chlorthalidone has been researched along with Arteriosclerosis in 13 studies
Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The VHAS (Verapamil-Hypertension Atherosclerosis Study) Investigators entered 1464 patients with essential hypertension and blood pressure (BP) values > or = 160 mmHg systolic and 95 mmHg diastolic (DBP) but excluded those with a DBP > or = 115 mmHg, and those with diabetes mellitus or previous myocardial infarction or cerebrovascular episodes." | 9.08 | Vascular complications in hypertension: the VHAS study. Verapamil-Hypertension Atherosclerosis Study. ( Zanchetti, A, 1995) |
| "The Verapamil in Hypertension and Atherosclerosis Study (VHAS) is a prospective randomized study the objective of which was to compare the long-term effects of verapamil and chlorthalidone on the blood pressure, clinical safety, and the progression/regression of carotid wall lesions in members of a large population of hypertensive patients." | 9.08 | Clinical results of the Verapamil inHypertension and Atherosclerosis Study. VHAS Investigators. ( Dal Palù, C; Leonetti, G; Magnani, B; Pessina, A; Rosei, EA; Zanchetti, A, 1997) |
| " The present paper reports the principal results of the ultrasound substudy of the randomized, prospective, controlled, Verapamil in Hypertension and Atherosclerosis Study (VHAS)." | 9.08 | The Verapamil in Hypertension and Atherosclerosis Study (VHAS): results of long-term randomized treatment with either verapamil or chlorthalidone on carotid intima-media thickness. ( Dal Palù, C; Leonetti, G; Magnani, B; Pessina, A; Rosei, EA; Zanchetti, A, 1998) |
| " The Verapamil in Hypertension Atherosclerosis Study is an ongoing multicentre randomised double-blind parallel group trial comparing the antihypertensive efficacy of verapamil SR 240 mg/day with that of chlorthalidone 25 mg/day in 1464 patients with essential hypertension aged 40 to 65 years." | 9.07 | Preliminary clinical experience with calcium antagonists in atherosclerosis. Verapamil in Hypertension Atherosclerosis Study Investigators. ( Dal Palù, C; Magnani, B; Zanchetti, A, 1992) |
| "The VHAS (Verapamil-Hypertension Atherosclerosis Study) Investigators entered 1464 patients with essential hypertension and blood pressure (BP) values > or = 160 mmHg systolic and 95 mmHg diastolic (DBP) but excluded those with a DBP > or = 115 mmHg, and those with diabetes mellitus or previous myocardial infarction or cerebrovascular episodes." | 5.08 | Vascular complications in hypertension: the VHAS study. Verapamil-Hypertension Atherosclerosis Study. ( Zanchetti, A, 1995) |
| "The Verapamil in Hypertension and Atherosclerosis Study (VHAS) is a prospective randomized study the objective of which was to compare the long-term effects of verapamil and chlorthalidone on the blood pressure, clinical safety, and the progression/regression of carotid wall lesions in members of a large population of hypertensive patients." | 5.08 | Clinical results of the Verapamil inHypertension and Atherosclerosis Study. VHAS Investigators. ( Dal Palù, C; Leonetti, G; Magnani, B; Pessina, A; Rosei, EA; Zanchetti, A, 1997) |
| " The present paper reports the principal results of the ultrasound substudy of the randomized, prospective, controlled, Verapamil in Hypertension and Atherosclerosis Study (VHAS)." | 5.08 | The Verapamil in Hypertension and Atherosclerosis Study (VHAS): results of long-term randomized treatment with either verapamil or chlorthalidone on carotid intima-media thickness. ( Dal Palù, C; Leonetti, G; Magnani, B; Pessina, A; Rosei, EA; Zanchetti, A, 1998) |
