chlortetracycline and Bacterial-Infections

chlortetracycline has been researched along with Bacterial-Infections* in 35 studies

Reviews

2 review(s) available for chlortetracycline and Bacterial-Infections

ArticleYear
The history of the tetracyclines.
    Annals of the New York Academy of Sciences, 2011, Volume: 1241

    The history of the tetracyclines involves the collective contributions of thousands of dedicated researchers, scientists, clinicians, and business executives over the course of more than 60 years. Discovered as natural products from actinomycetes soil bacteria, the tetracyclines were first reported in the scientific literature in 1948. They were noted for their broad spectrum antibacterial activity and were commercialized with clinical success beginning in the late 1940s to the early 1950s. The second-generation semisynthetic analogs and more recent third-generation compounds show the continued evolution of the tetracycline scaffold toward derivatives with increased potency as well as efficacy against tetracycline-resistant bacteria, with improved pharmacokinetic and chemical properties. Their biologic activity against a wide spectrum of microbial pathogens and their uses in mammalian models of inflammation, neurodegeneration, and other biological systems indicate that the tetracyclines will continue to be successful therapeutics in infectious diseases and as potential therapeutics against inflammation-based mammalian cell diseases.

    Topics: Bacterial Infections; Chlortetracycline; Drug Discovery; History, 20th Century; History, 21st Century; History, Ancient; Humans; Oxytetracycline; Soil Microbiology; Streptomyces aureofaciens; Tetracycline Resistance; Tetracyclines

2011
Public health significance of feeding low levels of antibiotics to animals.
    Advances in applied microbiology, 1973, Volume: 16

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Bacterial Infections; Cattle; Child; Chlortetracycline; Cross Infection; Drug Hypersensitivity; Drug Resistance, Microbial; Female; Food Preservation; Germ-Free Life; Growth; Humans; Male; Meat; Oxytetracycline; Public Health; Rats; Sulfonamides; Time Factors

1973

Trials

2 trial(s) available for chlortetracycline and Bacterial-Infections

ArticleYear
Impact of treatment strategies on cephalosporin and tetracycline resistance gene quantities in the bovine fecal metagenome.
    Scientific reports, 2014, May-29, Volume: 4

    The study objective was to determine the effects of two treatment regimens on quantities of ceftiofur and tetracycline resistance genes in feedlot cattle. The two regimens were ceftiofur crystalline-free acid (CCFA) administered to either one or all steers within a pen and subsequent feeding/not feeding of therapeutic doses of chlortetracycline. A 26-day randomized controlled field trial was conducted on 176 steers. Real-time PCR was used to quantify bla(CMY-2), bla(CTX-M), tet(A), tet(B), and 16S rRNA gene copies/gram of feces from community DNA. A significant increase in ceftiofur resistance and a decrease in tetracycline resistance elements were observed among the treatment groups in which all steers received CCFA treatment, expressed as gene copies/gram of feces. Subsequent chlortetracycline administration led to rapid expansion of both ceftiofur and tetracycline resistance gene copies/gram of feces. Our data suggest that chlortetracycline is contraindicated when attempting to avoid expansion of resistance to critically important third-generation cephalosporins.

    Topics: Animals; Bacteria; Bacterial Infections; Cattle; Cephalosporins; Chlortetracycline; Feces; Metagenome; RNA, Ribosomal, 16S; Tetracycline Resistance

2014
Rifaximin versus chlortetracycline in the short-term treatment of small intestinal bacterial overgrowth.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:5

