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chlorpyrifos and Disease Models, Animal

chlorpyrifos has been researched along with Disease Models, Animal in 43 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"0mg/kg, but at a lower dosage (0."5.46Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. ( Armstrong, NH; Buchanan, AT; Carr, RL; Eells, JB; Mohammed, AN; Nail, CA; Ross, MK, 2017)
"Chlorpyrifos (CPF) is a broad spectrum, highly effective organophosphorus (OP) pesticide that has been largely used worldwide."5.37Repeated exposure to chlorpyrifos alters the performance of adolescent male rats in animal models of depression and anxiety. ( Chen, WQ; Li, J; Li, YF; Su, RB; Xue, R; Yuan, L; Zhang, YZ, 2011)
"Chlorpyrifos (CHL) is a commonly used organophosphate (OP) pesticide which irreversibly inhibits acetylcholinesterase activity in the CNS."5.30Hypothermia and delayed fever in the male and female rat exposed to chlorpyrifos. ( Gordon, CJ; Grantham, TA; Yang, Y, 1997)
"We used a mouse model of GWI by exposing mice repeatedly to a combination of Gulf War chemicals (pyridostigmine bromide, permethrin, DEET, and chlorpyrifos) and mild immobilization stress, followed by investigating their pain susceptibilities and fatigue symptoms."4.02Exposure to Gulf War Illness-related agents leads to the development of chronic pain and fatigue. ( Clark, JD; Goba, L; Huang, TT; Nguyen, H; Sahbaie, P; Sul, J; Suzaki, A, 2021)
" Neurobehavioural effects likely involving serotonin (5-hydroxytryptamine, 5HT) transmission were assessed both in males and females, through the light-dark exploration test to assess CPF effects on anxiety profiles and the forced swimming test to evaluate the response to the 5HT transporter (5HTT) inhibitor fluvoxamine (30 mg/kg)."3.76Gestational exposure to the organophosphate chlorpyrifos alters social-emotional behaviour and impairs responsiveness to the serotonin transporter inhibitor fluvoxamine in mice. ( Calamandrei, G; Ricceri, L; Rungi, A; Sanghez, V; Venerosi, A, 2010)
" Up to 90 days daily oral crude neem oil treatment (5 g/kg body weight) of laboratory mice did not cause any significant changes in weekly body weight gain, nor in serum liver damage indicators, direct bilirubin or total bilirubin."3.72Operational use of neem oil as an alternative anopheline larvicide. Part B: Environmental impact and toxicological potential. ( Awad, OM, 2003)
"Fragile X syndrome is one of the most common monogenic causes of ASD, characterized by a mutation in the X chromosome which alters the expression of the fragile X mental retardation protein (FMRP)."1.72Influence of Gestational Chlorpyrifos Exposure on ASD-like Behaviors in an fmr1-KO Rat Model. ( Cabré, M; Colomina, MT; Giménez, E; Guardia-Escote, L; Matamala Montoya, M; Morales-Navas, M; Perez-Fernandez, C; Sánchez-Santed, F, 2022)
" tenuior extract can prevent the adverse effects of CPF in liver and lung tissues."1.62The protective effects of Ziziphora tenuior L. against chlorpyrifos induced toxicity: Involvement of inflammatory and cell death signaling pathway. ( Beigmohamadi, M; Hosseini, MJ; Kianpour, F; Mohseni, M; Ramazani, A; Sharafi, A; Yazdinezhad, A, 2021)
