chlorthalidone and Heart Failure studies

Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

Excerpt	Relevance	Reference
"In older persons with isolated systolic hypertension, stepped-care treatment based on low-dose chlorthalidone exerted a strong protective effect in preventing heart failure."	5.08	Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research Group. ( Applegate, WB; Berge, KG; Berkson, DM; Black, HR; Blaufox, MD; Cohen, JD; Curb, JD; Cutler, J; Davis, BR; Grimm, RH; Kostis, JB; Lacy, CR; McDonald, R; Perry, HM; Schron, E; Smith, WM; Wassertheil-Smoller, S, 1997)
"There is significant controversy around whether chlorthalidone (CTD) is superior to hydrochlorothiazide (HCTZ) in hypertension management."	3.77	Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis. ( Bleske, BE; Dorsch, MP; Erickson, SR; Gillespie, BW; Weder, AB, 2011)
"Background Hypertension is a known risk factor for heart failure ( HF ), possibly via the mechanism of cardiac remodeling and left ventricular hypertrophy ( LVH )."	2.90	Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. ( Davis, BR; Johnson, K; Oparil, S; Tereshchenko, LG, 2019)
"Chlorthalidone was superior to (1) doxazosin mesylate in preventing combined CVD (CCVD) (risk ratio [RR], 1."	2.74	ALLHAT findings revisited in the context of subsequent analyses, other trials, and meta-analyses. ( Alderman, MH; Black, HR; Cushman, WC; Cutler, JA; Davis, BR; Einhorn, PT; Ford, CE; Haywood, LJ; Margolis, KL; Oparil, S; Pressel, SL; Probstfield, JL; Rahman, M; Whelton, PK; Wright, JT, 2009)
"Hypertension is a major cause of heart failure (HF) and is antecedent in 91% of cases."	2.72	Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. ( Colon, P; Crow, R; Cutler, JA; Davis, BR; Dunn, K; Ellsworth, A; Franklin, S; Furberg, C; Goff, D; Golden, J; Leenen, F; Mohiuddin, S; Papademetriou, V; Piller, LB; Proschan, M, 2006)
"The doxazosin arm was terminated early, when the trial's safety and monitoring board noted a twofold higher incidence of congestive heart failure in patients receiving doxazosin than in those receiving chlorthalidone (8."	1.31	Alpha-blockers and congestive heart failure: early termination of an arm of the ALLHAT trial. ( Vidt, DG, 2000)
"Type 2 diabetes is increasing in prevalence and is predominantly managed in general practice."	1.30	A cautionary tale. ( Phillips, PJ; Popplewell, PY; Tallis, GA, 1997)
"Treatment with triamterene (100 mg/d; n = 10) over a period of 3 weeks led to an increase of serum potassium (from 4."	1.26	[Serum and total body potassium during treatment with chlortalidone and hydrochlorothiazide. Influence of triamterene (author's transl)]. ( Kaltenbach, M; Kober, G; Schäfer, GE; Werner, E, 1977)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (57.75)	18.7374
1990's	3 (4.23)	18.2507
2000's	12 (16.90)	29.6817
2010's	11 (15.49)	24.3611
2020's	4 (5.63)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
[NCT00000542]	Phase 3	0 participants	Interventional	1993-08-31	Completed
Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055]	Phase 4	75 participants (Anticipated)	Interventional	2023-08-25	Recruiting
Pharmacological Association of the Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism on Blood Pressure and Cardiovascular Risk in Relation to Anti-hypertensive Treatment[NCT00006294]		37,939 participants (Actual)	Observational	1999-09-30	Completed
[NCT00000514]	Phase 3	0 participants	Interventional	1984-06-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs--overview and meta-analyses. Journal of hypertension, 2015, Volume: 33, Issue:2 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit	2015
Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs--overview and meta-analyses. Journal of hypertension, 2015, Volume: 33, Issue:2 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit	2015
ALLHAT: still providing correct answers after 7 years. Current opinion in cardiology, 2010, Volume: 25, Issue:4 Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bla	2010
ALLHAT: still providing correct answers after 7 years. Current opinion in cardiology, 2010, Volume: 25, Issue:4 Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bla	2010
MANAGEMENT OF RENAL DYSFUNCTION IN CONGESTIVE HEART FAILURE. Biochemical clinics, 1963, Volume: 2 Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Heart Failure; Humans; Kidney Diseases;	1963
MANAGEMENT OF RENAL DYSFUNCTION IN CONGESTIVE HEART FAILURE. Biochemical clinics, 1963, Volume: 2 Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Heart Failure; Humans; Kidney Diseases;	1963
[The clinical usefulness of diuretics for chronic heart failure in ALLHAT]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Apr-28, Volume: 65 Suppl 4 Topics: Chlorthalidone; Clinical Trials as Topic; Diuretics; Heart Failure; Humans	2007
[The clinical usefulness of diuretics for chronic heart failure in ALLHAT]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Apr-28, Volume: 65 Suppl 4 Topics: Chlorthalidone; Clinical Trials as Topic; Diuretics; Heart Failure; Humans	2007
Combinations of diuretics in the treatment of edema. American heart journal, 1970, Volume: 80, Issue:3 Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu	1970
Combinations of diuretics in the treatment of edema. American heart journal, 1970, Volume: 80, Issue:3 Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu	1970

Article	Year
