Page last updated: 2024-10-25

chlorpyrifos and Body Weight

chlorpyrifos has been researched along with Body Weight in 74 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" To investigate whether pesticides would induce insulin resistance/obesity through interfering with mucus-bacterial interactions, we conducted a study to determine how long-term exposure to chlorpyrifos affected C57Bl/6 and CD-1 (ICR) mice fed high- or normal-fat diets."7.91Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota. ( Cheng, Z; Han, J; Liang, Y; Liu, C; Liu, D; Liu, X; Luo, M; Wang, P; Zhan, J; Zhou, Z, 2019)
"Chlorpyrifos (CPF) is an organophosphorus pesticide widely used in agricultural applications and household environments."5.46Protective properties of 6-gingerol-rich fraction from Zingiber officinale (Ginger) on chlorpyrifos-induced oxidative damage and inflammation in the brain, ovary and uterus of rats. ( Abolaji, AO; Afolabi, TT; Arowoogun, MD; Farombi, EO; Nwawolor, D; Ojo, M, 2017)
" Mice in group I (control) were dosed with vegetable oil, while those in group II were given CPF (21."5.34Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effect of vitamin C. ( Akanbi, D; Ambali, S; Ayo, J; Igbokwe, N; Kawu, M; Shittu, M, 2007)
" To investigate whether pesticides would induce insulin resistance/obesity through interfering with mucus-bacterial interactions, we conducted a study to determine how long-term exposure to chlorpyrifos affected C57Bl/6 and CD-1 (ICR) mice fed high- or normal-fat diets."3.91Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota. ( Cheng, Z; Han, J; Liang, Y; Liu, C; Liu, D; Liu, X; Luo, M; Wang, P; Zhan, J; Zhou, Z, 2019)
" Also the levels of testosterone, thyroxine levels, steroidogenic enzyme 17-ketosteroid reductase, body weight, food intake, and relative weight of reproductive organs were decreased."3.83Protective role of Nigella sativa oil against reproductive toxicity, hormonal alterations, and oxidative damage induced by chlorpyrifos in male rats. ( Mantovani, A; Maranghi, F; Mosbah, R; Yousef, MI, 2016)
" We examined body weight status, food and water intake, lipid and glucose homeostasis, metabolic biomarkers concentrations, insulin levels and insulin resistance, and leptin and ghrelin profiles."3.81Adulthood dietary exposure to a common pesticide leads to an obese-like phenotype and a diabetic profile in apoE3 mice. ( Basaure, P; Cabré, M; Domingo, JL; Peris-Sampedro, F; Reverte, I; Teresa Colomina, M, 2015)
" Up to 90 days daily oral crude neem oil treatment (5 g/kg body weight) of laboratory mice did not cause any significant changes in weekly body weight gain, nor in serum liver damage indicators, direct bilirubin or total bilirubin."3.72Operational use of neem oil as an alternative anopheline larvicide. Part B: Environmental impact and toxicological potential. ( Awad, OM, 2003)
"Hypothermia is a commonly reported thermoregulatory response in rodents acutely exposed to organophosphates (OP); however, our laboratory has recently found a delayed hyperthermic response following the initial hypothermia when exposed to the OP, chlorpyrifos."3.69Tolerance to the hypothermic and hyperthermic effects of chlorpyrifos. ( Gordon, CJ; Johnson Rowsey, P, 1997)
"In chlorpyrifos-treated animals, we have observed a significant decrease in the protein expression level of Bcl-2, but a remarkable increase in the expression levels of Bax, cytochrome c, caspase-8, and caspase-9 in both cerebrum and cerebellum."1.51Quercetin plays protective role in oxidative induced apoptotic events during chronic chlorpyrifos exposure to rats. ( Chadha, VD; Dhawan, DK; Fereidouni, S; Kumar, RR, 2019)
"Chlorpyrifos is a commonly-used pesticide which was reported to interfere with hormone signaling and metabolism, however, little is known about its effect on gut microbiota."1.48Chronic chlorpyrifos exposure elicits diet-specific effects on metabolism and the gut microbiome in rats. ( Fang, B; Li, JW; Pang, GF; Ren, FZ; Zhang, M, 2018)
" During spring migration, sparrows were captured, held and dosed by gavage daily for 3 days with either the vehicle control, low (10% LD50) or high (25% LD50) doses of imidacloprid or chlorpyrifos and tested in migratory orientation trials pre-exposure, post-exposure and during recovery."1.46Imidacloprid and chlorpyrifos insecticides impair migratory ability in a seed-eating songbird. ( Eng, ML; Morrissey, CA; Stutchbury, BJM, 2017)