"Chlorpyrifos (CPF) is a widely used insecticide in pest control, and it can affect aquatic animals by contaminating the water."1.51Chlorpyrifos exposure induces lipid metabolism disorder at the physiological and transcriptomic levels in larval zebrafish. ( Jin, Y; Shen, J; Shen, M; Wang, X; Zhang, X; Zhou, J, 2019)
"The prevalence of obesity is increasing at an alarming rate in the United States with 36."1.46Effects of acute exposure to chlorpyrifos on cholinergic and non-cholinergic targets in normal and high-fat fed male C57BL/6J mice. ( Howell, GE; Kondakala, S; Lee, JH; Ross, MK, 2017)
"0mg/kg, but at a lower dosage (0."1.46Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. ( Armstrong, NH; Buchanan, AT; Carr, RL; Eells, JB; Mohammed, AN; Nail, CA; Ross, MK, 2017)
"Chronic pain is a component of the multisymptom disease known as Gulf War Illness (GWI)."1.43Exposure to Gulf War Illness chemicals induces functional muscarinic receptor maladaptations in muscle nociceptors. ( Cooper, BY; Johnson, RD; Nutter, TJ, 2016)
" Lethality was increased by AM251 with the higher dosage of PO, but no lethality was noted with either dosage of CPO, with or without AM251."1.42The cannabinoid receptor antagonist AM251 increases paraoxon and chlorpyrifos oxon toxicity in rats. ( Liu, J; Pope, C, 2015)
"Chlorpyrifos (CPF) is an organophosphate pesticide."1.40Impaired retention in AβPP Swedish mice six months after oral exposure to chlorpyrifos. ( Cabré, M; Colomina, MT; Domingo, JL; Peris-Sampedro, F; Reverte, I; Salazar, JG; Sánchez-Santed, F, 2014)
"Chlorpyrifos (CPF) is a broad spectrum, highly effective organophosphorus (OP) pesticide that has been largely used worldwide."1.37Repeated exposure to chlorpyrifos alters the performance of adolescent male rats in animal models of depression and anxiety. ( Chen, WQ; Li, J; Li, YF; Su, RB; Xue, R; Yuan, L; Zhang, YZ, 2011)
"Chlorpyrifos (CPF) is an organophosphate pesticide widely used in intensive agriculture."1.37Amyloid β peptide levels increase in brain of AβPP Swedish mice after exposure to chlorpyrifos. ( Cabré, M; Colomina, MT; Domingo, JL; Ribes, D; Salazar, JG; Sanchez-Santed, F, 2011)
" Sea urchins use neurotransmitters as embryonic growth regulatory signals, so that adverse effects on neural substrates for mammalian brain development can be studied in this simple organism."1.34The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine. ( Bezuglov, VV; Buznikov, GA; Lauder, JM; Milosević, I; Nikitina, LA; Rakić, LM; Slotkin, TA, 2007)
" In addition, the time course of dark adaptation were measured in a subset of these rats (6-8/group) eight months after the completion of dosing by determining the flash intensity needed to elicit a 40 microV b-wave at selected intervals after bleaching 90% of the photopigment."1.33Repeated spike exposure to the insecticide chlorpyrifos interferes with the recovery of visual sensitivity in rats. ( Geller, AM; Hunter, DL; Madden, V; Marshall, RS; Peiffer, RL; Sutton, LD, 2005)
"Chlorpyrifos (CHL) is a commonly used organophosphate (OP) pesticide which irreversibly inhibits acetylcholinesterase activity in the CNS."1.30Hypothermia and delayed fever in the male and female rat exposed to chlorpyrifos. ( Gordon, CJ; Grantham, TA; Yang, Y, 1997)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.65)18.2507
2000's9 (20.93)29.6817
2010's26 (60.47)24.3611
2020's6 (13.95)2.80