    Bacterial overgrowth of the small intestine is a condition characterized by nutrient malabsorption due to an excessive number of bacteria in the lumen of the small intestine. Current treatment is based on empirical courses of broad spectrum antibiotics; few controlled data, with respect to the duration and choice of antibiotic drug, exist at present. The recent availability of rifaximin, a non-absorbable rifamycin derivative, highly effective against anaerobic bacteria, prompted us to carry out a randomized, double-blind controlled trial in order to compare its efficacy and tolerability to those of tetracycline, currently considered the first-choice drug.. In 21 patients affected by small intestinal bacterial overgrowth, fasting, peak and total H2 excretion after ingestion of 50 g glucose and severity of symptoms were evaluated before and after a 7-day course of rifaximin, 1200 mg/day (400 mg t.d.s.), or chlortetracycline, 1 g/day (333 mg t.d.s. ).. Fasting, peak and total H2 excretion decreased significantly in the group of patients treated with rifaximin whereas chlortetracycline did not modify these parameters. The H2 breath test normalized in 70% of patients after rifaximin and in 27% of patients after chlortetracycline. The improvement in symptoms was significantly higher in patients treated with rifaximin.. Rifaximin is a promising, easily-handled and safe drug for the short-term treatment of small intestinal bacterial overgrowth.

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Breath Tests; Chlortetracycline; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Hydrogen; Intestine, Small; Male; Middle Aged; Rifamycins; Rifaximin; Treatment Outcome

2000

Other Studies

31 other study(ies) available for chlortetracycline and Bacterial-Infections

ArticleYear
Health and growth performance of barrows reared in all-in/all-out or continuous flow facilities with or without a chlortetracycline feed additive.
    American journal of veterinary research, 1999, Volume: 60, Issue:5

    To compare health and growth performance in barrows reared in all-in/all-out (AIAO) or continuous flow (CF) management systems.. 400 barrows.. Barrows (approx 2 months old) were allotted to 4 replications (100 barrows each); barrows were housed in AIAO or CF rooms (10 pens/room), and 50 pigs/replicate received chlortetracycline (CTC, 110 mg/kg of feed). Barrows from each pen were slaughtered at 3, 4, 5, and 6 months old.. Barrows in the AIAO room had greater total daily gain (TDG) and lean daily gain (LDG) than did barrows in the CF room. Addition of CTC did not improve TDG or LDG in either environment. Barrows in the AIAO room reached body weight of 104.5 kg in 169.7 days, compared with 177.3 days for barrows in the CF room. Feed-to-gain ratio was not affected by management or CTC. Lungs from barrows reared in AIAO facilities had a lower percentage of lesions than did lungs of barrows reared in CF facilities (1.74% vs 9.52%). Addition of CTC did not affect prevalence and extent of lung lesions. Extent of lung lesions was positively correlated with change in serum optical density (OD) to Mycoplasma hyopneumoniae (r = 0.35), but not with change in serum OD to Actinobacillus pleuropneumoniae. Lean growth and serum OD to M. hyopneumoniae and A. pleuropneumoniae were not correlated.. Health and growth performance were better for barrows in an AIAO facility, compared with a CF facility, but addition of CTC to feed failed to enhance health or performance of barrows in either facility.

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Chlortetracycline; Food Additives; Housing, Animal; Ivermectin; Liver; Lung; Male; Orchiectomy; Parasitic Diseases, Animal; Swine; Swine Diseases; Weight Gain

1999
Homeopathy versus antibiotics in metaphylaxis of infectious diseases: a clinical study in pig fattening and its significance to consumers.
    Alternative therapies in health and medicine, 1999, Volume: 5, Issue:5

