu, V1
Astor, BC1
Jhagroo, RA1
Iqbal, MW1
Youssef, RF1
Neisius, A1
Kuntz, N1
Hanna, J1
Ferrandino, MN1
Preminger, GM1
Lipkin, ME1
Vigen, R1
Weideman, RA1
Reilly, RF1
Willett, T1
Culbertson, C1
Che, SP1
Raja, KA1
Schurman, S1
D'mello, RG1
Blowey, D1
Goodyer, P1
Van Why, S1
Ploutz-Snyder, RJ1
Scheinman, SJ1
Evans, RA1
Hills, E1
Wong, SY1
Wyndham, LE1
Eade, Y1
Dunstan, CR1
Weber, DV1
Coe, FL2
Parks, JH2
Dunn, MS1
Tembe, V1
Lockefeer, JH1
Juttmann, JR1
Birkenhäger, JC2
Luboshitzky, R1
Tal-Or, Z1
Barzilai, D1
Ettinger, B1
Citron, JT1
Livermore, B1
Dolman, LI1
Langman, CB1
Favus, MJ1
Jaeger, P1
Portmann, L1
Jacquet, AF1
Bugnon, JM1
Burckhardt, P1
Lockefeer, J1
Bakker, NJ1
Gursel, E1

Trials

4 trials available for chlorthalidone and Kidney Stones

ArticleYear
Responsiveness of hypercalciuria to thiazide in Dent's disease.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:12

    Topics: Adolescent; Adult; Amiloride; Calcium; Calcium Oxalate; Child; Chlorthalidone; Chromosomes, Human, X

2002
Chlorthalidone reduces calcium oxalate calculous recurrence but magnesium hydroxide does not.
    The Journal of urology, 1988, Volume: 139, Issue:4

    Topics: Calcium Oxalate; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Kidn

1988
Chlorthalidone promotes mineral retention in patients with idiopathic hypercalciuria.
    Kidney international, 1988, Volume: 33, Issue:6

    Topics: Adult; Calcium; Calcium Oxalate; Chlorthalidone; Female; Humans; Kidney Calculi; Male; Middle Aged;

1988
[Optimal dosage of chlorthalidone in the prevention of the recurrence of nephrolithiasis is 25 mg per day].
    Schweizerische medizinische Wochenschrift, 1986, Mar-08, Volume: 116, Issue:10

    Topics: Calcium; Chlorthalidone; Crystallization; Dose-Response Relationship, Drug; Humans; Kidney Calculi;

1986

Other Studies

13 other studies available for chlorthalidone and Kidney Stones

ArticleYear
Chlorthalidone with potassium citrate decreases calcium oxalate stones and increases bone quality in genetic hypercalciuric stone-forming rats.
    Kidney international, 2021, Volume: 99, Issue:5

    Topics: Animals; Calcium; Calcium Oxalate; Chlorthalidone; Hypercalciuria; Kidney Calculi; Potassium Citrate

2021
Chlorthalidone Is Superior to Potassium Citrate in Reducing Calcium Phosphate Stones and Increasing Bone Quality in Hypercalciuric Stone-Forming Rats.
    Journal of the American Society of Nephrology : JASN, 2019, Volume: 30, Issue:7

    Topics: Animals; Bone Density; Calcium Phosphates; Chlorthalidone; Hypercalciuria; Kidney Calculi; Male; Oxa

2019
Hydrochlorothiazide compared to chlorthalidone in reduction of urinary calcium in patients with kidney stones.
    Urolithiasis, 2013, Volume: 41, Issue:4

    Topics: Calcium; Chlorthalidone; Diuretics; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middl

2013
Contemporary Management of Struvite Stones Using Combined Endourologic and Medical Treatment: Predictors of Unfavorable Clinical Outcome.
    Journal of endourology, 2016, Volume: 30, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Calcium Citrate; Chlorthalidone; Comorbidity;

2016
Thiazides diuretics in the treatment of nephrolithiasis: are we using them in an evidence-based fashion?
    International urology and nephrology, 2011, Volume: 43, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Chi-Square Distribution; Chlorthalidone; Dose-

2011
Chlorthalidone improves vertebral bone quality in genetic hypercalciuric stone-forming rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, Volume: 26, Issue:8

    Topics: Animals; Biomechanical Phenomena; Bone Density; Calcification, Physiologic; Calcium Oxalate; Calcium

2011
Do thiazides prevent recurrent idiopathic renal calcium stones.
    Lancet (London, England), 1981, Sep-12, Volume: 2, Issue:8246

    Topics: Calcium; Chlorthalidone; Female; Humans; Kidney Calculi; Male; Recurrence

1981
The pathogenesis of idiopathic hypercalciuria: evidence for parathyroid hyperfunction.
    The Quarterly journal of medicine, 1984,Winter, Volume: 53, Issue:209

    Topics: Adult; Aged; Calcium; Chlorthalidone; Cyclic AMP; Fasting; Female; Humans; Hyperparathyroidism; Kidn

1984
Urinary saturation measurements in calcium nephrolithiasis.
    Annals of internal medicine, 1979, Volume: 90, Issue:2

    Topics: Calcium; Calcium Oxalate; Chlorthalidone; Female; Humans; Kidney Calculi; Male; Time Factors; Trichl

1979
The effect of long-term chlorthalidone on stone formation and stone growth, intestinal absorption of calcium and secretion of parathyroid hormone in idiopathic hypercalciuria.
    The Netherlands journal of medicine, 1977, Volume: 20, Issue:6

    Topics: Adult; Calcium; Chlorthalidone; Female; Humans; Intestinal Absorption; Intestinal Mucosa; Kidney Cal

1977
Chlorthalidone-induced syndrome of inappropriate secretion of antidiuretic hormone.
    Journal of clinical pharmacology, 1978, Volume: 18, Issue:7

    Topics: Chlorthalidone; Female; Humans; Hypertension; Kidney Calculi; Osmolar Concentration; Sodium; Time Fa

1978
[Diuretic treatment of recurrent nephrolithiasis caused by idiopathic hypercalciuria].
    Nederlands tijdschrift voor geneeskunde, 1972, Aug-12, Volume: 116, Issue:33

    Topics: Calcium; Calcium Metabolism Disorders; Chlorthalidone; Humans; Kidney Calculi; Recurrence

1972
Effects of diuretics on renal and intestinal handling of calcium.
    New York state journal of medicine, 1970, Feb-01, Volume: 70, Issue:3

    Topics: Aged; Calcium; Calcium, Dietary; Chlorthalidone; Female; Humans; Intestinal Absorption; Kidney Calcu

1970