Diuretic Strategies in Acute Heart Failure and Renal Dysfunction: Conventional vs Carbohydrate Antigen 125-guided Strategy. Clinical Trial Design. Revista espanola de cardiologia (English ed.), 2017, Volume: 70, Issue:12 Topics: Acetazolamide; Acute Disease; CA-125 Antigen; Cardio-Renal Syndrome; Chlorthalidone; Creatinine; Diu	2017
Diuretic Strategies in Acute Heart Failure and Renal Dysfunction: Conventional vs Carbohydrate Antigen 125-guided Strategy. Clinical Trial Design. Revista espanola de cardiologia (English ed.), 2017, Volume: 70, Issue:12 Topics: Acetazolamide; Acute Disease; CA-125 Antigen; Cardio-Renal Syndrome; Chlorthalidone; Creatinine; Diu	2017
Risk Factors Influencing Outcomes of Atrial Fibrillation in ALLHAT. Journal of the National Medical Association, 2018, Volume: 110, Issue:4 Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Atrial Flutter; C	2018
Risk Factors Influencing Outcomes of Atrial Fibrillation in ALLHAT. Journal of the National Medical Association, 2018, Volume: 110, Issue:4 Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Atrial Flutter; C	2018
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography	2019
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography	2019
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography	2019
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography	2019
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography	2019
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography	2019
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography	2019
Prevention of Heart Failure in Hypertension-Disentangling the Role of Evolving Left Ventricular Hypertrophy and Blood Pressure Lowering: The ALLHAT Study. Journal of the American Heart Association, 2019, 04-16, Volume: 8, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Causality; Chlorthalidone; Doxazosin; Electrocardiography	2019
Mortality and morbidity during and after Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial: results by sex. Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:5 Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalido	2013
Mortality and morbidity during and after Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial: results by sex. Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:5 Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Chlorthalido	2013
ALLHAT findings revisited in the context of subsequent analyses, other trials, and meta-analyses. Archives of internal medicine, 2009, May-11, Volume: 169, Issue:9 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; C	2009
ALLHAT findings revisited in the context of subsequent analyses, other trials, and meta-analyses. Archives of internal medicine, 2009, May-11, Volume: 169, Issue:9 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; C	2009
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PloS one, 2012, Volume: 7, Issue:3 Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-	2012
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PloS one, 2012, Volume: 7, Issue:3 Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-	2012
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PloS one, 2012, Volume: 7, Issue:3 Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-	2012
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PloS one, 2012, Volume: 7, Issue:3 Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-	2012
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PloS one, 2012, Volume: 7, Issue:3 Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-	2012
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PloS one, 2012, Volume: 7, Issue:3 Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-	2012
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PloS one, 2012, Volume: 7, Issue:3 Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-	2012
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study. PloS one, 2012, Volume: 7, Issue:3 Topics: Aged; Alleles; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Double-	2012
Long-term renal and cardiovascular outcomes in Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) participants by baseline estimated GFR. Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:6 Topics: Amlodipine; Antihypertensive Agents; Canada; Chlorthalidone; Chronic Disease; Coronary Disease; Doub	2012
Long-term renal and cardiovascular outcomes in Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) participants by baseline estimated GFR. Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:6 Topics: Amlodipine; Antihypertensive Agents; Canada; Chlorthalidone; Chronic Disease; Coronary Disease; Doub	2012
Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Circulation, 2006, May-09, Volume: 113, Issue:18 Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihyperte	2006
Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Circulation, 2006, May-09, Volume: 113, Issue:18 Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihyperte	2006
[Clinical evaluation of hygroton K (author's transl)]. Przeglad lekarski, 1981, Volume: 38, Issue:10 Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Diuretics; Female; H	1981
[Clinical evaluation of hygroton K (author's transl)]. Przeglad lekarski, 1981, Volume: 38, Issue:10 Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Diuretics; Female; H	1981
Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research Group. JAMA, 1997, Jul-16, Volume: 278, Issue:3 Topics: Aged; Antihypertensive Agents; Atenolol; Chlorthalidone; Diuretics; Double-Blind Method; Electrocard	1997
Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research Group. JAMA, 1997, Jul-16, Volume: 278, Issue:3 Topics: Aged; Antihypertensive Agents; Atenolol; Chlorthalidone; Diuretics; Double-Blind Method; Electrocard	1997
National Heart, Lung, and Blood Institute halts part of antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT) Circulation, 2000, Mar-28, Volume: 101, Issue:12 Topics: Adrenergic alpha-Antagonists; Anticholesteremic Agents; Chlorthalidone; Diuretics; Doxazosin; Female	2000
National Heart, Lung, and Blood Institute halts part of antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT) Circulation, 2000, Mar-28, Volume: 101, Issue:12 Topics: Adrenergic alpha-Antagonists; Anticholesteremic Agents; Chlorthalidone; Diuretics; Doxazosin; Female	2000
Implications of discontinuation of doxazosin arm of ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Lancet (London, England), 2000, Mar-11, Volume: 355, Issue:9207 Topics: Adverse Drug Reaction Reporting Systems; Anticholesteremic Agents; Antihypertensive Agents; Chlortha	2000
Implications of discontinuation of doxazosin arm of ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Lancet (London, England), 2000, Mar-11, Volume: 355, Issue:9207 Topics: Adverse Drug Reaction Reporting Systems; Anticholesteremic Agents; Antihypertensive Agents; Chlortha	2000
Alprenolol in hypertension. Acta medica Scandinavica. Supplementum, 1974, Volume: 554 Topics: Aged; Alprenolol; Benzothiadiazines; Chlorthalidone; Clinical Trials as Topic; Digitalis; Diuretics;	1974
Alprenolol in hypertension. Acta medica Scandinavica. Supplementum, 1974, Volume: 554 Topics: Aged; Alprenolol; Benzothiadiazines; Chlorthalidone; Clinical Trials as Topic; Digitalis; Diuretics;	1974
[Mefrusid, a new diuretic. A clinical comparison with chlorthalidone with special reference to the water-electrolyte balance]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Jul-01, Volume: 90, Issue:13 Topics: Aged; Chemical Phenomena; Chemistry; Chlorthalidone; Diuretics; Female; Heart Failure; Humans; Male;	1970
[Mefrusid, a new diuretic. A clinical comparison with chlorthalidone with special reference to the water-electrolyte balance]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Jul-01, Volume: 90, Issue:13 Topics: Aged; Chemical Phenomena; Chemistry; Chlorthalidone; Diuretics; Female; Heart Failure; Humans; Male;	1970

Article	Year
Contributions of Systolic and Diastolic Blood Pressures to Cardiovascular Outcomes in the ALLHAT Study. Journal of the American College of Cardiology, 2021, 10-26, Volume: 78, Issue:17 Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Chlorthalid	2021
Contributions of Systolic and Diastolic Blood Pressures to Cardiovascular Outcomes in the ALLHAT Study. Journal of the American College of Cardiology, 2021, 10-26, Volume: 78, Issue:17 Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Chlorthalid	2021
Comparison of chlorthalidone and spironolactone as additional diuretic therapy in patients with acute heart failure and preserved ejection fraction. European heart journal. Acute cardiovascular care, 2022, Jun-07, Volume: 11, Issue:4 Topics: Aged, 80 and over; Chlorthalidone; Diuretics; Female; Heart Failure; Humans; Male; Sodium; Spironola	2022
Comparison of chlorthalidone and spironolactone as additional diuretic therapy in patients with acute heart failure and preserved ejection fraction. European heart journal. Acute cardiovascular care, 2022, Jun-07, Volume: 11, Issue:4 Topics: Aged, 80 and over; Chlorthalidone; Diuretics; Female; Heart Failure; Humans; Male; Sodium; Spironola	2022
CANDI study: chlorthalidone vs acetazolamide in patients with diuretic resistance in acute heart failure. Revista espanola de cardiologia (English ed.), 2023, Volume: 76, Issue:6 Topics: Acetazolamide; Chlorthalidone; Diuretics; Heart Failure; Humans	2023
CANDI study: chlorthalidone vs acetazolamide in patients with diuretic resistance in acute heart failure. Revista espanola de cardiologia (English ed.), 2023, Volume: 76, Issue:6 Topics: Acetazolamide; Chlorthalidone; Diuretics; Heart Failure; Humans	2023
CANDI study: chlorthalidone vs acetazolamide in patients with diuretic resistance in acute heart failure. Revista espanola de cardiologia (English ed.), 2023, Volume: 76, Issue:6 Topics: Acetazolamide; Chlorthalidone; Diuretics; Heart Failure; Humans	2023
CANDI study: chlorthalidone vs acetazolamide in patients with diuretic resistance in acute heart failure. Revista espanola de cardiologia (English ed.), 2023, Volume: 76, Issue:6 Topics: Acetazolamide; Chlorthalidone; Diuretics; Heart Failure; Humans	2023
CANDI study: chlorthalidone vs acetazolamide in patients with diuretic resistance in acute heart failure. Revista espanola de cardiologia (English ed.), 2023, Volume: 76, Issue:6 Topics: Acetazolamide; Chlorthalidone; Diuretics; Heart Failure; Humans	2023
CANDI study: chlorthalidone vs acetazolamide in patients with diuretic resistance in acute heart failure. Revista espanola de cardiologia (English ed.), 2023, Volume: 76, Issue:6 Topics: Acetazolamide; Chlorthalidone; Diuretics; Heart Failure; Humans	2023
CANDI study: chlorthalidone vs acetazolamide in patients with diuretic resistance in acute heart failure. Revista espanola de cardiologia (English ed.), 2023, Volume: 76, Issue:6 Topics: Acetazolamide; Chlorthalidone; Diuretics; Heart Failure; Humans	2023
