chlortetracycline and Postoperative-Complications

Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Injury; Chloramphenicol; Chlortetracycline; Cholelithiasis; Cholestasis; Erythromycin; Halothane; Heart Valve Prosthesis; Hepatitis A; Humans; Hypoxia; Isoniazid; Jaundice; Liver; Liver Diseases; Methoxyflurane; Necrosis; Pancreatitis; Postoperative Complications; Sulfonamides; Transfusion Reaction

A prospective randomized crossover, within-patient, controlled study was performed in 26 healthy patients to test the effect of the prophylactic local use of gauze drain impregnated with chlortetracycline (Aureomycin 3%, Lederle) ointment on postoperative alveolitis formation after surgical removal of 52 bilaterally impacted mandibular third molars. The teeth were removed on two separate occasions; on one side drain was inserted in the socket, and on the other side no drain treatment was used for control. The influence on postoperative pain, swelling, and mouth opening ability was investigated. The results indicated a statistically significant reduction (P = 0.02) in the incidence of postoperative inflammatory complications, defined as postoperative alveolitis, from 35% in the no-drain group to 4% in the drain group. No statistically significant difference was found between the two treatment methods with regard to pain and mouth opening reduction. There was a significant difference between the drain and no-drain treatment with regard to swelling on the 1st postoperative day in favor of the no-drain method. It is concluded that insertion of a chlortetracycline-impregnated drain may be an effective method for reducing postoperative alveolitis formation but has no beneficial effect on pain, swelling, and mouth opening reduction after impacted mandibular third-molar surgery.

Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Chemoprevention; Chlortetracycline; Cross-Over Studies; Drainage; Dry Socket; Edema; Equipment Design; Female; Follow-Up Studies; Humans; Incidence; Male; Mandible; Molar, Third; Mouth Diseases; Movement; Ointments; Pain, Postoperative; Postoperative Complications; Prospective Studies; Surgical Sponges; Tooth Extraction; Tooth, Impacted

We report on an instructive case of an infrequent but severe complication after paranasal sinus surgery. The use of ointment-covered nasal packing for haemostasis can cause inoculation of ointment into the orbita, if the medical orbital wall has been injured intraoperatively. A postoperative intraorbital haematoma may spread ointment droplets into subcutaneous tissues of the eyelid and cause local sclerosing lipogranulomatosis. The case reported here underlines the resulting therapeutical problems as have been mentioned in the literature. Only complete excision of the lipogranuloma can prevent recurrences. We conclude that ointment should not be used with nasal packings after paranasal sinus surgery if an intraoperative lesion of the orbital wall is likely to occur.

Topics: Administration, Intranasal; Chlortetracycline; Ethmoid Sinus; Eyelid Diseases; Eyelids; Female; Granuloma, Giant Cell; Hemostasis, Surgical; Humans; Middle Aged; Nasal Polyps; Ointments; Paranasal Sinus Neoplasms; Postoperative Complications; Reoperation

Topics: Aortic Valve; Cephalothin; Chloramphenicol; Chlortetracycline; Drug Resistance, Microbial; Endocarditis, Bacterial; Extracorporeal Circulation; Heart Valve Prosthesis; Humans; Kanamycin; Male; Middle Aged; Neomycin; Postoperative Complications; Sepsis; Serratia marcescens; Streptomycin; Sulfadiazine; Transplantation, Homologous

Topics: Anti-Bacterial Agents; Chlortetracycline; Escherichia coli; Gastrectomy; Humans; Intestinal Diseases; Intestines; Lactobacillus; Oxytetracycline; Postoperative Complications; Stomach; Stomach Diseases

Topics: Angiography; Animals; Chlortetracycline; Hepatic Artery; Liver Circulation; Liver Diseases; Necrosis; Postoperative Complications; Swine; Swine Diseases

Topics: Adenocarcinoma; Adult; Blood Coagulation Disorders; Blood Coagulation Tests; Chlortetracycline; Cholecystitis; Female; Gallstones; Gastrointestinal Hemorrhage; Humans; Injections, Intravenous; Middle Aged; Pancreatic Neoplasms; Postoperative Complications

Topics: Bacteria; Chloramphenicol; Chlortetracycline; Escherichia coli Infections; Female; Humans; Infections; Influenza, Human; Intestinal Fistula; Intestinal Neoplasms; Lung Diseases; Male; Middle Aged; Orthomyxoviridae; Oxytetracycline; Penicillin Resistance; Penicillins; Peritonitis; Pleural Diseases; Postoperative Complications; Staphylococcal Infections; Streptomycin; Suppuration; Surgical Wound Infection; Urinary Tract Infections

Topics: Abdominal Neoplasms; Abdominal Wall; Adrenal Cortex Hormones; Antitoxins; Arthroplasty; Chlortetracycline; Cholecystectomy; Gas Gangrene; Geriatrics; Humans; Hypothermia; Hypothermia, Induced; Intestinal Obstruction; Penicillins; Postoperative Care; Postoperative Complications; Surgical Procedures, Operative; Toxins, Biological

Topics: Anti-Bacterial Agents; Bronchial Fistula; Chloramphenicol; Chlortetracycline; Collapse Therapy; Drug Therapy; Empyema; Escherichia coli Infections; Humans; Klebsiella; Penicillins; Pneumonectomy; Polymyxins; Postoperative Complications; Staphylococcal Infections; Streptomycin; Tetracycline; Thoracic Surgery

Topics: Chlortetracycline; Communicable Diseases; Humans; Incidence; Infections; Lung; Penicillins; Postoperative Complications; Pulmonary Surgical Procedures; Streptomycin

Topics: Chlortetracycline; Postoperative Complications

Topics: Chlortetracycline; General Surgery; Humans; Peritonitis; Postoperative Complications; Postoperative Period