Authors

AuthorsStudies
Perez-Fernandez, C2
Matamala Montoya, M1
Morales-Navas, M2
Guardia-Escote, L1
Cabré, M4
Colomina, MT4
Giménez, E1
Sánchez-Santed, F4
Sharma, AR1
Batra, G1
Dhir, N1
Jain, A1
Modi, T1
Saini, L1
Thakur, N1
Mishra, A1
Singh, RS1
Singh, A1
Singla, R1
Prakash, A1
Goyal, M1
Bhatia, A1
Medhi, B1
Modi, M1
Nikbin, S1
Derakhshideh, A1
Kanozi, F1
Hozouri Tarighe, M1
Niknia, S1
Khojasteh, Z1
Barzegar Rahatlo, M1
Mousavi, N1
Ghodousi Johari, E1
Arabi, Y1
Afshar, T1
Tousi, H1
Jameie, SB1
Azarbayjani, MA1
Castaño-Castaño, S1
Sánchez-Gil, A1
Teresa Colomina, M1
Leinekugel, X1
Kianpour, F1
Mohseni, M1
Beigmohamadi, M1
Yazdinezhad, A1
Ramazani, A1
Hosseini, MJ1
Sharafi, A1
Nguyen, H1
Sahbaie, P1
Goba, L1
Sul, J1
Suzaki, A1
Clark, JD1
Huang, TT1
Kondakala, S1
Lee, JH1
Ross, MK2
Howell, GE1
Deveci, HA1
Karapehlivan, M1
Cooper, BY3
Flunker, LD1
Johnson, RD3
Nutter, TJ3
Wang, X1
Zhou, J1
Shen, M1
Shen, J1
Zhang, X1
Jin, Y1
Tripathi, S1
Suzuki, N1
Srivastav, AK1
Svensson, RU1
Bannick, NL1
Marin, MJ1
Robertson, LW1
Lynch, CF1
Henry, MD1
Williams, AL1
DeSesso, JM1
Peris-Sampedro, F2
Salazar, JG2
Reverte, I2
Domingo, JL3
Liu, J1
Pope, C1
Chaklader, M1
Law, S1
Basaure, P1
Richendrfer, H2
Creton, R2
Savy, CY1
Fitchett, AE1
McQuade, R1
Gartside, SE1
Morris, CM1
Blain, PG1
Judge, SJ1
Faria, M2
Garcia-Reyero, N1
Padrós, F2
Babin, PJ1
Sebastián, D1
Cachot, J1
Prats, E2
Arick Ii, M1
Rial, E1
Knoll-Gellida, A1
Mathieu, G1
Le Bihanic, F1
Escalon, BL1
Zorzano, A1
Soares, AM2
Raldúa, D2
Carr, RL1
Armstrong, NH1
Buchanan, AT1
Eells, JB1
Mohammed, AN1
Nail, CA1
De Felice, A1
Greco, A1
Calamandrei, G2
Minghetti, L1
Dominah, GA1
McMinimy, RA1
Kallon, S1
Kwakye, GF1
Dodd, CA1
Klein, BG1
Venerosi, A1
Ricceri, L1
Rungi, A1
Sanghez, V1
Gaidukov, L1
Bar, D1
Yacobson, S1
Naftali, E1
Kaufman, O1
Tabakman, R1
Tawfik, DS1
Levy-Nissenbaum, E1
Cole, TB1
Jansen, K1
Park, S1
Li, WF1
Furlong, CE1
Costa, LG1
Chen, WQ1
Yuan, L1
Xue, R1
Li, YF1
Su, RB1
Zhang, YZ1
Li, J1
Ribes, D1
Pelkowski, SD1
Colwill, RM1
Yan, C1
Jiao, L1
Zhao, J1
Yang, H1
Peng, S1
Rowsey, PJ1
Metzger, BL1
Carlson, J1
Gordon, CJ2
Awad, OM1
Aldridge, JE1
Levin, ED1
Seidler, FJ2
Slotkin, TA3
Oliver, CA1
Geller, AM1
Sutton, LD1
Marshall, RS1
Hunter, DL1
Madden, V1
Peiffer, RL1
Duysen, EG1
Li, B1
Darvesh, S1
Lockridge, O1
Buznikov, GA1
Nikitina, LA1
Rakić, LM1
Milosević, I1
Bezuglov, VV1
Lauder, JM1
Grantham, TA1
Yang, Y1
Valberg, PA1

Reviews

3 reviews available for chlorpyrifos and Disease Models, Animal

ArticleYear
Gestational/perinatal chlorpyrifos exposure is not associated with autistic-like behaviors in rodents.
    Critical reviews in toxicology, 2014, Volume: 44, Issue:6

    Topics: Animals; Autistic Disorder; Behavior, Animal; Chlorpyrifos; Disease Models, Animal; Female; Humans;

2014
The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status.
    Advances in experimental medicine and biology, 2010, Volume: 660