"Chlorpyrifos (CPF) is a widely used organophosphorus pesticide with developmental neurotoxicity such as morphogenesis toxicity."1.46Mother gestational exposure to organophosphorus pesticide induces neuron and glia loss in daughter adult brain. ( Chao, YS; Chen, WZ; Chen, XP; Dong, JY, 2017)
"Chlorpyrifos (CPF) is an organophosphorus pesticide widely used in agricultural applications and household environments."1.46Protective properties of 6-gingerol-rich fraction from Zingiber officinale (Ginger) on chlorpyrifos-induced oxidative damage and inflammation in the brain, ovary and uterus of rats. ( Abolaji, AO; Afolabi, TT; Arowoogun, MD; Farombi, EO; Nwawolor, D; Ojo, M, 2017)
"Body weights were significantly lower than control until PND6."1.42Effect on the H19 gene methylation of sperm and organs of offspring after chlorpyrifos-methyl exposure during organogenesis period. ( Jeong, SH; Kang, HG; Kim, JS; Park, SW; Park, YI; Seo, JH; Shin, HS; Son, SW, 2015)
" total erythrocyte counts, hemoglobin concentration, hematocrit and total leukocyte were observed in the high dosed group as compared to control and other low dosed fed birds."1.42Impact of chlorpyrifos on health biomarkers of broiler chicks. ( Ahmad, MZ; Hussain, I; Javed, MT; Khan, A, 2015)
" This exposure resulted in the accumulation of 2-AG and AEA in the forebrain of juvenile rats; however, even at the lowest dosage level used (1."1.40Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition. ( Carr, RL; Graves, CA; Mangum, LC; Nail, CA; Ross, MK, 2014)
"Chlorpyrifos (CPF) is an organophosphorus cholinesterase inhibitor widely used as an insecticide."1.40Neurologic dysfunction and genotoxicity induced by low levels of chlorpyrifos. ( Attademo, A; Chialvo, D; Hess, L; Lajmanovich, R; Lavarello, S; Muller, M; Poletta, G; Scremin, O; Simoniello, MF; Tardivo, A; Yodice, A, 2014)
"Chlorpyrifos was administered orally to male rats at 0, 2."1.40Effects of chlorpyrifos on reproductive toxicology of male rats. ( Bo, C; Guo, Q; Li, L; Li, X; Liu, Y; Sai, L; Xie, L; Yu, G; Zhang, Z, 2014)
" (no observed adverse effects level, NOAEL) and 1."1.37Adverse effects of exposure to low doses of chlorpyrifos in lactating rats. ( Mansour, SA; Mossa, AT, 2011)
" (no observed adverse effects level, NOAEL) and 1."1.36Adverse effects of lactational exposure to chlorpyrifos in suckling rats. ( Mansour, SA; Mossa, AH, 2010)
" Other than decreased body weight in the higher dosage groups, no effects on physical or reflex development were observed."1.35Developmental chlorpyrifos and methyl parathion exposure alters radial-arm maze performance in juvenile and adult rats. ( Carr, RL; Chambers, JE; Givaruangsawat, S; Johnson, FO; Nail, CA, 2009)
"Chlorpyrifos treatment resulted in a significant decrease in the serum zinc concentrations."1.34Zinc mediates normalization of hepatic drug metabolizing enzymes in chlorpyrifos-induced toxicity. ( Dani, V; Dhawan, DK; Goel, A, 2007)
" Mice in group I (control) were dosed with vegetable oil, while those in group II were given CPF (21."1.34Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effect of vitamin C. ( Akanbi, D; Ambali, S; Ayo, J; Igbokwe, N; Kawu, M; Shittu, M, 2007)
" The sixth acute CPF dose significantly disrupted the SDT in all dosed groups."1.33Effects of chronic dietary and repeated acute exposure to chlorpyrifos on learning and sustained attention in rats. ( Bushnell, PJ; Hunter, DL; Samsam, TE, 2005)
"Chlorpyrifos treatment to normal control animals resulted in a significant decrease in TLC and ZPP concentration after 4 and 8 weeks."1.33Role of zinc in mitigating the toxic effects of chlorpyrifos on hematological alterations and electron microscopic observations in rat blood. ( Dani, V; Dhawan, DK; Goel, A, 2006)
" These same parameters also were examined in mesocosms dosed with 200 microg/L of chlorpyrifos to evaluate responses under more environmentally realistic conditions."1.33Cholinesterase activity and behavior in chlorpyrifos-exposed Rana sphenocephala tadpoles. ( Bidwell, JR; Widder, PD, 2006)
