chlorthalidone has been researched along with Hyperkalemia in 6 studies
Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Enablement of more persistent spironolactone use with newer potassium-binding agents, the clinical development of novel nonsteroidal MRAs with a more favourable benefit-risk profile and the recently proven blood pressure lowering action of chlorthalidone are three therapeutic opportunities for more effective management of hypertension in high-risk patients with advanced CKD." | 5.22 | Management of hypertension in advanced kidney disease. ( Agarwal, R; Georgianos, PI, 2022) |
| "For patients with treatment-resistant hypertension, guidelines recommend the addition of spironolactone to the baseline antihypertensive regimen." | 3.01 | Hypertension in chronic kidney disease-treatment standard 2023. ( Agarwal, R; Georgianos, PI, 2023) |
| "Hyperkalemia was associated with increased risk of combined cardiovascular disease (hazard ratio, 1." | 2.77 | Clinical significance of incident hypokalemia and hyperkalemia in treated hypertensive patients in the antihypertensive and lipid-lowering treatment to prevent heart attack trial. ( Alderman, MH; Calhoun, DA; Cushman, WC; Davis, BR; Eckfeldt, JH; Einhorn, PT; Ford, CE; Franklin, SS; Furberg, CD; Ong, ST; Oparil, S; Papademetriou, V; Piller, LB; Probstfield, JL, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Georgianos, PI | 2 |
| Agarwal, R | 2 |
| Alderman, MH | 1 |
| Piller, LB | 1 |
| Ford, CE | 1 |
| Probstfield, JL | 1 |
| Oparil, S | 1 |
| Cushman, WC | 1 |
| Einhorn, PT | 1 |
| Franklin, SS | 1 |
| Papademetriou, V | 1 |
| Ong, ST | 1 |
| Eckfeldt, JH | 1 |
| Furberg, CD | 1 |
| Calhoun, DA | 1 |
| Davis, BR | 1 |
| Gray, JM | 1 |
| Lawson, DH | 1 |
| Boddy, K | 1 |
| East, W | 1 |
| Fortini, A | 1 |
| Nenci, G | 1 |
| Laureano, R | 1 |
| Cappelletti, C | 1 |
| Leiter, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for chlorthalidone and Hyperkalemia
| Article | Year |
|---|---|
Management of hypertension in advanced kidney disease.
Topics: Blood Pressure; Chlorthalidone; Humans; Hyperkalemia; Hypertension; Mineralocorticoid Receptor Antag | 2022 |
Hypertension in chronic kidney disease-treatment standard 2023.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hyperkalemia; Hypertension; Mineral | 2023 |
Combinations of diuretics in the treatment of edema.
Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu | 1970 |
1 trial available for chlorthalidone and Hyperkalemia
| Article | Year |
|---|---|
Clinical significance of incident hypokalemia and hyperkalemia in treated hypertensive patients in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Chemical Analysis; Cardiovascular Diseases; Chlorth | 2012 |
2 other studies available for chlorthalidone and Hyperkalemia
| Article | Year |
|---|---|
Total body potassium in patients receiving chlorthalidone and metoprolol for hypertension.
Topics: Adult; Chlorthalidone; Female; Humans; Hyperkalemia; Hypertension; Male; Metoprolol; Middle Aged; Po | 1983 |
[Hypertension, hyperpotassemia and normal glomerular filtration (Gordon's syndrome): a case report].
Topics: Adult; Antihypertensive Agents; Chlorthalidone; Diuretics; Electrocardiography, Ambulatory; Glomerul | 1996 |