    Topics: Animals; Aryldialkylphosphatase; Carboxylesterase; Chlorpyrifos; Disease Models, Animal; Genotype; I

2010
Radio frequency radiation (RFR): the nature of exposure and carcinogenic potential.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: Animals; Biology; Causality; Communications Media; Disease Models, Animal; Electromagnetic Phenomena

1997

Other Studies

40 other studies available for chlorpyrifos and Disease Models, Animal

ArticleYear
Influence of Gestational Chlorpyrifos Exposure on ASD-like Behaviors in an fmr1-KO Rat Model.
    Molecular neurobiology, 2022, Volume: 59, Issue:9

    Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Chlorpyrifos; Disease Models, Animal; Female; F

2022
"Comparative evaluation of different chemical agents induced Autism Spectrum Disorder in experimental Wistar rats".
    Behavioural brain research, 2024, Feb-26, Volume: 458

    Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Chlorpyrifos; Cytokines; Dioxins; Disease Model

2024
Combination effect of exercise training and eugenol supplementation on the hippocampus apoptosis induced by chlorpyrifos.
    Molecular biology reports, 2020, Volume: 47, Issue:8

    Topics: Acetylcholinesterase; Adenosine Triphosphate; Animals; Apoptosis; Avoidance Learning; Brain-Derived

2020
Similarities between the Effects of Prenatal Chlorpyrifos and Valproic Acid on Ultrasonic Vocalization in Infant Wistar Rats.
    International journal of environmental research and public health, 2020, 09-01, Volume: 17, Issue:17

    Topics: Animals; Autism Spectrum Disorder; Chlorpyrifos; Disease Models, Animal; Enzyme Inhibitors; Female;

2020
The protective effects of Ziziphora tenuior L. against chlorpyrifos induced toxicity: Involvement of inflammatory and cell death signaling pathway.
    Journal of ethnopharmacology, 2021, May-23, Volume: 272

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Death; Chlorpyrifos; Disease Models,

2021
Exposure to Gulf War Illness-related agents leads to the development of chronic pain and fatigue.
    Life sciences, 2021, Oct-15, Volume: 283

    Topics: Animals; Chlorpyrifos; Chronic Pain; DEET; Disease Models, Animal; Fatigue; Humans; Mice; Permethrin

2021
Effects of acute exposure to chlorpyrifos on cholinergic and non-cholinergic targets in normal and high-fat fed male C57BL/6J mice.
    Toxicology and applied pharmacology, 2017, 12-15, Volume: 337

    Topics: Acetylcholinesterase; Activation, Metabolic; Amidohydrolases; Animals; Arachidonic Acids; Carboxylic

2017
Chlorpyrifos-induced parkinsonian model in mice: Behavior, histopathology and biochemistry.
    Pesticide biochemistry and physiology, 2018, Volume: 144

    Topics: Animals; Antioxidants; Aryldialkylphosphatase; Brain; Caffeic Acids; Chlorpyrifos; Disease Models, A

2018
Behavioral, cellular and molecular maladaptations covary with exposure to pyridostigmine bromide in a rat model of gulf war illness pain.
    Toxicology and applied pharmacology, 2018, 08-01, Volume: 352

    Topics: Adaptation, Physiological; Animals; Behavior, Animal; Chlorpyrifos; DEET; Disease Models, Animal; Ga

2018
Chlorpyrifos exposure induces lipid metabolism disorder at the physiological and transcriptomic levels in larval zebrafish.
    Acta biochimica et biophysica Sinica, 2019, Sep-06, Volume: 51, Issue:9

    Topics: Animals; Chlorpyrifos; Disease Models, Animal; Insecticides; Larva; Lipid Metabolism; Lipid Metaboli

2019
Response of serum minerals (calcium, phosphate, and magnesium) and endocrine glands (calcitonin cells and parathyroid gland) of Wistar rat after chlorpyrifos administration.
    Microscopy research and technique, 2013, Volume: 76, Issue:7

