chlorthalidone has been researched along with Edema in 59 studies
Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorthalidone is a very effective antihypertensive drug, but it has not been studied prospectively in kidney transplant recipients with hypertension." | 9.24 | Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial. ( Hesselink, DA; Hoorn, EJ; Moes, AD; van den Meiracker, AH; Zietse, R, 2017) |
| " After 3 and 6 months of maintenance therapy, blood pressures were measured 24 hours after the previous day's dosing to evaluate the persistence of the antihypertensive effect." | 5.27 | The management of severe hypertension with minoxidil in a once-a-day treatment regimen. ( Bayley, A; Fraser, HS; Hassell, TA; Nicholson, GD, 1985) |
| "Chlorthalidone is a very effective antihypertensive drug, but it has not been studied prospectively in kidney transplant recipients with hypertension." | 5.24 | Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial. ( Hesselink, DA; Hoorn, EJ; Moes, AD; van den Meiracker, AH; Zietse, R, 2017) |
| "Amiloride and chlorthalidone pretreatment induced marked volume depletion, with a 2-3% reduction in body weight, a 5-10% increase in haematocrit and a 14-23% increase in plasma colloid osmotic pressure." | 5.11 | Foot volume increase on nifedipine is not prevented by pretreatment with diuretics. ( Huysmans, FT; van der Heijden, AG; van Hamersvelt, HW, 2004) |
| " In a second case report we describe, in a 61-year-old patient suffering from aspirin-sensitive asthma, recurrent ciliary body oedema with a marked spastic component which was triggered by the medications acetazolamide, dipivefrine and pilocarpine." | 3.69 | Drug-induced ciliary body oedema: a new theory. ( Krieg, PH; Schipper, I, 1996) |
| " Using a simple and convenient once-a-day regimen of minoxidil, nadolol, and chlorthalidone, we treated successfully 30 patients with moderate to severe hypertension." | 3.67 | Minoxidil in a once-a-day step-3 antihypertensive program. ( Alveranga, D; Bazilinski, N; Carroll, HJ; Lazar, I; Oh, MS; Uribarri, J, 1985) |
| "Exchangeable sodium, blood volume, plasma norepinephrine (NE), epinephrine, renin and aldosterone levels, and pressor responses to infused NE or angiotensin II (AII) were assessed in ten patients with essential hypertension on placebo, following 6 to 8 weeks of calcium-antagonist nifedipine (NIF), 3 X 10 to 20 mg/day, and after 6 to 8 weeks on NIF combined with the diuretic chlorthalidone (CHLOR), 25 to 50 mg/day." | 3.67 | Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine. ( Beretta-Piccoli, C; Bianchetti, MG; Bomio, F; Luisoli, S; Marone, C; Weidmann, P, 1985) |
| " After 3 and 6 months of maintenance therapy, blood pressures were measured 24 hours after the previous day's dosing to evaluate the persistence of the antihypertensive effect." | 1.27 | The management of severe hypertension with minoxidil in a once-a-day treatment regimen. ( Bayley, A; Fraser, HS; Hassell, TA; Nicholson, GD, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (94.92) | 18.7374 |
| 1990's | 1 (1.69) | 18.2507 |
| 2000's | 1 (1.69) | 29.6817 |
| 2010's | 1 (1.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moes, AD | 1 |
| Hesselink, DA | 1 |
| van den Meiracker, AH | 1 |
| Zietse, R | 1 |
