chlorthalidone has been researched along with Electrolytes in 30 studies
Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " From evidence regarding potency, cardiovascular events, and electrolytes, we hypothesized a priori that 'CHIP' diuretics [CHlorthalidone, Indapamide and Potassium-sparing Diuretic/hydrochlorothiazide (PSD/HCTZ)] would rival RASIs for reducing LVM." | 8.98 | Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis. ( Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S, 2018) |
| "In the majority of hypertensive patients, treatment with 50 mg/d of hydrochlorothiazide does not cause marked hypokalemia or ventricular arrhythmias." | 5.07 | Diuretics, serum and intracellular electrolyte levels, and ventricular arrhythmias in hypertensive men. ( Black, DM; Cheitlin, MD; Fine, R; Hearst, N; Hulley, SB; Sebastian, A; Seeley, DG; Siegel, D, 1992) |
| " To investigate this, 75 out-patients with essential hypertension were treated with chlorthalidone 12." | 5.06 | Plasma renin activity does not predict the antihypertensive efficacy of chlorthalidone. ( Bartolomei, G; Cagianelli, MA; Cinotti, G; Innocenti, P; Loni, C; Papi, L; Pedrinelli, R; Saba, G; Saba, P; Salvetti, A, 1987) |
| " From evidence regarding potency, cardiovascular events, and electrolytes, we hypothesized a priori that 'CHIP' diuretics [CHlorthalidone, Indapamide and Potassium-sparing Diuretic/hydrochlorothiazide (PSD/HCTZ)] would rival RASIs for reducing LVM." | 4.98 | Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis. ( Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S, 2018) |
| "In 79 patients with essential hypertension, treatment with propranolol hydrochloride and chlorthalidone together produced significantly greater falls in both systolic and diastolic blood pressures than were obtained with either drug alone." | 3.65 | Renin reactivity as a determinant of responsiveness to antihypertensive treatment. ( Case, DB; Drayer, JI; Laragh, JH; Lopez-Ovejero, JA; Weber, MA, 1977) |
| "5 mg/day of metolazone or 25 mg/day of chlorthalidone are effective antihypertensive agents but that blood pressure lowering may be inconsistent at these dosage levels." | 2.66 | Low-dose diuretic therapy for hypertension. ( Moser, M, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (90.00) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roush, GC | 1 |
| Abdelfattah, R | 1 |
| Song, S | 1 |
| Kostis, JB | 1 |
| Ernst, ME | 1 |
| Sica, DA | 1 |
| GESSLER, U | 3 |
| NEUHAUS, M | 1 |
| FRANK, H | 1 |
| DENTLER, H | 1 |
| COMOLI, G | 1 |
| GHIRINGHELLI, L | 1 |
| MADULI, S | 1 |
| OZDOGAN, E | 1 |
| BERGSTROEM, J | 1 |
| GILLENWATER, JY | 1 |
| WOLF, K | 1 |
| KELLER, HM | 1 |
| Falch, DK | 1 |
| Schreiner, AM | 1 |
| Schiffl, H | 1 |
| Weidmann, P | 1 |
| Meier, A | 1 |
| Ziegler, WH | 1 |
| Siegel, D | 2 |
| Saliba, P | 1 |
| Haffner, S | 1 |
| Leemhuis, MP | 1 |
| van Damme, KJ | 1 |
| Struyvenberg, A | 1 |
| Gudbrandsson, T | 1 |
| Hansson, L | 1 |
| Dzúrik, R | 1 |
| Danĕková, H | 1 |
| Fedelesová, V | 1 |
| Gergel, J | 1 |
| Weber, MA | 1 |
| Lopez-Ovejero, JA | 1 |
| Drayer, JI | 1 |
| Case, DB | 1 |
| Laragh, JH | 1 |
| Hulley, SB | 1 |
| Black, DM | 1 |
| Cheitlin, MD | 1 |
| Sebastian, A | 1 |
| Seeley, DG | 1 |
| Hearst, N | 1 |
| Fine, R | 1 |
| Salvetti, A | 1 |
| Pedrinelli, R | 1 |
| Bartolomei, G | 1 |
| Cagianelli, MA | 1 |
| Cinotti, G | 1 |