    Topics: Animals; Chlorpyrifos; Cholinesterase Inhibitors; Disease Models, Animal; Male; Minerals; Organophos

2013
Chronic chlorpyrifos exposure does not promote prostate cancer in prostate specific PTEN mutant mice.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2013, Volume: 32, Issue:1

    Topics: Acetylcholinesterase; Administration, Oral; Animals; Chlorpyrifos; Disease Models, Animal; Disease P

2013
Impaired retention in AβPP Swedish mice six months after oral exposure to chlorpyrifos.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 72

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Chlorpyrifos; Cognition Disorde

2014
The cannabinoid receptor antagonist AM251 increases paraoxon and chlorpyrifos oxon toxicity in rats.
    Neurotoxicology, 2015, Volume: 46

    Topics: Amidohydrolases; Analysis of Variance; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Ca

2015
Alteration of hedgehog signaling by chronic exposure to different pesticide formulations and unveiling the regenerative potential of recombinant sonic hedgehog in mouse model of bone marrow aplasia.
    Molecular and cellular biochemistry, 2015, Volume: 401, Issue:1-2

    Topics: Anemia, Aplastic; Animals; Bone Marrow Cells; Cell Cycle; Chlorpyrifos; Disease Models, Animal; Femu

2015
Chronic exposure to chlorpyrifos triggered body weight increase and memory impairment depending on human apoE polymorphisms in a targeted replacement mouse model.
    Physiology & behavior, 2015, May-15, Volume: 144

    Topics: Analysis of Variance; Animals; Apolipoproteins E; Body Water; Chlorpyrifos; Cholinesterase Inhibitor

2015
Chlorpyrifos and malathion have opposite effects on behaviors and brain size that are not correlated to changes in AChE activity.
    Neurotoxicology, 2015, Volume: 49

    Topics: Acetylcholinesterase; Age Factors; Analysis of Variance; Animals; Animals, Genetically Modified; Anx

2015
Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour.
    Neurotoxicology, 2015, Volume: 50

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Brain; Chlorpyrif

2015
A delayed chronic pain like condition with decreased Kv channel activity in a rat model of Gulf War Illness pain syndrome.
    Neurotoxicology, 2015, Volume: 51

    Topics: Animals; Chlorpyrifos; Cholinesterase Inhibitors; Chronic Pain; Delayed Rectifier Potassium Channels

2015
Zebrafish Models for Human Acute Organophosphorus Poisoning.
    Scientific reports, 2015, Oct-22, Volume: 5

    Topics: Acetylcholinesterase; Animals; Chemical Terrorism; Chlorpyrifos; Disease Models, Animal; Humans; Org

2015
Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development.
    Neurotoxicology, 2017, Volume: 59

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Arachidonic Acids; Chlorpyrifos; Ch

2017
Exposure to Gulf War Illness chemicals induces functional muscarinic receptor maladaptations in muscle nociceptors.
    Neurotoxicology, 2016, Volume: 54

    Topics: Animals; Chemical Warfare Agents; Chlorpyrifos; Chronic Pain; Disease Models, Animal; Ganglia, Spina

2016
Prenatal exposure to the organophosphate insecticide chlorpyrifos enhances brain oxidative stress and prostaglandin E2 synthesis in a mouse model of idiopathic autism.
    Journal of neuroinflammation, 2016, 06-14, Volume: 13, Issue:1

    Topics: Animals; Animals, Newborn; Autistic Disorder; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Dinopr

2016
Zebrafish is a predictive model for identifying compounds that protect against brain toxicity in severe acute organophosphorus intoxication.
    Archives of toxicology, 2017, Volume: 91, Issue:4

    Topics: Animals; Antidotes; Brain; Chlorpyrifos; Disease Models, Animal; Lethal Dose 50; Neuroprotective Age

2017
Acute exposure to chlorpyrifos caused NADPH oxidase mediated oxidative stress and neurotoxicity in a striatal cell model of Huntington's disease.
    Neurotoxicology, 2017, Volume: 60

    Topics: Acetophenones; Animals; Antioxidants; Cells, Cultured; Chlorpyrifos; Corpus Striatum; Curcumin; Dise