| Hoorn, EJ | 1 |
| DOUGLAS, A | 1 |
| HALL, R | 1 |
| HORN, DB | 1 |
| KERR, DN | 1 |
| PEARSON, DT | 1 |
| RICHARDSON, H | 1 |
| LINDELL, A | 1 |
| RAUD, MO | 1 |
| WEHLE, B | 1 |
| ARSOV, D | 1 |
| HRISOHO, D | 1 |
| GUCEVA, B | 1 |
| GHIRINGHELLI, L | 1 |
| COMOLI, G | 1 |
| GLASER, E | 1 |
| RUST, S | 1 |
| PISO, HJ | 1 |
| HALFPAP, E | 1 |
| FARIDANI, S | 1 |
| SINGH, A | 1 |
| RAVINA, A | 1 |
| ERICSON, LA | 1 |
| REINHAREZ, D | 1 |
| SELLER, RH | 1 |
| FUCHS, M | 1 |
| SWARTZ, C | 1 |
| BREST, AN | 1 |
| MOYER, JH | 1 |
| LABADIE, P | 1 |
| WOLKERSTORFER, H | 1 |
| SCHUPPIUS, A | 1 |
| SHUBECK, F | 1 |
| TATUM, HJ | 1 |
| BAGROS, P | 1 |
| KUSUMOTO, M | 1 |
| KIYOMIZU, T | 1 |
| CHRISTENSSON, B | 1 |
| GUSTAFSON, A | 1 |
| WESTLING, H | 1 |
| ROMANI, JD | 1 |
| HAEGER, K | 1 |
| KOBAYASHI, K | 1 |
| SHIBATA, M | 1 |
| FUJII, R | 1 |
| KATO, K | 1 |
| IWAZU, A | 1 |
| RAO, CR | 1 |
| GHIRON, G | 1 |
| AVOGADRO, L | 1 |
| SANDERS, JG | 1 |
| GILLIS, OS | 1 |
| MARKETTO, DL | 1 |
| GREADY, TG | 1 |
| KELLER, HM | 1 |
| LINKE, H | 1 |
| RACHID, A | 1 |
| van der Heijden, AG | 1 |
| Huysmans, FT | 1 |
| van Hamersvelt, HW | 1 |
| Webb, EL | 1 |
| Godfrey, JC | 1 |
| Rosenbaum, R | 1 |
| Zisblatt, M | 1 |
| Vukovich, RA | 1 |
| Neiss, ES | 1 |
| Solomon, JG | 1 |
| Krieg, PH | 1 |
| Schipper, I | 1 |
| MacGregor, GA | 1 |
| Tasker, PR | 1 |
| de Wardener, HE | 1 |
| Pinals, RS | 1 |
| Dalakos, TG | 1 |
| Streeten, DH | 1 |
| Descamps, C | 1 |
| Vandenbroucke, JM | 1 |
| van Ypersele de Strihou, C | 1 |
| Oh, MS | 1 |
| Uribarri, J | 1 |
| Alveranga, D | 1 |
| Bazilinski, N | 1 |
| Lazar, I | 1 |
| Carroll, HJ | 1 |
| Nicholson, GD | 1 |
| Fraser, HS | 1 |
| Hassell, TA | 1 |
| Bayley, A | 1 |
| Marone, C | 1 |
| Luisoli, S | 1 |
| Bomio, F | 1 |
| Beretta-Piccoli, C | 1 |
| Bianchetti, MG | 1 |
| Weidmann, P | 1 |
| Haller, J | 1 |
| Fotiu, S | 1 |
| Mroczek, WJ | 1 |
| Davidov, M | 1 |
| Finnerty, FA | 1 |
| Imler, M | 1 |
| Bockel, R | 1 |
| Peter, B | 1 |
| Kieny, R | 1 |
| Stahl, J | 1 |
| Leiter, L | 1 |
| Selchau, M | 1 |
| Schirmböck, J | 1 |
| Schmidt, P | 1 |
| Graudenz, MG | 1 |
| Naess, K | 1 |
| Shah, BR | 1 |
| Desai, NH | 1 |
| Holtmeier, HJ | 1 |
| Steim, H | 1 |
| Danner, H | 1 |
| Marongiu, F | 1 |
| Healy, JJ | 1 |
| Duffy, GJ | 1 |
| Muldowney, FP | 1 |
| D'Alena, P | 1 |
| Robinson, M | 1 |
| Shah, KM | 1 |
| Gulati, OD | 1 |
| Dave, BT | 1 |
| Gokhale, SD | 1 |
| Björkerud, S | 1 |
| Cramér, K | 1 |
| Claro, AL | 1 |
| Müller, W | 1 |
| Mutalik, GS | 1 |
| Angelo, TL | 1 |
| Sölch, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thiazide Diuretics for Hypertension in Kidney Transplant Recipients Using Tacrolimus[NCT02644395] | Phase 3 | 49 participants (Actual) | Interventional | 2013-01-18 | Completed | ||
| Pilot Study to Assess Blockade of Calcium Channels and Sodium Chloride Cotransporters for Physiologic Abnormalities in Liver Transplant Associated Hypertension[NCT05275907] | Phase 4 | 0 participants (Actual) | Interventional | 2022-07-12 | Withdrawn (stopped due to Screened participants did not meet inclusion criteria prior to study completion date) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for chlorthalidone and Edema
| Article | Year |
|---|---|
Combinations of diuretics in the treatment of edema.
Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu | 1970 |
[Diuretics. 47].
Topics: Antihypertensive Agents; Bendroflumethiazide; Chlorothiazide; Chlorthalidone; Clopamide; Dichlorphen | 1970 |
5 trials available for chlorthalidone and Edema
| Article | Year |
|---|---|
Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cr | 2017 |
Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cr | 2017 |
Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cr | 2017 |
Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cr | 2017 |
Foot volume increase on nifedipine is not prevented by pretreatment with diuretics.
Topics: Adult; Amiloride; Ankle; Body Weight; Calcium Channel Blockers; Chlorthalidone; Diuretics; Edema; Fe | 2004 |
Chlorthalidone-triamterene: a potassium-sparing diuretic combination for the treatment of oedema.
Topics: Adult; Aged; Body Weight; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Drug Combin | 1984 |
Antihypertensive efficacy of metolazone.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Chlorthalidone; Diuretics; Edema; | 1974 |
[Clinical and experimental studies on the treatment of traumatic edema].
Topics: Adult; Ankle Injuries; Chlorthalidone; Edema; Fractures, Bone; Humans; Knee Injuries; Male; Sprains | 1971 |
52 other studies available for chlorthalidone and Edema
| Article | Year |
|---|---|
Diuretic response to chlorthalidone.
Topics: Chlorthalidone; Diuretics; Edema; Hypertension | 1961 |
[Treatment of edema in pregnancy with Hygroton].
Topics: Chlorthalidone; Diuretics; Edema; Female; Humans; Pre-Eclampsia; Pregnancy | 1961 |
[Hygroton--a new oral diuretic with protracted effect].
Topics: Chlorthalidone; Dental Care; Diuretics; Edema; Humans; Hypertension | 1960 |
[Hygroton in the treatment of edematous conditions].
Topics: Chlorthalidone; Edema; Edetic Acid | 1962 |
[Urinary aldosterone in edematous patients resistant to chlorthalidone].
Topics: Aldosterone; Chlorthalidone; Diuretics; Edema; Edetic Acid; Humans | 1962 |
[Clinical experiences in the treatment of edematous diseases with Hygroton].
Topics: Ascites; Chlorthalidone; Diuretics; Edema; Heart Failure; Humans; Nephrosis | 1961 |
[Experiences with chlorthalidone (Hygroton)].
Topics: Ascites; Chlorthalidone; Edema; Heart Failure; Liver Cirrhosis | 1963 |
[On the treatment of the edema pregnancy with hygroton].
Topics: Chlorthalidone; Edema; Female; Humans; Pregnancy; Pregnancy Complications | 1962 |
Clinical trial with a new oral diuretic.
Topics: Chlorthalidone; Diuretics; Edema; Humans | 1963 |
[diuretics. Clinical effects of a phthalimidine].
Topics: Chlorthalidone; Diuretics; Edema; Humans; Phthalimides | 1962 |
HYGROTON-INDUCED MYOPIA AND RETINAL EDEMA.
Topics: Chlorthalidone; Edema; Female; Humans; Myopia; Papilledema; Pregnancy; Pregnancy Complications; Reti | 1963 |
[CHRONIC EDEMA OF THE LOWER EXTREMITIES. PHYSIOPATHOLOGY AND TREATMENT].
Topics: Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Extremities; Glycoside Hydrolases; Humans; Lowe | 1963 |
TREATMENT OF EDEMA BY THE COMBINED ADMINISTRATION OF CHEMICALLY DIFFERENT DIURETIC AGENTS.
Topics: Ascites; Chlorthalidone; Diuretics; Edema; Heart Failure; Humans; Hydrochlorothiazide; Organomercury | 1963 |
[RENAL CARBONIC ANHYDRASE: ITS PHYSIOLOGICAL ACTION; ITS INHIBITORS].