"0 mg/kg/day chosen to define dose-response patterns."1.31Lack of carcinogenicity of chlorpyrifos insecticide in a high-dose, 2-year dietary toxicity study in Fischer 344 rats. ( Mattsson, JL; Yano, BL; Young, JT, 2000)
" Moreover, dose-related inhibition of brain ChE was similar between age groups, and similar reductions in both QNB and epibatidine binding were noted between the age groups after repeated dosing, even though by the end of the dosing period young animals (juveniles) were still about 3 times more sensitive than adults, based on acute lethality."1.31Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats. ( Olivier, K; Pope, CN; Won, YK; Zheng, Q, 2000)
" Toxicity was limited to the highest dosage level (5 mg/kg/day) and, in the dams, consisted of muscle fasciculation, hyperpnea, and hyperreactivity."1.31Lack of selective developmental neurotoxicity in rat pups from dams treated by gavage with chlorpyrifos. ( Garman, RH; Hanley, TR; Hoberman, AM; Maurissen, JP, 2000)
"Chlorpyrifos treatment diminished serum and hepatic zinc levels significantly (p < 0."1.31Protective effects of zinc in chlorpyrifos induced hepatotoxicity: a biochemical and trace elemental study. ( Chauhan, DP; Dhawan, DK; Goel, A, 2000)
" The rats received one of the following regimens: a low-dosage (3 mg/kg) from PND 1-21; a medium dosage (mg/kg from PND 1-5, and then 6 mg/kg from PND 7-21; or a high-dosage schedule of 3 mg/kg on PND 1-5, then 6 mg/kg from PND 7-13, and 12 mg/kg from PND 15-21."1.31Effects of repeated oral postnatal exposure to chlorpyrifos on open-field behavior in juvenile rats. ( Carr, RL; Chambers, HW; Chambers, JE; Guarisco, JA; Richardson, JR; Tang, J, 2001)
"When chlorpyrifos was administered later, on days 11-14, the major target for cell loss shifted from the brainstem to the forebrain and in this case, effects were seen at doses that did not compromise survival or growth."1.30Chlorpyrifos interferes with cell development in rat brain regions. ( Campbell, CG; Seidler, FJ; Slotkin, TA, 1997)
"Pretreatment with mecamylamine caused a decline in DNA synthesis by itself, but nevertheless prevented the effect of chlorpyrifos."1.29Developmental neurotoxicity of chlorpyrifos: cellular mechanisms. ( Seidler, FJ; Slotkin, TA; Whitney, KD, 1995)
" Contrary to prediction, rats dosed with the OP diisopropylfluorophosphate (DFP) showed progressive and persistent impairment of cognitive and motor function over a 3-week period of daily exposure, despite neurochemical and pharmacological evidence of tolerance to its inhibition of ChE."1.29Behavioral and neurochemical effects of acute chlorpyrifos in rats: tolerance to prolonged inhibition of cholinesterase. ( Bushnell, PJ; Padilla, S; Pope, CN, 1993)
" Adult hens were dosed daily for 20 days with CPS (10 mg/kg/day po in 2 ml/kg corn oil) or corn oil (vehicle control) (2 ml/kg/day po) and observed for an additional 4 weeks."1.29Chlorpyrifos: assessment of potential for delayed neurotoxicity by repeated dosing in adult hens with monitoring of brain acetylcholinesterase, brain and lymphocyte neurotoxic esterase, and plasma butyrylcholinesterase activities. ( Kayyali, US; Moore, TB; Randall, JC; Richardson, RJ, 1993)
" Whereas similar reductions in brain muscarinic receptor binding were noted at GD20 and PND3 in dams and developing brain between acute and repeated dosing regimens, greater changes in [3H]CD and [3H]cytisine binding were evident following repeated exposures."1.29Neurochemical and neurobehavioral effects of repeated gestational exposure to chlorpyrifos in maternal and developing rats. ( Chanda, SM; Pope, CN, 1996)
" These data show that oral administration of chlorpyrifos to rats at parentally toxic dose levels was not embryolethal, embryo/fetotoxic, or teratogenic and did not adversely affect fertility or the function or structure of the reproductive organs."1.29Evaluation of the developmental and reproductive toxicity of chlorpyrifos in the rat. ( Breslin, WJ; Dittenber, DA; Liberacki, AB; Quast, JF, 1996)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19909 (12.16)18.7374
1990's14 (18.92)18.2507
2000's23 (31.08)29.6817
2010's23 (31.08)24.3611
2020's5 (6.76)2.80

