Page last updated: 2024-10-25

chlorpyrifos and Autism Spectrum Disorder

chlorpyrifos has been researched along with Autism Spectrum Disorder in 9 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)

Research Excerpts

ExcerptRelevanceReference
"Neurodevelopmental exposure to chlorpyrifos (CPF) could increase risks for neurological disorders, such as autism spectrum disorder, cognitive impairment, or attention deficit hyperactivity disorder."4.12Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line. ( Tao, J; Tu, Y; Wang, Y; Wu, N; Yang, G; Yang, Y; You, M, 2022)
"Fragile X syndrome is one of the most common monogenic causes of ASD, characterized by a mutation in the X chromosome which alters the expression of the fragile X mental retardation protein (FMRP)."1.72Influence of Gestational Chlorpyrifos Exposure on ASD-like Behaviors in an fmr1-KO Rat Model. ( Cabré, M; Colomina, MT; Giménez, E; Guardia-Escote, L; Matamala Montoya, M; Morales-Navas, M; Perez-Fernandez, C; Sánchez-Santed, F, 2022)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's9 (100.00)2.80

Authors

AuthorsStudies
Lizé, M1
Monfort, C1
Rouget, F1
Limon, G1
Durand, G1
Tillaut, H1
Chevrier, C1
Perez-Fernandez, C4
Matamala Montoya, M1
Morales-Navas, M3
Guardia-Escote, L2
Cabré, M1
Colomina, MT3
Giménez, E2
Sánchez-Santed, F4
Tu, Y2
Yang, Y1
Wang, Y1
Wu, N1
Tao, J1
Yang, G2
You, M2
Sharma, AR1
Batra, G1
Dhir, N1
Jain, A1
Modi, T1
Saini, L1
Thakur, N1
Mishra, A1
Singh, RS1
Singh, A1
Singla, R1
Prakash, A1
Goyal, M1
Bhatia, A1
Medhi, B1
Modi, M1
Aguilera-Sáez, LM1
Abreu, AC1
Fernández, I1
Garrido-Cárdenas, JA1
Castaño-Castaño, S1
Sánchez-Gil, A1
Teresa Colomina, M1
Leinekugel, X1
Berg, EL1
Ching, TM1
Bruun, DA1
Rivera, JK1
Careaga, M1
Ellegood, J1
Lerch, JP1
Wöhr, M1
Lein, PJ1
Silverman, JL1
Biosca-Brull, J1
Mora, S1
Carrillo, B1
Pinos, H1
Conejo, NM1
Collado, P1
Arias, JL1
Martín-Sánchez, F1
He, X1
Song, Y1

Reviews

2 reviews available for chlorpyrifos and Autism Spectrum Disorder

ArticleYear
Relationship between Autism Spectrum Disorder and Pesticides: A Systematic Review of Human and Preclinical Models.
    International journal of environmental research and public health, 2021, 05-13, Volume: 18, Issue:10

    Topics: Autism Spectrum Disorder; Chlorpyrifos; Female; Humans; Pesticides; Pregnancy; Prenatal Exposure Del

2021
The relationship between pesticide exposure during critical neurodevelopment and autism spectrum disorder: A narrative review.
    Environmental research, 2022, Volume: 203

    Topics: Acetylcholinesterase; Autism Spectrum Disorder; Chlorpyrifos; Female; Humans; Pesticides; Pregnancy;

2022

Other Studies

7 other studies available for chlorpyrifos and Autism Spectrum Disorder

ArticleYear
Prenatal exposure to organophosphate pesticides and autism spectrum disorders in 11-year-old children in the French PELAGIE cohort.
    Environmental research, 2022, Volume: 212, Issue:Pt C

    Topics: Acetylcholinesterase; Autism Spectrum Disorder; Child; Chlorpyrifos; Diazinon; Female; Humans; Insec

2022
Influence of Gestational Chlorpyrifos Exposure on ASD-like Behaviors in an fmr1-KO Rat Model.
    Molecular neurobiology, 2022, Volume: 59, Issue:9

    Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Chlorpyrifos; Disease Models, Animal; Female; F

2022
Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line.
    Environmental pollution (Barking, Essex : 1987), 2022, Dec-01, Volume: 314

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Autism Spectrum Disorder; Chlorpyrifos; Cytokines; H

2022
"Comparative evaluation of different chemical agents induced Autism Spectrum Disorder in experimental Wistar rats".
    Behavioural brain research, 2024, Feb-26, Volume: 458

    Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Chlorpyrifos; Cytokines; Dioxins; Disease Model

2024
Medium and long-term effects of low doses of Chlorpyrifos during the postnatal, preweaning developmental stage on sociability, dominance, gut microbiota and plasma metabolites.
    Environmental research, 2020, Volume: 184

    Topics: Adult; Animals; Autism Spectrum Disorder; Chlorpyrifos; Female; Gastrointestinal Microbiome; Humans;

2020
Similarities between the Effects of Prenatal Chlorpyrifos and Valproic Acid on Ultrasonic Vocalization in Infant Wistar Rats.
    International journal of environmental research and public health, 2020, 09-01, Volume: 17, Issue:17

    Topics: Animals; Autism Spectrum Disorder; Chlorpyrifos; Disease Models, Animal; Enzyme Inhibitors; Female;

2020
Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos.
    Journal of neurodevelopmental disorders, 2020, 12-16, Volume: 12, Issue:1

    Topics: Animals; Autism Spectrum Disorder; Brain; Chlorpyrifos; Female; Male; Pregnancy; Prenatal Exposure D

2020