Topics: Acetazolamide; Acidosis; Ammonia; Carbonic Anhydrases; Chlorothiazide; Chlorthalidone; Dichlorphenam | 1963 |
[ON THE DOSAGE OF SALURETICS].
Topics: Alkalosis; Chlorthalidone; Diuretics; Edema; Female; Heart Failure; Liver Cirrhosis; Pregnancy; Preg | 1963 |
[CLINICAL EXPERIENCES WITH HYGROTON-RESERPINE].
Topics: Ascites; Chlorthalidone; Edema; Female; Hypertension; Pregnancy; Pregnancy Complications; Reserpine; | 1963 |
PROPHYLACTIC USE OF CHLORTHALIDONE IN PREGNANCY.
Topics: Blood Pressure; Chlorthalidone; Eclampsia; Edema; Female; Humans; Hydrochlorothiazide; Infant, Newbo | 1964 |
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics; | 1964 |
[ON DIURETICS IN THE TREATMENT OF EDEMA IN PREGNANCY].
Topics: Acetazolamide; Chlorothiazide; Chlorthalidone; Diuretics; Edema; Female; Mineralocorticoid Receptor | 1964 |
THE EFFECT OF SALURETICS ON PULSE RATE, BLOOD PRESSURE AND ELECTROCARDIOGRAM DURING EXERCISE IN NORMAL SUBJECTS.
Topics: Aspirin; Biomedical Research; Blood; Blood Pressure; Blood Pressure Determination; Chlorides; Chlort | 1964 |
[THE INTRODUCTION OF ALDOSTERONE ANTAGONISTS IN THERAPY].
Topics: Chlorthalidone; Edema; Humans; Hydrochlorothiazide; Hydroflumethiazide; Mineralocorticoid Receptor A | 1964 |
FURTHER OBSERVATIONS ON THE EFFECT OF DIURETICS ON STASIS EDEMA OF THE LEG.
Topics: Blood Urea Nitrogen; Chlorthalidone; Diuretics; Drug Therapy; Edema; Hydroflumethiazide; Leg; Polyth | 1964 |
[CLINICAL EXPERIENCE OF 2,4,7-TRIAMINO-6-PHENYLPTERIDINE THERAPY UPON LONG TERM AND COMPOUND ADMINISTRATION WITH OTHER AGENTS].
Topics: Adolescent; Biomedical Research; Chlorthalidone; Diuretics; Drug Therapy; Edema; Geriatrics; Hydroch | 1964 |
CLINICAL AND BIOCHEMICAL STUDIES ON A NEW DIURETIC: CHLORTHALIDONE.
Topics: Adolescent; Chlorthalidone; Diuretics; Drug Therapy; Edema; Geriatrics; Heart Failure; Kidney Diseas | 1964 |
[CLINICAL CONTRIBUTION ON THE USE OF THE DIURETIC ASSOCIATION OF CHLORTHALIDONE-TRIAMTERENE].
Topics: Abdominal Neoplasms; Ascites; Biomedical Research; Cardiovascular Diseases; Chlorthalidone; Diuretic | 1964 |
CHLORTHALIDONE IN EDEMA OF PREGNANCY.
Topics: Chlorthalidone; Drug Therapy; Edema; Female; Pre-Eclampsia; Pregnancy; Toxicology | 1965 |
[The action of hygroton on diuresis and electrolyte excretion in patients with edemas of various origins].
Topics: Chlorthalidone; Diuresis; Diuretics; Edema; Electrolytes; Humans | 1960 |
[The effect of hygroton on normal persons, adipose subjects and patients with edemas of various origins].
Topics: Adiposity; Chlorthalidone; Diuretics; Edema; Edetic Acid; Obesity | 1961 |
[The use of a new diuretic, Hygroton, in edemas of various origins].
Topics: Chlorthalidone; Diuretics; Edema; Edetic Acid; Indoles | 1962 |
Lithium toxicity precipitated by a diuretic.
Topics: Bipolar Disorder; Chlorthalidone; Edema; Female; Humans; Lithium; Middle Aged; Patient Compliance; T | 1980 |
Drug-induced ciliary body oedema: a new theory.