Authors

AuthorsStudies
Mansour, AT1
Hamed, HS1
El-Beltagi, HS1
Mohamed, WF1
Basaure, P4
Guardia-Escote, L2
Biosca-Brull, J2
Blanco, J2
Cabré, M4
Peris-Sampedro, F4
Sánchez-Santed, F2
Domingo, JL3
Colomina, MT3
Gu, J1
Xu, S1
Liu, Y2
Chen, X1
Bagni, T1
Siaussat, D1
Maria, A1
Couzi, P1
Maïbèche, M1
Massot, M1
Verkaik-Schakel, RN1
Pérez-Fernández, C1
Plösch, T1
Guibourdenche, M1
El Khayat El Sabbouri, H1
Bonnet, F1
Djekkoun, N1
Khorsi-Cauet, H2
Corona, A1
Guibourdenche, J1
Bach, V2
Anton, PM1
Gay-Quéheillard, J1
Abolaji, AO1
Ojo, M1
Afolabi, TT1
Arowoogun, MD1
Nwawolor, D1
Farombi, EO1
Fang, B1
Li, JW1
Zhang, M1
Ren, FZ1
Pang, GF1
Eng, ML1
Stutchbury, BJM1
Morrissey, CA1
El-Nahhal, Y1
Lubbad, R1
Aroonvilairat, S1
Tangjarukij, C1
Sornprachum, T1
Chaisuriya, P1
Siwadune, T1
Ratanabanangkoon, K1
Liang, Y1
Zhan, J1
Liu, D1
Luo, M1
Han, J1
Liu, X1
Liu, C1
Cheng, Z1
Zhou, Z1
Wang, P1
Fereidouni, S1
Kumar, RR1
Chadha, VD1
Dhawan, DK4
Carr, RL3
Graves, CA1
Mangum, LC1
Nail, CA2
Ross, MK1
Muller, M1
Hess, L1
Tardivo, A1
Lajmanovich, R1
Attademo, A1
Poletta, G1
Simoniello, MF1
Yodice, A1
Lavarello, S1
Chialvo, D1
Scremin, O1
Mosbah, R1
Yousef, MI1
Maranghi, F1
Mantovani, A1
Shin, HS1
Seo, JH1
Jeong, SH2
Park, SW1
Park, YI1
Son, SW1
Kang, HG2
Kim, JS1
Ahmad, MZ1
Khan, A1
Javed, MT1
Hussain, I1
Reverte, I2
Teresa Colomina, M1
Ezzi, L1
Belhadj Salah, I1
Haouas, Z1
Sakly, A1
Grissa, I1
Chakroun, S1
Kerkeni, E1
Hassine, M1
Mehdi, M1
Ben Cheikh, H1
Reygner, J1
Lichtenberger, L1
Elmhiri, G1
Dou, S1
Bahi-Jaber, N1
Rhazi, L1
Depeint, F1
Abdennebi-Najar, L1
Chen, XP1
Chao, YS1
Chen, WZ1
Dong, JY1
Smida, A1
Ncibi, S1
Taleb, J1
Ben Saad, A1
Ncib, S1
Zourgui, L1
Mage, DT1
Mitra, NK1
Siong, HH1
Nadarajah, VD1
Johnson, FO1
Chambers, JE2
Givaruangsawat, S1
Mansour, SA2
Mossa, AH1
Jiang, W1
Duysen, EG1
Hansen, H1
Shlyakhtenko, L1
Schopfer, LM1
Lockridge, O1
Akhtar, N1
Srivastava, MK1
Raizada, RB1
Mossa, AT1
Sai, L1
Li, X1
Guo, Q1
Xie, L1
Yu, G1
Bo, C1
Zhang, Z1
Li, L1
Qiao, D1
Seidler, FJ5
Padilla, S2
Slotkin, TA6
Volz, DC1
Wirth, EF1
Fulton, MH1
Scott, GI1
Strozier, E1
Block, DS1
Ferry, JL1
Walse, SS1
Chandler, GT1
Ehrich, M1
Hancock, S1
Ward, D1
Holladay, S1
Pung, T1
Flory, L1
Hinckley, J1
Jortner, BS1
Cho, JH1
Kim, DG1
Park, JM1
Cho, MH1
Izrael, M1
Van der Zee, EA1
Yanai, J1
Awad, OM1
Samsam, TE1
Hunter, DL1
Bushnell, PJ2
Brown, KK1
Ferrier, H1
Shaw, G1
Nieuwenhuijsen, M1
Boobis, A1
Elliott, P1
Goel, A3
Dani, V2
Widder, PD1
Bidwell, JR1
Ambali, S1
Akanbi, D1
Igbokwe, N1
Shittu, M1
Kawu, M1
Ayo, J1
Deacon, MM1
Murray, JS1
Pilny, MK1
Rao, KS1
Dittenber, DA2
Hanley, TR2
John, JA1
Chakraborti, TK1
Farrar, JD1
Pope, CN5
Chanda, SM2
Harp, P1
Liu, J1
Whitney, KD1
Richardson, RJ1
Moore, TB1
Kayyali, US1
Randall, JC1
Mattsson, JL2
Wilmer, JW1
Shankar, MR1
Berdasco, NM1
Crissman, JW1
Maurissen, JP2
Bond, DM1
Breslin, WJ1
Liberacki, AB1
Quast, JF1
Campbell, CG1
Johnson Rowsey, P1
Gordon, CJ1
Blakley, BR1
Yole, MJ1
Brousseau, P1
Boermans, H1
Fournier, M1
Yano, BL1
Young, JT1
Zheng, Q1
Olivier, K1
Won, YK1
Hoberman, AM1
Garman, RH1
Chauhan, DP1
Chambers, HW1
Guarisco, JA1
Richardson, JR1
Tang, J1
Muto, MA1
Lobelle, F1
Bidanset, JH1
Wurpel, JN1
Goodman, LR2
Hansen, DJ2
Cripe, GM2
Middaugh, DP1
Moore, JC1
Macauley, SF1
Ogawa, Y1
Suzuki, S1
Uchida, O1
Kamata, E1
Saito, M1
Umemura, T1
Wakana, M1
Kaneko, T1
Kurokawa, Y1
Tobe, M1
Brust, RA1
Miyazaki, S2
Hodgson, GC2
Sherman, M1
Herrick, RB1
Johnson, JC1
Jones, RL1
Leuck, DB1
Bowman, MC1
Knox, FE1
Rotkovská, D1
Moc, J1
Kautská, J1
Bartonícková, A1
Keprtová, J1
Hofer, M1
Kaliada, TV1
Nikitina, VN1
Liashko, GG1
Masterova, IIu1
Shaposhnikova, ES1
Tomashevskaia, LA1
Solenyĭ, EA1

Other Studies

74 other studies available for chlorpyrifos and Body Weight

ArticleYear
Modulatory Effect of Papaya Extract against Chlorpyrifos-Induced Oxidative Stress, Immune Suppression, Endocrine Disruption, and DNA Damage in Female
    International journal of environmental research and public health, 2022, 04-12, Volume: 19, Issue:8

    Topics: Animals; Antioxidants; Body Weight; Carica; Catfishes; Chlorpyrifos; DNA Damage; Female; Hormones; O

