Page last updated: 2024-10-25

chlorthalidone and Gout

chlorthalidone has been researched along with Gout in 12 studies

Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.

Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.

Research Excerpts

ExcerptRelevanceReference
"This study assessed the risk of new-onset gout following prescribing of hydrochlorothiazide (HCTZ) compared with chlorthalidone (CTD)."7.80Comparison of new-onset gout in adults prescribed chlorthalidone vs. hydrochlorothiazide for hypertension. ( Nair, KV; Saseen, JJ; Wilson, L, 2014)
"5 mg chlorthalidone on uric acid and electrolyte metabolism was investigated in 22 hypertensive patients with gout in a randomized trial."5.06[Uricosuric action of a new beta receptor blocker-diuretic drug combination]. ( Brandstetter, G; Eslaminejad, S; Hoffmann, H; Maderbacher, H, 1986)
"Amlodipine lowered long-term gout risk compared with lisinopril or chlorthalidone."3.96The effects of antihypertensive class on gout in older adults: secondary analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. ( Beach, JL; Davis, BR; Ishak, A; Juraschek, SP; Mukamal, KJ; Shmerling, RH; Simpson, LM, 2020)
"This study assessed the risk of new-onset gout following prescribing of hydrochlorothiazide (HCTZ) compared with chlorthalidone (CTD)."3.80Comparison of new-onset gout in adults prescribed chlorthalidone vs. hydrochlorothiazide for hypertension. ( Nair, KV; Saseen, JJ; Wilson, L, 2014)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Juraschek, SP1
Simpson, LM1
Davis, BR1
Shmerling, RH1
Beach, JL1
Ishak, A1
Mukamal, KJ1
Wilson, L1
Nair, KV1
Saseen, JJ1
SFIKAKIS, PP1
AVRAMIDIS, AB1
DENKO, CW1
REUTTER, F1
SCHAUB, F1
LIUM, O1
TVETER, KJ1
Bufalari, A1
Meloni, G1
Brandstetter, G1
Hoffmann, H1
Maderbacher, H1
Eslaminejad, S1
Ravera, M1
Spaziante, B1
Thomson, AE1
Ott, H1
Zahnd, G1
Chegoriansky, J1
Piterbarg, R1
Catoggio, PM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000542]Phase 30 participants Interventional1993-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for chlorthalidone and Gout

ArticleYear
[Uricosuric action of a new beta receptor blocker-diuretic drug combination].
    Acta medica Austriaca, 1986, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Celiprolol; Chlorthalidone; Clinical Trials as Topic; Diur

1986

Other Studies

11 other studies available for chlorthalidone and Gout

ArticleYear
The effects of antihypertensive class on gout in older adults: secondary analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
    Journal of hypertension, 2020, Volume: 38, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Female; Gout; H

2020
Comparison of new-onset gout in adults prescribed chlorthalidone vs. hydrochlorothiazide for hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:12

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Cohort Studies; Diuretics; Fem

2014
Hygroton induced gout with a review on sulfonamide diuretics precipitated gouty arthritis.
    Zeitschrift fur Rheumaforschung, 1963, Volume: 22

    Topics: Arthritis, Gouty; Chlorthalidone; Diuretics; Gout; Humans; Sulfanilamide; Sulfanilamides; Sulfonamid

1963
TREATMENT OF THE PATIENT WITH GOUT.
    The Ohio State medical journal, 1963, Volume: 59

    Topics: Chlorthalidone; Colchicine; Diagnosis; Gout; Humans; Oxyphenbutazone; Phenylbutazone; Probenecid; Py

1963
[URIC ACID METABOLISM AND SALIDIURETICS].
    Deutsche medizinische Wochenschrift (1946), 1964, Jun-05, Volume: 89

    Topics: Aged; Chlorothiazide; Chlorthalidone; Diagnosis; Gout; Humans; Hydrochlorothiazide; Metabolism; Toxi

1964
[URATIC ARTHRITIS AS A COMPLICATION OF DIURETIC THERAPY].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1964, Jul-15, Volume: 84

    Topics: Arthritis; Chlorothiazide; Chlorthalidone; Diuretics; Gout; Heart Failure; Hypertension; Rheumatic H

1964
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
    Minerva medica, 1967, Nov-07, Volume: 58, Issue:89

    Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Femal

1967
[Hyperuricemia due to diuretics].
    Minerva medica, 1973, Jan-20, Volume: 64, Issue:4

    Topics: Acetazolamide; Aged; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Gout; H

1973
Chlorthalidone in the long term therapy of patients with hypertension.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 3, Issue:1

    Topics: Adult; Aged; Blood Chemical Analysis; Blood Glucose; Blood Pressure; Carbohydrate Metabolism, Inborn

1970
[Gout and diabetes induced by a salidiuretic treatment].
    Schweizerische medizinische Wochenschrift, 1967, May-20, Volume: 97, Issue:20

    Topics: Aged; Chlorthalidone; Diabetes Mellitus; Diuretics; Female; Gout; Humans; Hyperglycemia; Uremia

1967
[Action of a uricemic depressor (allopurinol) co-administered with a diuretic (chlorthalidon) to gout patients].
    Prensa medica argentina, 1967, Apr-28, Volume: 54, Issue:9

    Topics: Adult; Allopurinol; Chlorthalidone; Gout; Humans; Male; Middle Aged

1967