| Innocenti, P | 1 |
| Loni, C | 1 |
| Saba, G | 1 |
| Saba, P | 1 |
| Papi, L | 1 |
| Moser, M | 1 |
| Schück, O | 1 |
| Nádvorníková, H | 1 |
| Heller, J | 1 |
| Tata, PS | 1 |
| Reimold, EW | 1 |
| Bengtsson, C | 1 |
| Lund-Johansen, P | 1 |
| Andersen, JB | 1 |
| Bucur, V | 1 |
| Bunghez, G | 1 |
| Sartorelli, E | 1 |
| Tomasini, M | 1 |
| Grimaldi, MG | 1 |
| Johansson, BW | 1 |
| Sievers, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000525] | Phase 3 | 233 participants (Actual) | Interventional | 1986-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chlorthalidone and Electrolytes
| Article | Year |
|---|---|
Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Diuretics, Potassium Spari | 2018 |
7 trials available for chlorthalidone and Electrolytes
| Article | Year |
|---|---|
Glucose and insulin levels during diuretic therapy in hypertensive men.
Topics: Adult; Aged; Blood Glucose; Chlorthalidone; Diuretics; Electrolytes; Humans; Hydrochlorothiazide; Hy | 1994 |
Combination therapy with saluretics and atenolol in essential hypertension. Effects on blood pressure, electrolytes and uric acid.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bendroflumethiazide; Chlorthalidone; Diuretics; | 1979 |
Diuretics, serum and intracellular electrolyte levels, and ventricular arrhythmias in hypertensive men.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Chlorthalidone; Double-Blind Method; Electrocardi | 1992 |
Plasma renin activity does not predict the antihypertensive efficacy of chlorthalidone.
Topics: Adult; Aldosterone; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; E | 1987 |
Low-dose diuretic therapy for hypertension.
Topics: Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Electrolytes; Fema | 1986 |
Comparison between alprenolol and chlorthalidone as antihypertensive agents.
Topics: Adult; Alprenolol; Amino Alcohols; Blood Pressure; Body Weight; Chlorthalidone; Clinical Trials as T | 1972 |
Hemodynamic changes in long-term diuretic therapy of essential hypertension. A comparative study of chlorthalidone, polythiazide and hydrochlorothiazide.
Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Chlorthalidone; Electrolytes; Heart Rate; Human | 1970 |
22 other studies available for chlorthalidone and Electrolytes
| Article | Year |
|---|---|
[Intra-and extracellular electrolyte changes in hypertension and their alteration].
Topics: Chlorthalidone; Electrolytes; Humans; Hypertension; Sodium Chloride | 1963 |
[Experimental studies on intracellular and extracellular changes in electrolyte and water content after chlorthalidone treatment].
Topics: Body Weight; Chlorthalidone; Electrolytes; Heart; Kidney; Liver; Muscles; Water; Water-Electrolyte B | 1962 |
[Effect of 1-oxo-3-(3'-sulfamoyl-4'-chlorophenyl)-3-hydroxyisoindolinum on urinary electrolyte excretion in comparison with some other diuretics].
Topics: Chlorthalidone; Diuretics; Electrolytes; Humans; Hydrochlorothiazide | 1963 |
[DIURETIC THERAPY OF DECOMPENSATED HEPATIC CIRRHOSIS].
Topics: Blood Chemical Analysis; Chlorothiazide; Chlorthalidone; Diuresis; Diuretics; Electrolytes; Humans; | 1963 |
[ON ION TRANSPORT BEFORE AND AFTER TREATMENT OF CONGESTIVE HEART FAILURE].
Topics: Chlorthalidone; Coronary Disease; Digitalis Glycosides; Diuretics; Electrolytes; Heart Failure; Huma | 1963 |
[EFFECT OF HYGROTON ON CELL ELECTROLYTES IN PATIENTS WITH ESSENTIAL HYPERTENSION].
