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chlorpyrifos and Obesity

chlorpyrifos has been researched along with Obesity in 13 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
" Therefore, we constructed microbiome abundant environment models, focusing on their regulatory effects on the obesity induced by the exogenous chemical chlorpyrifos (CPF) and the related mechanisms."8.12A microbiome abundant environment remodels the intestinal microbiota and improves resistance to obesity induced by chlorpyrifos in mice. ( Chen, A; Hou, H; Li, P; Liang, Y; Liu, D; Ma, X; Wang, P; Wei, Y; Yao, J; Zhou, Z, 2022)
"The results showed that chlorpyrifos caused broken integrity of the gut barrier, leading to increased lipopolysaccharide entry into the body and finally low-grade inflammation, while genetic background and diet pattern have limited influence on the chlorpyrifos-induced results."7.91Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota. ( Cheng, Z; Han, J; Liang, Y; Liu, C; Liu, D; Liu, X; Luo, M; Wang, P; Zhan, J; Zhou, Z, 2019)
" For instance, intake of the pesticide of chlorpyrifos can promote obesity and insulin resistance through influencing gut and gut microbiota of mice."5.01Gut microbiota: An underestimated and unintended recipient for pesticide-induced toxicity. ( Fu, Z; Jin, C; Jin, Y; Ni, Y; Pan, Z; Yuan, X, 2019)
"The results showed that chlorpyrifos caused broken integrity of the gut barrier, leading to increased lipopolysaccharide entry into the body and finally low-grade inflammation, while genetic background and diet pattern have limited influence on the chlorpyrifos-induced results."3.91Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota. ( Cheng, Z; Han, J; Liang, Y; Liu, C; Liu, D; Liu, X; Luo, M; Wang, P; Zhan, J; Zhou, Z, 2019)
" We examined body weight status, food and water intake, lipid and glucose homeostasis, metabolic biomarkers concentrations, insulin levels and insulin resistance, and leptin and ghrelin profiles."3.81Adulthood dietary exposure to a common pesticide leads to an obese-like phenotype and a diabetic profile in apoE3 mice. ( Basaure, P; Cabré, M; Domingo, JL; Peris-Sampedro, F; Reverte, I; Teresa Colomina, M, 2015)
"Chlorpyrifos (CPF) is an organophosphorus pesticide widely and extensively used in agriculture in more than one hundred countries and found ubiquitously in the environment."1.56Obesogenic effects of chlorpyrifos and its metabolites during the differentiation of 3T3-L1 preadipocytes. ( Basaure, P; Biosca-Brull, J; Blanco, J; Cabré, M; Colomina, MT; Domingo, JL; Guardia-Escote, L; Mulero, M; Sánchez, DJ, 2020)
"The prevalence of obesity is increasing at an alarming rate in the United States with 36."1.46Effects of acute exposure to chlorpyrifos on cholinergic and non-cholinergic targets in normal and high-fat fed male C57BL/6J mice. ( Howell, GE; Kondakala, S; Lee, JH; Ross, MK, 2017)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's5 (38.46)24.3611
2020's6 (46.15)2.80

Authors

AuthorsStudies
Kondakala, S2
Ross, MK2
Chambers, JE1
Howell, GE2
Li, P2
Ma, X1
Liu, D2
Wei, Y1
Hou, H1
Yao, J1
Chen, A1
Liang, Y2
Zhou, Z2
Wang, P2
Peng, FJ1
Lin, CA1
Wada, R1
Bodinier, B1
Iglesias-González, A1
Palazzi, P1
Streel, S1
Guillaume, M1
Vuckovic, D1
Chadeau-Hyam, M1
Appenzeller, BMR1
Czajka, M1
Sawicki, K1
Matysiak-Kucharek, M1
Kruszewski, M1
Kurzepa, J1
Wojtyła-Buciora, P1
Kapka-Skrzypczak, L1
Blanco, J1
Guardia-Escote, L1
Mulero, M1
Basaure, P2
Biosca-Brull, J1
Cabré, M2
Colomina, MT1
Domingo, JL2
Sánchez, DJ1
Wang, B1
Tsakiridis, EE1
Zhang, S1
Llanos, A1
Desjardins, EM1
Yabut, JM1
Green, AE1
Day, EA1
Smith, BK1
Lally, JSV1
Wu, J1
Raphenya, AR1
Srinivasan, KA1
McArthur, AG1
Kajimura, S1
Patel, JS1
Wade, MG1
Morrison, KM1
Holloway, AC1
Steinberg, GR1
Lee, JH1
Zhan, J1
Luo, M1
Han, J1
Liu, X1
Liu, C1
Cheng, Z1
Yuan, X1
Pan, Z1
Jin, C1
Ni, Y1
Fu, Z1
Jin, Y1
Peris-Sampedro, F1
Reverte, I1
Teresa Colomina, M1
Meggs, WJ1
Brewer, KL1
Levin, ED1
Schutz, Y1
Ravussin, E1
Diethelm, R1
Jequier, E1

