chlorpyrifos has been researched along with Parkinson Disease in 4 studies
Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dieldrin was without effect but Ni(2+) produced a pattern resembling that of diazinon." | 1.37 | Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo. ( Seidler, FJ; Slotkin, TA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheikh, A | 1 |
| Sheikh, K | 1 |
| Slotkin, TA | 1 |
| Seidler, FJ | 1 |
| Blumrosen, G | 1 |
| Uziel, M | 1 |
| Rubinsky, B | 1 |
| Porrat, D | 1 |
| Zhang, J | 1 |
4 other studies available for chlorpyrifos and Parkinson Disease
| Article | Year |
|---|---|
The expression change of glial fibrillary acidic protein and tyrosine hydroxylase in substantia nigra of the Wistar rats exposed to chlorpyrifos: a novel environmental risk factor for Parkinson's disease.
Topics: Animals; Chlorpyrifos; Dopaminergic Neurons; Glial Fibrillary Acidic Protein; Parkinson Disease; Rat | 2020 |
Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo.
Topics: Animals; Animals, Newborn; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Diazinon; Dieldrin; Gene | 2011 |
Noncontact tremor characterization using low-power wideband radar technology.
Topics: Algorithms; Arm; Equipment Design; Feasibility Studies; Humans; Models, Biological; Optics and Photo | 2012 |
Basic gait analysis based on continuous wave radar.
Topics: Female; Fourier Analysis; Gait; Hemiplegia; Humans; Male; Parkinson Disease; Radar; Sex Factors | 2012 |