| " The Verapamil in Hypertension Atherosclerosis Study is an ongoing multicentre randomised double-blind parallel group trial comparing the antihypertensive efficacy of verapamil SR 240 mg/day with that of chlorthalidone 25 mg/day in 1464 patients with essential hypertension aged 40 to 65 years." | 5.07 | Preliminary clinical experience with calcium antagonists in atherosclerosis. Verapamil in Hypertension Atherosclerosis Study Investigators. ( Dal Palù, C; Magnani, B; Zanchetti, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SEBRANJOBRIZ, F | 1 |
| BOETTIGER, LE | 1 |
| MALMBORG, RO | 1 |
| MICHAELI, EW | 1 |
| OBROWSKY, L | 1 |
| Mezzetti, A | 1 |
| Fazia, M | 1 |
| Cipollone, F | 1 |
| Rachev, M | 1 |
| Tinterova, Z | 1 |
| Zanchetti, A | 4 |
| Rosei, EA | 2 |
| Dal Palù, C | 3 |
| Leonetti, G | 2 |
| Magnani, B | 3 |
| Pessina, A | 2 |
| Bailey, JM | 1 |
| Randazzo, R | 1 |
| D'Amelio, G | 1 |
| Dalla Volta, S | 1 |
| De Longhi, B | 1 |
| Razzolini, R | 1 |
| Grimaldi, MG | 2 |
| Scalabrino, R | 1 |
6 trials available for chlorthalidone and Arteriosclerosis
| Article | Year |
|---|---|
[New insights on the molecular mechanisms of type-1 angiotensin II receptor blockers and their contribution to atherosclerotic plaque stabilization].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteriosclerosis; Biphenyl Compoun | 2004 |
Vascular complications in hypertension: the VHAS study. Verapamil-Hypertension Atherosclerosis Study.
Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Blood Pressure; Chlorthalidone; Double-Blind | 1995 |
Clinical results of the Verapamil inHypertension and Atherosclerosis Study. VHAS Investigators.
Topics: Adult; Aged; Arteriosclerosis; Blood Pressure; Calcium Channel Blockers; Chlorthalidone; Double-Blin | 1997 |
The Verapamil in Hypertension and Atherosclerosis Study (VHAS): results of long-term randomized treatment with either verapamil or chlorthalidone on carotid intima-media thickness.
Topics: Adult; Anti-Arrhythmia Agents; Antihypertensive Agents; Arteriosclerosis; Basal Metabolism; Blood Pr | 1998 |
Preliminary clinical experience with calcium antagonists in atherosclerosis. Verapamil in Hypertension Atherosclerosis Study Investigators.
Topics: Adult; Aged; Arteriosclerosis; Blood Pressure; Carotid Arteries; Chlorthalidone; Delayed-Action Prep | 1992 |
[Antihypertensive effects of clonidine and of the clonidine-chlorthalidone combination].
Topics: Adult; Aged; Arteriosclerosis; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; | 1974 |
7 other studies available for chlorthalidone and Arteriosclerosis
| Article | Year |
|---|---|
[TREATMENT OF HYPERTENSION WITH HYGROTON-RESERPINE].
Topics: Arteriosclerosis; Chlorthalidone; Clinical Laboratory Techniques; Electrocardiography; Guanethidine; | 1963 |
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine | 1964 |
[CLINICAL EXPERIENCES WITH THE ANTIHYPERTENSIVE AGENT HYGROTON-RESERPINE].
Topics: Antihypertensive Agents; Arteriosclerosis; Biomedical Research; Chlorthalidone; Drug Therapy; Hypert | 1964 |
[Study of the influence of certain salidiuretics on the development of experimental atherosclerosis].
Topics: Animals; Arteriosclerosis; Chlorthalidone; Rabbits; Thiazines | 1967 |
Anti-inflammatory agents in experimental atherosclerosis. Part 2. Failure of antihypertensive drugs to exacerbate atherosclerotic plaque formation.
Topics: Animals; Aorta; Arteriosclerosis; Chlorthalidone; Cholesterol; Cholesterol, Dietary; Disease Models, | 1977 |
[Prolonged treatment of arterial hypertension of arteriosclerotic origin with a combination of chlorthalidone and reserpine].
Topics: Aged; Arteriosclerosis; Blood Glucose; Chlorthalidone; Diuresis; Electrolytes; Female; Hemodynamics; | 1967 |
[Changes in blood uric acid during prolonged treatment with diuretic-hypotensive drugs in aged patients].
Topics: Aged; Arteriosclerosis; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Reserpine; | 1967 |