CANDI study: chlorthalidone vs acetazolamide in patients with diuretic resistance in acute heart failure. Revista espanola de cardiologia (English ed.), 2023, Volume: 76, Issue:6 Topics: Acetazolamide; Chlorthalidone; Diuretics; Heart Failure; Humans	2023
Usefulness of urinary potassium to creatinine ratio to predict diuretic response in patients with acute heart failure and preserved ejection fraction. Clinical cardiology, 2023, Volume: 46, Issue:8 Topics: Aged, 80 and over; Chlorthalidone; Creatinine; Diuretics; Female; Heart Failure; Humans; Male; Potas	2023
Usefulness of urinary potassium to creatinine ratio to predict diuretic response in patients with acute heart failure and preserved ejection fraction. Clinical cardiology, 2023, Volume: 46, Issue:8 Topics: Aged, 80 and over; Chlorthalidone; Creatinine; Diuretics; Female; Heart Failure; Humans; Male; Potas	2023
Not just chlorthalidone: evidence-based, single tablet, diuretic alternatives to hydrochlorothiazide for hypertension. Current hypertension reports, 2015, Volume: 17, Issue:4 Topics: Animals; Blood Pressure; Chlorthalidone; Evidence-Based Practice; Heart Failure; Humans; Hypertensio	2015
Not just chlorthalidone: evidence-based, single tablet, diuretic alternatives to hydrochlorothiazide for hypertension. Current hypertension reports, 2015, Volume: 17, Issue:4 Topics: Animals; Blood Pressure; Chlorthalidone; Evidence-Based Practice; Heart Failure; Humans; Hypertensio	2015
Prevention of heart failure with chlorthalidone in ALLHAT: placing the results into perspective. Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:9 Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Heart Failure; Humans; Hypertension; Sodium Chlo	2009
Prevention of heart failure with chlorthalidone in ALLHAT: placing the results into perspective. Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:9 Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Heart Failure; Humans; Hypertension; Sodium Chlo	2009
Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis. Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:4 Topics: Adult; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Cholesterol; Heart	2011
Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis. Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:4 Topics: Adult; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Cholesterol; Heart	2011
How much effect of different antihypertensive medications on cardiovascular outcomes is attributable to their effects on blood pressure? Statistics in medicine, 2013, Feb-28, Volume: 32, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Biostatistics; Blood Pressure; Cardiovascular Diseases; Chlorth	2013
How much effect of different antihypertensive medications on cardiovascular outcomes is attributable to their effects on blood pressure? Statistics in medicine, 2013, Feb-28, Volume: 32, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Biostatistics; Blood Pressure; Cardiovascular Diseases; Chlorth	2013
[The ALLHAT study: contributions, limitations and prospectives]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2003, Volume: 4, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiov	2003
[The ALLHAT study: contributions, limitations and prospectives]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2003, Volume: 4, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiov	2003
[The new (old) knowledge in primary prevention of stroke. It depends on lowering of blood pressure]. MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1 Topics: Adrenergic alpha-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive	2003
[The new (old) knowledge in primary prevention of stroke. It depends on lowering of blood pressure]. MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1 Topics: Adrenergic alpha-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive	2003
[Diuretic and saluretic activity of Hygroton in emphysematous and silicotic patients with cardiorespiratory insufficiency]. La Medicina del lavoro, 1961, Volume: 52 Topics: Chlorthalidone; Diuretics; Heart Failure; Humans; Pulmonary Emphysema; Silicosis	1961
[Diuretic and saluretic activity of Hygroton in emphysematous and silicotic patients with cardiorespiratory insufficiency]. La Medicina del lavoro, 1961, Volume: 52 Topics: Chlorthalidone; Diuretics; Heart Failure; Humans; Pulmonary Emphysema; Silicosis	1961
[Clinical experiences in the treatment of edematous diseases with Hygroton]. Therapie der Gegenwart, 1961, Volume: 100 Topics: Ascites; Chlorthalidone; Diuretics; Edema; Heart Failure; Humans; Nephrosis	1961
[Clinical experiences in the treatment of edematous diseases with Hygroton]. Therapie der Gegenwart, 1961, Volume: 100 Topics: Ascites; Chlorthalidone; Diuretics; Edema; Heart Failure; Humans; Nephrosis	1961
[Diuretic and saluretic action of an aldosterone antagonist (spirolactone, SC-9420) associated with an iso-indoline derivative (Hygroton) in refractory cardiac edema]. Bollettino della Societa italiana di cardiologia, 1962, Volume: 7 Topics: Aldosterone; Antihypertensive Agents; Chlorthalidone; Diuretics; Edema, Cardiac; Heart Failure; Indo	1962
[Diuretic and saluretic action of an aldosterone antagonist (spirolactone, SC-9420) associated with an iso-indoline derivative (Hygroton) in refractory cardiac edema]. Bollettino della Societa italiana di cardiologia, 1962, Volume: 7 Topics: Aldosterone; Antihypertensive Agents; Chlorthalidone; Diuretics; Edema, Cardiac; Heart Failure; Indo	1962
[Experiences with chlorthalidone (Hygroton)]. Geneeskundige gids, 1963, Apr-18, Volume: 41 Topics: Ascites; Chlorthalidone; Edema; Heart Failure; Liver Cirrhosis	1963
