Page last updated: 2024-10-25

chlorpyrifos and Neuroleptic Malignant Syndrome

chlorpyrifos has been researched along with Neuroleptic Malignant Syndrome in 1 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
"Bromocriptine treatment was offered, which resolved the clinical picture."1.72Neuroleptic malignant syndrome associated with acute organophosphate poisoning: Case report ( Angulo, NY; Castaño, PA; Gómez, CC; Quintero, S, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Angulo, NY1
Castaño, PA1
Gómez, CC1
Quintero, S1

Other Studies

1 other study available for chlorpyrifos and Neuroleptic Malignant Syndrome

ArticleYear
Neuroleptic malignant syndrome associated with acute organophosphate poisoning: Case report
    Biomedica : revista del Instituto Nacional de Salud, 2022, 09-02, Volume: 42, Issue:3

    Topics: Antipsychotic Agents; Bromocriptine; Chlorpyrifos; Humans; Male; Middle Aged; Neuroleptic Malignant

2022