Page last updated: 2024-10-25

chlorthalidone and Carotid Stenosis

chlorthalidone has been researched along with Carotid Stenosis in 3 studies

Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.

Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)

Research Excerpts

ExcerptRelevanceReference
"Asymptomatic carotid stenosis is when this narrowing occurs in people without a history or symptoms of this disease."3.01Pharmacological interventions for asymptomatic carotid stenosis. ( Cassola, N; Clezar, CN; Flumignan, CD; Flumignan, RL; Nakano, LC; Trevisani, VF, 2023)
"Seventy patients with symptomatic carotid artery stenosis were randomized to irbesartan (300 mg/d) or chlorthalidone (50 mg/d) for 4 months before endarterectomy."2.71Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity. ( Bei, R; Bucci, M; Cipollone, F; Cuccurullo, C; Cuccurullo, F; de Cesare, D; De Luca, M; Fazia, M; Iezzi, A; Mezzetti, A; Muraro, R; Pini, B; Spigonardo, F; Ucchino, S; Zucchelli, M, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Clezar, CN1
Flumignan, CD1
Cassola, N1
Nakano, LC1
Trevisani, VF1
Flumignan, RL1
Diener, HC1
Cipollone, F1
Fazia, M1
Iezzi, A1
Pini, B1
Cuccurullo, C1
Zucchelli, M1
de Cesare, D1
Ucchino, S1
Spigonardo, F1
De Luca, M1
Muraro, R1
Bei, R1
Bucci, M1
Cuccurullo, F1
Mezzetti, A1

Reviews

1 review available for chlorthalidone and Carotid Stenosis

ArticleYear
Pharmacological interventions for asymptomatic carotid stenosis.
    The Cochrane database of systematic reviews, 2023, 08-04, Volume: 8

    Topics: Aspirin; Atherosclerosis; Atorvastatin; Carotid Stenosis; Chlorthalidone; Fluvastatin; Hemorrhage; H

2023

Trials

1 trial available for chlorthalidone and Carotid Stenosis

ArticleYear
Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity.
    Circulation, 2004, Mar-30, Volume: 109, Issue:12

    Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agent

2004

Other Studies

1 other study available for chlorthalidone and Carotid Stenosis

ArticleYear
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic

2003