[Experiences with chlorthalidone (Hygroton)]. Geneeskundige gids, 1963, Apr-18, Volume: 41 Topics: Ascites; Chlorthalidone; Edema; Heart Failure; Liver Cirrhosis	1963
Comparison of meralluride with a new oral diuretic. The Illinois medical journal, 1963, Volume: 124 Topics: Chlorthalidone; Diuretics; Heart Failure; Hypertension; Liver Cirrhosis; Organomercury Compounds; Or	1963
Comparison of meralluride with a new oral diuretic. The Illinois medical journal, 1963, Volume: 124 Topics: Chlorthalidone; Diuretics; Heart Failure; Hypertension; Liver Cirrhosis; Organomercury Compounds; Or	1963
Chlorthalidone, a new oral diuretic: preliminary report. Applied therapeutics, 1961, Volume: 3 Topics: Chlorthalidone; Diuretics; Heart Failure; Liver Cirrhosis	1961
Chlorthalidone, a new oral diuretic: preliminary report. Applied therapeutics, 1961, Volume: 3 Topics: Chlorthalidone; Diuretics; Heart Failure; Liver Cirrhosis	1961
TREATMENT OF EDEMA BY THE COMBINED ADMINISTRATION OF CHEMICALLY DIFFERENT DIURETIC AGENTS. The American journal of cardiology, 1963, Volume: 12 Topics: Ascites; Chlorthalidone; Diuretics; Edema; Heart Failure; Humans; Hydrochlorothiazide; Organomercury	1963
TREATMENT OF EDEMA BY THE COMBINED ADMINISTRATION OF CHEMICALLY DIFFERENT DIURETIC AGENTS. The American journal of cardiology, 1963, Volume: 12 Topics: Ascites; Chlorthalidone; Diuretics; Edema; Heart Failure; Humans; Hydrochlorothiazide; Organomercury	1963
[ON ION TRANSPORT BEFORE AND AFTER TREATMENT OF CONGESTIVE HEART FAILURE]. Turk Tip Cemiyeti mecmuasi, 1963, Volume: 29 Topics: Chlorthalidone; Coronary Disease; Digitalis Glycosides; Diuretics; Electrolytes; Heart Failure; Huma	1963
[ON ION TRANSPORT BEFORE AND AFTER TREATMENT OF CONGESTIVE HEART FAILURE]. Turk Tip Cemiyeti mecmuasi, 1963, Volume: 29 Topics: Chlorthalidone; Coronary Disease; Digitalis Glycosides; Diuretics; Electrolytes; Heart Failure; Huma	1963
[ON THE DOSAGE OF SALURETICS]. Wiener medizinische Wochenschrift (1946), 1963, Dec-07, Volume: 113 Topics: Alkalosis; Chlorthalidone; Diuretics; Edema; Female; Heart Failure; Liver Cirrhosis; Pregnancy; Preg	1963
[ON THE DOSAGE OF SALURETICS]. Wiener medizinische Wochenschrift (1946), 1963, Dec-07, Volume: 113 Topics: Alkalosis; Chlorthalidone; Diuretics; Edema; Female; Heart Failure; Liver Cirrhosis; Pregnancy; Preg	1963
TREATMENT OF ARTERIAL HYPERTENSIVE DISEASE WITH DIURETICS. III. CHLORTHALIDONE ALONE AND IN COMBINATION WITH SPIRONOLACTONE. The American journal of the medical sciences, 1964, Volume: 247 Topics: Bendroflumethiazide; Cardiomegaly; Chlorides; Chlorthalidone; Coronary Disease; Creatine; Creatinine	1964
TREATMENT OF ARTERIAL HYPERTENSIVE DISEASE WITH DIURETICS. III. CHLORTHALIDONE ALONE AND IN COMBINATION WITH SPIRONOLACTONE. The American journal of the medical sciences, 1964, Volume: 247 Topics: Bendroflumethiazide; Cardiomegaly; Chlorides; Chlorthalidone; Coronary Disease; Creatine; Creatinine	1964
NEUTROPENIA ASSOCIATED WITH CHLORTHALIDONE THERAPY. The Medical journal of Australia, 1964, Mar-07, Volume: 1 Topics: Agranulocytosis; Chlorthalidone; Geriatrics; Heart Failure; Neutropenia; Toxicology	1964
NEUTROPENIA ASSOCIATED WITH CHLORTHALIDONE THERAPY. The Medical journal of Australia, 1964, Mar-07, Volume: 1 Topics: Agranulocytosis; Chlorthalidone; Geriatrics; Heart Failure; Neutropenia; Toxicology	1964
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS]. Vie medicale (Paris, France : 1920), 1964, Volume: 45 Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics;	1964
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS]. Vie medicale (Paris, France : 1920), 1964, Volume: 45 Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics;	1964
TRIAMTERENE COMBINED WITH OTHER DIURETICS IN CONGESTIVE HEART FAILURE. Acta cardiologica, 1964, Volume: 19 Topics: Chlorthalidone; Diuretics; Geriatrics; Heart Failure; Pterins; Spironolactone; Toxicology; Triamtere	1964
TRIAMTERENE COMBINED WITH OTHER DIURETICS IN CONGESTIVE HEART FAILURE. Acta cardiologica, 1964, Volume: 19 Topics: Chlorthalidone; Diuretics; Geriatrics; Heart Failure; Pterins; Spironolactone; Toxicology; Triamtere	1964
CARDIAC AND METABOLIC DISEASE, AND INFECTIONS IN THE OBSTETRIC PATIENT. Clinical obstetrics and gynecology, 1964, Volume: 13 Topics: Acetazolamide; Acid-Base Equilibrium; Blood Circulation; Chlorothiazide; Chlorthalidone; Diet, Sodiu	1964
CARDIAC AND METABOLIC DISEASE, AND INFECTIONS IN THE OBSTETRIC PATIENT. Clinical obstetrics and gynecology, 1964, Volume: 13 Topics: Acetazolamide; Acid-Base Equilibrium; Blood Circulation; Chlorothiazide; Chlorthalidone; Diet, Sodiu	1964
[CLINICAL STUDY OF THE INTERACTION OF DIGITALIS AND A DIURETIC ON POTASSIUM AND SODIUM METABOLISM]. Acta clinica Belgica, 1964, Volume: 19 Topics: Chlorthalidone; Digitalis; Digitalis Glycosides; Diuretics; Heart Failure; Humans; Metabolism; Potas	1964
[CLINICAL STUDY OF THE INTERACTION OF DIGITALIS AND A DIURETIC ON POTASSIUM AND SODIUM METABOLISM]. Acta clinica Belgica, 1964, Volume: 19 Topics: Chlorthalidone; Digitalis; Digitalis Glycosides; Diuretics; Heart Failure; Humans; Metabolism; Potas	1964
[URATIC ARTHRITIS AS A COMPLICATION OF DIURETIC THERAPY]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1964, Jul-15, Volume: 84 Topics: Arthritis; Chlorothiazide; Chlorthalidone; Diuretics; Gout; Heart Failure; Hypertension; Rheumatic H	1964