    Due to the conditions of modern industrial pig fattening in intensive livestock farms, 24% to 69% of the animals become ill. The antibiotic metaphylaxis that is routinely administered leads to several problems in animals, human health, and the environment.. To investigate whether a homeopathic metaphylaxis is effective and potentially useful for replacing antibiotic metaphylaxis.. Animal subjects were divided into groups of 10 per pen, 2 pens sharing 1 trough. Twenty pigs were randomly assigned within a stall and were administered either antibiotics, homeopathy, or placebo.. A typical intensive livestock farm in Northern Germany.. 1440 piglets.. Homeopathic metaphylaxis is compared with placebo, the routine low-dose antibiotic metaphylaxis, and an antibiotic metaphylaxis in therapeutic dosage.. Incidence of diseases in general and of diseases of the respiratory tract.. Homeopathic metaphylaxis is significantly effective compared with placebo and routine low-dose antibiotic metaphylaxis for incidence of disease and rate of disease of the respiratory tract among the animals studied. Only by increasing the dosage of antibiotics to a therapeutic level does antibiotic metaphylaxis surpass homeopathic metaphylaxis.. An unacceptably high percentage of pigs in modern livestock management become ill, suffering mainly from diseases of the respiratory tract. The routine antibiotic dosage of metaphylaxis is too low to be effective. As a result, the problems of resistance and danger to human health and the environment are increasing. To confirm whether antibiotic metaphylaxis may be replaced by homeopathic metaphylaxis, this study should be repeated independently.

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Chlortetracycline; Dimetridazole; Homeopathy; Random Allocation; Respiratory Tract Infections; Sulfamethazine; Swine; Swine Diseases

1999
The antimicrobial actions of taurolin and other preparations on the pathogenic spectrum in dentoalveolar infections.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:3

    Bacteriological specimens from a total of 64 patients with six common, highly relevant clinical indications were collected for an in vitro investigation. By means of standard microbiological methods, 149 species of organism were differentiated, and their relative sensitivity to Taurolin, a broad spectrum chemotherapeutic and antitoxin, as well as 5 conventional finished pharmaceuticals were tested in agar diffusion tests. Taurolin, which was tested in 3 different galenic formulations, produced practically identical, but considerably wider zones of inhibition than all other compared products. In contrast to other substances which exhibited a failure rate of up to 24.8%, no gaps in the activity spectrum in the form of the lack of inhibition zone formation were observed.

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Adhesion; Bacterial Infections; Chlorhexidine; Chlortetracycline; Drug Combinations; Endopeptidases; Humans; Immunodiffusion; Microbial Sensitivity Tests; Neomycin; Periodontal Diseases; Prednisolone; Taurine; Thiadiazines; Urea

1993
Streptobacillus moniliformis epizootic in barrier-maintained C57BL/6J mice and susceptibility to infection of different strains of mice.
    Laboratory animal science, 1990, Volume: 40, Issue:6

    We report a Streptobacillus moniliformis epizootic in barrier-maintained SPF mice. Although various inbred and F1 hybrid strains of mice have been kept in this animal facility, only C57BL/6J Han [corrected] mice showed clinical signs of disease. During the course of the epizootic, 825 breeding animals (approximately 36% of the breeders) died or had to be killed because of severe clinical signs. Although sequential treatment with ampicillin and chlortetracycline gave good therapeutic results, the animal facility was vacated in order to exclude any risk of cross-contamination of the other rodent colonies in our institute. The source and route of transmission of S. moniliformis could not be elucidated. To investigate strain dependent differences experimental infection of different strains of mice with our S. moniliformis isolate was performed. After oral infection only C57BL/6J showed the typical signs of a cervical lymphadenitis and gave an immunological response. BALB/cJ, C3H/He, DBA/2J, CB6F1 and B6D2F1 mice were not affected except in two cases of DBA/2J and B6D2F1 mice where seroconversion was observed. After intravenous infection of C57BL/6J, DBA/2J [corrected] and BALB/cJ all animals showed positive titers in the indirect immunofluorescence test (IIF). One hundred percent of the C57BL/6J, forty percent of the DBA/2J, and none of the BALB/cJ mice developed severe symptoms. The results demonstrate that the susceptibility to streptobacillosis is predominantly influenced by genetic factors.