2022
Exposure to chlorpyrifos at different ages triggers APOE genotype-specific responses in social behavior, body weight and hypothalamic gene expression.
    Environmental research, 2019, Volume: 178

    Topics: Animals; Apolipoprotein E4; Apolipoproteins E; Behavior, Animal; Body Weight; Chlorpyrifos; Gene Exp

2019
Chlorpyrifos-induced toxicity has no gender selectivity in the early fetal brain.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2020, Volume: 55, Issue:9

    Topics: Acetylcholinesterase; Animals; Body Weight; Brain; Catalase; Chlorpyrifos; Cholinesterase Inhibitors

2020
A maternal effect influences sensitivity to chlorpyrifos pesticide in the pest moth Spodoptera littoralis.
    Ecotoxicology and environmental safety, 2020, Volume: 204

    Topics: Animals; Body Weight; Chlorpyrifos; Epigenesis, Genetic; Female; Insecticide Resistance; Insecticide

2020
Sex and Exposure to Postnatal Chlorpyrifos Influence the Epigenetics of Feeding-Related Genes in a Transgenic
    International journal of environmental research and public health, 2020, 12-29, Volume: 18, Issue:1

    Topics: Animals; Body Weight; Chlorpyrifos; Diet, High-Fat; Epigenesis, Genetic; Female; Genotype; Insectici

2020
Perinatal exposure to chlorpyrifos and/or a high-fat diet is associated with liver damage in male rat offspring.
    Cells & development, 2021, Volume: 166

    Topics: Animals; Biomarkers; Body Weight; Chlorpyrifos; Diet, High-Fat; Energy Metabolism; Gene Expression R

2021
Protective properties of 6-gingerol-rich fraction from Zingiber officinale (Ginger) on chlorpyrifos-induced oxidative damage and inflammation in the brain, ovary and uterus of rats.
    Chemico-biological interactions, 2017, May-25, Volume: 270

    Topics: ADAM17 Protein; Animals; Body Weight; Brain; Catechols; Chlorpyrifos; Fatty Alcohols; Female; Inflam

2017
Chronic chlorpyrifos exposure elicits diet-specific effects on metabolism and the gut microbiome in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 111

    Topics: Animals; Blood Glucose; Body Weight; Chlorpyrifos; Cholinesterase Inhibitors; Diet; Energy Metabolis

2018
Imidacloprid and chlorpyrifos insecticides impair migratory ability in a seed-eating songbird.
    Scientific reports, 2017, 11-09, Volume: 7, Issue:1

    Topics: Animal Migration; Animals; Body Weight; Chlorpyrifos; Insecticides; Neonicotinoids; Nitro Compounds;

2017
Acute and single repeated dose effects of low concentrations of chlorpyrifos, diuron, and their combination on chicken.
    Environmental science and pollution research international, 2018, Volume: 25, Issue:11

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Biomarkers; Body Weight; Chickens; Chlorpyrifos; Di

2018
Effects of topical exposure to a mixture of chlorpyrifos, cypermethrin and captan on the hematological and immunological systems in male Wistar rats.
    Environmental toxicology and pharmacology, 2018, Volume: 59

    Topics: Administration, Topical; Adrenal Glands; Animals; Blood Cell Count; Body Weight; Captan; Chlorpyrifo

2018
Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota.
    Microbiome, 2019, 02-11, Volume: 7, Issue:1

    Topics: Animals; Body Weight; Chlorpyrifos; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Insecticid

2019
Quercetin plays protective role in oxidative induced apoptotic events during chronic chlorpyrifos exposure to rats.
    Journal of biochemical and molecular toxicology, 2019, Volume: 33, Issue:8

    Topics: Acetylcholinesterase; Animals; Apoptosis; Body Weight; Cerebellum; Chlorpyrifos; Cholinesterase Inhi

2019
Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition.
    Neurotoxicology, 2014, Volume: 43

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Arachidonic Acids; Body Weight; Brain;

2014
Neurologic dysfunction and genotoxicity induced by low levels of chlorpyrifos.
    Neurotoxicology, 2014, Volume: 45

    Topics: Acetylcholinesterase; Acoustic Stimulation; Animals; Body Temperature; Body Weight; Butyrylcholinest

2014
Protective role of Nigella sativa oil against reproductive toxicity, hormonal alterations, and oxidative damage induced by chlorpyrifos in male rats.
    Toxicology and industrial health, 2016, Volume: 32, Issue:7

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Antioxidants; Body Weight; Chlorpyrifos; Glutathione; Mal

2016
Effect on the H19 gene methylation of sperm and organs of offspring after chlorpyrifos-methyl exposure during organogenesis period.
    Environmental toxicology, 2015, Volume: 30, Issue:12

    Topics: Animals; Body Weight; Chlorpyrifos; CpG Islands; DNA Methylation; Enzyme-Linked Immunosorbent Assay;

2015
Impact of chlorpyrifos on health biomarkers of broiler chicks.
    Pesticide biochemistry and physiology, 2015, Volume: 122

    Topics: Animals; Biomarkers; Body Weight; Brain; Chickens; Chlorpyrifos; Cholinesterases; Erythrocyte Count;

2015
Adulthood dietary exposure to a common pesticide leads to an obese-like phenotype and a diabetic profile in apoE3 mice.
    Environmental research, 2015, Volume: 142