[URATIC ARTHRITIS AS A COMPLICATION OF DIURETIC THERAPY]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1964, Jul-15, Volume: 84 Topics: Arthritis; Chlorothiazide; Chlorthalidone; Diuretics; Gout; Heart Failure; Hypertension; Rheumatic H	1964
A NEW EFFECTIVE DIURETIC--LASIX. British medical journal, 1964, Oct-10, Volume: 2, Issue:5414 Topics: Chlorthalidone; Diuretics; Drug Therapy; Furosemide; Heart Failure; Hydrochlorothiazide; Hypokalemia	1964
A NEW EFFECTIVE DIURETIC--LASIX. British medical journal, 1964, Oct-10, Volume: 2, Issue:5414 Topics: Chlorthalidone; Diuretics; Drug Therapy; Furosemide; Heart Failure; Hydrochlorothiazide; Hypokalemia	1964
A CLINICAL TRIAL OF FRUSEMIDE. Lancet (London, England), 1964, Nov-21, Volume: 2, Issue:7369 Topics: Biomedical Research; Blood Chemical Analysis; Chlorides; Chlorthalidone; Diuretics; Fluids and Secre	1964
A CLINICAL TRIAL OF FRUSEMIDE. Lancet (London, England), 1964, Nov-21, Volume: 2, Issue:7369 Topics: Biomedical Research; Blood Chemical Analysis; Chlorides; Chlorthalidone; Diuretics; Fluids and Secre	1964
CLINICAL AND BIOCHEMICAL STUDIES ON A NEW DIURETIC: CHLORTHALIDONE. The Journal of the Association of Physicians of India, 1964, Volume: 12 Topics: Adolescent; Chlorthalidone; Diuretics; Drug Therapy; Edema; Geriatrics; Heart Failure; Kidney Diseas	1964
CLINICAL AND BIOCHEMICAL STUDIES ON A NEW DIURETIC: CHLORTHALIDONE. The Journal of the Association of Physicians of India, 1964, Volume: 12 Topics: Adolescent; Chlorthalidone; Diuretics; Drug Therapy; Edema; Geriatrics; Heart Failure; Kidney Diseas	1964
CLINICAL EVALUATION OF POLYTHIAZIDE IN HYPERTENSION AND CONGESTIVE HEART FAILURE: A COMPARATIVE DOUBLE-BLIND STUDY. The American journal of the medical sciences, 1965, Volume: 249 Topics: Biomedical Research; Blood Chemical Analysis; Blood Pressure; Body Weight; Chlorthalidone; Diuresis;	1965
CLINICAL EVALUATION OF POLYTHIAZIDE IN HYPERTENSION AND CONGESTIVE HEART FAILURE: A COMPARATIVE DOUBLE-BLIND STUDY. The American journal of the medical sciences, 1965, Volume: 249 Topics: Biomedical Research; Blood Chemical Analysis; Blood Pressure; Body Weight; Chlorthalidone; Diuresis;	1965
FUROSEMIDE (LASIX) AS A DIURETIC. Acta medica Scandinavica, 1965, Volume: 177 Topics: Chlorothiazide; Chlorthalidone; Diuretics; Drug Therapy; Furosemide; Heart Failure; Hydrochlorothiaz	1965
FUROSEMIDE (LASIX) AS A DIURETIC. Acta medica Scandinavica, 1965, Volume: 177 Topics: Chlorothiazide; Chlorthalidone; Diuretics; Drug Therapy; Furosemide; Heart Failure; Hydrochlorothiaz	1965
Preventing vascular events due to elevated blood pressure. Circulation, 2006, May-09, Volume: 113, Issue:18 Topics: Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Comorbidity; Doxazosin; Drug Thera	2006
Preventing vascular events due to elevated blood pressure. Circulation, 2006, May-09, Volume: 113, Issue:18 Topics: Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Comorbidity; Doxazosin; Drug Thera	2006
Hypertensive vascular disease. The long term effect of rapid repeated reductions of arterial pressure with diazoxide. The American journal of cardiology, 1967, Volume: 19, Issue:3 Topics: Adult; Chlorthalidone; Diazoxide; Female; Heart Failure; Humans; Hydralazine; Hypertension; Injectio	1967
Hypertensive vascular disease. The long term effect of rapid repeated reductions of arterial pressure with diazoxide. The American journal of cardiology, 1967, Volume: 19, Issue:3 Topics: Adult; Chlorthalidone; Diazoxide; Female; Heart Failure; Humans; Hydralazine; Hypertension; Injectio	1967
The practicing physician and control of hypertension. Comprehensive therapy, 1980, Volume: 6, Issue:3 Topics: Adult; Aged; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Female; Heart Failure; Hum	1980
The practicing physician and control of hypertension. Comprehensive therapy, 1980, Volume: 6, Issue:3 Topics: Adult; Aged; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Female; Heart Failure; Hum	1980
[Acute tubular necrosis caused by combination of diuretics in the treatment of several heart failure. A call to attention]. Revista clinica espanola, 1997, Volume: 197, Issue:8 Topics: Aged; Chlorthalidone; Diuretics; Furosemide; Heart Failure; Humans; Kidney Tubular Necrosis, Acute;	1997
[Acute tubular necrosis caused by combination of diuretics in the treatment of several heart failure. A call to attention]. Revista clinica espanola, 1997, Volume: 197, Issue:8 Topics: Aged; Chlorthalidone; Diuretics; Furosemide; Heart Failure; Humans; Kidney Tubular Necrosis, Acute;	1997
A cautionary tale. Australian family physician, 1997, Volume: 26, Issue:10 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Calcium Channel Blockers; Ch	1997
A cautionary tale. Australian family physician, 1997, Volume: 26, Issue:10 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Calcium Channel Blockers; Ch	1997
Alpha-blockers and congestive heart failure: early termination of an arm of the ALLHAT trial. Cleveland Clinic journal of medicine, 2000, Volume: 67, Issue:6 Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Chlorthalidone; Doxazosin; Female; Heart Fail	2000
Alpha-blockers and congestive heart failure: early termination of an arm of the ALLHAT trial. Cleveland Clinic journal of medicine, 2000, Volume: 67, Issue:6 Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Chlorthalidone; Doxazosin; Female; Heart Fail	2000
First-line antihypertensive therapy. Lancet (London, England), 2000, Aug-05, Volume: 356, Issue:9228 Topics: Antihypertensive Agents; Chlorthalidone; Doxazosin; Heart Failure; Humans; Myocardium; Randomized Co	2000