    Topics: Ampicillin; Animal Husbandry; Animals; Bacterial Infections; Chlortetracycline; Cross Infection; Disease Outbreaks; Female; Mice; Mice, Inbred C57BL; Streptobacillus

1990
The synergistic activity of tiamulin and chlortetracycline: in-feed treatment of bacterially complicated enzootic pneumonia in fattening pigs.
    The Veterinary record, 1986, Aug-02, Volume: 119, Issue:5

    The antibacterial effects of a combination of tiamulin and chlortetracycline in vitro against a number of field isolates of Pasteurella multocida, Haemophilus pleuropneumoniae and Bordetella bronchiseptica were examined. There was a marked synergism between the two antibiotics against all eight isolates of P multocida, against seven of nine isolates of H pleuropneumoniae and against the single strain of B bronchiseptica tested. Two field trials were carried out on a herd with a history of complicated enzootic pneumonia where the presence of Mycoplasma hyopneumoniae and P multocida had been established and subsequently the presence of H pleuropneumoniae was discovered. Feed containing tiamulin at 100 ppm combined with chlortetracycline at 300 ppm was given for seven days to pigs affected with pneumonia, and the results were compared with untreated controls and pigs receiving chlortetracycline at 300 ppm. There was a follow-up observation period of three weeks when all groups received unmedicated feed. During the medication period the combination treated groups showed a statistically significant increase in average daily weight gain of 156 g (20.4 per cent) and in feed conversion efficiency of 0.576 (20.8 per cent) and a numerical improvement in average disease score in comparison with the untreated controls. These improvements were approximately double those observed in the groups treated with 300 ppm chlortetracycline which showed improvements of 93 g (12.2 per cent) in average daily gain and 0.301 (10.9 per cent) in feed conversion efficiency. During the following three weeks most of the initial gains were lost, probably owing to the reinfection of the treated groups by the untreated controls.

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Bacterial Infections; Chlortetracycline; Diterpenes; Drug Synergism; Drug Therapy, Combination; Microbial Sensitivity Tests; Pneumonia; Pneumonia of Swine, Mycoplasmal; Swine; Swine Diseases

1986
A mail survey of the efficacy of prophylactic medication in feed and/or water of feedlot calves.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1985, Volume: 49, Issue:1

    A mail survey of feedlot owners was conducted to evaluate the efficacy of prophylactic antimicrobials, given in the water, or in the ration at preventing illness and/or death. One hundred and twenty-seven farmers from southwestern Ontario collaborated in the study. The percentage of calves requiring individual antimicrobial treatment, for any reason within 28 days of arrival was 22.6% (median 17.8%) and 0.6% (median 0.2%) died in that period. The use of medicated starter rations was not associated with either treatment or mortality rates until the effects of a number of other variables were controlled, analytically. Thereafter, the use of medicated feed was associated with a decrease in mortality rate, but was unrelated to morbidity rate. Overall, the use of medicated water was not associated with treatment or mortality rates. The use of sulphonamides was associated with decreased morbidity, but increased mortality rates. After controlling, analytically using multiple regression, the effects of other variables, the use of medicated water was associated with a significant increase in mortality rates. The other major factors which influenced mortality rates were the number of calves per group, the number of subgroups of calves in each group and whether the group contained cattle from different sources; all were related to increased mortality rates. During a two year period, more feedlot owners appeared to be using medicated rations as opposed to medicated water, as a means of providing antimicrobials to their newly arrived calves.

    Topics: Animal Feed; Animals; Bacterial Infections; Canada; Cattle; Cattle Diseases; Chlortetracycline; Sulfamethazine; Water Supply

1985
Clinical and pathological spectrum of antibiotic-associated colitis.
    The American journal of gastroenterology, 1978, Volume: 69, Issue:3 Pt 1

    Topics: Adolescent; Adult; Aged; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cephalothin; Chlortetracycline; Clindamycin; Diarrhea; Enterocolitis, Pseudomembranous; Female; Humans; Lincomycin; Male; Middle Aged; Sigmoidoscopy

1978
Severe endemic trachoma in Tunisia. I. Effect of topical chemotherapy on conjunctivitis and ocular bacteria.
    The British journal of ophthalmology, 1974, Volume: 58, Issue:10