Reviews

2 reviews available for chlorpyrifos and Obesity

ArticleYear
Gut microbiota: An underestimated and unintended recipient for pesticide-induced toxicity.
    Chemosphere, 2019, Volume: 227

    Topics: Animals; Chlorpyrifos; Environmental Pollution; Gastrointestinal Microbiome; Gastrointestinal Tract;

2019
Fetal nicotinic overload, blunted sympathetic responsivity, and obesity.
    Birth defects research. Part A, Clinical and molecular teratology, 2005, Volume: 73, Issue:7

    Topics: Adipose Tissue; Animals; Central Nervous System; Chlorpyrifos; Energy Metabolism; Female; Nicotine;

2005

Other Studies

11 other studies available for chlorpyrifos and Obesity

ArticleYear
Effect of high fat diet on the toxicokinetics and toxicodynamics of chlorpyrifos following acute exposure in male C57BL/6J mice.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:6

    Topics: Acetylcholinesterase; Animals; Chlorpyrifos; Cholinesterase Inhibitors; Diet, High-Fat; Endocannabin

2022
A microbiome abundant environment remodels the intestinal microbiota and improves resistance to obesity induced by chlorpyrifos in mice.
    Environmental pollution (Barking, Essex : 1987), 2022, Dec-15, Volume: 315

    Topics: Animals; Chlorpyrifos; Ecosystem; Gastrointestinal Microbiome; Humans; Intestines; Mice; Mice, Inbre

2022
Association of hair polychlorinated biphenyls and multiclass pesticides with obesity, diabetes, hypertension and dyslipidemia in NESCAV study.
    Journal of hazardous materials, 2024, 01-05, Volume: 461

    Topics: Adult; Cardiovascular Diseases; Chlorpyrifos; Diabetes Mellitus; Dyslipidemias; Environmental Pollut

2024
Exposure to Chlorpyrifos Alters Proliferation, Differentiation and Fatty Acid Uptake in 3T3-L1 Cells.
    International journal of molecular sciences, 2023, Nov-07, Volume: 24, Issue:22

    Topics: 3T3-L1 Cells; Adipogenesis; Animals; Cell Differentiation; Cell Proliferation; Chlorpyrifos; Diabete

2023
Obesogenic effects of chlorpyrifos and its metabolites during the differentiation of 3T3-L1 preadipocytes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 137

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Cell Differentiation; Cell Survival; Chlorpyrifos;

2020
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue.
    Nature communications, 2021, 08-27, Volume: 12, Issue:1

    Topics: Adipose Tissue, Brown; AMP-Activated Protein Kinase Kinases; Animals; Chlorpyrifos; Cyclic AMP; Ener

2021
Effects of acute exposure to chlorpyrifos on cholinergic and non-cholinergic targets in normal and high-fat fed male C57BL/6J mice.
    Toxicology and applied pharmacology, 2017, 12-15, Volume: 337

    Topics: Acetylcholinesterase; Activation, Metabolic; Amidohydrolases; Animals; Arachidonic Acids; Carboxylic

2017
Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota.
    Microbiome, 2019, 02-11, Volume: 7, Issue:1

    Topics: Animals; Body Weight; Chlorpyrifos; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Insecticid

2019
Adulthood dietary exposure to a common pesticide leads to an obese-like phenotype and a diabetic profile in apoE3 mice.
    Environmental research, 2015, Volume: 142

    Topics: Animals; Apolipoprotein E3; Blood Glucose; Body Weight; Chlorpyrifos; Cholesterol; Cholinesterases;

2015
Toxicant exposures and the obesity epidemic.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:2

    Topics: Adult; Child; Chlorpyrifos; Environmental Exposure; Humans; Insecticides; Obesity

2010
Spontaneous physical activity measured by radar in obese and control subject studied in a respiration chamber.
    International journal of obesity, 1982, Volume: 6, Issue:1

    Topics: Adult; Breath Tests; Calorimetry, Indirect; Energy Metabolism; Environment, Controlled; Female; Huma

1982