    Topics: Animals; Apolipoprotein E3; Blood Glucose; Body Weight; Chlorpyrifos; Cholesterol; Cholinesterases;

2015
Histopathological and genotoxic effects of chlorpyrifos in rats.
    Environmental science and pollution research international, 2016, Volume: 23, Issue:5

    Topics: Animals; Body Weight; Bone Marrow; Chlorpyrifos; Comet Assay; DNA Damage; Dose-Response Relationship

2016
Two cholinesterase inhibitors trigger dissimilar effects on behavior and body weight in C57BL/6 mice: The case of chlorpyrifos and rivastigmine.
    Behavioural brain research, 2017, 02-01, Volume: 318

    Topics: Acetylcholinesterase; Animals; Body Weight; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Dose-Res

2017
Inulin Supplementation Lowered the Metabolic Defects of Prolonged Exposure to Chlorpyrifos from Gestation to Young Adult Stage in Offspring Rats.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Animals; Body Weight; Chlorpyrifos; Dietary Supplements; Drinking; Female; Gastrointestinal Microbio

2016
Mother gestational exposure to organophosphorus pesticide induces neuron and glia loss in daughter adult brain.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2017, Volume: 52, Issue:2

    Topics: Animals; Body Weight; Brain; Chlorpyrifos; Female; Male; Maternal Exposure; Mice, Inbred ICR; Neurog

2017
Immunoprotective activity and antioxidant properties of cactus (Opuntia ficus indica) extract against chlorpyrifos toxicity in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 88

    Topics: Animals; Antioxidants; Body Weight; Bone Marrow Cells; Chlorpyrifos; Cholinesterase Inhibitors; Immu

2017
microg/kg-day or microg/day? A commentary on Georgopoulos et al., JESEE 2008.
    Journal of exposure science & environmental epidemiology, 2008, Volume: 18, Issue:6

    Topics: Age Factors; Biomarkers; Body Weight; Chlorpyrifos; Dose-Response Relationship, Drug; Environmental

2008
Evaluation of neurotoxicity of repeated dermal application of chlorpyrifos on hippocampus of adult mice.
    Annals of agricultural and environmental medicine : AAEM, 2008, Volume: 15, Issue:2

    Topics: Acetylcholinesterase; Administration, Cutaneous; Animals; Body Weight; Chlorpyrifos; Cholinesterase

2008
Developmental chlorpyrifos and methyl parathion exposure alters radial-arm maze performance in juvenile and adult rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 109, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Chlorpyrifos; Cholin

2009
Adverse effects of lactational exposure to chlorpyrifos in suckling rats.
    Human & experimental toxicology, 2010, Volume: 29, Issue:2

    Topics: Animals; Animals, Suckling; Biomarkers; Body Weight; Chemical and Drug Induced Liver Injury; Chlorpy

2010
Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 115, Issue:1

    Topics: Animals; Biotinylation; Body Temperature; Body Weight; Brain; Brain Chemistry; Chlorpyrifos; Choline

2010
Assessment of chlorpyrifos toxicity on certain organs in rat, Rattus norvegicus.
    Journal of environmental biology, 2009, Volume: 30, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Cerebellum; Chlorpyrifos; Epididymis; Insecticides; Male

2009
Adverse effects of exposure to low doses of chlorpyrifos in lactating rats.
    Toxicology and industrial health, 2011, Volume: 27, Issue:3

    Topics: Administration, Oral; Animals; Blood Proteins; Body Weight; Chlorpyrifos; Dose-Response Relationship

2011
Effects of chlorpyrifos on reproductive toxicology of male rats.
    Environmental toxicology, 2014, Volume: 29, Issue:9

    Topics: Animals; Base Sequence; Body Weight; Chlorpyrifos; DNA Primers; Gonadal Steroid Hormones; Gonadotrop

2014
Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period?
    Environmental health perspectives, 2002, Volume: 110, Issue:11

    Topics: Animals; Body Weight; Brain; Chlorpyrifos; Choline O-Acetyltransferase; Cholinesterases; DNA; Female

2002
Effects of fipronil and chlorpyrifos on endocrine-related endpoints in female grass shrimp (Palaemonetes pugio).
    Bulletin of environmental contamination and toxicology, 2003, Volume: 71, Issue:3

    Topics: Animals; Body Weight; Chlorpyrifos; Cholesterol; Dose-Response Relationship, Drug; Ecdysteroids; Fem

2003
Neurologic and immunologic effects of exposure to corticosterone, chlorpyrifos, and multiple doses of tri-ortho-tolyl phosphate over a 28-day period in rats.
    Journal of toxicology and environmental health. Part A, 2004, Mar-12, Volume: 67, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Axons; Body Weight; Brain; Cerebral Cortex; Chlorpyrifos; Choline

2004
Chlropyrifos-methyl shows anti-androgenic activity without estrogenic activity in rats.
    Toxicology, 2004, Jul-01, Volume: 199, Issue:2-3

    Topics: Adrenal Glands; Androgen Antagonists; Animals; Body Weight; Chlorpyrifos; Dose-Response Relationship

