Page last updated: 2024-10-25

chlorpyrifos and Spastic Paraplegia, Hereditary

chlorpyrifos has been researched along with Spastic Paraplegia, Hereditary in 1 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Spastic Paraplegia, Hereditary: A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hein, ND1
Stuckey, JA1
Rainier, SR1
Fink, JK1
Richardson, RJ1

Other Studies

1 other study available for chlorpyrifos and Spastic Paraplegia, Hereditary

ArticleYear
Constructs of human neuropathy target esterase catalytic domain containing mutations related to motor neuron disease have altered enzymatic properties.
    Toxicology letters, 2010, Jul-01, Volume: 196, Issue:2

    Topics: Carboxylic Ester Hydrolases; Catalytic Domain; Chlorpyrifos; Enzyme Inhibitors; Humans; Hydrolysis;

2010