chlorpyrifos has been researched along with Bronchial Hyperreactivity in 3 studies
Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In chlorpyrifos-treated animals, pilocarpine dose-response curves were shifted significantly to the right, demonstrating decreased responsiveness of neuronal M2 receptors." | 1.32 | Mechanisms of organophosphate insecticide-induced airway hyperreactivity. ( Beckles, RA; Fryer, AD; Howard, AS; Jett, DA; Lein, PJ; Yost, BL, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Proskocil, BJ | 2 |
| Grodzki, ACG | 1 |
| Jacoby, DB | 2 |
| Lein, PJ | 3 |
| Fryer, AD | 3 |
| Bruun, DA | 1 |
| Garg, JA | 1 |
| Villagomez, CC | 1 |
| Howard, AS | 1 |
| Yost, BL | 1 |
| Beckles, RA | 1 |
| Jett, DA | 1 |
3 other studies available for chlorpyrifos and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells.
Topics: Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Cell Differentiation; Chlorpyrifos; Cytokine | 2019 |
The influence of sensitization on mechanisms of organophosphorus pesticide-induced airway hyperreactivity.
Topics: Acetylcholine; Animals; Antibodies, Neutralizing; Asthma; Bronchial Hyperreactivity; Bronchoalveolar | 2015 |
Mechanisms of organophosphate insecticide-induced airway hyperreactivity.
Topics: Animals; Bronchial Hyperreactivity; Chlorpyrifos; Cholinesterase Inhibitors; Guinea Pigs; Insecticid | 2004 |