2004
Cholinergic synaptic signaling mechanisms underlying behavioral teratogenicity: effects of nicotine, chlorpyrifos, and heroin converge on protein kinase C translocation in the intermedial part of the hyperstriatum ventrale and on imprinting behavior in an
    Journal of neuroscience research, 2004, Nov-15, Volume: 78, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Biological Transport; Blotting, W

2004
Operational use of neem oil as an alternative anopheline larvicide. Part B: Environmental impact and toxicological potential.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 2003, Volume: 9, Issue:4

    Topics: Alanine Transaminase; Animals; Anopheles; Aspartate Aminotransferases; Bilirubin; Body Weight; Chlor

2003
The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent.
    Brain research. Developmental brain research, 2005, Aug-08, Volume: 158, Issue:1-2

    Topics: Animals; Animals, Newborn; Body Weight; Central Nervous System; Chlorpyrifos; Female; Insecticides;

2005
Effects of chronic dietary and repeated acute exposure to chlorpyrifos on learning and sustained attention in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 87, Issue:2

    Topics: Animals; Attention; Body Weight; Chlorpyrifos; Cholinesterase Inhibitors; Conditioning, Operant; Die

2005
Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood.
    Environmental health perspectives, 2005, Volume: 113, Issue:10

    Topics: Animals; Animals, Newborn; Body Weight; Chlorpyrifos; Female; Growth; Hyperinsulinism; Hyperlipidemi

2005
Assessment of uncertainty in a probabilistic model of consumer exposure to pesticide residues in food.
    Food additives and contaminants, 2006, Volume: 23, Issue:6

    Topics: Body Weight; Child, Preschool; Chlorpropham; Chlorpyrifos; Diet; Environmental Exposure; Food Contam

2006
Role of zinc in mitigating the toxic effects of chlorpyrifos on hematological alterations and electron microscopic observations in rat blood.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2006, Volume: 19, Issue:5

    Topics: Animals; Blood; Body Weight; Cell Shape; Chlorpyrifos; Erythrocytes; Insecticides; Male; Microscopy,

2006
Cholinesterase activity and behavior in chlorpyrifos-exposed Rana sphenocephala tadpoles.
    Environmental toxicology and chemistry, 2006, Volume: 25, Issue:9

    Topics: Animals; Body Weight; Chlorpyrifos; Cholinesterases; Dose-Response Relationship, Drug; Geologic Sedi

2006
Zinc mediates normalization of hepatic drug metabolizing enzymes in chlorpyrifos-induced toxicity.
    Toxicology letters, 2007, Feb-28, Volume: 169, Issue:1

    Topics: Aminopyrine N-Demethylase; Animals; Body Weight; Chlorpyrifos; Cytochrome P-450 Enzyme System; Cytoc

2007
Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effect of vitamin C.
    The Journal of toxicological sciences, 2007, Volume: 32, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Blood Proteins; Body Weight; Chemistry, Clinical; Chlorpyrifos

2007
Embryotoxicity and fetotoxicity of orally administered chlorpyrifos in mice.
    Toxicology and applied pharmacology, 1980, Jun-15, Volume: 54, Issue:1

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Body Weight; Chlorpyrifos; Cholinesteras

1980
Comparative neurochemical and neurobehavioral effects of repeated chlorpyrifos exposures in young and adult rats.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:1

    Topics: Aging; Animals; Behavior, Animal; Biomarkers; Body Weight; Brain; Brain Chemistry; Chlorpyrifos; Cho

1993
Comparative developmental and maternal neurotoxicity following acute gestational exposure to chlorpyrifos in rats.
    Journal of toxicology and environmental health, 1995, Volume: 44, Issue:2

    Topics: Acetylcholinesterase; Animals; Body Weight; Brain; Chlorpyrifos; Dose-Response Relationship, Drug; E

1995
Developmental neurotoxicity of chlorpyrifos: cellular mechanisms.
    Toxicology and applied pharmacology, 1995, Volume: 134, Issue:1

    Topics: Animals; Animals, Newborn; Body Weight; Brain; Chlorpyrifos; DNA; Mecamylamine; Organ Size; Ornithin

1995
Behavioral and neurochemical effects of acute chlorpyrifos in rats: tolerance to prolonged inhibition of cholinesterase.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Animals; Behavior, Animal; Body Weight; Brain Chemistry; Chlorpyrifos; Cholinesterase Inhibitors; Co

1993
Chlorpyrifos: assessment of potential for delayed neurotoxicity by repeated dosing in adult hens with monitoring of brain acetylcholinesterase, brain and lymphocyte neurotoxic esterase, and plasma butyrylcholinesterase activities.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1993, Volume: 21, Issue:1

    Topics: Acetylcholinesterase; Animals; Body Weight; Brain; Butyrylcholinesterase; Carboxylic Ester Hydrolase

1993
Single-dose and 13-week repeated-dose neurotoxicity screening studies of chlorpyrifos insecticide.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1996, Volume: 34, Issue:4

    Topics: Administration, Oral; Animals; Behavior, Animal; Body Weight; Central Nervous System; Chlorpyrifos;

1996
Neurochemical and neurobehavioral effects of repeated gestational exposure to chlorpyrifos in maternal and developing rats.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:4

    Topics: Acetylcholinesterase; Animals; Avoidance Learning; Behavior, Animal; Body Weight; Brain; Brain Chemi