    Topics: Administration, Topical; Adolescent; Adult; Bacterial Infections; Boric Acids; Child; Child, Preschool; Chlortetracycline; Conjunctivitis; Erythromycin; Eye Diseases; Female; Haemophilus; Humans; Male; Microbial Sensitivity Tests; Moraxella; Seasons; Streptococcus; Trachoma; Tunisia

1974
Twenty-fifth anniversary of the discovery of Aureomycin: the place of the tetracyclines in antimicrobial therapy.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:1

    Topics: Bacterial Infections; Chlortetracycline; Drug Resistance, Microbial; History, 20th Century; Structure-Activity Relationship; Tetracycline; United States

1974
[Methodological aspects in bacteriological study of bronchopulmonary diseases in the child. Initial results].
    Minerva pediatrica, 1974, Mar-03, Volume: 26, Issue:7

    Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cephalothin; Child; Child, Preschool; Chlortetracycline; Gentamicins; Humans; Infant; Neomycin; Penicillins; Respiratory Tract Infections; Rifampin; Streptomycin

1974
Tolypomycin, a new antibiotic. V. In vitro and in vivo antimicrobial activity.
    The Journal of antibiotics, 1972, Volume: 25, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chloramphenicol; Chlortetracycline; Dihydrostreptomycin Sulfate; Drug Stability; Erythromycin; Gastric Juice; Hydrogen-Ion Concentration; Kanamycin; Male; Mice; Microbial Sensitivity Tests; Novobiocin; Penicillin Resistance; Penicillins; Pneumococcal Infections; Rifampin; Solutions; Staphylococcal Infections; Staphylococcus; Streptococcal Infections

1972
[PECULIARITIES IN THE CLINICAL COURSE OF ACUTE BACTERIAL DYSENTERY AND NONSPECIFIC PHAGOCYTOSIS ACTIVITY IN PATIENTS TREATED WITH ACTH AND ANTIBIOTICS].
    Antibiotiki, 1964, Volume: 9

    Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacillus; Bacterial Infections; Chloramphenicol; Chlortetracycline; Dysentery; Dysentery, Bacillary; Humans; Phagocytosis; Sulfathiazoles

1964
Antibiotics in poultry meat preservation. Development in vitro of bacterial resistance to chlortetracycline.
    Applied microbiology, 1960, Volume: 8

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacterial Infections; Chlortetracycline; Dermatologic Agents; In Vitro Techniques; Meat; Meat-Packing Industry; Poultry

1960
[Appearance of crossed resistance in the tetracyclines and differences in their in vitro activity on bacterial].
    Die Medizinische, 1955, Nov-12, Issue:46

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chlortetracycline; In Vitro Techniques; Microbial Sensitivity Tests; Oxytetracycline; Tetracycline; Tetracyclines

1955
Cross-resistance among 3 tetracyclines.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1954, Volume: 85, Issue:1

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chlortetracycline; Microbial Sensitivity Tests; Oxytetracycline; Protein Synthesis Inhibitors; Tetracycline; Tetracyclines

1954
The relation of the in vitro sensitivity test to the clinical response to aureomycin therapy.
    Surgery, 1954, Volume: 35, Issue:2

    Topics: Bacteria; Bacterial Infections; Chlortetracycline; Humans; In Vitro Techniques; Microbial Sensitivity Tests

1954
[Terramycin, aureomycin and chloromycetin dependent bacteria isolated from patients].
    Ugeskrift for laeger, 1954, Jan-14, Volume: 116, Issue:2

    Topics: Bacteria; Bacterial Infections; Bacteriology; Chloramphenicol; Chlortetracycline; Microbial Sensitivity Tests; Oxytetracycline; Urinary Tract

1954
Bacteriological and chemical properties of tetracycline.
    Svensk farmaceutisk tidskrift, 1954, May-10, Volume: 58, Issue:13

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chlortetracycline; Microbial Sensitivity Tests; Oxytetracycline; Protein Synthesis Inhibitors; Tetracycline