First-line antihypertensive therapy. Lancet (London, England), 2000, Aug-05, Volume: 356, Issue:9228 Topics: Antihypertensive Agents; Chlorthalidone; Doxazosin; Heart Failure; Humans; Myocardium; Randomized Co	2000
[Alpha-blockers in therapy of arterial hypertension. No longer the drug of first choice]. MMW Fortschritte der Medizin, 2001, May-31, Volume: 143, Issue:22 Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Cause of Death; Chlorthalidone; Doxazos	2001
[Alpha-blockers in therapy of arterial hypertension. No longer the drug of first choice]. MMW Fortschritte der Medizin, 2001, May-31, Volume: 143, Issue:22 Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Cause of Death; Chlorthalidone; Doxazos	2001
[Serum and total body potassium during treatment with chlortalidone and hydrochlorothiazide. Influence of triamterene (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1977, Dec-16, Volume: 102, Issue:50 Topics: Adult; Aged; Chlorthalidone; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrochloroth	1977
[Serum and total body potassium during treatment with chlortalidone and hydrochlorothiazide. Influence of triamterene (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1977, Dec-16, Volume: 102, Issue:50 Topics: Adult; Aged; Chlorthalidone; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrochloroth	1977
Carotid sinus hypersensitivity with alpha methyldopa. Annals of internal medicine, 1978, Volume: 88, Issue:2 Topics: Aged; Carotid Sinus; Chlorthalidone; Female; Heart Failure; Humans; Hypersensitivity; Methyldopa; Re	1978
Carotid sinus hypersensitivity with alpha methyldopa. Annals of internal medicine, 1978, Volume: 88, Issue:2 Topics: Aged; Carotid Sinus; Chlorthalidone; Female; Heart Failure; Humans; Hypersensitivity; Methyldopa; Re	1978
Systemic hypertension complicating tetralogy of Fallot: effects of antihypertensive therapy. The American journal of cardiology, 1978, Volume: 42, Issue:2 Topics: Adult; Angiocardiography; Cardiac Catheterization; Chlorthalidone; Female; Heart Failure; Heart Sept	1978
Systemic hypertension complicating tetralogy of Fallot: effects of antihypertensive therapy. The American journal of cardiology, 1978, Volume: 42, Issue:2 Topics: Adult; Angiocardiography; Cardiac Catheterization; Chlorthalidone; Female; Heart Failure; Heart Sept	1978
[On the pathogenesis and treatment of cardiac insufficiency]. Recenti progressi in medicina, 1978, Volume: 65, Issue:2 Topics: Chlorthalidone; Digoxin; Furosemide; Heart Failure; Humans; Water-Electrolyte Balance	1978
[On the pathogenesis and treatment of cardiac insufficiency]. Recenti progressi in medicina, 1978, Volume: 65, Issue:2 Topics: Chlorthalidone; Digoxin; Furosemide; Heart Failure; Humans; Water-Electrolyte Balance	1978
[Combined treatment with furosemide, aldactone and hygroton in chronic right-ventricular circulatory failure]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1977, Aug-01, Volume: 30, Issue:15 Topics: Chlorthalidone; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Heart Ventricles; Huma	1977
[Combined treatment with furosemide, aldactone and hygroton in chronic right-ventricular circulatory failure]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1977, Aug-01, Volume: 30, Issue:15 Topics: Chlorthalidone; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Heart Ventricles; Huma	1977
[Use of saluretic preparation hygrotone for the treatment of patients with chronic circulatory insufficiency]. Kardiologiia, 1974, Volume: 14, Issue:7 Topics: Adult; Aged; Ammonia; Chlorthalidone; Chronic Disease; Diuresis; Female; Glomerular Filtration Rate;	1974
[Use of saluretic preparation hygrotone for the treatment of patients with chronic circulatory insufficiency]. Kardiologiia, 1974, Volume: 14, Issue:7 Topics: Adult; Aged; Ammonia; Chlorthalidone; Chronic Disease; Diuresis; Female; Glomerular Filtration Rate;	1974
Importance of the adrenergic nervous system in the support of cardiac function in patients with primary arterial hypertension. Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1 Topics: Body Weight; Cardiac Output; Chlorthalidone; Digitalis Glycosides; Glomerular Filtration Rate; Guane	1973
Importance of the adrenergic nervous system in the support of cardiac function in patients with primary arterial hypertension. Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1 Topics: Body Weight; Cardiac Output; Chlorthalidone; Digitalis Glycosides; Glomerular Filtration Rate; Guane	1973
[Cardiac insufficiency appearing in essential arterial hypertension]. Bulletin de l'Academie royale de medecine de Belgique, 1972, Volume: 12, Issue:2 Topics: Chlorthalidone; Guanethidine; Heart Failure; Humans; Hypertension; Reserpine	1972
[Cardiac insufficiency appearing in essential arterial hypertension]. Bulletin de l'Academie royale de medecine de Belgique, 1972, Volume: 12, Issue:2 Topics: Chlorthalidone; Guanethidine; Heart Failure; Humans; Hypertension; Reserpine	1972
Management of refractory heart failure. Progress in cardiovascular diseases, 1970, Volume: 12, Issue:6 Topics: Arrhythmias, Cardiac; Benzothiadiazines; Chlorthalidone; Digitalis Glycosides; Diuretics; Heart Fail	1970
Management of refractory heart failure. Progress in cardiovascular diseases, 1970, Volume: 12, Issue:6 Topics: Arrhythmias, Cardiac; Benzothiadiazines; Chlorthalidone; Digitalis Glycosides; Diuretics; Heart Fail	1970