1996
Evaluation of the developmental and reproductive toxicity of chlorpyrifos in the rat.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 29, Issue:1

    Topics: Administration, Oral; Animals; Animals, Newborn; Body Weight; Brain Chemistry; Chlorpyrifos; Choline

1996
Chlorpyrifos interferes with cell development in rat brain regions.
    Brain research bulletin, 1997, Volume: 43, Issue:2

    Topics: Age Factors; Animals; Body Weight; Brain; Cell Count; Cell Size; Chlorpyrifos; Female; Pregnancy; Ra

1997
Tolerance to the hypothermic and hyperthermic effects of chlorpyrifos.
    Toxicology, 1997, Sep-05, Volume: 121, Issue:3

    Topics: Administration, Oral; Analysis of Variance; Animals; Body Temperature; Body Weight; Chlorpyrifos; Dr

1997
Effect of chlorpyrifos on immune function in rats.
    Veterinary and human toxicology, 1999, Volume: 41, Issue:3

    Topics: Animals; Antibodies; Blood Cells; Body Weight; Chlorpyrifos; Hemolytic Plaque Technique; Immune Syst

1999
Lack of carcinogenicity of chlorpyrifos insecticide in a high-dose, 2-year dietary toxicity study in Fischer 344 rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 53, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Carcinogenicity Tests; Chlorpyrifos; Cholinesterase Inhi

2000
Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 55, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Animals, Suckling; Autonomic Nervous System Diseases; Body Weight;

2000
Lack of selective developmental neurotoxicity in rat pups from dams treated by gavage with chlorpyrifos.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 57, Issue:2

    Topics: Administration, Oral; Animals; Animals, Newborn; Animals, Suckling; Behavior, Animal; Body Weight; B

2000
Protective effects of zinc in chlorpyrifos induced hepatotoxicity: a biochemical and trace elemental study.
    Biological trace element research, 2000, Volume: 74, Issue:2

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Enzymes; Insecticides; M

2000
Effects of repeated oral postnatal exposure to chlorpyrifos on open-field behavior in juvenile rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 59, Issue:2

    Topics: Acetylcholinesterase; Animals; Animals, Newborn; Body Weight; Brain; Butyrylcholinesterase; Chlorpyr

2001
Embryotoxicity and neurotoxicity in rats associated with prenatal exposure to DURSBAN.
    Veterinary and human toxicology, 1992, Volume: 34, Issue:6

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Chlorpyrifos; Embryo, Mammalian; Female; I

1992
A new early life-stage toxicity test using the California grunion (Leuresthes tenuis) and results with chlorpyrifos.
    Ecotoxicology and environmental safety, 1985, Volume: 10, Issue:1

    Topics: Animals; Body Weight; Chlorpyrifos; Fishes; Larva; Seawater; Water Pollutants; Water Pollutants, Che

1985
Early life-stage toxicity test methods for gulf toadfish (Opsanus beta) and results using chlorpyrifos.
    Ecotoxicology and environmental safety, 1986, Volume: 11, Issue:1

    Topics: Animals; Body Weight; Chlorpyrifos; Fishes; Seawater; Water Pollutants; Water Pollutants, Chemical

1986
[28-day repeated dose toxicity test of chlorpyrifos in Wistar rat].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1988, Issue:106

    Topics: Animals; Body Weight; Chlorpyrifos; Eating; Female; Hematologic Tests; Kidney; Lethal Dose 50; Liver

1988
Effect of Dursban in the drinking water of chicks.
    Journal of economic entomology, 1971, Volume: 64, Issue:5

    Topics: Animals; Body Weight; Chickens; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterases; Drinking;

1971
Chronic toxicity of dursban and its metabolite, 3,5,6-trichloro-2-pyridinol in chickens.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Administration, Oral; Alcohols; Animals; Body Weight; Chickens; Chlorpyrifos; Cholinesterases; Culic

1972
Fly control and chronic toxicity from feeding Dursban (O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate) to laying hens.
    Poultry science, 1973, Volume: 52, Issue:2

    Topics: Administration, Oral; Animal Feed; Animals; Body Weight; Chickens; Chlorpyrifos; Cholinesterases; Di

1973
Persistence of chlorpyrifos-methyl in corn silage and effects of feeding dairy cows the treated silage.
    Journal of dairy science, 1974, Volume: 57, Issue:12

    Topics: Alcohols; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cattle; Chl

1974
Evaluation of the biological effects of police radar RAMER 7F.
    Environmental health perspectives, 1993, Volume: 101, Issue:2

    Topics: Animals; Blood; Body Temperature; Body Weight; Cornea; Electromagnetic Phenomena; Female; Femur; Mal

1993
[Experimental research on the biological action of the pulse-modulated microwave radiation created by shipboard radar stations].
    Meditsina truda i promyshlennaia ekologiia, 1995, Issue:11

    Topics: Animals; Behavior, Animal; Body Weight; Male; Microwaves; Radar; Rats; Russia; Ships; Spermatogenesi

1995
[Biological action and hygienic significance of the electromagnetic field created by coastal radar facilities].
    Gigiena i sanitariia, 1986, Issue:7

    Topics: Animals; Body Weight; Dose-Response Relationship, Radiation; Electromagnetic Fields; Electromagnetic

1986