chlortetracycline and Intestinal-Diseases

Two similar groups of 14 calves were housed and fed identically in individual pens on a calf-rearing farm. The groups were balanced for weight and immunological status as determined by zinc sulphate turbidity values. When an outbreak of enteric and respiratory disease occurred one group was treated with 20 mg chlortetracycline hydrochloride/kg bodyweight daily for seven consecutive days, by adding the active ingredient to the milk replacer, while the other group was left untreated. Both groups received additional therapy as required. The calves were examined daily during the period of treatment and the clinical observations were assessed and analysed statistically. There was a significant difference between the clinical scores of the two groups on the second day of treatment (P less than 0.05) and on all subsequent days (P less than 0.01) indicating that the calves receiving chlortetracycline hydrochloride were less affected by the disease outbreak. The abnormal enteric and respiratory signs were associated with several potential pathogens including bacteria, viruses and protozoa. The treatment was therefore effective against enteric and respiratory disease involving several organisms.

Topics: Animal Feed; Animals; Cattle; Chlortetracycline; Disease Outbreaks; Enterobacteriaceae; Feces; Food, Formulated; Fungi; Intestinal Diseases; Nasopharynx; Respiratory Tract Infections; Viruses

Topics: Animals; Chlortetracycline; Female; Gastrointestinal Hemorrhage; Intestinal Diseases; Male; Sulfamethazine; Swine; Swine Diseases

Sensitivity of Shigella, pathogenic Escherichia, Proteus and Staphylococcus isolated from children with acute intestinal diseases was studied with respect to antibiotics widely used in medical practice: streptomycin, levomycetin, tetracycline, chlortetracycline, oxytetracycline and neomycin. The antibiotic sensitivity was determined with the method of indicator discs. It was found that sensitivity of shigella was: 44 percent to streptomycin, 69.5 per cent to levomycetin, 18.5 per cent to tetracycline, 18.5 per cent to chlortetracycline, 23 per cent to oxytetracycline and 94 per cent to neomycin. Sensitivity of pathogenic Eschericia was 28, 33, 14, 14, 25 and 74 per cent, sensitivity of staphylococci was 46, 56.5, 21, 21, 31.5 and 89.5 per cent, sensitivity of Proteus was 15, 31.5, 3.5, 3.5, 7.5 and 52.5 per cent respectively. Cross resistance with respect to tetracyclines was found in all the microbes studie. Intragenera differences in the antibiotic sensitivity were observed among Shigella and pathogenic Escherichia.

Topics: Acute Disease; Anti-Bacterial Agents; Child; Chloramphenicol; Chlortetracycline; Drug Resistance, Microbial; Escherichia; Georgia (Republic); Humans; Intestinal Diseases; Microbial Sensitivity Tests; Neomycin; Oxytetracycline; Proteus; Shigella; Species Specificity; Staphylococcus; Streptomycin; Tetracycline

Topics: Animals; Cattle; Cattle Diseases; Chlamydia; Chlamydia Infections; Chlortetracycline; Complement Fixation Tests; Feces; Guinea Pigs; Intestinal Diseases; Mice; Swine; Turkeys

Topics: Anti-Bacterial Agents; Chlortetracycline; Escherichia coli; Gastrectomy; Humans; Intestinal Diseases; Intestines; Lactobacillus; Oxytetracycline; Postoperative Complications; Stomach; Stomach Diseases

Topics: Bacteriology; Chlortetracycline; Enteritis; Enterocolitis; Intestinal Diseases; Micrococcus; Oxytetracycline; Staphylococcal Infections

Topics: Bacteriology; Chlortetracycline; Enteritis; Enterocolitis; Intestinal Diseases; Micrococcus

Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Chlortetracycline; Colitis; Enterocolitis; Intestinal Diseases; Myxedema; Staphylococcal Infections

Topics: Chlortetracycline; Intestinal Diseases; Intestines; Oxytetracycline; Protozoan Infections

Topics: Actinomycosis; Chloramphenicol; Chlortetracycline; Disease; Intestinal Diseases; Intestines

Topics: Amebiasis; Chlortetracycline; Colitis; Dysentery, Amebic; Intestinal Diseases