1954
In vitro determinations of bacterial sensitivity to aureomycin.
    Acta pathologica et microbiologica Scandinavica, 1954, Volume: 34, Issue:6

    Topics: Bacteria; Bacterial Infections; Chlortetracycline; In Vitro Techniques; Microbial Sensitivity Tests

1954
[The present status of therapy of rod bacterial infections].
    Zahnarztliche Welt, 1953, Jun-10, Volume: 8, Issue:11

    Topics: Actinomycosis; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacterial Infections; Chlortetracycline; Dermatologic Agents; Humans; Penicillins; Streptomycin

1953
[Experimental studies on increasing bacterial resistance to streptomycin and aureomycin].
    Zeitschrift fur Hygiene und Infektionskrankheiten; medizinische Mikrobiologie, Immunologie und Virologie, 1953, Jan-23, Volume: 136, Issue:3

    Topics: Bacteria; Bacterial Infections; Chlortetracycline; Microbial Sensitivity Tests; Streptomycin

1953
[Antibiotic therapy of bacterial dysentery].
    Nederlands tijdschrift voor geneeskunde, 1953, Dec-26, Volume: 97, Issue:52

    Topics: Anti-Bacterial Agents; Bacillus; Bacterial Infections; Chloramphenicol; Chlortetracycline; Dysentery; Dysentery, Bacillary; Gram-Positive Bacteria; Oxytetracycline

1953
Enterococcal endocarditis: report of a case treated with aureomycin.
    Annals of internal medicine, 1952, Volume: 36, Issue:5

    Topics: Bacterial Infections; Chlortetracycline; Endocarditis; Endocarditis, Bacterial; Heart Diseases

1952
Treatment of nontuberculous bacterial pleural space infections with aureomycin: results of treatment in nine patients; concentration of aureomycin in pleural and pericardial fluid in seven patients.
    Annals of internal medicine, 1952, Volume: 37, Issue:1

    Topics: Bacterial Infections; Chlortetracycline; Humans; Pericardial Effusion; Pleurisy; Thorax

1952
[Aureomycin in the treatment of pulmonary bacterial infections of non-pneumococcic and non-tuberculous origin].
    El Dia medico, 1951, Apr-23, Volume: 23, Issue:20

    Topics: Bacterial Infections; Chlortetracycline; Humans; Lung; Respiratory Tract Infections

1951
Aureomycin therapy in bacterial infections resistant to penicillin and streptomycin.
    Texas state journal of medicine, 1950, Volume: 46, Issue:9

    Topics: Bacterial Infections; Chlortetracycline; Infections; Penicillins; Streptomycin

1950
Aureomycin; report of clinical use in 90 cases of bacterial infection in the oral cavity.
    The New York state dental journal, 1950, Volume: 16, Issue:8

    Topics: Bacterial Infections; Chlortetracycline; Face; Mouth

1950
Ditch-plate method for testing bacterial resistance to antibiotics.
    American journal of clinical pathology, 1950, Volume: 20, Issue:1

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chlortetracycline; Humans

1950
Aureomycin therapy of nonpneumococcic and nontuberculous bacterial pulmonary infections.
    Archives of internal medicine (Chicago, Ill. : 1908), 1949, Volume: 84, Issue:6

    Topics: Bacterial Infections; Chlortetracycline; Lung; Respiratory Tract Infections

1949
PATTERNS OF BACTERIAL RESISTANCE TO PENICILLIN, AUREOMYCIN, AND STREPTOMYCIN.
    The Journal of clinical investigation, 1949, Volume: 28, Issue:5 Pt 1

    Topics: Bacterial Infections; Chlortetracycline; Humans; Penicillin Resistance; Penicillins; Streptomycin

1949
Aureomycin, a new antibiotic; results of laboratory studies and of clinical use in 100 cases of bacterial infections.
    Journal of the American Medical Association, 1948, Nov-27, Volume: 138, Issue:13

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacterial Infections; Chlortetracycline; Dermatologic Agents

1948