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chlorthalidone and Arrhythmias, Cardiac

chlorthalidone has been researched along with Arrhythmias, Cardiac in 12 studies

Chlorthalidone: A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to compare the effect of slow-release (SR) nicardipine, placebo and chlorthalidone on hypertension-related arrhythmias evaluating 24-h ambulatory ECG."9.06Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P, 1990)
" Dose-response (10(-7)-10(-4) M) effects of indapamide or chlorthalidone on reperfusion-induced arrhythmias, coronary flow, and heart rate (HR) were evaluated in a randomized blinded fashion."5.29Influence of indapamide and chlorthalidone on reperfusion-induced ventricular fibrillation in isolated guinea pig hearts. ( Fiset, C; Kingma, JG; Kingma, ML; Lacoursière, L; Turgeon, J, 1995)
"In the majority of hypertensive patients, treatment with 50 mg/d of hydrochlorothiazide does not cause marked hypokalemia or ventricular arrhythmias."5.07Diuretics, serum and intracellular electrolyte levels, and ventricular arrhythmias in hypertensive men. ( Black, DM; Cheitlin, MD; Fine, R; Hearst, N; Hulley, SB; Sebastian, A; Seeley, DG; Siegel, D, 1992)
"The aim of the study was to compare the effect of slow-release (SR) nicardipine, placebo and chlorthalidone on hypertension-related arrhythmias evaluating 24-h ambulatory ECG."5.06Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Mureddu, GF; Tammaro, P, 1990)
" Dose-response (10(-7)-10(-4) M) effects of indapamide or chlorthalidone on reperfusion-induced arrhythmias, coronary flow, and heart rate (HR) were evaluated in a randomized blinded fashion."1.29Influence of indapamide and chlorthalidone on reperfusion-induced ventricular fibrillation in isolated guinea pig hearts. ( Fiset, C; Kingma, JG; Kingma, ML; Lacoursière, L; Turgeon, J, 1995)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diener, HC1
Varughese, GI1
Tahrani, AA1
Scarpello, JH1
Papademetriou, V1
Fletcher, R1
Khatri, IM1
Freis, ED1
Caralis, PV1
Materson, BJ1
Perez-Stable, E1
Cembrowski, GS1
Huntington, RW1
Turgeon, J1
Fiset, C1
Kingma, ML1
Lacoursière, L1
Kingma, JG1
Siegel, D1
Hulley, SB2
Black, DM1
Cheitlin, MD1
Sebastian, A1
Seeley, DG1
Hearst, N1
Fine, R1
Galderisi, M1
Celentano, A1
Tammaro, P1
Garofalo, M1
Mureddu, GF1
de Divitiis, O1
Kuller, LH1
Cohen, JD1
Neaton, J1
Stewart, DE1
Ikram, H1
Espiner, EA1
Nicholls, MG1
Brest, AN1
Hueber, EF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000525]Phase 3233 participants (Actual)Interventional1986-07-31Completed
[NCT00000487]Phase 30 participants Interventional1972-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for chlorthalidone and Arrhythmias, Cardiac

ArticleYear
Diuretics, serum and intracellular electrolyte levels, and ventricular arrhythmias in hypertensive men.
    JAMA, 1992, Feb-26, Volume: 267, Issue:8

    Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Chlorthalidone; Double-Blind Method; Electrocardi

1992
Hypertension and arrhythmias: effects of slow-release nicardipine vs chlorthalidone: a double-blind crossover study.
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:10

    Topics: Adult; Arrhythmias, Cardiac; Chlorthalidone; Delayed-Action Preparations; Double-Blind Method; Elect

1990

Other Studies

10 other studies available for chlorthalidone and Arrhythmias, Cardiac

ArticleYear
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic

2003
The putative link between glycemic control and cardiac arrhythmias.
    Archives of internal medicine, 2007, Jul-09, Volume: 167, Issue:13

    Topics: Amlodipine; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Glucose; Chlorthalidone; Diabetes M

2007
Diuretic-induced hypokalemia in uncomplicated systemic hypertension: effect of plasma potassium correction on cardiac arrhythmias.
    The American journal of cardiology, 1983, Nov-01, Volume: 52, Issue:8

    Topics: Adult; Aged; Ambulatory Care; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiac Complexes, Prem

1983
Potassium and diuretic-induced ventricular arrhythmias in ambulatory hypertensive patients.
    Mineral and electrolyte metabolism, 1984, Volume: 10, Issue:3

    Topics: Adult; Aged; Ambulatory Care; Arrhythmias, Cardiac; Benzothiadiazines; Chlorthalidone; Diuretics; El

1984
Probable fatal cardiac dysrhythmia secondary to diuretic-induced hypokalemia.
    The American journal of forensic medicine and pathology, 1981, Volume: 2, Issue:3

    Topics: Adult; Arrhythmias, Cardiac; Chlorthalidone; Death, Sudden; Female; Humans; Hypokalemia

1981
Influence of indapamide and chlorthalidone on reperfusion-induced ventricular fibrillation in isolated guinea pig hearts.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Analysis of Variance; Animals; Arrhythmias, Cardiac; Bradycardia; Chlorthalidone; Coronary Circulati

1995
Unexpected effects of treating hypertension in men with electrocardiographic abnormalities: a critical analysis.
    Circulation, 1986, Volume: 73, Issue:1

    Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiomegaly; Catecholamines; Chlorthalid

1986
Arrhythmogenic potential of diuretic induced hypokalaemia in patients with mild hypertension and ischaemic heart disease.
    British heart journal, 1985, Volume: 54, Issue:3

    Topics: Amiloride; Arrhythmias, Cardiac; Chlorthalidone; Coronary Disease; Cyclopenthiazide; Diuretics; Fema

1985
Management of refractory heart failure.
    Progress in cardiovascular diseases, 1970, Volume: 12, Issue:6

    Topics: Arrhythmias, Cardiac; Benzothiadiazines; Chlorthalidone; Digitalis Glycosides; Diuretics; Heart Fail

1970
[On combined therapy of hypertension and heart insufficiency. Advantages and disadvantages].
    Wiener klinische Wochenschrift, 1966, Oct-07, Volume: 78, Issue:40

    Topics: Arrhythmias, Cardiac; Chlorthalidone; Digitoxin; Drug Synergism; Heart Function Tests; Humans; Hyper

1966