Topics: Biopsy; Blood Chemical Analysis; Blood Pressure Determination; Chlorides; Chlorthalidone; Electrolyt | 1964 |
THE ANTIDIURETIC PROPERTIES OF CHLOROTHIAZIDE IN DIABETES INSIPIDUS DOGS. I. EFFECT ON SOLUTE, WATER, AND ELECTROLYTE EXCRETION. REP 582.
Topics: Animals; Bendroflumethiazide; Blood Volume; Body Fluids; Chlorothiazide; Chlorthalidone; Diabetes In | 1963 |
[EXPERIMENTAL STUDIES ON ELECTROLYTE METABOLISM AFTER CHLORTHALIDONE TREATMENT].
Topics: Chlorthalidone; Electrolytes; Inulin; Kidney Function Tests; Muscles; Pharmacology; Rats; Research; | 1964 |
[The action of hygroton on diuresis and electrolyte excretion in patients with edemas of various origins].
Topics: Chlorthalidone; Diuresis; Diuretics; Edema; Electrolytes; Humans | 1960 |
Changes in urinary electrolytes versus serum electrolytes during treatment of primary hypertension with chlorthalidone alone and in combination with spironolactone.
Topics: Adult; Aldosterone; Chlorthalidone; Drug Therapy, Combination; Electrolytes; Humans; Hypertension; M | 1981 |
Relationship between plasma catecholamines and urinary catecholamine excretion rates in normal subjects and certain diseased states.
Topics: Adult; Blood Pressure; Chlorthalidone; Creatinine; Diabetes Mellitus; Electrolytes; Epinephrine; Fem | 1981 |
Effects of chlorthalidone on serum and total body potassium in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Body Weight; Chlorthalidone; Drug Therapy, Combination; Electrolytes | 1976 |
[Diuretic effects of chlorthalidone].
Topics: Chlorthalidone; Diuresis; Electrolytes; Humans | 1979 |
Renin reactivity as a determinant of responsiveness to antihypertensive treatment.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Body Weight; Chlorthalidone; Drug | 1977 |
[Long-term study of the effects of chlorthalidone and amiloride on the renal excretion of electrolytes in patients with vascular hypertension].
Topics: Adult; Aged; Amiloride; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Electrolytes; Fem | 1986 |
The influence of chlorthalidone, etozoline and triamterene on electrolyte and urea concentration gradients in the rat kidney.
Topics: Acetates; Animals; Carbonic Anhydrase Inhibitors; Chlorthalidone; Diuretics; Electrolytes; Female; K | 1968 |
[Angiotensin and saluretics in nephrogenic diabetes insipidus of early infancy].
Topics: Angiotensin II; Body Temperature; Chlorthalidone; Diabetes Insipidus; Electrolytes; Female; Furosemi | 1967 |
The effect of diuretics in late pregnancy on the newborn infant.
Topics: Bendroflumethiazide; Body Fluids; Body Weight; Chlorides; Chlorthalidone; Deuterium; Electrolytes; E | 1970 |
[Furosemide in the treatment of cardiac insufficiency].
Topics: Adult; Aged; Chlorothiazide; Chlorthalidone; Diuresis; Electrolytes; Female; Furosemide; Heart Failu | 1967 |
[Diuretic therapy with chlorthalidone in congestive heart failure caused by chronic cor pulmonale].
Topics: Adult; Aged; Chlorthalidone; Chronic Disease; Diuresis; Electrolytes; Heart Failure; Humans; Male; M | 1967 |
[Prolonged treatment of arterial hypertension of arteriosclerotic origin with a combination of chlorthalidone and reserpine].
Topics: Aged; Arteriosclerosis; Blood Glucose; Chlorthalidone; Diuresis; Electrolytes; Female; Hemodynamics; | 1967 |
The effect on serum concentration of sodium, potassium and chloride during long term treatment with some diuretics.
Topics: Alkalosis; Blood; Chlorides; Chlorthalidone; Electrolytes; Humans; Hypokalemia; Potassium; Sodium; T | 1966 |