2017
Pyrethroid and organophosphate insecticide exposure in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease: an immunohistochemical analysis of tyrosine hydroxylase and glial fibrillary acidic protein in dorsolateral striatu
    Toxicology and industrial health, 2009, Volume: 25, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chlorpyrifos; Disease Models, Animal; Drug Co

2009
Gestational exposure to the organophosphate chlorpyrifos alters social-emotional behaviour and impairs responsiveness to the serotonin transporter inhibitor fluvoxamine in mice.
    Psychopharmacology, 2010, Volume: 208, Issue:1

    Topics: Animals; Anxiety; Behavior, Animal; Chlorpyrifos; Disease Models, Animal; Female; Fluvoxamine; Insec

2010
In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes.
    BMC clinical pharmacology, 2009, Nov-17, Volume: 9

    Topics: Animals; Aryldialkylphosphatase; Chlorpyrifos; Disease Models, Animal; Enzyme Stability; Female; Glu

2009
Repeated exposure to chlorpyrifos alters the performance of adolescent male rats in animal models of depression and anxiety.
    Neurotoxicology, 2011, Volume: 32, Issue:4

    Topics: Age Factors; Animals; Anxiety; Behavior, Animal; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Con

2011
Amyloid β peptide levels increase in brain of AβPP Swedish mice after exposure to chlorpyrifos.
    Current Alzheimer research, 2011, Volume: 8, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Chlorpyrif

2011
Developmental sub-chronic exposure to chlorpyrifos reduces anxiety-related behavior in zebrafish larvae.
    Neurotoxicology and teratology, 2012, Volume: 34, Issue:4

    Topics: Animals; Anxiety Disorders; Behavior, Animal; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Chroni

2012
Repeated exposures to chlorpyrifos lead to spatial memory retrieval impairment and motor activity alteration.
    Neurotoxicology and teratology, 2012, Volume: 34, Issue:4

    Topics: Animals; Behavior, Animal; Chlorpyrifos; Cholinesterase Inhibitors; Disease Models, Animal; Insectic

2012
Effects of exercise conditioning on thermoregulatory responses to repeated administration of chlorpyrifos.
    Environmental research, 2003, Volume: 92, Issue:1

    Topics: Animals; Body Temperature; Body Temperature Regulation; Chlorpyrifos; Disease Models, Animal; Exerci

2003
Operational use of neem oil as an alternative anopheline larvicide. Part B: Environmental impact and toxicological potential.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 2003, Volume: 9, Issue:4

    Topics: Alanine Transaminase; Animals; Anopheles; Aspartate Aminotransferases; Bilirubin; Body Weight; Chlor

2003
Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression.
    Environmental health perspectives, 2005, Volume: 113, Issue:5

    Topics: Animals; Animals, Newborn; Behavior, Animal; Chlorpyrifos; Cognition Disorders; Depression; Disease

2005
Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination.
    Brain research. Developmental brain research, 2005, Jun-30, Volume: 157, Issue:2

    Topics: Adrenergic beta-Agonists; Age Factors; Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Cell

2005
Repeated spike exposure to the insecticide chlorpyrifos interferes with the recovery of visual sensitivity in rats.
    Documenta ophthalmologica. Advances in ophthalmology, 2005, Volume: 110, Issue:1

    Topics: Animals; Chlorpyrifos; Cholinesterases; Contrast Sensitivity; Dark Adaptation; Disease Models, Anima

2005
Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission.
    Toxicology, 2007, Apr-20, Volume: 233, Issue:1-3

    Topics: Acetylcholine; Acetylcholinesterase; Alkaloids; Alzheimer Disease; Animals; Butyrylcholinesterase; C

2007
The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine.
    Brain research bulletin, 2007, Sep-28, Volume: 74, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Chlorpyrifos; Disease Models, Animal; Dose-Response Relations

2007
Hypothermia and delayed fever in the male and female rat exposed to chlorpyrifos.
    Toxicology, 1997, Mar-28, Volume: 118, Issue:2-3

    Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body T

1997