Topics: Acetazolamide; Adult; Asthma; Chlorthalidone; Ciliary Body; Diuretics; Edema; Epinephrine; Female; H | 1996 |
Diuretic-induced oedema.
Topics: Adult; Aldosterone; Blood Volume; Body Weight; Chlorthalidone; Diuretics; Edema; Female; Furosemide; | 1975 |
Idiopathic edema as a cause of nonarticular rheumatism.
Topics: Adult; Body Weight; Capillary Permeability; Chlorthalidone; Dextroamphetamine; Edema; Female; Humans | 1979 |
Rhabdomyolysis and acute tubular necrosis associated with carbenoxolone and diuretic treatment.
Topics: Acute Kidney Injury; Carbenoxolone; Chlorthalidone; Edema; Humans; Kidney Tubular Necrosis, Acute; M | 1977 |
Minoxidil in a once-a-day step-3 antihypertensive program.
Topics: Chlorthalidone; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Hypertrichosis; Male | 1985 |
The management of severe hypertension with minoxidil in a once-a-day treatment regimen.
Topics: Adult; Aged; Chlorthalidone; Creatinine; Drug Therapy, Combination; Edema; Female; Humans; Hypertens | 1985 |
Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine.
Topics: Aged; Aldosterone; Angiotensin II; Blood Volume; Calcium; Chlorthalidone; Drug Therapy, Combination; | 1985 |
[Therapy of EPH gestosis].
Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans; | 1973 |
[Importance of hyperammoniemia of the renal origin in the pathogenesis of hepatic coma released in cirrhotic patients by diuretics generating hypokaliemia].
Topics: Acetazolamide; Acid-Base Equilibrium; Alkalosis; Ammonia; Ascites; Chlorides; Chlorthalidone; Edema; | 1969 |
[Diuresis and diuretics].
Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder | 1971 |
[Use of chlorthalidone in patients using oral contraceptives].
Topics: Adult; Body Weight; Chlorthalidone; Contraceptives, Oral; Edema; Epilepsy; Female; Headache; Humans; | 1969 |
[Tendency to edema in withdrawal of diuretics].
Topics: Chlorthalidone; Diuretics; Edema; Female; Humans; Mineralocorticoid Receptor Antagonists; Spironolac | 1970 |
Chlorthalidone as a diuretic agent and its comparative evaluation with polythiazide.
Topics: Chlorthalidone; Edema; Humans; Polythiazide | 1967 |
[On the effects and side effects of a diuretic].
Topics: Chlorthalidone; Diet, Sodium-Restricted; Edema; Humans; Hypertension; Hypokalemia | 1967 |
A comparison of diuretic induced potassium losses in normal and abnormal subjects.
Topics: Chlorthalidone; Edema; Humans; Potassium; Water-Electrolyte Balance | 1968 |
Hygroton-induced myopia.
Topics: Adult; Chlorthalidone; Conjunctivitis; Edema; Female; Humans; Myopia; Orbit | 1969 |
Clinical evaluation of chlorphthalidone--a new non-mercurial diuretic.
Topics: Chlorthalidone; Edema; Humans | 1965 |
[Comparison between furosemide, ethacrynic acid and chlorthalidone in a case with severe edema].
Topics: Aged; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Female; Furosemide; Humans; Male | 1965 |
[Use of 1-oxo-3-(3'-sulfamoyl-4'-chlorophenyl)-3-hydroxyisoindoline in pregnancy edemas].
Topics: Adolescent; Adult; Chlorthalidone; Edema; Female; Humans; Pregnancy; Pregnancy Complications | 1965 |
[Comparative studies on the influence of different antiphlogistics and a diuretic on post-traumatic edema in operated fractures of the tibia].
Topics: Anti-Inflammatory Agents; Body Temperature; Chlorthalidone; Edema; Humans; Oxyphenbutazone; Tibial F | 1965 |
A comparative clinical study of hydrochlorothiazide and chlorthalidone in oedema states.
Topics: Adolescent; Adult; Chlorthalidone; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Male; M | 1966 |
[Polythiazide and chlorthalidone in pregnancy edema].
Topics: Blood Glucose; Blood Pressure; Chlorine; Chlorthalidone; Diuresis; Edema; Female; Humans; Polythiazi | 1966 |