[Some aspects of renal metabolism of citric acid]. Minerva medica, 1970, Sep-01, Volume: 61, Issue:70 Topics: Adult; Age Factors; Aged; Chlorthalidone; Citrates; Heart Failure; Humans; Hydrochlorothiazide; Hype	1970
[Some aspects of renal metabolism of citric acid]. Minerva medica, 1970, Sep-01, Volume: 61, Issue:70 Topics: Adult; Age Factors; Aged; Chlorthalidone; Citrates; Heart Failure; Humans; Hydrochlorothiazide; Hype	1970
Failure of repeated diazoxide injections to modify the course of severe hypertension. American heart journal, 1971, Volume: 81, Issue:5 Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diazoxide; Diuretics; Guanethidine; Heart F	1971
Failure of repeated diazoxide injections to modify the course of severe hypertension. American heart journal, 1971, Volume: 81, Issue:5 Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diazoxide; Diuretics; Guanethidine; Heart F	1971
[Furosemide in the treatment of cardiac insufficiency]. Medicina interna, 1967, Volume: 19, Issue:11 Topics: Adult; Aged; Chlorothiazide; Chlorthalidone; Diuresis; Electrolytes; Female; Furosemide; Heart Failu	1967
[Furosemide in the treatment of cardiac insufficiency]. Medicina interna, 1967, Volume: 19, Issue:11 Topics: Adult; Aged; Chlorothiazide; Chlorthalidone; Diuresis; Electrolytes; Female; Furosemide; Heart Failu	1967
[Diuretic therapy with chlorthalidone in congestive heart failure caused by chronic cor pulmonale]. La Clinica terapeutica, 1967, Jul-15, Volume: 42, Issue:1 Topics: Adult; Aged; Chlorthalidone; Chronic Disease; Diuresis; Electrolytes; Heart Failure; Humans; Male; M	1967
[Diuretic therapy with chlorthalidone in congestive heart failure caused by chronic cor pulmonale]. La Clinica terapeutica, 1967, Jul-15, Volume: 42, Issue:1 Topics: Adult; Aged; Chlorthalidone; Chronic Disease; Diuresis; Electrolytes; Heart Failure; Humans; Male; M	1967

chlorthalidone and Heart Failure

Research Excerpts

Research

Studies (71)

Authors

Clinical Trials (4)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Itoga, NK	1
Tawfik, DS	1
Montez-Rath, ME	1
Chang, TI	1
Llàcer, P	3
Núñez, J	3
García, M	2
Ruiz, R	2
López, G	2
Fabregate, M	2
Fernández, C	2
Croset, F	2
Del Hoyo, B	2
Gomis, A	2
Manzano, L	2
Vela Martín, P	2
Matutano Muñoz, A	2
Sánchez Ortiz, D	2
Domínguez, F	2
Royuela, A	2
Cobo Marcos, M	2
Campos, J	1
García-Blas, S	1
Bonanad, C	1
Ventura, S	1
Núñez, JM	1
Sánchez, R	1
Chamorro, C	1
Fácila, L	1
de la Espriella, R	1
Vaquer, JM	1
Cordero, A	1
Roqué, M	1
Ortiz, V	1
Racugno, P	1
Bodí, V	1
Valero, E	1
Santas, E	1
Moreno, MDC	1
Miñana, G	1
Carratalá, A	1
Bondanza, L	1
Payá, A	1
Cardells, I	1
Heredia, R	1
Pellicer, M	1
Valls, G	1
Palau, P	1
Bosch, MJ	1
Raso, R	1
Sánchez, A	1
Bertomeu-González, V	1
Bertomeu-Martínez, V	1
Montagud-Balaguer, V	1
Albiach-Montañana, C	1
Pendás-Meneau, J	1
Marcaida, G	1
Cervantes-García, S	1
San Antonio, R	1
de Mingo, E	1
Chorro, FJ	1
Sanchis, J	1
Haywood, LJ	4
Davis, BR	10
Piller, LB	3
Simpson, LM	1
Ghosh, A	1
Einhorn, PT	3
Ford, CE	6
Probstfield, JL	3
Soliman, EZ	1
Wright, JT	5
Johnson, K	1
Oparil, S	4
Tereshchenko, LG	1
Cushman, WC	3
Furberg, CD	2
Habib, GB	1
Margolis, K	1
Whelton, PK	4
Thomopoulos, C	1
Parati, G	1
Zanchetti, A	1
Roush, GC	1
Ernst, ME	1
Kostis, JB	2
Kaur, R	1
Sica, DA	1
Pressel, SL	2
Cutler, JA	4
Rahman, M	3
Margolis, KL	1
Black, HR	2
Alderman, MH	2
Massie, BM	1
Dorsch, MP	1
Gillespie, BW	1
Erickson, SR	1
Bleske, BE	1
Weder, AB	1
Zhang, X	1
Lynch, AI	1
Boerwinkle, E	1
Eckfeldt, JH	1
Leiendecker-Foster, C	1
Arnett, DK	1
Barzilay, JI	1
Brown, CD	1
Colon, PJ	1
Fine, LJ	1
Grimm, RH	2
Gupta, AK	1
Baimbridge, C	1
Henriquez, MA	1
Ilamaythi, E	1
Preston, R	1
Proschan, M	2
Graumlich, JF	1
Pavlik, V	1
Gordon, D	1
Franklin, SS	1
Blumenthal, SS	1
Castaldo, RS	1
Preston, RA	1
Mancia, G	1
Düsing, R	1
SARTORELLI, E	2
GRISLER, R	1
GRIECO, A	1
ZEDDA, S	1
GLASER, E	1
RUST, S	1
STRATA, A	1
PREIS, H	1
PISO, HJ	1
GOODMAN, RM	1
COMINGS, DE	1
STEIGMANN, F	1
VOLPE, R	1
MAUTNER, LS	1
SELLER, RH	1
FUCHS, M	1
SWARTZ, C	1
BREST, AN	2
MOYER, JH	1
THAYER, JM	1
HEALY, FA	1
OZDOGAN, E	1
WOLKERSTORFER, H	1
JOHNSTON, LC	1
GRIEBLE, HG	1
SCHOENBERGER, JA	1
FULLER, JB	1
TURNER, NA	1
WOODLIFF, HJ	1
BAGROS, P	1
JOOSSENS, JV	1
VERWILGEN, R	1
VERBERCKMOES, R	1
PLATT, MA	1
STAQUET, M	1
DEMANET, JC	1
MERCENIER, J	1
LIUM, O	1
TVETER, KJ	1
STOKES, W	1
VEREL, D	1
STENTIFORD, NH	1
RAHMAN, F	1
SAYNOR, R	1
RAO, CR	1
SAMSON, WE	1
PELTOLA, P	1
Furberg, C	1
Dunn, K	1
Franklin, S	1
Goff, D	1
Leenen, F	1
Mohiuddin, S	1
Papademetriou, V	1
Ellsworth, A	1
Golden, J	1
Colon, P	1
Crow, R	1
Yusuf, S	1
Taniguchi, I	1
Kawai, M	1
Finnerty, FA	2
Davidov, M	1
Kakaviatos, N	1
Rylski, M	1
Rawczyńska-Englert, I	1
Hoffman, M	1
Borhani, NO	1
Cutler, J	1
Berge, KG	1
Cohen, JD	1
Lacy, CR	1
Perry, HM	1
Blaufox, MD	1
Wassertheil-Smoller, S	1
Schron, E	1
Berkson, DM	1
Curb, JD	1
Smith, WM	1
McDonald, R	1
Applegate, WB	1
de Luis, DA	1
Liaño, F	1
Pascual, J	1
Ortuño, J	1
Tallis, GA	1
Phillips, PJ	1
Popplewell, PY	1
SoRelle, R	1
Messerli, FH	1
Vidt, DG	1
Osnes, JB	1
Aass, H	1
Andersen, GO	1
Skomedal, T	1
Faulhaber, HD	1
Schäfer, GE	1
Werner, E	1
Kober, G	1
Kaltenbach, M	1
Bauernfeind, R	1
Hall, C	1
Denes, P	1
Rosen, KM	1
Benge, W	1
White, CW	1
Majorano, G	1
Florkiewicz, H	1
Rymar, B	1
Rumiński, W	1
Staśkiewicz, J	1
Sidorenko, BA	1
Kharchenko, VI	1
Tol'stykh, AN	1
Guazzi, M	1
Polese, A	1
Fiorentini, C	1
Magrini, F	1
Johnsson, G	1
Leiter, L	1
Bartorelli, C	1
Gisholt, K	1
Berg, KJ	1
Gastaldi, L	1
Buccianti, G	1
Rizzato, G	1
Marazzini, L	1
Bucur, V	1
Bunghez, G	1
Tomasini, M	1